omeprazole and cyclosporine

omeprazole has been researched along with cyclosporine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (16.67)	18.2507
2000's	11 (36.67)	29.6817
2010's	11 (36.67)	24.3611
2020's	3 (10.00)	2.80

Authors

Authors	Studies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Dai, R; Liu, Y; She, M; Wu, Z	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Clardy, J; Derbyshire, ER; Mota, MM; Prudêncio, M	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Mochizuki, T; Nemoto, R; Okabe, K; Satou, S	1
Meiser, BM; Muschiol, F; Nollert, G; Pfeiffer, M; Reichart, B; Reichenspurner, H; Uberfuhr, P; Vetter, HO; Wagner, F	1
Bonet, J; Caralps, A; Castellote, E; Cofan, F; Lauzurica, R; Pastor, C	1
Arranz, R; Fernández-Rañada, JM; Franceschi, JL; Yañez, E	1
Andersson, T; Blohmé, I; Idström, JP	1
Lorf, T; Ramadori, G; Ringe, B; Schwörer, H	2
Lorf, T; Ramadori, G; Ringe, B; Schwrer, H	1
Acevedo, A; Escudero, A; Fernández-Rañada, JM; Gil-Fernández, JJ; Martínez, E; Martínez-Chamorro, C	1
Bowrey, DJ; Jurewicz, WA; Logan, AJ; Morris-Stiff, GJ	1
Antonio Gil Ruiz, J; Barrio, J; Caro-Patón, A; Gil-Simón, P; Julián, L; Pérez-Miranda, M; Saracíbar, E	1
de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA	1
Chauhan, A; Muthuraman, A; Ramesh, M	1
Accassat, S; Basset, T; Bertoletti, L; Delavenne, X; Hodin, S; Mismetti, P; Ollier, E	1
Damanhuri, NS; Kumolosasi, E; Mansor, AH; Omar, MS; Razak, AFA	1

Reviews

3 review(s) available for omeprazole and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022
Acute necrotizing gastritis by Escherichia coli in a severely neutropenic patient. Haematologica, 2002, Volume: 87, Issue:1 Topics: Acute Disease; Amikacin; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Escherichia coli Infections; Gastric Mucosa; Gastritis; Granulocyte Colony-Stimulating Factor; Immunosuppressive Agents; Meropenem; Methylprednisolone; Necrosis; Neutropenia; Omeprazole; Parenteral Nutrition, Total; T-Lymphocytes; Thienamycins	2002

Trials

5 trial(s) available for omeprazole and cyclosporine

Article	Year
Changes of resorption and metabolism of cyclosporine after heart transplantation by the influence of gastrointestinal agents. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Administration, Oral; Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Antilymphocyte Serum; Azathioprine; Cimetidine; Cyclosporine; Drug Combinations; Famotidine; Female; Heart Transplantation; Humans; Intestinal Absorption; Magnesium Hydroxide; Male; Middle Aged; Omeprazole; Pirenzepine; Prednisone; Rats; Rats, Inbred BN	1994
A study of the interaction between omeprazole and cyclosporine in renal transplant patients. British journal of clinical pharmacology, 1993, Volume: 35, Issue:2 Topics: Adult; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Fluorescence Polarization; Humans; Kidney Transplantation; Male; Middle Aged; Omeprazole; Radioimmunoassay; Single-Blind Method	1993
Pantoprazole does not affect cyclosporin A blood concentration in kidney-transplant patients. European journal of clinical pharmacology, 2000, Volume: 55, Issue:10 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Cyclosporine; Enzyme Inhibitors; Female; Humans; Immunoassay; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Omeprazole; Pantoprazole; Prednisolone; Sulfoxides; Time Factors	2000
Upper gastrointestinal complications after renal transplantation: a 3-yr sequential study. Clinical transplantation, 2002, Volume: 16, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Child; Child, Preschool; Cyclosporine; Enzyme Inhibitors; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Omeprazole; Prospective Studies; Ranitidine; Tacrolimus; Treatment Outcome	2002
In vitro and in vivo evaluation of drug-drug interaction between dabigatran and proton pump inhibitors. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:6 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line, Tumor; Cyclosporine; Dabigatran; Drug Interactions; Humans; Lansoprazole; Male; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Thrombin; Young Adult	2015

Other Studies

22 other study(ies) available for omeprazole and cyclosporine

Article	Year
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors. Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3 Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 2012, May-29, Volume: 109, Issue:22 Topics: Animals; Anopheles; Antimalarials; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Inhibitory Concentration 50; Insect Vectors; Life Cycle Stages; Liver; Malaria; Malaria, Falciparum; Male; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Treatment Outcome	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Response of MBT-2 bladder carcinoma-induced osteolysis to various agents. Cancer, 1992, May-01, Volume: 69, Issue:9 Topics: Alendronate; Animals; Bone Neoplasms; Bone Resorption; Calcitonin; Cyclosporine; Diphosphonates; Female; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Omeprazole; Osteoclasts; Osteolysis; Urinary Bladder Neoplasms	1992
Does interaction between omeprazole and cyclosporin exist? Nephron, 1993, Volume: 65, Issue:3 Topics: Cyclosporine; Drug Interactions; Duodenal Ulcer; Humans; Kidney Transplantation; Male; Middle Aged; Omeprazole	1993
More about omeprazole-cyclosporine interaction. The American journal of gastroenterology, 1993, Volume: 88, Issue:1 Topics: Adult; Cyclosporine; Drug Interactions; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver; Omeprazole	1993
The effect of pantoprazole on tacrolimus and cyclosporin A blood concentration in transplant recipients. European journal of clinical pharmacology, 2000, Volume: 56, Issue:5 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Benzimidazoles; Cyclosporine; Enzyme Inhibitors; Enzyme Multiplied Immunoassay Technique; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Omeprazole; Organ Transplantation; Pantoprazole; Sulfoxides; Tacrolimus	2000
Pantoprazole and cyclosporine or tacrolimus. Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:4 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Immunosuppressive Agents; Liver; Mixed Function Oxygenases; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Sulfoxides; Tacrolimus	2001
[Esophageal Crohn's disease]. Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:2 Topics: Adrenal Cortex Hormones; Adult; Algorithms; Anti-Ulcer Agents; Crohn Disease; Cyclosporine; Endoscopy, Digestive System; Esophagitis; Female; Humans; Immunologic Factors; Immunosuppressive Agents; Middle Aged; Omeprazole; Prednisone; Tumor Necrosis Factor-alpha	2008
Tuberculosis in a patient on temozolomide: a case report. Journal of neuro-oncology, 2009, Volume: 92, Issue:1 Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary	2009
Mitochondrial dependent apoptosis: ameliorative effect of flunarizine on ischemia-reperfusion of celiac artery-induced gastric lesions in the rat. Digestive diseases and sciences, 2011, Volume: 56, Issue:8 Topics: Animals; Anti-Ulcer Agents; Apoptosis; Calcium; Celiac Artery; Cyclosporine; Flunarizine; Glutathione; Immunosuppressive Agents; Male; Mitochondria; Omeprazole; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Stomach; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vasodilator Agents	2011
The influence of P-glycoprotein expression in the standard treatment of Helicobacter pylori infection in Sprague Dawley rats. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2021, Volume: 29, Issue:1 Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cyclosporine; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Male; Omeprazole; Proton Pump Inhibitors; Rats, Sprague-Dawley; Rifampin; Stomach Ulcer	2021