omeprazole and guaifenesin

omeprazole has been researched along with guaifenesin in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.90)18.7374
1990's10 (34.48)18.2507
2000's9 (31.03)29.6817
2010's8 (27.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Asada, S; Hirata, I; Matsumoto, A; Ohshiba, S; Okumura, Y; Takiuchi, H1
Hotta, K; Ishihara, K; Komuro, Y; Ohara, S; Ohkawa, H; Okabe, H1
Holm, L1
Blandizzi, C; Carignani, D; Del Tacca, M; Gherardi, G; Marveggio, C; Natale, G1
Alarcón de la Lastra, C; La Casa, C; Martín, MJ; Motilva, V1
Hotta, K; Ichikawa, T; Ishihara, K; Komuro, Y; Ohara, S1
Kamishiro, T; Masuda, M; Matsukura, H; Uchida, A1
DeBartolo, ML; Edmonds, AL; Gustavson, LE; Kaiser, JF; Locke, CS; Schneck, DW1
Holm, L; Synnerstad, I1
Alarcón de la Lastra, C; La Casa, M; López, A; Martin, MJ; Motilva, V1
Akiba, Y; Ishii, H; Nakamura, M; Oda, M1
Blandizzi, C; Carignani, D; Colucci, R; Del Tacca, M; Gherardi, G; Lazzeri, G; Marveggio, C; Natale, G1
Holm, L; Johansson, M; Synnerstad, I1
Brasil, DD; Brito, AR; de Almeida, AB; de Paula, AC; Gracioso, JD; Hiruma-Lima, CA; Muller, AH; Toma, W1
Cui, Z; Duan, Y; Li, Z; Liu, J; Nie, S; Xu, G; Zhan, X1
Sano, T; Urakami, Y1
Durham, S; McElhinney, C; Sarosiek, I; Sarosiek, J; Skoczylas, T; Sostarich, S1
Batista, LM; Calvo, TR; de Almeida, AB; de Pietro Magri, L; Souza Brito, AR; Toma, W; Vilegas, W1
Brotze, S; Connor, M; Jaworski, T; Roeser, K; Sarosiek, I; Sarosiek, J; Sostarich, S; Wallner, G1
Dharmani, P; Maurya, R; Mishra, PK; Palit, G; Singh Chauhan, V1
Hariprasath, L; Nanjian, R; Raman, J1
Abdelwahab, SI; Abdulla, MA; Ali, HM; Hadi, AH; Salga, MS; Taha, MM1
Abdelwahab, SI; Abdulla, MA; Al-Bayaty, FH; Ibrahim, IA; Nimir, AR; Qader, SW1
Hamid, HA; Hisam, EE; Mohtaruddin, N; Othman, F; Rofiee, MS; Zakaria, ZA1
AbuBakar, S; Appleton, D; Shu, MH; Zandi, K1
Amagase, K; Satoh, H; Takeuchi, K1

Reviews

1 review(s) available for omeprazole and guaifenesin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for omeprazole and guaifenesin

ArticleYear
Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Cross-Over Studies; Double-Blind Method; Drug Interactions; Gastric Acidity Determination; Gastric Mucosa; Humans; Male; Middle Aged; Mucus; Omeprazole; Stomach

1995
Significant enhancement of gastric mucin content after rabeprazole administration: its potential clinical significance in acid-related disorders.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Analysis of Variance; Benzimidazoles; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gastric Acidity Determination; Gastric Mucins; Gastric Mucosa; Humans; Male; Middle Aged; Mucus; Omeprazole; Probability; Rabeprazole; Reference Values; Sensitivity and Specificity

2003

Other Studies

26 other study(ies) available for omeprazole and guaifenesin

ArticleYear
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effects of anti-acid secretory agents on various types of gastric mucus.
    Journal of clinical gastroenterology, 1992, Volume: 14 Suppl 1

    Topics: Animals; Anti-Ulcer Agents; Gastric Juice; Gastric Mucosa; Hydrogen-Ion Concentration; Male; Mucus; Omeprazole; Pirenzepine; Prostaglandins E; Ranitidine; Rats

1992
Effect of the proton pump inhibitor, NC-1300, on gastric mucus secretion in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Gastric Mucosa; Glycoproteins; Hexoses; Ion Channels; Male; Mucus; Omeprazole; Protons; Rats; Rats, Inbred Strains

1989
Gastric mucosal blood flow and mucosal protection.
    Journal of clinical gastroenterology, 1988, Volume: 10 Suppl 1

    Topics: 16,16-Dimethylprostaglandin E2; Alprostadil; Animals; Dinoprostone; Gastric Mucosa; Male; Mucus; Neutrophils; Omeprazole; Rats; Rats, Inbred Strains

1988
Mechanisms of protection by omeprazole against experimental gastric mucosal damage in rats.
    Digestion, 1995, Volume: 56, Issue:3

    Topics: Animals; Ethanol; Gastric Acid; Gastric Mucosa; Gastritis; Hydrochloric Acid; Male; Misoprostol; Mucus; Necrosis; Omeprazole; Ranitidine; Rats; Rats, Wistar

1995
Antiulcerogenicity of the flavonoid fraction from Bidens aurea: comparison with ranitidine and omeprazole.
    Journal of ethnopharmacology, 1994, Volume: 42, Issue:3

    Topics: Acute Disease; Animals; Anti-Ulcer Agents; Cold Temperature; Disease Models, Animal; Female; Flavonoids; Gastric Mucosa; Glycoproteins; Male; Mucus; Omeprazole; Plant Extracts; Plants, Medicinal; Ranitidine; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer

1994
Effect on gastric mucus of the proton pump inhibitor leminoprazole and its cytoprotective action against ethanol-induced gastric injury in rats.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Cell Survival; Gastric Mucosa; Male; Mucins; Mucus; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1994
Effects of NC-1300-O-3 on gastric mucus secretion and prostaglandin release in rats.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Dinoprostone; Gastric Mucosa; Hexosamines; Hexoses; Indomethacin; Male; Mucus; Omeprazole; Prostaglandins; Rats; Rats, Sprague-Dawley

1994
Omeprazole induces high intraglandular pressure in the rat gastric mucosa.
    Gastroenterology, 1997, Volume: 112, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Injections, Intravenous; Intubation, Gastrointestinal; Male; Mucus; Omeprazole; Pentagastrin; Pharmaceutical Vehicles; Pressure; Rats; Rats, Inbred Lew; Rats, Inbred Strains

1997
Effects of cisapride on ulcer formation and gastric secretion in rats: comparison with ranitidine and omeprazol.
    General pharmacology, 1996, Volume: 27, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Cisapride; Gastric Juice; Gastric Mucosa; Histamine Release; Ligation; Male; Mucus; Omeprazole; Pepsin A; Piperidines; Ranitidine; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological

1996
Appearance of myofibroblasts in the gastric mucosa after ingestion of ethanol and lansoprazole with reevaluation of the mucoid cap.
    Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:S3 Pt 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Enzyme-Linked Immunosorbent Assay; Ethanol; Fibroblast Growth Factor 2; Fibroblasts; Gastric Mucosa; Lansoprazole; Male; Microscopy, Fluorescence; Mucus; Omeprazole; Rats; Rats, Wistar; Wound Healing

1998
Acid-independent gastroprotective effects of lansoprazole in experimental mucosal injury.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Ethanol; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Lansoprazole; Male; Mucus; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Wistar; Shock, Hemorrhagic

1999
Acid transport through channels in the mucous layer of rat stomach.
    Gastroenterology, 2000, Volume: 119, Issue:5

    Topics: Animals; Biological Transport; Coloring Agents; Congo Red; Gastric Acid; Gastric Mucosa; Hybridization, Genetic; Male; Mucus; Omeprazole; Pentagastrin; Rats; Rats, Inbred Strains

2000
Evaluation of the gastroprotective activity of cordatin, a diterpene isolated from Aparisthmium cordatum (Euphorbiaceae).
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Euphorbiaceae; Female; Gastric Acid; Gastric Juice; Gastric Mucosa; Lansoprazole; Male; Mice; Mucus; Omeprazole; Plant Extracts; Rats; Rats, Wistar; Stomach Ulcer; Trees

2000
[Changes of rat gastric mucosal barrier under stress conditions].
    Zhonghua nei ke za zhi, 2002, Volume: 41, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Bicarbonates; Gastric Acid; Gastric Mucosa; Male; Mucus; Omeprazole; Protons; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach Ulcer; Stress, Psychological

2002
Long-term follow-up of gastric metaplasia after eradication of Helicobacter pylori.
    The journal of medical investigation : JMI, 2003, Volume: 50, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Cicatrix; Convalescence; Drug Therapy, Combination; Duodenal Ulcer; Duodenoscopy; Female; Follow-Up Studies; Gastric Acid; Gastric Mucosa; Gastritis; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Lansoprazole; Male; Metaplasia; Metronidazole; Middle Aged; Mucus; Omeprazole; Severity of Illness Index

2003
Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Bethanechol; Cimetidine; Disease Models, Animal; Eriocaulaceae; Ethanol; Gastric Juice; Gastrointestinal Contents; Hydrogen-Ion Concentration; Indomethacin; Lansoprazole; Male; Mice; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological

2004
Restorative impact of rabeprazole on gastric mucus and mucin production impairment during naproxen administration: its potential clinical significance.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Exocrine Glands; Female; Gastric Juice; Gastric Mucins; Humans; Male; Middle Aged; Mucus; Naproxen; Omeprazole; Proton-Translocating ATPases; Rabeprazole

2005
Allophylus serratus: a plant with potential anti-ulcerogenic activity.
    Journal of ethnopharmacology, 2005, Jul-14, Volume: 99, Issue:3

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Male; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Sapindaceae; Solvents; Stomach Ulcer

2005
Gastroprotective effect of Senecio candicans DC on experimental ulcer models.
    Journal of ethnopharmacology, 2012, Mar-06, Volume: 140, Issue:1

    Topics: Adenosine Triphosphatases; Alkaloids; Animals; Anti-Ulcer Agents; Antioxidants; Biphenyl Compounds; Disease Models, Animal; Female; Flavonoids; Gastric Juice; Gastric Mucosa; India; Male; Mucus; Omeprazole; Picrates; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Senecio; Steroids; Stomach; Stomach Ulcer

2012
Gastroprotective activities of Turnera diffusa Willd. ex Schult. revisited: Role of arbutin.
    Journal of ethnopharmacology, 2012, May-07, Volume: 141, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Arbutin; Aspirin; Cell Line; Cytoprotection; Disease Models, Animal; Ethanol; Female; Gastric Acid; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Immunologic Factors; Interleukin-10; Interleukin-6; Lipid Peroxidation; Liver; Male; Mucus; Nitric Oxide; Omeprazole; Phytotherapy; Plant Extracts; Plants, Medicinal; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Turnera

2012
Effects of Pithecellobium jiringa ethanol extract against ethanol-induced gastric mucosal injuries in Sprague-Dawley rats.
    Molecules (Basel, Switzerland), 2012, Mar-06, Volume: 17, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Gastric Mucosa; Kidney; Lipid Peroxidation; Lipid-Linked Proteins; Liver; Male; Malondialdehyde; Mimosa; Mucus; Omeprazole; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Superoxide Dismutase

2012
Antiulcer activity of the chloroform extract of Bauhinia purpurea leaf.
    Pharmaceutical biology, 2012, Volume: 50, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Bauhinia; Chloroform; Chromatography, High Pressure Liquid; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Mucus; Omeprazole; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Solvents; Stomach Ulcer

2012
Anti-inflammatory, gastroprotective and anti-ulcerogenic effects of red algae Gracilaria changii (Gracilariales, Rhodophyta) extract.
    BMC complementary and alternative medicine, 2013, Mar-14, Volume: 13

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Betamethasone; Cell Line, Tumor; Chlorophyll; Dose-Response Relationship, Drug; Female; Gastric Juice; Gastric Mucosa; Gene Expression; Gracilaria; Humans; Hydrogen-Ion Concentration; Inflammation; Interleukin-6; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

2013
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:2

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Dose-Response Relationship, Drug; Gastric Mucins; Gastrointestinal Agents; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Misoprostol; Mucus; Omeprazole; Protective Agents; Proton Pump Inhibitors; Quinolones; Ranitidine; Rats; Rats, Wistar; Sus scrofa; Triazines

2014