omeprazole and cimetidine

omeprazole has been researched along with cimetidine in 280 studies

Research

Studies (280)

TimeframeStudies, this research(%)All Research%
pre-199090 (32.14)18.7374
1990's118 (42.14)18.2507
2000's53 (18.93)29.6817
2010's17 (6.07)24.3611
2020's2 (0.71)2.80

Authors

AuthorsStudies
Hajos, ZG; Press, JB; Sanfilippo, PJ; Scott, CK; Shriver, DA; Urbanski, M1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Pratim Roy, P; Roy, K1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dajani, EZ; Ives, MM; Larsen, KR1
Mosbech, J; Møller, H; Nissen, A1
Arakawa, T; Dajani, EZ; Kobayashi, K1
Arisawa, T; Asai, J; Goto, H; Hase, S; Suzuki, T; Tsukamoto, Y1
Joelson, IB; Joelson, S; Lundborg, P; Walan, A; Wallander, MA1
Harasawa, S; Matsumoto, M; Miwa, T; Morita, R1
Franzin, F; Lunazzi, G; Moretti, M; Pozzato, G; Stebel, M1
Gardner, JD; Jensen, RT; Maton, PN; Metz, DC; Norton, JA; Pisegna, JR; Slimak, GG1
Andersson, T; Boström, H; Jones, AW; Jönsson, KA1
Bardhan, KD; Bianchi Porro, G; Carroll, NJ; Daly, MJ; Hinchliffe, RF; Lazzaroni, M; Morris, P; Naesdal, J; Petrillo, M; Thompson, M1
Guram, M; Holt, S; Howden, CW1
Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y1
Koop, H1
Bright, RM; DeNovo, RC; Jenkins, CC; Patton, CS; Rohrbach, BW1
Goto, H; Hase, S; Mizutani, K; Nakamura, T; Nakazawa, S; Niwa, Y; Ohashi, S; Tsukamoto, Y; Yoshikane, H; Yoshino, J1
Eastwood, GL; Kuwayama, H; Matsuo, Y1
Chen, BW; Cho, CH; Hui, WM; Lam, SK; Luk, CT1
Bradstreet, DC; Simon, TJ1
Belaïche, J1
Diébold, MD; Duchateau, A; Thiéfin, G; Zeitoun, P1
Cerf, M1
Fryklund, J; Wallmark, B1
Eriksson, S; Helander, HF; Helander, KG; Rutgersson, K; Simonsson, M; Sundler, F1
Gönne, S; Kromer, W; Postius, S; Riedel, R1
Hurwitz, A; Parkinson, A1
Fryklund, J; Gedda, K; Sachs, G; Scott, D; Wallmark, B1
Eckersall, PD; McKellar, QA; Mostofa, M1
Barber, JH; Davis, RH; Freeling, P; Peers, EM; Richardson, PD; Stott, NC1
Carroll, NJ; Colin-Jones, D; Dehn, TC; Kettlewell, MG; Shepherd, HA1
Bate, CM; Davis, M; Foster, DN; Harvey, RF; Keeling, PW; Mountford, RA; O'Morain, C; Temperley, JM; Thompson, DG; Wilkinson, SP1
Arvidsson, S; Carter, K; Ito, S; Silen, W; Yanaka, A1
Rowbotham, DJ1
Andersson, T; Andrén, K; Cederberg, C; Edvardsson, G; Heggelund, A; Lundborg, P1
Plas, J1
Bardhan, KD; Carroll, NJ; Daly, MJ; Dhande, DS; Hinchliffe, RF; Jones, RB; Morris, P; Thompson, M1
Bar-Meir, S; Bruck, R; Krepel, Z1
Black, JW; Shankley, NP1
Ballantyne, GH; Cambria, RP; Modlin, IM; Schafer, DE; Tyshkov, M; Zdon, MJ1
Harasawa, S; Konagaya, M; Matsumoto, M; Miwa, T1
Atthapaisalsarudee, C; Kurathong, S; Leethochawalit, M; Saowaros, V; Wilairatana, S1
Bate, CM; Crowe, JP; Peers, EM; Richardson, PD; Wilkinson, SP; Willoughby, CP1
Celle, G; Mela, GS; Savarino, V1
Banerjee, RK; Bhattacharjee, M; Bose, AK1
Bianchi Porro, G; Parente, F1
Amoruso, A; Barone, M; Di Leo, A; Francavilla, A; Ingrosso, M; Makowka, L; Panella, C; Polimeno, L; Starzl, TE1
de Bruijne, JW; Lamers, CB1
De Natale, F; De Natale, G; Marino, A1
Bardram, L; Stadil, F1
Gardner, JD; Jensen, RT; Maton, PN1
Debas, HT; Mulholland, MW1
Delchier, JC; Eriksson, S; Isal, JP; Soule, JC1
Bate, CM; Bateson, MC; Bradby, GV; Crowe, JP; Hislop, WS; Peers, EM; Richardson, PD; Wilkinson, SP; Willoughby, CP1
Sölvell, L1
Lauritsen, K1
Classen, M; Schepp, W1
de Bruijne, JW; Lamers, CB; Snel, P1
Niida, H; Okabe, S; Okada, M; Takeuchi, K1
Arisawa, T; Asai, J; Nakazawa, S; Tsukamoto, Y1
Cook, PG; Mangel, AW; Pendleton, RG; Shepherd-Rose, A1
Guslandi, M1
Bader, JP; Cortot, A; Delchier, JC; Goldfain, D; Isal, JP; Mignon, M; Soule, JC; Travers, B1
De Graef, J; Woussen-Colle, MC1
Katsuyama, Y; Watanabe, K; Yano, S1
Mahachai, V; Thomson, AB1
Nio, CY; Tytgat, GN1
Fernández, AG; Massingham, R; Roberts, DJ1
De Graef, J; Simoens, C; Woussen-Colle, MC1
Daneshmend, TK; Walt, RP1
Pounder, R1
Duchateau, A; Thiefin, G; Varin-Bischoff, S; Zeitoun, P1
Carlsson, E; Ives, MM; Jensen, NF; Larsen, KR; Larsson, H1
Brunkwall, J; Dahlgren, S; Domellöf, L; Gasslander, T; Hradsky, M; Karlsson, J; Knutson, U; Norryd, C; Svensson, G; Svensson, JO1
Larsson, H; Lorentzon, P; Wallmark, B1
Elander, B; Fellenius, E; Leth, R; Olbe, L; Wallmark, B1
Wallmark, B1
Honda, N; Kaneko, E; Kumagai, J; Oka, H1
Carrasquer, G; Rehm, WS; Schwartz, M1
Dammann, HG; Kommerell, B; Müller, P; Simon, B1
Gilbertson, SK; Kolbasa, KP; Lancaster, C; Olafsson, AS; Robert, A1
Nishiwaki, H; Okabe, S; Takeuchi, K1
Namba, S1
Poulsen, SS; Skov Olsen, P; Therkelsen, K1
Gönne, S; Kromer, W1
Ayrton, A; Chenery, RJ; Norman, SJ; Oldham, HG; Standring, P1
Carrasquer, G; Dinno, MA; Rehm, WS; Schwartz, M1
Astrup, L; Bendtsen, F; Bytzer, P; Havelund, T; Lauritsen, K; Laursen, LS; Linde, J; Olsen, JH; Rune, SJ; Wulff, HR1
Batzri, S; Dubois, A; Harmon, JW; Moskowitz, D; Rich, NM; Weichbrod, R1
Bader, JP; Bigard, MA; Ebrard, F; Galmiche, JP; Isal, JP1
Karasawa, H; Miwa, T; Tani, N1
Archambault, AP; Bailey, RJ; Baker, SJ; Freeman, HJ; Hunt, RH; Marcon, NE; Navert, H; Pare, P; Sutherland, L; Williams, CN1
Guth, PH; Leung, FW; Livingston, E; Pique, JM; Scremin, OU; Tan, HW1
Bonnin, M; Hetzel, DJ1
Larsson, H; Mattsson, H1
Brodin, K; Elwin, CE; Goiny, M; Uvnäs-Moberg, K1
Furukawa, O; Nishiwaki, H; Okabe, S; Takeuchi, K1
Jourdan, MH; Mason, RC; Rowe, PH1
Kirkegaard, P; Poulsen, SS; Raaberg, L; Skov Olsen, P; Therkelsen, K1
Brent, PJ; Dosen, PJ; Gerkens, JF; Henry, DA1
Burget, DW; Howden, CW; Hunt, RH; Jones, DB1
Andersen, HH; Bendtsen, F; Bytzer, P; Højlund, M; Jensen, KG; Kelbaek, H; Lauritsen, K; Linde, J; Rask-Madsen, J; Rune, SJ1
Deveney, CW; Deveney, KE1
Spenney, JG1
Spiro, HM1
Carter, DC; Salim, AS; Utley, RJ1
Bar-Meir, S; Jedwab, M; Missri, A; Sehayek, E1
Gustavsson, S; Mårdh, S; Norberg, L; Nyrén, O; Wollert, S1
Misiewicz, JJ1
Blum, AL; Fimmel, CJ1
Jansen, JB; Lambers, CB; Lind, T; Moberg, S; Olbe, L1
Demling, L1
Jones, DB; Smallwood, RA; Webster, LK1
Levine, JB1
Berglindh, T; Elander, B; Fellenius, E; Olbe, L; Sachs, G; Sjöstrand, SE; Wallmark, B1
Brändström, A; Fellenius, E; Jaresten, BM; Larsson, H; Ryberg, B; Wallmark, B1
Fryklund, J; Helander, HF; Larsson, H; Wallmark, B1
Becker, HD1
Carlsson, E; Larsson, H; Sundell, G1
Pounder, RE1
Helander, HF; Sundell, GW1
Hetzel, DJ; Shearman, DJ1
Dammann, HG; Müller, P; Simon, B; Walter, TA1
Helander, HF1
Carlsson, E; Junggren, U; Larsson, H; Olbe, L; Sjöstrand, SE; Skånberg, I; Sundell, G1
Battiston, L; Marchi, P; Mazzoran, L; Moretti, M; Pozzato, G; Pussini, E; Tulissi, P1
Castell, DO; Just, RJ; Lagerström, PO; Leite, LP1
Aoyama, N; Chiba, T; Himeno, S; Kasuga, M; Kinoshita, Y; Misaki, F1
Hirano, M; Oka, H; Sakurabayashi, S; Sezai, S; Yamamoto, Y1
Carlsson, R; Eriksson, S; Långström, G; Naesdal, J; Rikner, L1
Amemiya, T; Fujimura, M; Matsuda, T; Mizuguchi, M; Nishi, K; Ooka, T1
Kamato, T; Miyata, K; Nishida, A; Ohta, M; Shikama, H; Yanagisawa, I; Yuki, H1
Piper, DW1
Beil, W; Bokemeyer, C; Mai, UE; Manns, MP; Meyer, HJ; Wagner, S1
Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T1
Inaguma, K; Ito, M; Segami, T; Suzuki, Y1
Bachmann, KA; Jauregui, L; Levine, L; Miller, K; Reese, J; Sullivan, TJ1
Bajador, E; Gomollón, F; Sebastián, JJ; Simón, MA; Uribarrena, R1
Okabe, S; Tsukimi, Y1
Chen, SH; Liao, CH; Lien, GS; Pan, S1
Degtiareva, II; Egorova, IT; Gaĭsenko, AV; Kharchenko, NV; Petrovich, S; Semeunovich, S1
Fujihara, A; Kamato, T; Miyata, K; Nishida, A; Takeda, M; Yuki, H1
Besancon, M; Helander, H; Sachs, G; Scott, DR1
Meiser, BM; Muschiol, F; Nollert, G; Pfeiffer, M; Reichart, B; Reichenspurner, H; Uberfuhr, P; Vetter, HO; Wagner, F1
Fujii, T; Kato, S; Naganuma, H; Nakagawa, H; Nakano, K1
Kamishiro, T; Masuda, M; Matsukura, H; Uchida, A1
Galmiche, JP; Le Rhun, M1
James, OF; Parry-Billings, KS1
Havelund, T; Lauritsen, K; Laursen, LS1
Jones, AW; Jönsson, KA1
Abe, K; Furukawa, Y; Katano, K; Mizunashi, K1
Bhasin, DK; Khosla, PP; Sachdev, A; Saha, N; Sankaranahyanan, A; Sharma, PL; Singh, K1
Davis, RL; Egli, D; Hashimoto, F1
Car, D; Cvitanović, B; Dubracić, D; Georgijević, A; Katicić, M; Pulanić, R1
García Rodríguez, LA; Jick, H1
Bruno, MJ; Hoek, FJ; Rauws, EA; Tytgat, GN1
Abad, MJ; Acosta, A; Michelangeli, F; Ruiz, MC1
Bei, L; Chen, SP; Wen, SH1
Hassall, E1
Celle, G; Cutela, P; Dallorto, E; Franceschi, M; Mansi, C; Mela, GS; Mela, MR; Savarino, V; Vassallo, A; Zentilin, P1
Marks, RD; Richter, JE1
Malfertheiner, P1
Kato, S; Okabe, S; Takeuchi, K1
Bouly, A; Feiss, P; Nathan, N1
Papich, MG1
Charrasse, S; Daujat, M; Fabre, I; Jounaïdi, Y; Larroque, C; Lesca, P; Maurel, P; Poellinger, L1
Bischof, G; Feil, W; Riegler, M; Schiessel, R; Wenzl, E1
Ito, M; Segami, T; Suzuki, Y1
Dial, EJ; Illich, PA; Lichtenberger, LM; Romero, JJ; Ulloa, C; Vanous, AL1
Chakrabarti, A; Goenka, MK; Gupta, O; Kochhar, R; Kumar, A; Mehta, SK; Talwar, P1
Bochner, F; Reinhard, HA; Somogyi, AA1
Bille, J; Blum, AL; Duroux, P; Fried, M; Froehlich, F; Gonvers, JJ; Gyr, K; Nicolet, M; Pignatelli, B; Saraga, E; Schwizer, W; Thorens, J1
Cronhjort, M; Garmelius, B; Jacobsson, H; Jonsson, C; Nilsson, SO1
Coffey, RJ; Greenson, JK; Meise, KS; Scheiman, JM1
Berstad, A; Hatlebakk, JG1
Buljat, G; Gjurasin, M; Grabarević, Z; Hanzevacki, M; Jadrijević, S; Jagić, V; Jelovac, N; Jurina, L; Konjevoda, P; Marović, A; Miklić, P; Mikus, D; Mise, S; Perić, J; Perović, D; Petek, M; Rotkvić, I; Rucman, R; Seiwerth, S; Separović, J; Sikirić, P; Turković, B; Zoricić, I1
Ballesta, A; Gómez, F; Ortiz, JA; Romero, A; Sacristán, A; Villamayor, F1
Axon, AT; Bate, CM; Emmas, CE; Green, JR; Murray, FE; Taylor, MD; Tildesley, G1
Itoh, T; Kamisaki, Y; Kawasaki, H; Kishimoto, Y; Kitano, M; Nakamoto, K; Wada, K1
Blohmé, I; Mjörnstedt, L; Olausson, M; Wramner, L1
Jick, H; Meier, CR1
Florholmen, J; Løvhaug, N; Støa-Birketvedt, G; Vonen, B1
Lee, FY; Lin, HJ; Lo, WC; Perng, CL; Tseng, GY1
Battiston, L; Moretti, M; Pozzato, G; Tulissi, P1
Ashida, K; Itoh, T; Kamisaki, Y; Kawasaki, H; Kishimoto, Y; Kitano, M; Nakamoto, K; Wada, K1
Alliët, P; Bruneel, E; Gillis, P; Raes, M1
Bardhan, KD; Bishop, A; Brooks, A; Cherian, P; D'Silva, J; Gillon, KR; Jones, RB; Manek, S; Morris, P; Parkin, S; Patterson, J; Polak, J; Thompson, M; Vaishnavi, A1
Field, SK; Sutherland, LR1
Brown, AS; James, OF1
Axon, AT; Bate, CM; Emmas, C; Green, JR; Murrays, FE; Owen, SM; Taylor, MD; Tildesley, G1
Fujimura, A; Maeda, A; Sasaki, M1
Ishihara, M; Ito, M; Suzuki, Y1
Bamba, T; Nakajima, S1
Akagi, K; Hasebe, K; Nagao, T; Urushidani, T; Watanabe, K1
Chan, CK; Cheung, E; Ching, TY; Chu, KM; Kong, Y; Kou, M; Kumana, CR; Lam, SK; Seto, WH1
Fukuda, S; Haga, Y; Mikami, T; Munakata, A; Murata, Y; Shimoyama, T; Tanaka, M; Yamagata, R; Yoshimura, T1
Bate, CM; Richardson, PD1
Cuddihy, PJ; Griffith, H; Maheshwar, A1
García Rodríguez, LA; Ruigómez, A1
Arakawa, T; Higuchi, K; Kobayashi, K; Kuroki, T; Takaishi, O; Yamasaki, K1
Arita, M; Hatakeyama, S; Imamura, T; Matsui, T; Motomura, A; Okada, M; Takeyama, Y; Tanaka, K; Yao, T1
Agostinis, L; Cattaruzzi, C; García Rodríguez, LA; Johansson, S; Ruigómez, A; Troncon, MG; Wallander, MA1
Eloubeidi, M; Rockey, DC1
Chen, J; Chen, SY; Wang, JY; Zhang, SS; Zhang, XD1
Butters, CJ; McKillop, D; Wild, MJ1
Lamers, CB1
Dai, S; Jia, L; Li, Y; Nie, Y; Sha, W; She, Q; Wu, H; Yu, W1
Abbas, R; Bramer, SL; Browder, NJ; Chow, CP; Flockhart, DA; Forbes, W; Fu, CJ; Odomi, M; Thacker, D1
Hagen, SJ; Morrison, SW; Wu, H1
Grime, J; Pollock, K1
Dillon, JF; Johnston, DA; MacDonald, TM; Todd, JA; Weston, T1
Anic, T; Aralica, G; Bilic, I; Buljat, G; Ivankovic, D; Mikus, D; Mise, S; Perovic, D; Petek, M; Prkacin, I; Rotkvic, I; Rucman, R; Seiwerth, S; Separovic, J; Sikiric, P; Stancic-Rokotov, D; Zoricic, I1
Almeida, AB; Brasil, DS; Gracioso, JS; Hiruma-Lima, CA; Muller, AH; Paula, AC; Souza Brito, AR; Toma, W1
Furuta, S; Kamada, E; Kawabata, Y; Sano, H; Shinozaki, Y; Sugimoto, T; Suzuki, T1
Caroppo, R; Geibel, JP; Gloeckner, J; Kirchhoff, P; Manuelidis, L; Qureshi, I; Radebold, K; Wagner, CA1
Buskens, E; de Wit, NJ; Lewin van den Broek, NT; Numans, ME; Smout, AJ; Verheij, TJ1
Akao, T; He, JX; Nishino, T; Tani, T1
Page, RL; Ruscin, JM; Valuck, RJ1
Di Stasi, LC; Gonzalez, FG1
Ishihara, M; Ito, M1
Lewis, JD; Yang, YX1
Huggins, RM; Latour, JK; Scates, AC1
Czuprynski, CJ; Faith, NG; Neudeck, B; Steinberg, H1
Ermolaev, IA; Nazarov, VE; Rukhliada, NV1
Chu, CH; Hsu, TC; Huang, PC; Leu, SC; Su, CF; Wang, TE1
Cury, EK; Faintuch, S; Schraibman, V1
Batista, LM; Calvo, TR; de Almeida, AB; de Pietro Magri, L; Souza Brito, AR; Toma, W; Vilegas, W1
Kinoshita, E; Mukai, S; Ohtani, H; Sawada, Y; Yamaguchi, T1
Bernsand, M; Haenuki, Y; Håkanson, R; Hasegawa, J; Kishimoto, Y; Kitano, M; Kudo, M; Norlén, P1
Lemahieu, WP; Maes, BD; Vanrenterghem, Y; Verbeke, K1
Isakov, VA; Ivanova, OV; Paleev, NR1
Black, WD; Chan, DY; Hale, BA; Waisberg, M1
Fujimura, M; Hara, J; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Oribe, Y1
Bagin, RG; Conrad, SA; Frank, WO; Gabrielli, A; Hata, JS; Hepburn, B; Laine, L; Margolis, B; Quartin, A; Rock, JA1
Busque, SM; Geibel, JP; Insogna, K; Kerstetter, JE1
Malling, D; Poulsen, MN; Søgaard, B1
Cho, HY; Lee, YB; Park, EJ1
Busque, SM; Dave, MH; Dufner, M; Geibel, JP; Kirchhoff, P; Kosiek, O; Remy, C; Verrey, F; Wagner, CA1
Fattahi, E; Khaleghian, F; Khoshbaten, M; Naderi, N; Rezailashkajani, M1
Cheng, YC; Lin, HJ; Lo, WC; Perng, CL1
Dube, PH; Handley, SA; Miller, VL1
Cunha-Melo, JR; da Conceição, SA; da Luz, MM; de Araújo, GK; Lisboa, FA; Melo, JR; Moraes-Santos, T1
Esplugues, JV; Martí-Cabrera, M; Ponce, J1
Amagase, K; Kobata, A; Kotani, T; Murashima, Y; Takeuchi, K1
Bastos, JK; da Silva Filho, AA; de Andrade, SF; de Barros, MP; Lemos, M; Sousa, JP1
Comunello, E; de Andrade, SF; Filho, VC; Lemos, M; Niero, R; Noldin, VF1
Elke, G; Schädler, D; Scholz, J; Weiler, N; Zick, G1
Campbell, CA; Chiu, P; Darton, J; Gaskin, PJ; Lee, K; McLean, PG1
Andrade, SF; Becker, RG; Berté, TE; Cechinel-Filho, V; Delle-Monache, F; Meyre-Silva, C; Petry, CM; Zanatta, F1
Chang, CH; Hsu, PI; Huang, YB; Lin, PC; Tseng, PL1
Amagase, K; Kato, S; Ochi, A; Sugihara, T; Takeuchi, K1
Miller, GP1
Eberlein, B; Gebhardt, E; Gilbertz, KP; Placzek, M; Przybilla, B1
Czimmer, J; Mózsik, G; Szabó, IL; Szolcsányi, J1
Fei, Z; Gao, DK; Hu, SJ; Li, B; Lin, W; Liu, BL; Zhang, L; Zhang, X1
Arthur, RM; Knych, HK; McKemie, DS; Stanley, SD1
Brockmöller, S; Steinritz, D; Thiermann, H; Tsoutsoulopoulos, A1
Hongo, M; Hunt, RH; Lazarescu, A; Lottrup, C; Scarpignato, C; Stein, E; Wu, JCY1

Reviews

42 review(s) available for omeprazole and cimetidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Refractory peptic ulcers.
    Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 1992, Volume: 3, Issue:3

    Topics: Anti-Ulcer Agents; Chronic Disease; Cimetidine; Gastric Mucosa; Humans; Meta-Analysis as Topic; Omeprazole; Peptic Ulcer

1992
Safety experience from long-term treatment with omeprazole.
    Digestion, 1992, Volume: 51 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Clinical Trials as Topic; Esophagitis, Peptic; Female; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Ranitidine

1992
[New developments in drug therapy: omeprazole].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1991, Volume: 26

    Topics: Cimetidine; Duodenal Ulcer; Humans; Omeprazole; Ranitidine; Smoking; Stomach Ulcer

1991
[Effects of gastric acid secretion inhibition on intrinsic factor secretion and cobalamin absorption].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5 ( Pt 2)

    Topics: Absorption; Cimetidine; Duodenal Ulcer; Gastrectomy; Gastric Acid; Gastritis, Atrophic; Humans; Intrinsic Factor; Omeprazole; Ranitidine; Reference Values; Vitamin B 12

1991
[Effects of antisecretory therapy on serum gastrin and argyrophil cells of the fundus mucosa].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5 ( Pt 2)

    Topics: Cimetidine; Duodenal Ulcer; Esophagitis; Gastric Mucosa; Gastrins; Humans; Omeprazole; Ranitidine; Vagotomy, Proximal Gastric

1991
[Gastric anacidity. Effects on gastrointestinal microflora and physiopathological consequences].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5 ( Pt 2)

    Topics: Bacteria, Aerobic; Bacteria, Anaerobic; Cimetidine; Gastric Acid; Humans; Ileum; Jejunum; Nitrate Reductases; Omeprazole; Ranitidine; Stomach

1991
Omeprazole and the induction of human cytochrome P-450: a response to concerns about potential adverse effects.
    Gastroenterology, 1991, Volume: 100, Issue:4

    Topics: Acetaminophen; Carcinogens; Cimetidine; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Humans; Omeprazole; Phenacetin

1991
Omeprazole in the treatment of duodenal ulcer.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Adenosine Triphosphatases; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; H(+)-K(+)-Exchanging ATPase; Humans; Omeprazole; Parietal Cells, Gastric; Ranitidine

1989
[Is strong inhibition of gastric acid in the treatment of peptic ulcer sensible?].
    Nederlands tijdschrift voor geneeskunde, 1989, Apr-01, Volume: 133, Issue:13

    Topics: Cimetidine; Clinical Trials as Topic; Double-Blind Method; Gastric Acid; Histamine H2 Antagonists; Humans; Omeprazole; Peptic Ulcer; Random Allocation; Ranitidine

1989
[Drugs used in the therapy of peptic ulcer with special reference to H2 receptor blockaders].
    La Clinica terapeutica, 1989, Apr-15, Volume: 129, Issue:1

    Topics: Antacids; Anti-Ulcer Agents; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Omeprazole; Peptic Ulcer; Pirenzepine; Ranitidine; Thiazoles

1989
Recent advances in the management of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome.
    Gastroenterology clinics of North America, 1989, Volume: 18, Issue:4

    Topics: Cimetidine; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans; Nizatidine; Omeprazole; Parasympatholytics; Ranitidine; Thiazoles; Zollinger-Ellison Syndrome

1989
Drug therapy in peptic ulcer disease.
    Current problems in surgery, 1989, Volume: 26, Issue:1

    Topics: Cimetidine; Histamine Antagonists; Humans; Omeprazole; Peptic Ulcer; Pirenzepine; Prostaglandins; Ranitidine

1989
Omeprazole in the acute treatment of gastric ulcer.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Cimetidine; Clinical Trials as Topic; Humans; Omeprazole; Ranitidine; Stomach Ulcer; Wound Healing

1989
Efficacy of the H+/K+-adenosine triphosphatase inhibitor omeprazole in peptic ulcer.
    Digestion, 1989, Volume: 44 Suppl 1

    Topics: Cimetidine; Duodenal Ulcer; Humans; Omeprazole; Ranitidine; Stomach Ulcer; Therapeutic Equivalency

1989
Ulcer-healing drugs and endogenous prostaglandins.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:8

    Topics: Aluminum; Animals; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Carbenoxolone; Cimetidine; Gastric Acid; Humans; Omeprazole; Peptic Ulcer; Pirenzepine; Prostaglandins; Ranitidine; Somatostatin; Stimulation, Chemical; Sucralfate

1985
Pharmacological management of patients with peptic ulcer disease: prospects for the late 1980's.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1987, Volume: 10, Issue:3

    Topics: Alprostadil; Antacids; Anti-Ulcer Agents; Cimetidine; Drug Resistance; Enprostil; Famotidine; Histamine H2 Antagonists; Humans; Misoprostol; Omeprazole; Peptic Ulcer; Pirenzepine; Prostaglandins; Prostaglandins E, Synthetic; Ranitidine; Sucralfate; Thiazoles

1987
The medical therapy of reflux oesophagitis.
    Bailliere's clinical gastroenterology, 1987, Volume: 1, Issue:4

    Topics: Antacids; Bethanechol; Bethanechol Compounds; Cimetidine; Cisapride; Domperidone; Esophagitis, Peptic; Gastroesophageal Reflux; Humans; Metoclopramide; Omeprazole; Piperidines; Ranitidine; Sucralfate

1987
Medical treatment of peptic ulcers.
    Surgery annual, 1985, Volume: 17

    Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzimidazoles; Bismuth; Cimetidine; Humans; Omeprazole; Parasympatholytics; Peptic Ulcer; Prostaglandins; Ranitidine; Recurrence; Sucralfate; Zollinger-Ellison Syndrome

1985
Treatment of ulcer disease.
    The Alabama journal of medical sciences, 1985, Volume: 22, Issue:1

    Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Clinical Trials as Topic; Gastric Acid; Humans; Omeprazole; Peptic Ulcer; Ranitidine; Sucralfate

1985
Medical management of peptic ulcer.
    Postgraduate medical journal, 1984, Volume: 60, Issue:709

    Topics: Aluminum; Antacids; Benzimidazoles; Bismuth; Carbenoxolone; Cimetidine; Duodenal Ulcer; Humans; Omeprazole; Parasympatholytics; Ranitidine; Recurrence; Stomach Ulcer; Sucralfate; Time Factors

1984
Pharmacologic options for the control of peptic ulcer disease.
    Advances in internal medicine, 1984, Volume: 30

    Topics: Antacids; Anti-Ulcer Agents; Benzimidazoles; Bismuth; Carbenoxolone; Cimetidine; Duodenal Ulcer; Histamine H2 Antagonists; Humans; Omeprazole; Parasympatholytics; Peptic Ulcer; Prostaglandins, Synthetic; Ranitidine; Risk; Stomach Neoplasms; Surface-Active Agents

1984
[Zollinger-Ellison syndrome].
    Wiener klinische Wochenschrift, 1984, Feb-17, Volume: 96, Issue:4

    Topics: Benzimidazoles; Calcium; Cimetidine; Diarrhea; Duodenal Ulcer; Female; Fluorouracil; Gastrectomy; Gastric Acid; Gastrins; Glucagon; Humans; Male; Middle Aged; Omeprazole; Pancreatic Neoplasms; Prognosis; Ranitidine; Secretin; Streptozocin; Zollinger-Ellison Syndrome

1984
Omeprazole and H2-receptor antagonists in the acute treatment of duodenal ulcer, gastric ulcer and reflux oesophagitis: a meta-analysis.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:5

    Topics: Adult; Cimetidine; Double-Blind Method; Duodenal Ulcer; Esophagitis, Peptic; Female; Humans; Male; Middle Aged; Omeprazole; Randomized Controlled Trials as Topic; Ranitidine; Reproducibility of Results; Stomach Ulcer; Time Factors; Wound Healing

1995
A comparative overview of the adverse effects of antiulcer drugs.
    Drug safety, 1995, Volume: 12, Issue:2

    Topics: Antacids; Anti-Ulcer Agents; Carcinoid Tumor; Cimetidine; Humans; Misoprostol; Omeprazole; Ranitidine; Sucralfate

1995
[Is remission of Barrett esophagus possible?].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:1 Pt 2

    Topics: Antacids; Barrett Esophagus; Bethanechol Compounds; Cimetidine; Drug Therapy, Combination; Gastroesophageal Reflux; Humans; Omeprazole; Remission Induction; Retinoids

1994
Efficacy of omeprazole in lower grades of gastro-oesophageal reflux disease.
    Scandinavian journal of gastroenterology. Supplement, 1994, Volume: 201

    Topics: Cimetidine; Clinical Trials as Topic; Double-Blind Method; Gastroesophageal Reflux; Humans; Omeprazole; Ranitidine

1994
Barrett's esophagus: new definitions and approaches in children.
    Journal of pediatric gastroenterology and nutrition, 1993, Volume: 16, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Barrett Esophagus; Child; Child, Preschool; Cimetidine; Endoscopy, Gastrointestinal; Esophageal Neoplasms; Esophagus; Female; Gastroesophageal Reflux; Humans; Infant; Male; Middle Aged; Omeprazole; Precancerous Conditions

1993
Peptic strictures of the esophagus.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:8

    Topics: Behavior Therapy; Causality; Cimetidine; Diagnosis, Differential; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Humans; Omeprazole

1993
Compliance, adverse events and antibiotic resistance in Helicobacter pylori treatment.
    Scandinavian journal of gastroenterology. Supplement, 1993, Volume: 196

    Topics: Amoxicillin; Bismuth; Cimetidine; Drug Resistance, Microbial; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Patient Compliance; Peptic Ulcer; Tinidazole

1993
Antiulcer therapy.
    The Veterinary clinics of North America. Small animal practice, 1993, Volume: 23, Issue:3

    Topics: Animals; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cats; Cimetidine; Dogs; Gastrointestinal Diseases; Histamine Agonists; Horses; Humans; Omeprazole; Prostaglandins, Synthetic; Rats; Sucralfate; Treatment Outcome; Ulcer

1993
Pharmacokinetic optimisation in the treatment of gastro-oesophageal reflux disease.
    Clinical pharmacokinetics, 1996, Volume: 31, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Benzimidazoles; Cimetidine; Cisapride; Domperidone; Famotidine; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Lansoprazole; Metoclopramide; Nizatidine; Omeprazole; Pantoprazole; Piperidines; Proton Pump Inhibitors; Ranitidine; Sucralfate; Sulfoxides

1996
Does medical antireflux therapy improve asthma in asthmatics with gastroesophageal reflux?: a critical review of the literature.
    Chest, 1998, Volume: 114, Issue:1

    Topics: Antacids; Anti-Asthmatic Agents; Anti-Ulcer Agents; Asthma; Cimetidine; Circadian Rhythm; Cisapride; Gastroesophageal Reflux; Humans; Lung; Omeprazole; Peak Expiratory Flow Rate; Piperidines; Placebos; Randomized Controlled Trials as Topic; Ranitidine; Spirometry

1998
[Recent progress in the drug therapy for gastrointestinal bleeding].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:9

    Topics: Anti-Ulcer Agents; Cimetidine; Gastric Acidity Determination; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Muscarinic Antagonists; Omeprazole; Pirenzepine; Proton Pump Inhibitors

1998
[25 years of gastric acid blockers].
    Nederlands tijdschrift voor geneeskunde, 1999, Dec-11, Volume: 143, Issue:50

    Topics: Anti-Ulcer Agents; Cimetidine; Dyspepsia; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Netherlands; Omeprazole; Peptic Ulcer; Stomach Ulcer; Zollinger-Ellison Syndrome

1999
Prevention and treatment of stress ulcers in critically ill patients.
    Seminars in gastrointestinal disease, 2003, Volume: 14, Issue:1

    Topics: Aged; Anti-Ulcer Agents; Cimetidine; Critical Illness; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Incidence; Myocardial Infarction; Omeprazole; Proton Pump Inhibitors; Risk Factors; Stomach Ulcer; Stress, Physiological

2003
Intravenous proton-pump inhibitors versus H2-antagonists for treatment of GI bleeding.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Cimetidine; Drug Administration Schedule; Enzyme Inhibitors; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Infusions, Intravenous; Injections, Intravenous; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ranitidine; Sulfoxides

2003
[Bronchial asthma and gastroesophageal reflux disease: are they interrelated by chance?].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:1

    Topics: Adult; Algorithms; Anti-Ulcer Agents; Asthma; Bronchodilator Agents; Cimetidine; Controlled Clinical Trials as Topic; Endoscopy, Digestive System; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Middle Aged; Omeprazole; Placebos; Ranitidine; Respiratory Function Tests; Time Factors

2005
[Safety of proton pump inhibitors].
    Medicina clinica, 2006, Nov-25, Volume: 127, Issue:20

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Age Factors; Aged; Animals; Anti-Ulcer Agents; Cimetidine; Enzyme Inhibitors; Famotidine; Female; Fetus; Histamine H2 Antagonists; Humans; Lactation; Lansoprazole; Meta-Analysis as Topic; Nizatidine; Omeprazole; Pantoprazole; Pregnancy; Proton Pump Inhibitors; Proton-Translocating ATPases; Rabeprazole; Ranitidine; Safety; Time Factors

2006
The efficacy and safety of proton pump inhibitors vs histamine-2 receptor antagonists for stress ulcer bleeding prophylaxis among critical care patients: a meta-analysis.
    Critical care medicine, 2010, Volume: 38, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Cimetidine; Critical Care; Histamine H2 Antagonists; Humans; Odds Ratio; Omeprazole; Pantoprazole; Peptic Ulcer Hemorrhage; Proton Pump Inhibitors; Ranitidine; Risk; Stress, Psychological

2010
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
    Current pharmaceutical design, 2013, Volume: 19, Issue:1

    Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine

2013
Pharmacologic treatment of GERD: Where we are now, and where are we going?
    Annals of the New York Academy of Sciences, 2020, Volume: 1482, Issue:1

    Topics: Cimetidine; Esomeprazole; Esophageal Mucosa; Gastroesophageal Reflux; Humans; Lansoprazole; Omeprazole; Proton Pump Inhibitors; Pyrroles; Sulfonamides

2020

Trials

58 trial(s) available for omeprazole and cimetidine

ArticleYear
Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome.
    Gastroenterology, 1992, Volume: 102, Issue:3

    Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Female; Follow-Up Studies; Gastric Acid; Gastric Mucosa; Gastrinoma; Gastrins; Humans; Male; Middle Aged; Omeprazole; Pancreatic Neoplasms; Postoperative Period; Prospective Studies; Ranitidine; Sex Factors; Time Factors; Zollinger-Ellison Syndrome

1992
Lack of effect of omeprazole, cimetidine, and ranitidine on the pharmacokinetics of ethanol in fasting male volunteers.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:2

    Topics: Adult; Cimetidine; Ethanol; Fasting; Humans; Male; Omeprazole; Ranitidine

1992
Treatment of refractory peptic ulcer with omeprazole or continued H2 receptor antagonists: a controlled clinical trial.
    Gut, 1991, Volume: 32, Issue:4

    Topics: Cimetidine; Double-Blind Method; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Ranitidine; Stomach Ulcer

1991
Treatment of peptic ulcer in general practice and in hospital: a comparison of omeprazole and cimetidine.
    The British journal of clinical practice, 1990, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Double-Blind Method; Family Practice; Female; Humans; Male; Middle Aged; Omeprazole; Outpatient Clinics, Hospital; Peptic Ulcer; Randomized Controlled Trials as Topic

1990
Double blind comparison of omeprazole (40 mg od) versus cimetidine (400 mg qd) in the treatment of symptomatic erosive reflux oesophagitis, assessed endoscopically, histologically and by 24 h pH monitoring.
    Gut, 1990, Volume: 31, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Double-Blind Method; Esophagitis, Peptic; Esophagus; Humans; Hydrogen-Ion Concentration; Middle Aged; Omeprazole; Randomized Controlled Trials as Topic; Time Factors

1990
Comparison of omeprazole and cimetidine in reflux oesophagitis: symptomatic, endoscopic, and histological evaluations.
    Gut, 1990, Volume: 31, Issue:9

    Topics: Cimetidine; Double-Blind Method; Esophagitis, Peptic; Esophagoscopy; Esophagus; Female; Humans; Male; Middle Aged; Omeprazole

1990
Effect of omeprazole and cimetidine on plasma diazepam levels.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:1

    Topics: Adult; Cimetidine; Diazepam; Double-Blind Method; Drug Interactions; Half-Life; Humans; Male; Nordazepam; Omeprazole

1990
Randomised, double blind comparison of omeprazole and cimetidine in the treatment of symptomatic gastric ulcer.
    Gut, 1990, Volume: 31, Issue:4

    Topics: Cimetidine; Double-Blind Method; Humans; Omeprazole; Random Allocation; Stomach Ulcer

1990
Omeprazole or cimetidine once daily for the treatment of duodenal ulcers?
    Journal of gastroenterology and hepatology, 1989, Volume: 4 Suppl 2

    Topics: Adult; Cimetidine; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole

1989
Symptom relief and duodenal ulcer healing with omeprazole or cimetidine. Opus (Omeprazole Peptic Ulcer Study) Research Group.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cimetidine; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Prognosis; Smoking

1989
Omeprazole and cimetidine in the treatment of ulcers of the body of the stomach: a double blind comparative trial. Danish Omeprazole Study Group.
    BMJ (Clinical research ed.), 1989, Mar-11, Volume: 298, Issue:6674

    Topics: Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Omeprazole; Pain; Random Allocation; Stomach; Stomach Ulcer; Time Factors; Wound Healing

1989
Omeprazole and cimetidine in treating ulcers of the body of the stomach.
    BMJ (Clinical research ed.), 1989, May-06, Volume: 298, Issue:6682

    Topics: Cimetidine; Humans; Omeprazole; Stomach Ulcer

1989
Omeprazole in the treatment of duodenal ulcer.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Adenosine Triphosphatases; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; H(+)-K(+)-Exchanging ATPase; Humans; Omeprazole; Parietal Cells, Gastric; Ranitidine

1989
[Is strong inhibition of gastric acid in the treatment of peptic ulcer sensible?].
    Nederlands tijdschrift voor geneeskunde, 1989, Apr-01, Volume: 133, Issue:13

    Topics: Cimetidine; Clinical Trials as Topic; Double-Blind Method; Gastric Acid; Histamine H2 Antagonists; Humans; Omeprazole; Peptic Ulcer; Random Allocation; Ranitidine

1989
Relapse of gastric ulcers after healing with omeprazole and cimetidine. A double-blind follow-up study. Danish Omeprazole Study Group.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Omeprazole; Recurrence; Smoking; Stomach Ulcer

1989
Double blind multicentre comparison of omeprazole 20 mg once daily versus ranitidine 150 mg twice daily in the treatment of cimetidine or ranitidine resistant duodenal ulcers.
    Gut, 1989, Volume: 30, Issue:9

    Topics: Adult; Cimetidine; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Duodenal Ulcer; Female; Humans; Male; Multicenter Studies as Topic; Omeprazole; Ranitidine

1989
Randomised, double blind comparison of omeprazole and cimetidine in the treatment of symptomatic gastric ulcer.
    Gut, 1989, Volume: 30, Issue:10

    Topics: Cimetidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Omeprazole; Randomized Controlled Trials as Topic; Stomach Ulcer

1989
The clinical safety of omeprazole.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Cimetidine; Clinical Trials as Topic; Esophagitis, Peptic; Humans; Liver Function Tests; Omeprazole; Peptic Ulcer; Ranitidine; Thyroid Function Tests; Zollinger-Ellison Syndrome

1989
Omeprazole in the treatment of prepyloric ulcer: review of the results of the Danish Omeprazole Study Group.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Adult; Cimetidine; Denmark; Double-Blind Method; Follow-Up Studies; Gastric Acid; Humans; Middle Aged; Omeprazole; Randomized Controlled Trials as Topic; Stomach Ulcer

1989
Omeprazole in the acute treatment of gastric ulcer.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Cimetidine; Clinical Trials as Topic; Humans; Omeprazole; Ranitidine; Stomach Ulcer; Wound Healing

1989
The effects of omeprazole and cimetidine on duodenal ulcer healing and the relief of symptoms.
    Alimentary pharmacology & therapeutics, 1988, Volume: 2, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole

1988
[Drug therapy of peptic ulcer. What is coming up?].
    Leber, Magen, Darm, 1987, Volume: 17, Issue:1

    Topics: Alprostadil; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Enprostil; Humans; Misoprostol; Omeprazole; Peptic Ulcer; Prostaglandins E, Synthetic; Ranitidine

1987
Effect of omeprazole and cimetidine on prepyloric gastric ulcer: double blind comparative trial.
    Gut, 1988, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Omeprazole; Random Allocation; Stomach Ulcer

1988
[Comparative efficacy of omeprazole and cimetidine in the treatment of duodenal ulcer in the acute stage. A French multicenter, controlled therapeutic trial].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:11

    Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Random Allocation; Time Factors

1987
Omeprazole (20 mg daily) versus cimetidine (1200 mg daily) in duodenal ulcer healing and pain relief.
    Gastroenterology, 1988, Volume: 94, Issue:5 Pt 1

    Topics: Adult; Aged; Antacids; Cimetidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Pain; Random Allocation

1988
Effect of omeprazole and cimetidine on duodenal ulcer. A double-blind comparative trial.
    The New England journal of medicine, 1985, Apr-11, Volume: 312, Issue:15

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Follow-Up Studies; Humans; Male; Middle Aged; Omeprazole; Pain; Random Allocation; Recurrence; Wound Healing

1985
Treatment of ulcer disease.
    The Alabama journal of medical sciences, 1985, Volume: 22, Issue:1

    Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Clinical Trials as Topic; Gastric Acid; Humans; Omeprazole; Peptic Ulcer; Ranitidine; Sucralfate

1985
Omeprazole inhibition of nocturnal gastric secretion in patients with duodenal ulcer.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Dose-Response Relationship, Drug; Duodenal Ulcer; Gastric Acid; Gastric Acidity Determination; Humans; Male; Middle Aged; Omeprazole; Time Factors

1984
Evaluation of gastric ulcer healing by lansoprazole by measurement of ulcer diameter.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Gastroscopy; Histamine H2 Antagonists; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Stomach Ulcer

1995
[Omeprazole and cimetidine in the treatment of upper digestive hemorrhage].
    Revista espanola de enfermedades digestivas, 1994, Volume: 86, Issue:6

    Topics: Cimetidine; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Omeprazole; Prospective Studies

1994
Histological maturity of healed duodenal ulcer and ulcer recurrence after treatment with omeprazole or cimetidine.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Adolescent; Adult; Aged; Cimetidine; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Recurrence; Single-Blind Method

1994
Changes of resorption and metabolism of cyclosporine after heart transplantation by the influence of gastrointestinal agents.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Administration, Oral; Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Antilymphocyte Serum; Azathioprine; Cimetidine; Cyclosporine; Drug Combinations; Famotidine; Female; Heart Transplantation; Humans; Intestinal Absorption; Magnesium Hydroxide; Male; Middle Aged; Omeprazole; Pirenzepine; Prednisone; Rats; Rats, Inbred BN

1994
Comparison of omeprazole and histamine H2-receptor antagonists in the treatment of elderly and young patients with reflux oesophagitis.
    Age and ageing, 1994, Volume: 23, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Esophagitis, Peptic; Esophagoscopy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Omeprazole; Ranitidine; Treatment Outcome; Wound Healing

1994
Between-subject and within-subject variations in the pharmacokinetics of ethanol.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:5

    Topics: Administration, Oral; Adult; Analysis of Variance; Chromatography, Gas; Cimetidine; Ethanol; Half-Life; Humans; Intestinal Absorption; Male; Omeprazole; Random Allocation; Ranitidine

1994
Clinical evaluation of the effect of omeprazole, cimetidine, famotidine and ranitidine on histamine induced cutaneous wheal and flare response.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:7

    Topics: Adult; Cimetidine; Drug Hypersensitivity; Dyspepsia; Famotidine; Female; Histamine; Histamine H2 Antagonists; Humans; India; Male; Middle Aged; Omeprazole; Ranitidine

1993
Comparative effects of adjuvant cimetidine and omeprazole during pancreatic enzyme replacement therapy.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:5

    Topics: Adult; Aged; Celiac Disease; Cimetidine; Double-Blind Method; Exocrine Pancreatic Insufficiency; Female; Gastric Acid; Humans; Lipase; Male; Middle Aged; Omeprazole; Pancreatic Extracts; Pancrelipase

1994
Antisecretory effect of three premeal doses of cimetidine 400 mg versus a single morning dose of omeprazole 20 mg: pathophysiological implications for duodenal ulcer treatment.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:7

    Topics: Adult; Aged; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Eating; Female; Gastric Acid; Gastric Acidity Determination; Humans; Male; Middle Aged; Omeprazole; Single-Blind Method

1993
Comparison of omeprazole with cimetidine for prophylaxis of acid aspiration in elective surgery.
    European journal of anaesthesiology, 1993, Volume: 10, Issue:3

    Topics: Administration, Oral; Adult; Cimetidine; Double-Blind Method; Dye Dilution Technique; Female; Gastric Acid; Gastric Acidity Determination; Gastrointestinal Contents; Humans; Male; Middle Aged; Omeprazole; Phenolsulfonphthalein; Placebos; Pneumonia, Aspiration; Postoperative Complications; Surgical Procedures, Operative

1993
Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole.
    Journal of clinical gastroenterology, 1996, Volume: 23, Issue:1

    Topics: Adult; Anti-Ulcer Agents; Candidiasis; Cimetidine; Duodenal Diseases; Duodenal Ulcer; Famotidine; Female; Gastric Acidity Determination; Humans; Male; Omeprazole; Prospective Studies

1996
Bacterial overgrowth during treatment with omeprazole compared with cimetidine: a prospective randomised double blind study.
    Gut, 1996, Volume: 39, Issue:1

    Topics: Adult; Aged; Anti-Ulcer Agents; Bacteria; Cimetidine; Double-Blind Method; Duodenum; Female; Humans; Male; Middle Aged; Nitroso Compounds; Omeprazole; Peptic Ulcer; Prospective Studies; Stomach

1996
Transforming growth factor-alpha (TGF-alpha) levels in human proximal gastrointestinal epithelium. Effect of mucosal injury and acid inhibition.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy, Needle; Cimetidine; Duodenum; Gastric Acid; Gastric Mucosa; Humans; Intestinal Mucosa; Omeprazole; Peptic Ulcer; Pyloric Antrum; Radioimmunoassay; Transforming Growth Factor alpha

1997
Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Cimetidine; Double-Blind Method; Esophagitis; Female; Gastroesophageal Reflux; Heartburn; Humans; Male; Middle Aged; Omeprazole; Patient Satisfaction

1997
A prospective randomized comparative trial showing that omeprazole prevents rebleeding in patients with bleeding peptic ulcer after successful endoscopic therapy.
    Archives of internal medicine, 1998, Jan-12, Volume: 158, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Blood Transfusion; Cimetidine; Female; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Prospective Studies; Recurrence; Treatment Outcome

1998
Histamine H2 receptor antagonist-refractory oesophagitis: the efficacy of long-term omeprazole maintenance treatment.
    Italian journal of gastroenterology and hepatology, 1997, Volume: 29, Issue:6

    Topics: Adult; Aged; Biopsy; Cimetidine; Drug Administration Schedule; Drug Resistance; Enzyme Inhibitors; Esophagitis, Peptic; Esophagus; Female; Follow-Up Studies; Gastric Mucosa; Gastrins; Gastroscopy; Histamine H2 Antagonists; Humans; Hyperplasia; Male; Middle Aged; Omeprazole; Ranitidine; Recurrence; Treatment Outcome; Wound Healing

1997
Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:1

    Topics: Administration, Oral; Anti-Ulcer Agents; Chi-Square Distribution; Cimetidine; Double-Blind Method; Esophagitis; Female; Gastroesophageal Reflux; Heartburn; Histamine H2 Antagonists; Humans; Male; Omeprazole; Secondary Prevention; Treatment Outcome

1998
Effect of omeprazole and cimetidine on plasma aldosterone response to angiotensin II.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Anti-Ulcer Agents; Blood Pressure; Cimetidine; Furosemide; Histamine H2 Antagonists; Humans; Male; Omeprazole; Potassium; Renin; Sodium

1998
[Comparison of the therapeutic effects and acid suppression of H2-receptor antagonist and proton pump inhibitor in patients with gastric body ulcer--a prospective controlled trial].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1999, Volume: 96, Issue:5

    Topics: Anti-Ulcer Agents; Cimetidine; Female; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Prospective Studies; Proton Pumps; Stomach Ulcer

1999
A prospective randomized comparative trial showing that omeprazole prevents rebleeding in patients with bleeding peptic ulcers after successful endoscopic therapy.
    Gastrointestinal endoscopy, 1999, Volume: 50, Issue:2

    Topics: Administration, Oral; Anti-Ulcer Agents; Cimetidine; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocoagulation; Endoscopy; Female; Humans; Infusions, Intravenous; Male; Omeprazole; Peptic Ulcer Hemorrhage

1999
Assessment of decisions in the treatment of Helicobacter pylori-related duodenal ulcer: a cost-effectiveness study.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:10

    Topics: Adolescent; Adult; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; China; Cimetidine; Cost-Benefit Analysis; Disease Management; Drug Therapy, Combination; Duodenal Ulcer; Female; Helicobacter Infections; Humans; Male; Metronidazole; Middle Aged; Omeprazole; Recurrence; Treatment Outcome

1999
Effect of intragastric pH on control of peptic ulcer bleeding.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation; Rats; Retrospective Studies; Stomach Ulcer

2000
A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2001, Volume: 51, Issue:469

    Topics: Anti-Ulcer Agents; Cimetidine; Cisapride; Clinical Protocols; Dyspepsia; Endoscopy, Gastrointestinal; Family Practice; Female; Humans; Male; Odds Ratio; Omeprazole; Practice Guidelines as Topic; Ranitidine; Retrospective Studies; Treatment Outcome

2001
Omeprazole is more effective than a histamine H2-receptor blocker for maintaining a persistent elevation of gastric pH after colon resection for cancer.
    American journal of surgery, 2004, Volume: 187, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidine; Colonic Neoplasms; Female; Gastric Acidity Determination; Gastric Mucosa; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Omeprazole; Ranitidine; Stomach

2004
Randomized, double-blind comparison of immediate-release omeprazole oral suspension versus intravenous cimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients.
    Critical care medicine, 2005, Volume: 33, Issue:4

    Topics: Administration, Oral; Aged; Anti-Ulcer Agents; Cimetidine; Critical Care; Dosage Forms; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Male; Middle Aged; Omeprazole; Stomach; Survival Analysis; Suspensions; Treatment Outcome

2005
The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects.
    British journal of clinical pharmacology, 2005, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Cimetidine; Citalopram; Depressive Disorder; Drug Therapy, Combination; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Selective Serotonin Reuptake Inhibitors

2005
A comparison of oral omeprazole and intravenous cimetidine in reducing complications of duodenal peptic ulcer.
    BMC gastroenterology, 2006, Jan-11, Volume: 6

    Topics: Administration, Oral; Adult; Aged; Anti-Ulcer Agents; Blood Transfusion; Cimetidine; Duodenal Ulcer; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous; Length of Stay; Middle Aged; Omeprazole; Secondary Prevention

2006
Role of intravenous omeprazole in patients with high-risk peptic ulcer bleeding after successful endoscopic epinephrine injection: a prospective randomized comparative trial.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:3

    Topics: Adult; Aged; Anti-Ulcer Agents; Blood Transfusion; Cimetidine; Drug Administration Schedule; Electrocoagulation; Epinephrine; Female; Gastroscopy; Humans; Infusions, Intravenous; Injections, Intralesional; Male; Omeprazole; Peptic Ulcer Hemorrhage; Prospective Studies; Proton Pump Inhibitors; Recurrence; Risk Factors

2006
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
    Current pharmaceutical design, 2013, Volume: 19, Issue:1

    Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine

2013
A randomized controlled study comparing omeprazole and cimetidine for the prophylaxis of stress-related upper gastrointestinal bleeding in patients with intracerebral hemorrhage.
    Journal of neurosurgery, 2013, Volume: 118, Issue:1

    Topics: Adult; Aged; Anti-Ulcer Agents; Cerebral Hemorrhage; Cimetidine; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Omeprazole; Stress, Psychological; Treatment Outcome

2013

Other Studies

185 other study(ies) available for omeprazole and cimetidine

ArticleYear
Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Adenosine Triphosphatases; Amines; Aminopyrine; Animals; Benzothiazoles; Benzoxazoles; Bucladesine; Chemical Phenomena; Chemistry; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Ligation; Male; Omeprazole; Parietal Cells, Gastric; Pyloric Antrum; Ranitidine; Rats; Structure-Activity Relationship; Thiazoles

1988
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Antiulcer drugs and gastric mucosal integrity. Effects of misoprostol, 16,16-dimethyl PGE2, and cimetidine on hemodynamics and metabolic rate in canine gastric mucosa.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:7

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Ulcer Agents; Cell Membrane Permeability; Cimetidine; Dogs; Female; Gastric Mucosa; Male; Misoprostol; Omeprazole; Oxygen Consumption; Potassium Channels; Regional Blood Flow; Sodium Channels

1992
Use of cimetidine and other peptic ulcer drugs in Denmark 1977-1990 with analysis of the risk of gastric cancer among cimetidine users.
    Gut, 1992, Volume: 33, Issue:9

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cimetidine; Cohort Studies; Denmark; Female; Histamine H2 Antagonists; Humans; Long-Term Care; Male; Middle Aged; Omeprazole; Peptic Ulcer; Risk Factors; Stomach Neoplasms; Time Factors

1992
Effects of histamine H2-receptor antagonists and a proton pump inhibitor on the mucosal hydroxyproline content of ethanol-HCl-induced gastric lesions in rats.
    Digestion, 1992, Volume: 51, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Collagen; Ethanol; Famotidine; Gastric Mucosa; Hydrochloric Acid; Hydroxyproline; Male; Omeprazole; Rabeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer

1992
[Effect of long-term administration of antisecretary drugs on rat gastric histamine synthesis and acid secretion--compare with omeprazole and cimetidine].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1992, Volume: 89, Issue:10

    Topics: Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Male; Omeprazole; Rats; Rats, Wistar

1992
Influence of acid-secretion blockers on gastric and hepatic alcohol dehydrogenase in rat.
    Scandinavian journal of clinical and laboratory investigation, 1992, Volume: 52, Issue:7

    Topics: Alcohol Dehydrogenase; Animals; Cimetidine; Gastric Mucosa; Isoenzymes; Kinetics; Liver; Male; Omeprazole; Ranitidine; Rats; Rats, Wistar

1992
Further evidence for an interaction between alcohol and certain H2-receptor antagonists.
    Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:6

    Topics: Adult; Alcoholic Intoxication; Cimetidine; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Omeprazole; Ranitidine

1991
Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
    Digestion, 1990, Volume: 47, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Cimetidine; Dose-Response Relationship, Drug; Granulation Tissue; Male; Neovascularization, Pathologic; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing

1990
Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs.
    American journal of veterinary research, 1991, Volume: 52, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Dog Diseases; Dogs; Double-Blind Method; Gastritis; Gastroscopy; Male; Omeprazole; Random Allocation; Stomach Ulcer

1991
A new method for evaluating gastric ulcer healing by endoscopic ultrasonography.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:5

    Topics: Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; Female; Gastroscopy; Gefarnate; Humans; Male; Methods; Middle Aged; Omeprazole; Stomach; Stomach Ulcer; Ultrasonography

1991
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat.
    The American journal of medicine, 1991, Aug-08, Volume: 91, Issue:2A

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hydrocortisone; Lansoprazole; Male; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Sucralfate; Wound Healing

1991
Role of gastric mucosal blood flow in cytoprotection.
    Digestion, 1991, Volume: 48, Issue:2

    Topics: Alprostadil; Animals; Anti-Ulcer Agents; Cimetidine; Ethanol; Gastric Mucosa; Lasers; Male; Misoprostol; Omeprazole; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer; Sucralfate

1991
Comparative tolerability profile of omeprazole in clinical trials.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Cimetidine; Clinical Trials as Topic; Drug Interactions; Duodenal Ulcer; Follow-Up Studies; Gastroesophageal Reflux; Humans; Middle Aged; Omeprazole; Ranitidine; Zollinger-Ellison Syndrome

1991
Pharmacological agents of gastric acid secretion: receptor antagonists and pump inhibitors.
    Methods in enzymology, 1990, Volume: 191

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Carbachol; Carbon Radioisotopes; Cell Separation; Cimetidine; Epithelial Cells; Epithelium; Gastric Acid; Gastric Mucosa; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Histamine; Male; Models, Biological; Omeprazole; Parietal Cells, Gastric; Pepsinogens; Radioisotope Dilution Technique; Ranitidine; Rats; Receptors, Cell Surface

1990
Omeprazole and genotoxicity.
    Lancet (London, England), 1990, Feb-17, Volume: 335, Issue:8686

    Topics: Animals; Cimetidine; DNA; DNA Repair; Gastric Acid; Gastric Mucosa; Humans; Omeprazole; Rats; Thymidine; Time Factors

1990
Histology of gastric biopsies from peptic ulcer patients before and after short-term treatment with omeprazole or H2-receptor antagonists.
    Virchows Archiv. A, Pathological anatomy and histopathology, 1990, Volume: 417, Issue:4

    Topics: Adult; Cimetidine; Female; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Ranitidine

1990
Direct comparison between the ulcer-healing effects of two H(+)-K(+)-ATPase inhibitors, one M1-selective antimuscarinic and one H2 receptor antagonist in the rat.
    Pharmacology, 1990, Volume: 41, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Duodenal Ulcer; H(+)-K(+)-Exchanging ATPase; Histamine H2 Antagonists; Male; Muscarinic Antagonists; Omeprazole; Pantoprazole; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Stomach Ulcer; Sulfoxides

1990
Coupling of H(+)-K(+)-ATPase activity and glucose oxidation in gastric glands.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: Adenosine Triphosphatases; Aminopyrine; Ammonia; Animals; Anti-Ulcer Agents; Atropine; Bucladesine; Carbachol; Carbon Dioxide; Cimetidine; Gastric Mucosa; Glucose; Glycolysis; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; In Vitro Techniques; Kinetics; Models, Biological; Omeprazole; Oxygen Consumption; Rats

1990
Effect of Ostertagia ostertagi secretions and various putative secretagogues and inhibitors on aminopyrine accumulation in dispersed bovine abomasal gland cells.
    Research in veterinary science, 1990, Volume: 49, Issue:3

    Topics: Abomasum; Aminopyrine; Animals; Bucladesine; Cattle; Cell Survival; Cells, Cultured; Cimetidine; Gastric Mucosa; Omeprazole; Ostertagia; Pentagastrin; Thiocyanates

1990
Effect of basolateral acidification on the frog oxynticopeptic cell.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1

    Topics: Animals; Cimetidine; Colforsin; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Rana catesbeiana

1990
Omeprazole--a useful new agent?
    British journal of anaesthesia, 1990, Volume: 65, Issue:5

    Topics: Administration, Oral; Antacids; Cimetidine; Gastric Acid; Gastric Juice; Humans; Omeprazole; Preanesthetic Medication; Ranitidine

1990
Omeprazole in the treatment of erosive oesophagitis refractory to high dose cimetidine and ranitidine.
    Gut, 1990, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Esophagitis; Female; Humans; Male; Middle Aged; Omeprazole; Ranitidine

1990
Cimetidine and omeprazole have different effects on hepatic extraction of lidocaine in rats.
    Gastroenterology, 1990, Volume: 99, Issue:3

    Topics: Animals; Cimetidine; Indocyanine Green; Lidocaine; Liver; Male; Omeprazole; Rats; Rats, Inbred Strains

1990
The isolated stomach preparation of the mouse: a physiological unit for pharmacological analysis.
    British journal of pharmacology, 1985, Volume: 86, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine Derivatives; Benzimidazoles; Cimetidine; Fasting; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mice; Muscarine; Omeprazole; Pentagastrin; Pressure; Tetrodotoxin; Thiocyanates

1985
Proton pump inhibition--the ultimate control of acid secretion?
    The Journal of surgical research, 1986, Volume: 40, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminopyrine; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Depression, Chemical; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Ion Channels; Omeprazole; Parietal Cells, Gastric; Protons; Rabbits

1986
Histamine synthesis after administration of gastrin and blockade of acid secretion in the rat stomach.
    The Tokai journal of experimental and clinical medicine, 1989, Volume: 14, Issue:4

    Topics: Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Histamine; Histidine Decarboxylase; Male; Omeprazole; Rats; Rats, Inbred Strains; Tetragastrin

1989
Histamine H2-receptor mediated stimulation of gastric acid secretion by mercaptomethylimidazole.
    Biochemical pharmacology, 1989, Mar-15, Volume: 38, Issue:6

    Topics: Animals; Cimetidine; Gastric Acid; Male; Methimazole; Mice; Mice, Inbred BALB C; Nifedipine; Omeprazole; Parietal Cells, Gastric; Potassium; Proton-Translocating ATPases; Pylorus; Receptors, Histamine H2; Sodium; Verapamil

1989
Effect of cimetidine, ranitidine, famotidine and omeprazole on hepatocyte proliferation in vitro.
    Journal of hepatology, 1989, Volume: 8, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Cimetidine; DNA; Famotidine; Hepatectomy; Histamine H2 Antagonists; Hormones; Liver; Omeprazole; Osmolar Concentration; Ranitidine; Rats; Rats, Inbred F344; Thiazoles

1989
Effects of omeprazole on acid secretion and acid-related symptoms in patients with Zollinger-Ellison syndrome.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166

    Topics: Adult; Aged; Cimetidine; Female; Gastric Acid; Gastrins; Humans; Long-Term Care; Male; Middle Aged; Multiple Endocrine Neoplasia; Omeprazole; Ranitidine; Zollinger-Ellison Syndrome

1989
Healing process of duodenal ulcers induced by indomethacin plus histamine in rats.
    Digestion, 1989, Volume: 42, Issue:4

    Topics: Animals; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Gastric Acid; Histamine; Hydrogen-Ion Concentration; Indomethacin; Male; Omeprazole; Propantheline; Rats; Rats, Inbred Strains

1989
Histological evaluation of mast cells in rat gastric mucosal lesions induced by compound 48/80.
    Digestion, 1989, Volume: 43, Issue:1-2

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Connective Tissue; Gastric Mucosa; Male; Mast Cells; Omeprazole; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains

1989
Effects of H2-receptor antagonists upon physiological acid secretory states in animals.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: Animals; Benzimidazoles; Cimetidine; Famotidine; Gastric Emptying; Gastric Juice; Histamine H2 Antagonists; Male; Omeprazole; Rats; Secretory Rate; Thiadiazoles; Thiazoles

1985
Effectiveness of omeprazole in seven patients with Zollinger-Ellison syndrome resistant to histamine H2-receptor antagonists.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:7

    Topics: Adult; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Cimetidine; Drug Resistance; Drug Therapy, Combination; Female; Gastric Acid; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Pirenzepine; Ranitidine; Zollinger-Ellison Syndrome

1986
Influence of the stimulation state of the parietal cells on the inhibitory effect of omeprazole on gastric acid secretion in dogs.
    Gastroenterology, 1986, Volume: 91, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Dogs; Drug Interactions; Gastric Acid; Omeprazole; Parietal Cells, Gastric; Pentagastrin; Somatostatin

1986
Some profiles of transmucosal potential difference in rat stomach determined in situ with special reference to effects of timoprazole, a H+,K+-ATPase inhibitor.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Atropine; Benzimidazoles; Bethanechol; Bethanechol Compounds; Cimetidine; Diphenhydramine; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Male; Membrane Potentials; Omeprazole; Rats; Rats, Inbred Strains; Tetragastrin

1986
Potentiation of the gastric antisecretory activity of histamine H2-receptor antagonists by clebopride.
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:5

    Topics: Animals; Benzamides; Cimetidine; Drug Synergism; Gastric Acid; Histamine H2 Antagonists; Male; Omeprazole; Pirenzepine; Pylorus; Ranitidine; Rats; Rats, Inbred Strains

1988
Effect of cimetidine, ranitidine and omeprazole on postprandial gastrin and somatostatin release in conscious dogs.
    Regulatory peptides, 1988, Volume: 22, Issue:3

    Topics: Animals; Cimetidine; Dogs; Food; Gastric Juice; Gastrins; Omeprazole; Ranitidine; Somatostatin; Wakefulness

1988
Resistant duodenal ulcer: when, why and what to do?
    Postgraduate medical journal, 1988, Volume: 64, Issue:751

    Topics: Aged; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Histamine H2 Antagonists; Humans; Male; Omeprazole; Organometallic Compounds; Recurrence

1988
Duodenal ulcers that are difficult to heal.
    BMJ (Clinical research ed.), 1988, Dec-17, Volume: 297, Issue:6663

    Topics: Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Histamine H2 Antagonists; Humans; Omeprazole; Ranitidine

1988
Does early antisecretory treatment limit ulcer development?
    Gastroenterology, 1989, Volume: 96, Issue:3

    Topics: Animals; Cimetidine; Omeprazole; Rats; Stomach Ulcer; Time Factors

1989
Omeprazole and cimetidine versus pentagastrin in canine ex vivo gastric chamber.
    The American journal of physiology, 1989, Volume: 256, Issue:2 Pt 1

    Topics: Animals; Cimetidine; Dogs; Female; Gastric Acid; Gastric Juice; Gastric Mucosa; Male; Omeprazole; Oxygen Consumption; Pentagastrin; Potassium; Reference Values; Regional Blood Flow; Sodium; Vascular Resistance

1989
The mechanism of action of omeprazole--a survey of its inhibitory actions in vitro.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 108

    Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Antipyrine; Benzimidazoles; Bucladesine; Cimetidine; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; Male; Omeprazole; Parietal Cells, Gastric; Sodium-Potassium-Exchanging ATPase; Stomach; Swine

1985
Inhibitory action of omeprazole on acid formation in gastric glands and on H+,K+-ATPase isolated from human gastric mucosa.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:3

    Topics: Adenosine Triphosphatases; Aminopyrine; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Humans; In Vitro Techniques; Omeprazole; Stomach Ulcer

1986
Mechanism of action of omeprazole.
    Scandinavian journal of gastroenterology. Supplement, 1986, Volume: 118

    Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; In Vitro Techniques; Models, Biological; Omeprazole

1986
Cyclic AMP in gastric juice does not reflect histamine H2 receptor activity in Heidenhain pouch dog.
    Gastroenterologia Japonica, 1986, Volume: 21, Issue:5

    Topics: Animals; Cimetidine; Cyclic AMP; Dogs; Gastric Juice; Omeprazole; Receptors, Histamine H2; Stomach

1986
Sites of resistance changes with inhibition of acid secretion in frog stomach.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 1

    Topics: Animals; Barium; Benzimidazoles; Bufo marinus; Chlorides; Cimetidine; Drug Tolerance; Electrophysiology; Gastric Acid; Gastric Fundus; Gastric Mucosa; Hypotonic Solutions; Omeprazole; Pyloric Antrum; Rana catesbeiana; Rana pipiens; Thiocyanates

1986
Indomethacin-induced gastric antral ulcers in hamsters.
    Gastroenterology, 1988, Volume: 95, Issue:4

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cricetinae; Dinoprostone; Disease Models, Animal; Gastric Acid; Indomethacin; Injections, Subcutaneous; Male; Mesocricetus; Omeprazole; Peptic Ulcer Perforation; Prostaglandins E; Stomach Ulcer; Time Factors

1988
Effects of topical application of acidified omeprazole on acid secretion and transmucosal potential difference in anesthetized rat stomachs.
    Japanese journal of pharmacology, 1988, Volume: 47, Issue:4

    Topics: Administration, Cutaneous; Animals; Cimetidine; Cysteine; Electrodes; Gastric Acid; Gastric Mucosa; Histamine; Histamine Antagonists; Hydrogen-Ion Concentration; Male; Omeprazole; Rats; Rats, Inbred Strains; Urethane

1988
[Inhibitory effects of omeprazole and cimetidine on the formation of gastric ulcer in rats with obstructive jaundice and acute renal failure].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1988, Volume: 85, Issue:6

    Topics: Acute Kidney Injury; Animals; Cholestasis; Cimetidine; Gastric Mucosa; Male; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological

1988
Effect of omeprazole and cimetidine on healing of chronic gastric ulcers and gastric acid secretion in rats.
    The Tohoku journal of experimental medicine, 1988, Volume: 155, Issue:4

    Topics: Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Male; Omeprazole; Pentagastrin; Rats; Rats, Inbred Strains; Reference Values; Stomach Ulcer

1988
An acid-independent antiulcer effect of M1 antimuscarinics in the rat.
    Pharmacology, 1988, Volume: 37 Suppl 1

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cysteamine; Duodenal Ulcer; Female; Gastric Acid; Omeprazole; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic

1988
The interaction of omeprazole with rat liver cytochrome P450-mediated monooxygenase reactions in vitro and in vivo.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Cimetidine; Diazepam; Ethylmorphine-N-Demethylase; In Vitro Techniques; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Omeprazole; Oxidoreductases; Oxygenases; Rats; Rats, Inbred Strains; Species Specificity

1988
Potential difference responses to nutrient K+, Cl- and Na+ changes in secreting and resting states of frog stomach.
    Biochimica et biophysica acta, 1988, Apr-07, Volume: 939, Issue:2

    Topics: Animals; Chlorides; Cimetidine; Electric Conductivity; Gastric Acid; Gastric Mucosa; Membrane Potentials; Omeprazole; Potassium; Rana pipiens; Sodium; Thiocyanates

1988
A new in vivo method for repeatedly studying gastric acid secretion and other secretory parameters in awake guinea pig.
    The Journal of surgical research, 1987, Volume: 43, Issue:5

    Topics: Animals; Catheters, Indwelling; Cimetidine; Depression, Chemical; Dye Dilution Technique; Gastric Acid; Guinea Pigs; Histamine; Histamine Antagonists; Male; Omeprazole; Ranitidine; Stimulation, Chemical

1987
The effect of omeprazole on ultrastructural changes in gastric parietal cells.
    Gastroenterologia Japonica, 1988, Volume: 23, Issue:1

    Topics: Animals; Cimetidine; Gastric Acid; Guinea Pigs; Histamine; Male; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Vacuoles

1988
Gastric mucosal blood flow response to stimulation and inhibition of gastric acid secretion.
    Gastroenterology, 1988, Volume: 95, Issue:3

    Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Hydrogen; Male; Omeprazole; Pentagastrin; Rats; Rats, Inbred Strains; Regional Blood Flow; Stimulation, Chemical

1988
Long term management of hemorrhagic esophagitis with cimetidine and omeprazole.
    Australian and New Zealand journal of medicine, 1986, Volume: 16, Issue:2

    Topics: Anemia; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Esophagitis; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Omeprazole

1986
Effects of omeprazole on gastric mucosal blood flow in the conscious rat.
    Scandinavian journal of gastroenterology, 1987, Volume: 22, Issue:4

    Topics: Administration, Oral; Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Injections, Intravenous; Male; Omeprazole; Pentagastrin; Rats; Rats, Inbred Strains; Regional Blood Flow

1987
A long lasting gastrin response to apomorphine revealed by inhibitors of gastric acid secretion.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:1

    Topics: Animals; Apomorphine; Cimetidine; Dogs; Domperidone; Female; Gastric Acid; Gastrins; Haloperidol; Male; Omeprazole; Ranitidine; Vagotomy

1987
Cytoprotective action of histamine against 0.6 N HCl-induced gastric mucosal injury in rats; comparative study with adaptive cytoprotection induced by exogenous acid.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:3

    Topics: Adaptation, Physiological; Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Histamine; Hydrochloric Acid; Indomethacin; Male; Membrane Potentials; Omeprazole; Rats; Rats, Inbred Strains

1987
Effect of cimetidine and omeprazole on aspirin and taurocholate-induced gastric mucosal damage.
    Gut, 1986, Volume: 27, Issue:5

    Topics: Animals; Aspirin; Benzimidazoles; Cimetidine; Gastric Mucosa; Omeprazole; Rats; Taurocholic Acid

1986
Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Brunner Glands; Chronic Disease; Cimetidine; Cysteamine; Duodenal Ulcer; Female; Gastric Acid; Intestinal Mucosa; Omeprazole; Rats; Rats, Inbred Strains; Vagotomy

1986
Omeprazole: effects on oxidative drug metabolism in the rat.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:5

    Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Drug Interactions; Male; Omeprazole; Oxidation-Reduction; Pentobarbital; Rats; Rats, Inbred Strains; Sleep

1986
Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer.
    Gut, 1986, Volume: 27, Issue:9

    Topics: Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Gastric Acidity Determination; Humans; Imidazoles; Omeprazole; Ranitidine; Thiazoles

1986
Duodenal ulcer disease.
    Hospital practice (Office ed.), 1985, Aug-15, Volume: 20, Issue:8

    Topics: Anti-Ulcer Agents; Benzimidazoles; Campylobacter Infections; Cimetidine; Duodenal Ulcer; Duodenoscopy; Female; Gastric Mucosa; Humans; Male; Omeprazole; Pain; Prostaglandins; Ranitidine; Recurrence; Sex Factors; Stress, Psychological

1985
Effect of cimetidine and omeprazole on aspirin- and taurocholate-induced gastric mucosal damage in the rat.
    Gut, 1985, Volume: 26, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cimetidine; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Omeprazole; Rats; Rats, Inbred Strains; Taurocholic Acid

1985
Effect of cimetidine, ranitidine and omeprazole on hepatic flow of the artificially perfused rat liver.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:9

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Liver Circulation; Male; Omeprazole; Perfusion; Ranitidine; Rats; Rats, Inbred Strains

1985
Omeprazole, cimetidine, and ranitidine: inhibition of acid production in isolated human parietal cells.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:8

    Topics: Adult; Aged; Benzimidazoles; Cimetidine; Female; Gastric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Omeprazole; Parietal Cells, Gastric; Ranitidine; Receptors, Histamine H2; Time Factors

1985
Pepsin secretion: neurohumoral regulation and drug effects.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 101

    Topics: Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bucladesine; Carbachol; Cimetidine; Cycloheximide; Gastric Acid; Gastrins; Histamine; In Vitro Techniques; Mice; Models, Biological; Omeprazole; Parasympatholytics; Pepsin A; Secretory Rate

1984
Omeprazole in Zollinger-Ellison syndrome. Effects of a single dose and of long-term treatment in patients resistant to histamine H2-receptor antagonists.
    The New England journal of medicine, 1984, Mar-22, Volume: 310, Issue:12

    Topics: Adult; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Drug Evaluation; Drug Resistance; Gastric Acid; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Zollinger-Ellison Syndrome

1984
[Changes in therapy of duodenal ulcers. The European Gastro-Club 1983 discusses new pathophysiologic and epidemiologic data referring to drug and surgical therapy].
    Fortschritte der Medizin, 1983, Dec-15, Volume: 101, Issue:47-48

    Topics: Amino Acids; Benzimidazoles; Carbenoxolone; Cimetidine; Duodenal Ulcer; Gastric Acid; Histamine; Histamine H2 Antagonists; Humans; Omeprazole; Ranitidine; Stomach Neoplasms

1983
How potent is the inhibition of drug metabolism by omeprazole?
    Lancet (London, England), 1984, Sep-29, Volume: 2, Issue:8405

    Topics: Animals; Antipyrine; Benzimidazoles; Cimetidine; Drug Interactions; Half-Life; Humans; Liver; Omeprazole; Pharmaceutical Preparations; Rats

1984
Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+)ATPase.
    Nature, 1981, Mar-12, Volume: 290, Issue:5802

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Aminopyrine; Animals; Atropine; Benzimidazoles; Bucladesine; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Omeprazole; Potassium; Rabbits

1981
Differentiation among inhibitory actions of omeprazole, cimetidine, and SCN- on gastric acid secretion.
    The American journal of physiology, 1983, Volume: 245, Issue:1

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Benzimidazoles; Biological Transport; Cimetidine; Gastric Juice; Gastric Mucosa; Guanidines; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Histamine; Kinetics; Male; Microsomes; Omeprazole; Stomach; Thiocyanates

1983
Effect of omeprazole on gastric secretion in H+,K+-ATPase and in pepsinogen-rich cell fractions from rabbit gastric mucosa.
    Biochemical pharmacology, 1984, Jan-15, Volume: 33, Issue:2

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Atropine; Benzimidazoles; Cell Separation; Centrifugation, Density Gradient; Cimetidine; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; In Vitro Techniques; Male; Microsomes; Omeprazole; Pepsinogens; Rabbits

1984
Effects of omeprazole and cimetidine on gastric acid secretion and right atrial beating frequency in isolated organ preparations from the guinea pig.
    Digestion, 1984, Volume: 29, Issue:1

    Topics: Animals; Benzimidazoles; Bucladesine; Cimetidine; Gastric Acid; Gastric Mucosa; Guinea Pigs; Heart Atria; Heart Rate; Histamine; In Vitro Techniques; Male; Omeprazole; Stimulation, Chemical

1984
Duodenal ulcers that will not heal.
    Gut, 1984, Volume: 25, Issue:7

    Topics: Anti-Ulcer Agents; Benzimidazoles; Bismuth; Cimetidine; Drug Resistance; Duodenal Ulcer; Humans; Omeprazole; Organometallic Compounds; Ranitidine

1984
Ultrastructure of inhibited parietal cells in the rat.
    Gastroenterology, 1984, Volume: 87, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Atropine; Benzimidazoles; Cimetidine; Depression, Chemical; Gastric Acid; Gastric Mucosa; Male; Omeprazole; Rats; Rats, Inbred Strains; Surface Properties

1984
[Anti-ulcer agents. Clinico-experimental findings].
    Die Medizinische Welt, 1984, Feb-17, Volume: 35, Issue:7

    Topics: Antacids; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Cimetidine; Histamine Antagonists; Humans; Omeprazole; Peptic Ulcer; Pirenzepine; Prostaglandins, Synthetic

1984
Parietal cell structure during inhibition of acid secretion.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 101

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Cats; Cell Count; Cimetidine; Depression, Chemical; Dogs; Gastric Acid; Humans; Omeprazole; Parietal Cells, Gastric; Prostaglandins; Pyloric Antrum; Secretory Rate; Swine; Thiocyanates; Time Factors; Vagotomy; Vagus Nerve

1984
Inhibition of gastric acid secretion by omeprazole in the dog and rat.
    Gastroenterology, 1983, Volume: 85, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Benzimidazoles; Cimetidine; Dogs; Duodenum; Female; Gastric Acid; Injections, Intravenous; Male; Omeprazole; Rats; Rats, Inbred Strains; Vagotomy

1983
Hepatic glutathione after ethanol administration in rat: effects of cimetidine and omeprazole.
    Pharmacological research, 1995, Volume: 31, Issue:5

    Topics: Administration, Oral; Animals; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Glutathione; Liver; Male; Omeprazole; Rats; Rats, Wistar; Time Factors

1995
Control of gastric acid with high dose H2-receptor antagonists after omeprazole failure: report of two cases.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:10

    Topics: Adult; Anti-Ulcer Agents; Cimetidine; Drug Resistance; Female; Gastric Acid; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Male; Nizatidine; Omeprazole

1995
[Usefulness of every-other day administration of proton pump inhibitors from the standpoint of continuous 48-hour pH measurements-- Comparison of cimetidine, omeprazole, and lansoprazole].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1995, Volume: 92, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration; Lansoprazole; Male; Monitoring, Physiologic; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors

1995
[A case of chronic persistent cough caused by gastro-esophageal reflux].
    Nihon Kyobu Shikkan Gakkai zasshi, 1995, Volume: 33, Issue:6

    Topics: Aged; Chronic Disease; Cimetidine; Cough; Female; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Omeprazole; Proton Pump Inhibitors

1995
Antisecretory and antiulcer effects of YM020, a new H+,K(+)-ATPase inhibitor, in rats and dogs.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:1

    Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Histamine; Injections, Subcutaneous; Male; Omeprazole; Proton Pumps; Pyridines; Rats; Rats, Wistar; Ulcer

1995
Interaction between Helicobacter pylori and human gastric epithelial cells in culture: effect of antiulcer drugs.
    Pharmacology, 1994, Volume: 49, Issue:4

    Topics: Anti-Ulcer Agents; Bacterial Adhesion; Carcinoma; Cells, Cultured; Cimetidine; Duodenal Ulcer; Epithelial Attachment; Epithelial Cells; Epithelium; Gastric Mucosa; Gastritis; Gastrointestinal Neoplasms; Helicobacter Infections; Helicobacter pylori; Humans; Laryngeal Neoplasms; Microscopy, Phase-Contrast; Omeprazole; Organometallic Compounds; Tumor Cells, Cultured

1994
Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time.
    European journal of pharmacology, 1994, Oct-03, Volume: 263, Issue:3

    Topics: Acetates; Acetic Acid; Administration, Oral; Analysis of Variance; Animals; Atropine; Cimetidine; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Gastric Acid; Gastrins; Hydrogen-Ion Concentration; Male; Omeprazole; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Wound Healing

1994
Cimetidine and omeprazole accelerate gastric ulcer healing by an increase in gastrin secretion.
    European journal of pharmacology, 1994, Oct-03, Volume: 263, Issue:3

    Topics: Analysis of Variance; Animals; Cimetidine; Disease Models, Animal; Drug Interactions; Drug Synergism; Eating; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Male; Omeprazole; Oxidopamine; Pentagastrin; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Wound Healing

1994
Drug interactions of H2-receptor antagonists.
    Scandinavian journal of gastroenterology. Supplement, 1994, Volume: 206

    Topics: Adolescent; Adult; Aged; Antacids; Biological Availability; Cimetidine; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Middle Aged; Nizatidine; Omeprazole; Phenytoin; Ranitidine; Theophylline

1994
Validity of kissing gastric ulcers induced in rats for screening of antiulcer drugs.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Drug Evaluation, Preclinical; Gastric Acid; Male; Omeprazole; Rats; Stomach; Stomach Ulcer

1994
[Possibilities of the use of present-day antisecretory preparation omeprazole].
    Klinicheskaia meditsina, 1994, Volume: 72, Issue:6

    Topics: Adult; Aged; Aluminum Hydroxide; Antacids; Benzilates; Benzocaine; Choline; Cimetidine; Drug Combinations; Duodenal Ulcer; Humans; Magnesium Hydroxide; Omeprazole; Parasympatholytics; Peptic Ulcer; Time Factors; Zollinger-Ellison Syndrome

1994
Antisecretory effects of a novel and long-lasting histamine H2-receptor antagonist, YM-14471, in rats and dogs.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:3

    Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; Infusions, Intravenous; Male; Omeprazole; Pyrimidinones; Rats; Rats, Wistar; Thiazoles

1993
Effects of antisecretory agents on parietal cell structure and H/K-ATPase levels in rabbit gastric mucosa in vivo.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:10

    Topics: Animals; Blotting, Western; Cimetidine; Drug Interactions; Famotidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Male; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Rabbits

1994
The effects of omeprazole on the ultrastructure of gastric parietal cells.
    Journal of pediatric gastroenterology and nutrition, 1994, Volume: 19, Issue:1

    Topics: Child; Child, Preschool; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Female; Humans; Infant, Newborn; Male; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Stomach Ulcer; Vacuoles

1994
Effects of NC-1300-O-3 on gastric mucus secretion and prostaglandin release in rats.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Dinoprostone; Gastric Mucosa; Hexosamines; Hexoses; Indomethacin; Male; Mucus; Omeprazole; Prostaglandins; Rats; Rats, Sprague-Dawley

1994
Effect of omeprazole, an inhibitor of H+,K(+)-ATPase, on bone resorption in humans.
    Calcified tissue international, 1993, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Biomarkers; Body Weight; Bone Resorption; Calcium; Child; Cimetidine; Female; Histamine H2 Antagonists; Humans; Hydroxyproline; Male; Middle Aged; Omeprazole; Osteocalcin; Piperidines; Proton Pump Inhibitors; Stomach Ulcer

1993
Hepatitis following treatments with famotidine and then cimetidine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Famotidine; Fatty Liver; Female; Humans; Middle Aged; Omeprazole

1994
[Hemostasis and treatment of stress hemorrhage in the upper gastrointestinal tract of trauma patients].
    Acta medica Austriaca, 1993, Volume: 20, Issue:5

    Topics: Cimetidine; Combined Modality Therapy; Croatia; Endoscopy, Gastrointestinal; Gastrectomy; Humans; Military Personnel; Omeprazole; Peptic Ulcer Hemorrhage; Postoperative Complications; Ranitidine; Recurrence; Sclerotherapy; Stress, Physiological; Survival Rate; Suture Techniques; Vagotomy, Truncal; Warfare; Wounds, Gunshot

1993
Risk of gynaecomastia associated with cimetidine, omeprazole, and other antiulcer drugs.
    BMJ (Clinical research ed.), 1994, Feb-19, Volume: 308, Issue:6927

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Case-Control Studies; Cimetidine; Cohort Studies; Dose-Response Relationship, Drug; England; Gynecomastia; Humans; Male; Middle Aged; Omeprazole; Risk Factors; Time Factors

1994
Nonparallel secretion of pepsinogen and acid by gastric oxyntopeptic cells of the toad (Bufo marinus).
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Animals; Bufo marinus; Carbachol; Cimetidine; Colforsin; Esophagus; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Intestinal Mucosa; Kinetics; Microscopy, Electron; Mucous Membrane; Omeprazole; Parietal Cells, Gastric; Pepsin A; Pepsinogens; Time Factors

1993
[Study on omeprazole 20 mg twice weekly in prevention of duodenal ulcer relapse].
    Zhonghua nei ke za zhi, 1993, Volume: 32, Issue:8

    Topics: Adolescent; Adult; Aged; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Recurrence; Smoking

1993
Mechanism by which histamine increases gastric mucosal blood flow in the rat. Role of luminal H+.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:7

    Topics: Animals; Bicarbonates; Cimetidine; Drug Interactions; Gastric Acid; Gastric Mucosa; Glycine; Histamine; Hydrochloric Acid; Hydrogen; Indomethacin; Infusions, Intravenous; Male; Omeprazole; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium; Sodium Bicarbonate; Tripelennamine

1993
Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. Evidence for an aryl-hydrocarbon receptor-mediated mechanism.
    European journal of biochemistry, 1996, May-01, Volume: 237, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Base Sequence; Benzimidazoles; Benzoflavones; beta-Naphthoflavone; Binding Sites; Caco-2 Cells; Cell Differentiation; Cimetidine; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Humans; Kinetics; Lansoprazole; Molecular Sequence Data; Oligonucleotide Probes; Omeprazole; Receptors, Aryl Hydrocarbon; RNA, Messenger

1996
Peptic esophageal stricture: is surgery still necessary?
    Wiener klinische Wochenschrift, 1996, Volume: 108, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidine; Combined Modality Therapy; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Female; Follow-Up Studies; Fundoplication; Humans; Male; Middle Aged; Omeprazole; Ranitidine; Recurrence; Retrospective Studies; Survival Analysis; Treatment Outcome

1996
Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Atropine; Chronic Disease; Cimetidine; Duodenal Ulcer; Histamine; Male; Muscarinic Antagonists; Omeprazole; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1996
Nonsteroidal anti-inflammatory drug and phospholipid prodrugs: combination therapy with antisecretory agents in rats.
    Gastroenterology, 1996, Volume: 111, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Digestive System; Drug Therapy, Combination; Male; Omeprazole; Prodrugs; Ranitidine; Rats; Rats, Sprague-Dawley

1996
Effects of omeprazole and cimetidine on the urinary metabolic ratio of proguanil in healthy volunteers.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:5

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Male; Mixed Function Oxygenases; Omeprazole; Proguanil; Triazines

1996
Activity in the gastrointestinal tract after administration of bone-seeking radiopharmaceuticals. Experimental studies in mice.
    Acta radiologica (Stockholm, Sweden : 1987), 1996, Volume: 37, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Bone and Bones; Cimetidine; Digestive System; Diphosphonates; Male; Mice; Omeprazole; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Submandibular Gland; Technetium Tc 99m Medronate; Tissue Distribution

1996
Pentadecapeptide BPC 157, cimetidine, ranitidine, bromocriptine, and atropine effect in cysteamine lesions in totally gastrectromized rats: a model for cytoprotective studies.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Atropine; Bromocriptine; Cimetidine; Cysteamine; Duodenal Ulcer; Female; Gastrectomy; Omeprazole; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar

1997
Comparative study of plasma gastrin levels in rats after two months of ebrotidine administration.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Animals; Benzenesulfonates; Cimetidine; Gastrins; Histamine H2 Antagonists; Male; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiazoles

1997
Effects of cimetidine on acute gastric mucosal injury induced by ischemia-reperfusion in rats.
    Pharmacology, 1997, Volume: 55, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Erythrocyte Membrane; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Lipid Peroxidation; Male; Omeprazole; Rats; Rats, Wistar; Reperfusion Injury; Stomach Diseases

1997
Heart allograft rejection in rats triggered by H2 inhibitors.
    Transplantation proceedings, 1997, Volume: 29, Issue:7

    Topics: Animals; Antilymphocyte Serum; Cimetidine; Female; Graft Rejection; Graft Survival; Heart Transplantation; Histamine H2 Antagonists; Immunosuppressive Agents; Male; Omeprazole; Ranitidine; Rats; Rats, Inbred Strains; Transplantation, Homologous

1997
Omeprazole, H2 blockers, and polyarthralgia: case-control study.
    BMJ (Clinical research ed.), 1997, Nov-15, Volume: 315, Issue:7118

    Topics: Adult; Anti-Ulcer Agents; Arthralgia; Case-Control Studies; Cimetidine; Cohort Studies; Histamine H2 Antagonists; Humans; Middle Aged; Omeprazole; Ranitidine; Risk Factors

1997
H2-receptor antagonist reduces food intake and weight gain in rats by non-gastric acid secretory mechanisms.
    Acta physiologica Scandinavica, 1997, Volume: 161, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Eating; Famotidine; Gastric Acid; Histamine H2 Antagonists; Male; Omeprazole; Ranitidine; Rats; Rats, Wistar; Weight Gain

1997
Lansoprazole and ethanol metabolism: comparison with omeprazole and cimetidine.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alcohol Dehydrogenase; Animals; Anti-Ulcer Agents; Cimetidine; Enzyme Inhibitors; Ethanol; Glutathione; Humans; In Vitro Techniques; Lansoprazole; Liver; Male; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Wistar; Stomach

1997
The role of endogenous acid in the development of acute gastric ulcer induced by ischemia-reperfusion in the rat.
    Life sciences, 1998, Volume: 62, Issue:4

    Topics: Acute Disease; Animals; Anti-Ulcer Agents; Cimetidine; Gastric Acid; Gastric Mucosa; Ischemia; Male; Omeprazole; Rats; Rats, Wistar; Reperfusion Injury; Stomach; Stomach Ulcer

1998
Omeprazole in infants with cimetidine-resistant peptic esophagitis.
    The Journal of pediatrics, 1998, Volume: 132, Issue:2

    Topics: Anti-Ulcer Agents; Cimetidine; Esophagitis, Peptic; Histamine H2 Antagonists; Humans; Infant; Omeprazole; Treatment Failure; Treatment Outcome

1998
Omeprazole, ranitidine, and cimetidine have no effect on peak blood ethanol concentrations, first pass metabolism or area under the time-ethanol curve under 'real-life' drinking conditions.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:2

    Topics: Adult; Alcohol Drinking; Area Under Curve; Central Nervous System Depressants; Cimetidine; Ethanol; Female; Histamine H2 Antagonists; Humans; Male; Omeprazole; Ranitidine; Reference Values

1998
Anti-ulcer effects of antioxidants: effect of probucol.
    European journal of pharmacology, 1998, Aug-07, Volume: 354, Issue:2-3

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Ethanol; Free Radical Scavengers; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Hydroxyl Radical; Lipid Peroxidation; Male; Omeprazole; Probucol; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Superoxides; Thiobarbituric Acid Reactive Substances; Time Factors

1998
Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Atropine; Bucladesine; Calcium; Carbachol; Carcinogens; Cations; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; In Vitro Techniques; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Omeprazole; Potassium; Rabbits; Rotenone; Sodium; Stomach; Tetradecanoylphorbol Acetate; Uncoupling Agents; Vagus Nerve

1998
Antiulcer drug prescribing in hospital successfully influenced by "immediate concurrent feedback".
    Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:5

    Topics: Administration, Oral; Anti-Ulcer Agents; Cimetidine; Cost-Benefit Analysis; Drug Utilization; Famotidine; Feedback; Hong Kong; Hospitals, Teaching; Humans; Infusions, Intravenous; Medical Audit; Nizatidine; Omeprazole; Practice Patterns, Physicians'; Ranitidine

1998
Healing of cimetidine-resistant Ménétrier's disease by eradication of Helicobacter pylori infection.
    Journal of clinical gastroenterology, 1998, Volume: 27, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Cimetidine; Clarithromycin; Diterpenes; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Gastritis, Hypertrophic; Helicobacter Infections; Helicobacter pylori; Humans; Hypoproteinemia; Lansoprazole; Omeprazole; Time Factors

1998
Clinical and economic factors in the selection of drugs for gastroesophageal reflux disease.
    PharmacoEconomics, 1993, Volume: 3, Issue:2

    Topics: Cimetidine; Cost-Benefit Analysis; Endoscopy; Gastroesophageal Reflux; Humans; Omeprazole; Ranitidine; Treatment Outcome

1993
Symptomatic heterotopic gastric mucosa in the upper oesophagus.
    The Journal of laryngology and otology, 1998, Volume: 112, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Choristoma; Cimetidine; Esophageal Diseases; Esophagoscopy; Female; Gastric Mucosa; Humans; Lansoprazole; Male; Middle Aged; Omeprazole

1998
Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed.
    Epidemiology (Cambridge, Mass.), 1999, Volume: 10, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hospitalization; Humans; Incidence; Male; Middle Aged; Omeprazole; Peptic Ulcer; Ranitidine; Risk Factors; Secondary Prevention

1999
Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:4

    Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catalase; Cimetidine; Diterpenes; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Leukocyte Count; Male; Neutrophils; Omeprazole; Perfusion; Quinolones; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase

1999
Use of cimetidine, omeprazole, and ranitidine in pregnant women and pregnancy outcomes.
    American journal of epidemiology, 1999, Sep-01, Volume: 150, Issue:5

    Topics: Abnormalities, Drug-Induced; Anti-Ulcer Agents; Cimetidine; Cohort Studies; Female; Humans; Infant, Newborn; Italy; Omeprazole; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Ranitidine; Risk; United Kingdom

1999
Determination of the human cytochrome P450 isoforms involved in the metabolism of zolmitriptan.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8

    Topics: Cimetidine; Clorgyline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Liver; Male; Microsomes, Liver; Omeprazole; Oxazoles; Oxazolidinones; Recombinant Proteins; Serotonin Receptor Agonists; Theophylline; Tryptamines

1999
In vitro metabolism and interaction of cilostazol with human hepatic cytochrome P450 isoforms.
    Human & experimental toxicology, 2000, Volume: 19, Issue:3

    Topics: Chromatography, High Pressure Liquid; Cilostazol; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Felodipine; Humans; In Vitro Techniques; Isoenzymes; Ketoconazole; Microsomes, Liver; Omeprazole; Platelet Aggregation Inhibitors; Tetrazoles

2000
NH(4)Cl inhibition of acid secretion: possible involvement of an apical K(+) channel in bullfrog oxyntic cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Ammonia; Ammonium Chloride; Animals; Barium; Biological Transport; Bumetanide; Carbachol; Carbon Radioisotopes; Cholinergic Agents; Cimetidine; Clotrimazole; Diuretics; Enzyme Inhibitors; Gastric Mucosa; Growth Inhibitors; Histamine; Hydrochloric Acid; Hypoglycemic Agents; Imidazoles; Methylamines; Microscopy, Electron; Omeprazole; Ouabain; Parietal Cells, Gastric; Potassium Channel Blockers; Potassium Channels; Protons; Rana catesbeiana; Tetraethylammonium; Tolbutamide

2000
Strategies for reducing the prescribing of proton pump inhibitors (PPIs): patient self-regulation of treatment may be an under-exploited resource.
    Social science & medicine (1982), 2000, Volume: 51, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidine; Drug Utilization; Economics, Pharmaceutical; England; Family Practice; Humans; Middle Aged; Omeprazole; Patients; Physician-Patient Relations; Practice Patterns, Physicians'; Proton Pump Inhibitors

2000
The prescribing of acid suppressants prior to the endoscopic diagnosis of Barrett's oesophagus and oesophagitis.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: Antacids; Barrett Esophagus; Cimetidine; Drug Prescriptions; Endoscopy; Esophagitis; Female; Humans; Male; Middle Aged; Omeprazole; Practice Patterns, Physicians'; Ranitidine

2001
Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.
    Life sciences, 2001, Mar-09, Volume: 68, Issue:16

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bromocriptine; Cimetidine; Disease Models, Animal; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Indomethacin; Lansoprazole; Male; Mice; Mice, Inbred Strains; Misoprostol; Omeprazole; Pantoprazole; Peptide Fragments; Proteins; Ranitidine; Stomach Diseases; Sulfoxides

2001
Gastroprotective effect of aparisthman, a diterpene isolated from Aparisthmium cordatum, on experimental gastric ulcer models in rats and mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2001, Volume: 8, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Brazil; Cimetidine; Disease Models, Animal; Diterpenes; Euphorbiaceae; Female; Gastric Acid; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Indomethacin; Lansoprazole; Male; Mice; Omeprazole; Peptic Ulcer; Plant Extracts; Rats; Rats, Wistar; Trees

2001
Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole.
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:1

    Topics: Anti-Ulcer Agents; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Male; Microsomes, Liver; Nizatidine; Omeprazole; Pharmaceutical Preparations

2001
The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion.
    The Journal of biological chemistry, 2001, Oct-26, Volume: 276, Issue:43

    Topics: Animals; Anti-Ulcer Agents; Calcium; Cations, Divalent; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Histamine H2 Antagonists; Magnesium; Omeprazole; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Receptors, Cell Surface

2001
The influence of commonly prescribed synthetic drugs for peptic ulcer on the pharmacokinetic fate of glycyrrhizin from Shaoyao-Gancao-tang.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:12

    Topics: Amoxicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Area Under Curve; Butylscopolammonium Bromide; Chromatography, High Pressure Liquid; Cimetidine; Drug Combinations; Drug Therapy, Combination; Drugs, Chinese Herbal; Feces; Glycyrrhiza; Glycyrrhizic Acid; Hydrolysis; Male; Metronidazole; Muscarinic Antagonists; Omeprazole; Paeonia; Peptic Ulcer; Phytotherapy; Rats; Rats, Wistar

2001
Vitamin B(12) deficiency associated with histamine(2)-receptor antagonists and a proton-pump inhibitor.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5

    Topics: Aged; Cimetidine; Creatinine; Enzyme Inhibitors; Female; Folic Acid; Gastroesophageal Reflux; Histamine H2 Antagonists; Homocysteine; Humans; Methylmalonic Acid; Omeprazole; Proton Pump Inhibitors; Vitamin B 12; Vitamin B 12 Deficiency

2002
Anti-ulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Brazil; Cimetidine; Cucurbitaceae; Ethanol; Female; Flavonoids; Gastric Mucosa; Indomethacin; Male; Mice; Morphine; Motor Activity; Omeprazole; Phytotherapy; Plant Extracts; Rats; Stomach Ulcer; Tail; Toxicity Tests, Acute

2002
Influence of aging on gastric ulcer healing activities of cimetidine and omeprazole.
    European journal of pharmacology, 2002, May-31, Volume: 444, Issue:3

    Topics: Aging; Animals; Cimetidine; Gastrins; Male; Omeprazole; Rats; Rats, Wistar; Stomach Ulcer

2002
Sodium pentobarbital anesthesia transiently enhances the severity of infection following intragastric, but not intravenous, inoculation of Listeria monocytogenes in mice.
    Microbial pathogenesis, 2003, Volume: 35, Issue:2

    Topics: Anesthesia; Animals; Anti-Ulcer Agents; Antidiarrheals; Cell Culture Techniques; Cell Line; Cimetidine; Colony Count, Microbial; Gastrointestinal Diseases; Humans; Hypnotics and Sedatives; Immunity, Innate; Listeria monocytogenes; Listeriosis; Liver; Loperamide; Mice; Omeprazole; Pentobarbital; Spleen

2003
[Pharmacotherapy in complex treatment of ulcerous stenosis].
    Vestnik khirurgii imeni I. I. Grekova, 2003, Volume: 162, Issue:3

    Topics: Amoxicillin; Antacids; Anti-Infective Agents; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; Duodenal Ulcer; Enzyme Inhibitors; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Metronidazole; Omeprazole; Pyloric Stenosis; Ranitidine; Time Factors

2003
Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biopsy; Child; Cimetidine; Diagnosis, Differential; Enzyme Inhibitors; Eosinophilia; Esophagitis; Esophagoscopy; Esophagus; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Lansoprazole; Male; Omeprazole; Prednisone

2004
Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Bethanechol; Cimetidine; Disease Models, Animal; Eriocaulaceae; Ethanol; Gastric Juice; Gastrointestinal Contents; Hydrogen-Ion Concentration; Indomethacin; Lansoprazole; Male; Mice; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological

2004
Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube.
    International journal of clinical pharmacology and therapeutics, 2004, Volume: 42, Issue:11

    Topics: Adolescent; Antacids; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; Gastroesophageal Reflux; Hemorrhage; Humans; Intubation, Gastrointestinal; Male; Omeprazole; Proton Pump Inhibitors; Stomach Diseases

2004
Ischemia of rat stomach mobilizes ECL cell histamine.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:5

    Topics: Animals; Cimetidine; Enterochromaffin-like Cells; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Ischemia; Male; Mast Cells; Methylhistidines; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Wistar; Reperfusion Injury

2005
Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: consequences for FK506 assimilation.
    Kidney international, 2005, Volume: 67, Issue:3

    Topics: Adult; Aged; Anti-Ulcer Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cimetidine; Cohort Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Gastric Acid; Humans; Kidney Transplantation; Male; Middle Aged; Omeprazole; Tacrolimus

2005
The effect of pharmacologically altered gastric pH on cadmium absorption from the diet and its accumulation in murine tissues.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2005, Volume: 43, Issue:5

    Topics: Absorption; Animals; Biological Availability; Cadmium; Cimetidine; Diet; Enzyme Inhibitors; Female; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Kidney; Liver; Male; Mice; Omeprazole; Organ Specificity; Random Allocation; Solubility; Testis; Tissue Distribution

2005
Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Allergens; Animals; Benzimidazoles; Bronchi; Bronchoalveolar Lavage Fluid; Capsaicin; Cimetidine; Cough; Dose-Response Relationship, Drug; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Immunohistochemistry; Irritants; Omeprazole; Ovalbumin; Proton Pump Inhibitors; Rabeprazole; Trachea

2005
L-type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 289, Issue:4

    Topics: Amino Acids; Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Gastric Acid; Gastric Acidity Determination; H(+)-K(+)-Exchanging ATPase; Male; Mice; Omeprazole; Parietal Cells, Gastric; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Stimulation, Chemical; Tryptophan

2005
Effect of Cimetidine and Phenobarbital on metabolite kinetics of Omeprazole in rats.
    Archives of pharmacal research, 2005, Volume: 28, Issue:10

    Topics: Algorithms; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Injections, Intraperitoneal; Injections, Intravenous; Male; Models, Biological; Omeprazole; Phenobarbital; Rats; Rats, Sprague-Dawley; Time Factors

2005
An amino acid transporter involved in gastric acid secretion.
    Pflugers Archiv : European journal of physiology, 2006, Volume: 451, Issue:6

    Topics: Action Potentials; Amino Acid Transport Systems; Amino Acids; Amino Acids, Cyclic; Animals; Calcium; Cimetidine; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Hydrogen-Ion Concentration; Male; Omeprazole; Parietal Cells, Gastric; Proton Pump Inhibitors; Protons; Rats; Rats, Wistar

2006
Histamine signaling through the H(2) receptor in the Peyer's patch is important for controlling Yersinia enterocolitica infection.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Jun-13, Volume: 103, Issue:24

    Topics: Animals; Anti-Allergic Agents; Anti-Ulcer Agents; Cimetidine; Dimaprit; Female; Gene Expression Profiling; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Omeprazole; Peyer's Patches; Pyrilamine; Receptors, Histamine H2; Signal Transduction; Survival Rate; Yersinia enterocolitica; Yersinia Infections

2006
Effect of acid secretion blockade on acute gastric mucosal lesions induced by Tityus serrulatus scorpion toxin in anaesthetized rats.
    Toxicon : official journal of the International Society on Toxinology, 2006, Volume: 48, Issue:5

    Topics: Acute Disease; Anesthesia; Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Gastrointestinal Agents; Male; Neurotoxins; Octreotide; Omeprazole; Pepsin A; Ranitidine; Rats; Scorpion Venoms; Stomach Diseases

2006
Pathogenic importance of pepsin in ischemia/reperfusion-induced gastric injury.
    Life sciences, 2007, May-01, Volume: 80, Issue:21

    Topics: Animals; Anti-Ulcer Agents; Atropine; Cimetidine; Dose-Response Relationship, Drug; Male; Omeprazole; Pepsin A; Pepstatins; Pylorus; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2007
Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Baccharis; Brazil; Chromatography, High Pressure Liquid; Cimetidine; Cinnamates; Dose-Response Relationship, Drug; Flavonoids; Gastric Acidity Determination; Gastric Juice; Hydrogen-Ion Concentration; Male; Omeprazole; Plant Extracts; Plant Leaves; Plants, Medicinal; Propolis; Rats; Rats, Wistar; Stomach Ulcer

2007
Evaluation of the antiulcerogenic activity of Maytenus robusta (Celastraceae) in different experimental ulcer models.
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Brazil; Cimetidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gastric Acid; Gastric Acidity Determination; Hydrogen-Ion Concentration; Indomethacin; Male; Maytenus; Omeprazole; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Severity of Illness Index; Stomach Ulcer

2007
[Stress ulcer prophylaxis in septic patients. Evidence-based overview].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2008, Volume: 43, Issue:5

    Topics: Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Evidence-Based Medicine; Gastric Acid; Gastrointestinal Hemorrhage; Humans; Omeprazole; Peptic Ulcer Hemorrhage; Sepsis; Shock, Septic; Stomach Ulcer; Stress, Psychological

2008
Validation of a conscious rat model for the discovery of novel agents that inhibit gastric acid secretion.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Administration, Oral; Animals; Cimetidine; Consciousness; Dimaprit; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastrointestinal Agents; Histamine H2 Antagonists; Imidazoles; Ligation; Male; Models, Animal; Omeprazole; Pentagastrin; Proton Pump Inhibitors; Pyridines; Rats; Rats, Wistar; Reproducibility of Results; Stomach; Suction

2008
Phytochemical analyses and gastroprotective effects of Eugenia umbelliflora (Myrtaceae) on experimental gastric ulcers.
    Natural product communications, 2009, Volume: 4, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Central Nervous System Depressants; Cholinergic Agents; Chromatography, Thin Layer; Cimetidine; Cold Temperature; Ethanol; Fruit; Indomethacin; Male; Mice; Mice, Inbred BALB C; Omeprazole; Plant Extracts; Plant Leaves; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Syzygium

2009
Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25 Suppl 1

    Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Capsaicin; Cimetidine; Disease Models, Animal; Enterobacteriaceae; Famotidine; Histamine H2 Antagonists; Intestinal Mucosa; Intestine, Small; Male; Mucin-2; Nitric Oxide Synthase Type II; Omeprazole; Peptic Ulcer; Peroxidase; Phenylpropionates; Piperidines; Proton Pump Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sensory Receptor Cells

2010
Warfarin therapy: how the less interesting half just got interesting.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:12

    Topics: Acetaminophen; Anticoagulants; Azithromycin; Cimetidine; Cytochrome P-450 Enzyme System; Drug Interactions; Gefitinib; Humans; Omeprazole; Quinazolines; Stereoisomerism; Substrate Specificity; Warfarin

2010
In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins.
    Acta dermato-venereologica, 2012, Volume: 92, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ascorbic Acid; Cimetidine; Erythrocytes; Famotidine; Hemolysis; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lansoprazole; Lovastatin; Nizatidine; Omeprazole; Pantoprazole; Pravastatin; Proton Pump Inhibitors; Ranitidine; Ultraviolet Rays

2012
Disposition of the anti-ulcer medications ranitidine, cimetidine, and omeprazole following administration of multiple doses to exercised Thoroughbred horses.
    Journal of veterinary pharmacology and therapeutics, 2017, Volume: 40, Issue:1

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Female; Half-Life; Horses; Male; Omeprazole; Physical Conditioning, Animal; Ranitidine

2017
Comparison of the toxicity of sulfur mustard and its oxidation products in vitro.
    Toxicology letters, 2020, Mar-15, Volume: 321

    Topics: Antidotes; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Mustard Gas; Nerve Agents; Omeprazole; Oxidation-Reduction; Sulfones; Sulfoxides

2020