omeprazole and aspirin

omeprazole has been researched along with aspirin in 169 studies

Research

Studies (169)

TimeframeStudies, this research(%)All Research%
pre-199011 (6.51)18.7374
1990's18 (10.65)18.2507
2000's62 (36.69)29.6817
2010's68 (40.24)24.3611
2020's10 (5.92)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bergmann, JF; Caulin, C; Chassany, O; Lemaire, M; Segrestaa, JM; Simoneau, G1
Koop, H1
Bright, RM; DeNovo, RC; Jenkins, CC; Patton, CS; Rohrbach, BW1
Bhaskar, NK; Daneshmend, TK; Hawkey, CJ; Stein, AG1
Niida, H; Nishiwaki, H; Okabe, S; Takeuchi, K1
Okabe, S1
Hara, K; Higaki, E; Higuchi, T; Okabe, S; Sato, M1
Bigard, MA1
Dammann, HG; Müller, P; Simon, B2
Gilbertson, SK; Kolbasa, KP; Lancaster, C; Olafsson, AS; Robert, A1
Jourdan, MH; Mason, RC; Rowe, PH1
Carter, DC; Salim, AS; Utley, RJ1
Brzozowski, T; Konturek, SJ; Radecki, T1
Andersson, K; Larsson, H; Mattsson, H1
Okabe, S; Okada, Y; Yamamoto, O1
Elsner, H; Müller, P; Simon, B1
Kamishiro, T; Kawaguchi, K; Masuda, M; Matsukura, H; Uchida, A1
Behler, EM; Elta, GH; Loeffler, KM; Scheiman, JM1
Diwan, PV; Krishna, DR; Sastry, MS1
Coffey, RJ; Greenson, JK; Meise, KS; Scheiman, JM1
Fuchs, W; Müller, P; Simon, B1
Dial, EJ; Felder, TB; Giraud, MN; Illich, PA; Lichtenberger, LM; Sanduja, SK1
Endo, T; Nagasaki, M; Noto, T; Yomota, E1
Müller, P; Simon, B1
Ayanoglu-Dülger, G; Imeryüz, N; Nefesoglu, FZ; Ulusoy, NB1
Akiba, Y; Kaunitz, JD; Tanaka, S1
Bertaccini, G; Coppelli, G; Coruzzi, G; Frati, P1
Harewood, G1
Cornudella, R; Esteva, F; Iñarrea, P; Lanas, A1
Fujita, A; Takeuchi, K; Tashima, K; Umeda, M1
Denaro, MG; Faggio, C; Lionetto, MG; Trischitta, F1
Cheon, HG; Lee, DH; Lee, SS; Lim, H1
Lanas, AI1
Chan, FK; Chan, HL; Chung, SC; Hui, Y; Lai, MS; Lau, JY; Lee, YT; Leung, VK; Leung, WK; Suen, BY; Sung, JJ; Wu, JC1
Arbak, S; Ayanoğlu-Dülger, G; Hürdağ, C; Paskaloğlu, K; Sener-Muratoğlu, G1
Boknik, P; Domschke, W; Fischer, H; Huber, V; Konturek, JW; Luess, H; Neumann, J; Schmitz, W1
Jacobson, BC1
McCarthy, DM1
Astudillo, L; Bustamante, C; Rodríguez, JA; Schmeda-Hirschmann, G1
Di Stasi, LC; Gonzalez, FG1
Astudillo, L; Rodriguez, JA; Schmeda-Hirschmann, G1
Chan, AO; Chu, KM; Hu, WH; Hui, WM; Lai, CL; Lai, KC; Lam, SK; Lau, GK; Wong, BC; Wong, J; Wong, WM; Yuen, MF1
Fernández-Fernández, FJ1
Harris, AW; Maiden, LP1
Guda, N; Vakil, N1
Wepner, U1
Nelson, DB; Sawhney, MS1
Jansen, JB; Laheij, RJ; Van Rossum, LG; Verheugt, FW1
Bajador, E; Cabrol, J; Cucala, M; Gomollón, F; Lanas, A; Lorente, S; Márquez, JL; Montoro, M; Nuevo, J; Pérez-Roldan, F; Quintero, E; Rodrigo, L; Santolaria, S1
Ferrández, A; Lanas, A1
Füessl, HS1
Laine, L1
Chang, CM; Chen, WH; Ng, FH; Wong, BC; Wong, SY1
Jankowski, J; Moayyedi, P1
Singh, G1
Celikel, CA; Giral, A; Kalayci, C; Ozdogan, O; Tozun, N; Ulusoy, NB1
Kotaira, J1
Cryer, B2
D'Ambrosio, LP; Franceschi, M; Leandro, G; Longoa, MG; Orsitto, G; Perri, FC; Pilotto, A; Scarcelli, C1
Amer, F; Christopoulos, NG; Goldstein, JL; Huang, B1
Arkkila, PE; Färkkilä, M; Kosunen, TU; Mäkinen, J; Rautelin, H; Seppälä, K; Sipponen, P1
Chiou, CF; Ofman, JJ; Spiegel, BM1
Cho, YK; Jeon, WK; Keum, DK; Kim, BI; Kim, HJ; Kim, SH; Park, DI; Park, SH; Sohn, CI; Sung, IK1
Dharmani, P; Maurya, R; Mishra, PK; Palit, G; Singh Chauhan, V1
Chauhan, VS; Dharmani, P; Maurya, R; Mishra, PK; Palit, G1
Hull, R; Marshall, RW; Marshall, VJ1
Agustí-Escasany, A; Vallano-Ferraz, A1
Go, MF1
Hu, FL; Ji, KY1
Abgrall, JF; Arnaud, B; Boschat, J; Gilard, M; Le Gal, G1
Gopalakrishnan, G; Kavimani, S; Malairajan, P; Narasimhan, S; Veni, KJ1
Bayan, K; Canoruç, F; Daniş, R; Dursun, M; Ertem, M; Kilinç, N; Tüzün, Y; Yilmaz, S1
Arnesen, Ø; Riis, JS1
Huntoon, MA; Watson, JC1
Matsuda, H; Nagatomo, A; Ochi, M; Yoshikawa, M1
Dregelid, E1
Díte, P; Kunovská, M; Münzová, H; Novotný, I1
Bobb, A; Bulsiewicz, W; Christensen, K; Coté, GA; Howden, CW; Norvell, JP; Postelnick, M; Rice, JP1
Ferringer, T; Lountzis, NI; Puri, PK; Tyler, W1
Goto, S; Serebruany, V1
Braun, S; Hadamitzky, M; Kastrati, A; Morath, T; Schömig, A; Sibbing, D; Stegherr, J; Vogt, W; von Beckerath, N1
Attwood, S; Barr, H; deCaestecker, J; Jankowski, J1
Bretagne, JF1
Herszényi, L; Juhász, M; Tulassay, Z1
Börgel, J; Endres, HG; Engelhardt, A; Krüger, JC; Lask, S; Mügge, A; Neubauer, H1
Nathisuwan, S; Panomvana, D; Sansanayudh, N; Siriswangvat, S1
Morini, S; Zullo, A1
Bhatt, DL; Cannon, CP; Cohen, M; Contant, CF; Cryer, BL; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Murphy, SA; Schnitzer, TJ; Scirica, BM; Shook, TL1
Grad, Y; Ross, JJ; Schaffer, AC1
Kandulski, A; Malfertheiner, P; Venerito, M1
Cai, J; Fan, L; Liu, CF; Sun, J; Wang, ZG; Wu, Q1
Grad, YH; Levy, BD; Loscalzo, J; Seifter, JL1
Danikiewicz, A; Hudzik, B; Lekston, A; Polonski, L; Romanowski, W; Szkodzinski, J; Wilczek, K; Zubelewicz-Szkodzinska, B1
Jobe, BA; Lombard, CM; Triadafilopoulos, G1
Lanas, A; Sostres, C1
Vassiliou, V1
Dev, K; Maurya, R; Palit, G; Sahai, M; Sharma, R; Singh, N; Yadav, DK1
Hiraishi, H; Kanke, K; Maeda, M; Sasai, T; Shimada, T1
Chen, JS; Chen, L; Chen, YD; Guo, YS; Huang, TT; Liu, HB; Ren, YH; Sun, ZJ; Wang, CY; Wang, Y; Xie, YJ; Zhao, M1
Abe, Y; Endo, H; Higurashi, T; Hosono, K; Iida, H; Inamori, M; Koide, T; Nakajima, A; Sakai, E; Sakamoto, Y; Sekino, Y; Takahashi, H; Tokoro, C; Yoneda, M1
Yeomans, ND1
Chen, PF; Hsiao, FY; Huang, WF; Mullins, CD; Tsai, YW; Wen, YW1
Antonino, M; Bliden, KP; Fort, J; Gesheff, M; Gurbel, PA; Plachetka, JR; Tantry, US; Zhang, Y1
Harrison, RW; Mahaffey, KW1
Abe, T; Fujioka, T; Inoue, K; Kodama, M; Mizukami, K; Murakami, K; Okimoto, T; Uchida, M1
Abdelwahab, SI; Abdulla, MA; Ali, HM; Hadi, AH; Salga, MS; Taha, MM1
Hashimoto, E; Izuhara, C; Kaneko, S; Takayama, S; Takeuchi, K; Yamada, N; Yamanaka, S1
Horiuchi, H; Ikeda, T; Imai, M; Jinnai, T; Kato, Y; Kimura, T; Makiyama, T; Shirakawa, R; Tada, T; Tazaki, J; Yamane, K1
Blackler, R; Bolla, M; Ongini, E; Syer, S; Wallace, JL1
Geetha, A; Megala, J1
Endo, T; Fukui, K; Hibi, K; Himeno, H; Kimura, K; Morita, S; Sugano, T; Tsukahara, K; Umemura, S; Yano, H1
Abd-Elmageid, SA; Alshailabi, EM; El-Shinnawy, NA1
Inadomi, JM1
Horiuchi, H1
Chen, YF; Dang, DS; Liu, Q; Shi, GB; Yan, M; Zhao, QC1
Antonino, M; Bliden, KP; Chai, S; Fort, JG; Gesheff, M; Gesheff, T; Gurbel, PA; Jeong, YH; Shuldiner, A; Tantry, US; Zhang, Y1
Agrawal, M; Madhur, G; Mishra, V; Narender, T; Onasanwo, SA; Palit, G; Pandey, HP; Rastogi, P1
Cutfield, NI; Tong, DC1
Brickl, R; Ehrlich, J; Eisert, W; Offman, E; Schobelock, MJ; VanderMaelen, CP1
Abramowitz, Y; Arbel, Y; Banai, S; Berliner, S; Birati, EY; Deutsch, V; Finkelstein, A; Halkin, A; Herz, I; Keren, G; Kletzel, H1
Fort, JG; Miner, PB; Zhang, Y1
Barthwal, MK; Khaliq, T; Mishra, V; Narender, T; Palit, G; Pandey, HP; Singh, VK; Tiwari, S1
Labenz, J1
Bliden, KP; Brener, M; Franzese, CJ; Gesheff, MG; Gurbel, PA; Tabrizchi, A; Tantry, U1
Chen, G; Du, Y; Hang, L; Ma, B1
Andersson, T; Galbraith, H; Nagy, P; Niazi, M; Nylander, S; Ranjan, S; Wallentin, L1
Cryer, BL; Eisen, GM; Fort, JG; Goldstein, JL; Lanas, A; Miller, AB; O'Connor, C; Scheiman, JM; Whellan, DJ; Zhang, Y1
Chan, HH; Chen, WC; Cheng, JS; Chiang, PH; Lai, KH; Li, YD; Tsai, TJ; Tsai, WL; Tsay, FW; Wang, EM1
Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M1
Ali, A; Aslam, B; Javed, I; Khaliq, T; Majeed, W; Muhammad, F; Raza, A1
Cryer, BL; Eisen, GM; Fort, JG; Goldstein, JL; Lanas, A; Scheiman, JM; Whellan, DJ1
Mitrov-Winkelmolen, L; Overdiek, HWPM; Swank, DJ; Touw, DJ; van Buul-Gast, MW; van Schaik, RHN1
Fort, JG; Goldstein, JL; Scheiman, JM; Whellan, DJ1
Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Hsieh, WH; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; Schnitzer, TJ; Shook, TL; Vaduganathan, M2
Farkouh, ME1
Bliden, K; Chaudhary, R; Gurbel, PA; Sharma, T; Tantry, U1
Fort, JG; Han, Y; Schofield, D; Tursi, JP; Zhang, W1
García-Rayado, G; Lanas, A; Sostres, C1
Bridgeman, MB; Dalal, KS1
Haseeb, S; Kagolanu, D; Lam, P; Munnangi, S; Sayedy, N; Shah, S; Stephenson, K; Viswanathan, P1
Patel, AD; Patel, VB; Shah, DA1
Bravo-Gutiérrez, A; García-Romera, Á; González-Delgado, C; González-Hernández, S; Soto-Darias, I1
Abdelaleem, EA; Abdelhamid, NS; Abou El Ella, DA; Mahmoud, AM1
Chen, WC; Cheng, JS; Chuah, SK; Hsu, PI; Kao, SS; Peng, NJ; Shie, CB; Tang, SY; Tsai, KF; Tsay, FW; Tseng, ZF1
Ghasemkhani, N; Namazi, F; Nazifi, S; Tabrizi, AS1
Abdelazim, AH; Almrasy, AA; El-Olemy, A; Hasan, MA; Madkour, AW; Ramzy, S; Shahin, M1
Badrawy, M; El-Mammli, MY; Elmasry, MS; Hassan, WS; Serag, A1
Badrawy, M; El-Mammli, MY; Elmasry, MS; Hassan, WS1
Affuso, F; Bellavite, P; Fazio, S; McCullough, PA; Pandolfi, S; Zanolin, E1
Beloosesky, Y; Boltin, D; Gingold-Belfer, R; Issa, N; Koren-Morag, N; Meyerovitch, J; Peleg, N; Schmilovitz-Weiss, H; Sharon, E1

Reviews

19 review(s) available for omeprazole and aspirin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Effects of gastric proton pump inhibitors on gastric secretion and peptic ulcers].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Bucladesine; Dogs; Duodenal Ulcer; Ethanol; Gastric Juice; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine H2 Antagonists; Humans; Mice; Omeprazole; Parietal Cells, Gastric; Rats; Stomach Ulcer; Structure-Activity Relationship

1986
Prevention and treatment of gastrointestinal symptoms and complications due to NSAIDs.
    Best practice & research. Clinical gastroenterology, 2001, Volume: 15, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastrointestinal Diseases; Histamine H2 Antagonists; Humans; Misoprostol; Omeprazole; Risk Factors; Sucralfate

2001
Treatment and prevention of aspirin-induced gastroduodenal ulcers and gastrointestinal bleeding.
    Expert opinion on drug safety, 2002, Volume: 1, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Helicobacter pylori; Humans; Omeprazole; Peptic Ulcer; Randomized Controlled Trials as Topic

2002
The role of proton pump inhibitors in NSAID-associated gastropathy and upper gastrointestinal symptoms.
    Reviews in gastroenterological disorders, 2003, Volume: 3 Suppl 4

    Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dyspepsia; Humans; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Randomized Controlled Trials as Topic

2003
Understanding NSAID-PPI-COX-2 interrelationships.
    Drugs of today (Barcelona, Spain : 1998), 2004, Volume: 40 Suppl A

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Cyclooxygenase Inhibitors; Gastroesophageal Reflux; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Sulfoxides

2004
Minimizing complications from nonsteroidal antiinflammatory drugs: cost-effectiveness of competing strategies in varying risk groups.
    Arthritis and rheumatism, 2005, Apr-15, Volume: 53, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Cost-Benefit Analysis; Drug Therapy, Combination; Gastrointestinal Diseases; Humans; Lactones; Lansoprazole; Naproxen; Omeprazole; Proton Pump Inhibitors; Pyrazoles; Rheumatology; Sulfonamides; Sulfones

2005
Interaction or relationship between Helicobacter pylori and non-steroidal anti-inflammatory drugs in upper gastrointestinal diseases.
    World journal of gastroenterology, 2006, Jun-28, Volume: 12, Issue:24

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dyspepsia; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Peptic Ulcer; Rheumatic Diseases; Risk Factors

2006
[Prevention of GI bleeding due to antiplatelet agents: a labyrinth!].
    Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Lansoprazole; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine

2009
Current standings of the proton pump inhibitor and clopidogrel co-therapy: review on an evolving field with the eyes of the gastroenterologist.
    Digestion, 2010, Volume: 81, Issue:1

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastroenterology; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Ticlopidine

2010
[Dilemma between gastroprotection and cardiovascular prevention].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:44

    Topics: Alleles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Long-Term Care; Mutation; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Survival Analysis; Ticlopidine; Treatment Outcome

2010
[Strategy to manage low dose aspirin-induced gastrointestinal injury].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:2

    Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Famotidine; Gastric Mucosa; Humans; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Proton Pump Inhibitors; Ticlopidine

2011
Reducing the risk of gastroduodenal ulcers with a fixed combination of esomeprazole and low-dose acetyl salicylic acid.
    Expert review of gastroenterology & hepatology, 2011, Volume: 5, Issue:4

    Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Drug Therapy, Combination; Esomeprazole; Humans; Omeprazole; Peptic Ulcer; Randomized Controlled Trials as Topic; Risk

2011
Clopidogrel and PPI interaction: clinically relevant or not?
    Current cardiology reports, 2012, Volume: 14, Issue:1

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Thienopyridines; Ticlopidine

2012
PA tablets: investigational compounds combining aspirin and omeprazole for cardioprotection.
    Future cardiology, 2013, Volume: 9, Issue:6

    Topics: Administration, Oral; Aspirin; Biological Availability; Cardiovascular Diseases; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Tablets

2013
Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Secondary Prevention

2017
Yosprala - a combination of aspirin and omeprazole.
    The Medical letter on drugs and therapeutics, 2017, Jan-30, Volume: 59, Issue:1513

    Topics: Animals; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Humans; Omeprazole

2017
Aspirin and omeprazole for secondary prevention of cardiovascular disease in patients at risk for aspirin-associated gastric ulcers.
    Expert review of clinical pharmacology, 2017, Volume: 10, Issue:8

    Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Secondary Prevention; Stomach Ulcer

2017
Usefulness of PA32540 in Protecting the Gastric Layer While Providing Secondary Prevention for Coronary Artery Disease.
    The American journal of cardiology, 2017, Oct-01, Volume: 120, Issue:7

    Topics: Administration, Oral; Aspirin; Coronary Artery Disease; Double-Blind Method; Drug Combinations; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention

2017

Trials

49 trial(s) available for omeprazole and aspirin

ArticleYear
Protection against aspirin-induced gastric lesions by lansoprazole: simultaneous evaluation of functional and morphologic responses.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Analysis of Variance; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Female; Gastric Mucosa; Gastroscopy; Humans; Lansoprazole; Male; Membrane Potentials; Omeprazole; Reference Values; Stomach Ulcer

1992
Abolition by omeprazole of aspirin induced gastric mucosal injury in man.
    Gut, 1990, Volume: 31, Issue:5

    Topics: Adult; Aspirin; Double-Blind Method; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Omeprazole; Randomized Controlled Trials as Topic

1990
[Protective effect of omeprazole on gastric lesions induced by a single dose of aspirin in man].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:10

    Topics: Aspirin; Clinical Trials as Topic; Double-Blind Method; Gastric Mucosa; Humans; Male; Omeprazole

1988
[Acute injury to the gastric mucosa by acetylsalicylic acid. A comparative endoscopic study in man with oral prostaglandin analogs, omeprazole and ranitidine].
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:2

    Topics: Adult; Alprostadil; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Clinical Trials as Topic; Double-Blind Method; Gastric Mucosa; Gastroscopy; Humans; Misoprostol; Omeprazole; Prostaglandins E; Prostaglandins, Synthetic; Random Allocation; Ranitidine; Rioprostil; Stomach Ulcer

1986
[Stomach tolerance of nonsteroidal antirheumatic drugs: comparative endoscopic study].
    Zeitschrift fur Rheumatologie, 1987, Volume: 46 Suppl 1

    Topics: Adult; Alprostadil; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Gastroscopy; Humans; Indomethacin; Misoprostol; Omeprazole; Prostaglandins E; Ranitidine; Rioprostil; Stomach Ulcer

1987
[Protective effect of omeprazole against low-dose acetylsalicylic acid. Endoscopic controlled double-blind study in healthy subjects].
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:6

    Topics: Adult; Aspirin; Double-Blind Method; Endoscopy, Gastrointestinal; Humans; Male; Omeprazole

1995
Omeprazole ameliorates aspirin-induced gastroduodenal injury.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:1

    Topics: Adult; Aspirin; Double-Blind Method; Duodenum; Female; Gastric Mucosa; Humans; Male; Omeprazole; Peptic Ulcer

1994
Transforming growth factor-alpha (TGF-alpha) levels in human proximal gastrointestinal epithelium. Effect of mucosal injury and acid inhibition.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy, Needle; Cimetidine; Duodenum; Gastric Acid; Gastric Mucosa; Humans; Intestinal Mucosa; Omeprazole; Peptic Ulcer; Pyloric Antrum; Radioimmunoassay; Transforming Growth Factor alpha

1997
[Studies on the protective effect of lansoprazole on human gastric mucosa against low-dose acetylsalicylic acid. An endoscopic controlled double-blind study].
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Duodenoscopy; Gastroscopy; Histamine H2 Antagonists; Humans; Lansoprazole; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Ranitidine

1997
[The action of the proton pump inhibitor pantoprazol against acetylsalicylic acid-induced gastroduodenopathy in comparison to ranitidine. An endoscopic controlled, double blind comparison].
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cyclooxygenase Inhibitors; Double-Blind Method; Endoscopy, Gastrointestinal; Enzyme Inhibitors; Humans; Male; Omeprazole; Pantoprazole; Peptic Ulcer; Proton Pump Inhibitors; Ranitidine; Sulfoxides

1998
Interaction of omeprazole with enteric-coated salicylate tablets.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Area Under Curve; Aspirin; Biological Availability; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Male; Omeprazole; Salicylates; Tablets, Enteric-Coated

1998
Omeprazole does not interfere with the antiplatelet effect of low-dose aspirin in man.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Aspirin; Bleeding Time; Drug Interactions; Humans; Male; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Time Factors

2000
Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen.
    The New England journal of medicine, 2001, Mar-29, Volume: 344, Issue:13

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Naproxen; Omeprazole; Organometallic Compounds; Secondary Prevention; Tetracycline

2001
Effect of Helicobacter pylori eradication on cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS) expression during gastric adaptation to aspirin (ASA) in humans.
    Microscopy research and technique, 2001, Jun-01, Volume: 53, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Clarithromycin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Electrophoresis, Polyacrylamide Gel; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Isoenzymes; Lansoprazole; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Omeprazole; Prostaglandin-Endoperoxide Synthases

2001
Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use.
    The New England journal of medicine, 2002, Jun-27, Volume: 346, Issue:26

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Peptic Ulcer; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Proton Pump Inhibitors; Recurrence; Statistics, Nonparametric

2002
Proton-pump inhibitor therapy for acetylsalicylic acid associated upper gastrointestinal symptoms: a randomized placebo-controlled trial.
    Alimentary pharmacology & therapeutics, 2003, Jul-01, Volume: 18, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Double-Blind Method; Female; Gastroesophageal Reflux; Gastrointestinal Diseases; Heartburn; Humans; Male; Middle Aged; Nausea; Omeprazole; Pain; Proton Pump Inhibitors; Rabeprazole

2003
Clopidogrel plus omeprazole compared with aspirin plus omeprazole for aspirin-induced symptomatic peptic ulcers/erosions with low to moderate bleeding/re-bleeding risk -- a single-blind, randomized controlled study.
    Alimentary pharmacology & therapeutics, 2004, Feb-01, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Peptic Ulcer Hemorrhage; Risk Factors; Single-Blind Method; Ticlopidine

2004
Effect of Helicobacter pylori eradication on anti-thrombotic dose aspirin-induced gastroduodenal mucosal injury.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:7

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Coronary Disease; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Treatment Outcome

2004
[Prospective comparative study on protective effect of the proton pump inhibitor and the prostaglandin analog on H. pylori-negative gastric mucosa of healthy subjects against low-dose aspirin].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2004, Volume: 79, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Enzyme Inhibitors; Female; Gastric Mucosa; Gastroscopy; Humans; Male; Misoprostol; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Stomach Ulcer

2004
Helicobacter pylori infection and the prevention of peptic ulcer with proton pump inhibitors in elderly subjects taking low-dose aspirin.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Dose-Response Relationship, Drug; Endoscopes, Gastrointestinal; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Pantoprazole; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Sulfoxides

2004
Ulcer recurrence in high-risk patients receiving nonsteroidalanti-inflammatory drugs plus low-dose aspirin: results of a post HOC subanalysis.
    Clinical therapeutics, 2004, Volume: 26, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Female; Humans; Lansoprazole; Male; Middle Aged; Misoprostol; Omeprazole; Peptic Ulcer Hemorrhage; Prospective Studies; Proton Pump Inhibitors; Risk Factors; Secondary Prevention; Stomach Ulcer; Treatment Outcome

2004
Helicobacter pylori eradication as the sole treatment for gastric and duodenal ulcers.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Therapy, Combination; Duodenal Ulcer; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Recurrence; Stomach Ulcer; Treatment Outcome

2005
Effect of high-dose aspirin on Helicobacter pylori eradication.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:4

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aspirin; Chronic Disease; Clarithromycin; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Pilot Projects

2005
Does adding misoprostol to standard intravenous proton pump inhibitor protocol improve the outcome of aspirin/NSAID-induced upper gastrointestinal bleeding?: a randomized prospective study.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Comorbidity; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Misoprostol; Omeprazole; Pantoprazole; Pilot Projects; Prospective Studies; Recurrence

2007
Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Regression Analysis; Stents; Ticlopidine

2010
Comparison between the effect of omeprazole and rabeprazole on the antiplatelet action of clopidogrel.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabeprazole; Ticlopidine; Treatment Outcome

2010
Clopidogrel with or without omeprazole in coronary artery disease.
    The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2010
[Impact of different proton pump inhibitors on the antiplatelet activity of clopidogrel in combination with aspirin for patients undergoing coronary stent implantation].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2010, Volume: 26, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Angioplasty, Balloon; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Omeprazole; Pantoprazole; Platelet Aggregation; Postoperative Period; Proton Pump Inhibitors; Stents; Ticlopidine

2010
Effect of omeprazole on the concentration of interleukin-6 and transforming growth factor-β1 in patients receiving dual antiplatelet therapy after percutaneous coronary intervention.
    European cytokine network, 2010, Volume: 21, Issue:4

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Biomarkers; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Gene Expression Regulation; Humans; Interleukin-6; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Predictive Value of Tests; Ticlopidine; Transforming Growth Factor beta1; Treatment Outcome

2010
Omeprazole affects clopidogrel efficacy but not ischemic events in patients with acute coronary syndrome undergoing elective percutaneous coronary intervention.
    Chinese medical journal, 2011, Volume: 124, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Ticlopidine

2011
Efficacy of Lactobacillus casei treatment on small bowel injury in chronic low-dose aspirin users: a pilot randomized controlled study.
    Journal of gastroenterology, 2011, Volume: 46, Issue:7

    Topics: Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Drug Therapy, Combination; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lacticaseibacillus casei; Male; Middle Aged; Omeprazole; Pilot Projects; Probiotics; Prospective Studies; Treatment Outcome

2011
Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:6

    Topics: Adult; Anti-Ulcer Agents; Aspirin; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Female; Humans; Least-Squares Analysis; Male; Omeprazole; Platelet Aggregation Inhibitors; Tablets, Enteric-Coated; Ticlopidine

2011
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
    World journal of gastroenterology, 2011, Dec-14, Volume: 17, Issue:46

    Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Cross-Over Studies; Double-Blind Method; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Omeprazole; Placebos; Quinolones; Young Adult

2011
Influence of omeprazole and famotidine on the antiplatelet effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes: a prospective, randomized, multicenter study.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Anti-Ulcer Agents; Aspirin; Blood Platelets; Clopidogrel; Drug Antagonism; Famotidine; Female; Humans; Male; Middle Aged; Myocardial Infarction; Omeprazole; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2012
The influence of omeprazole on platelet inhibition of clopidogrel in various CYP2C19 mutant alleles.
    Genetic testing and molecular biomarkers, 2012, Volume: 16, Issue:11

    Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Humans; Male; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Young Adult

2012
Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel.
    American heart journal, 2013, Volume: 165, Issue:2

    Topics: Administration, Oral; Adult; Aspirin; Clopidogrel; Coronary Thrombosis; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Follow-Up Studies; Gastrointestinal Diseases; Humans; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Tablets, Enteric-Coated; Ticlopidine; Treatment Outcome

2013
Pharmacokinetics and pharmacodynamics of the antiplatelet combination aspirin (acetylsalicylic acid) plus extended-release dipyridamole are not altered by coadministration with the potent CYP2C19 inhibitor omeprazole.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2013, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aspirin; Aspirin, Dipyridamole Drug Combination; Cross-Over Studies; Dipyridamole; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Young Adult

2013
Platelet inhibitory effect of clopidogrel in patients treated with omeprazole, pantoprazole, and famotidine: a prospective, randomized, crossover study.
    Clinical cardiology, 2013, Volume: 36, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Aspirin; Chi-Square Distribution; Clopidogrel; Cross-Over Studies; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Famotidine; Female; Histamine H2 Antagonists; Humans; Israel; Linear Models; Male; Middle Aged; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Single-Blind Method; Ticlopidine; Time Factors; Treatment Outcome

2013
Intragastric acidity and omeprazole exposure during dosing with either PA32540 (enteric-coated aspirin 325 mg + immediate-release omeprazole 40 mg) or enteric-coated aspirin 325 mg + enteric-coated omeprazole 40 mg - a randomised, phase 1, crossover study
    Alimentary pharmacology & therapeutics, 2013, Volume: 38, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Area Under Curve; Aspirin; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gastric Acid; Gastric Acidity Determination; Humans; Hydrogen-Ion Concentration; Male; Omeprazole; Tablets; Tablets, Enteric-Coated; Young Adult

2013
Effect of clopidogrel with or without omeprazole in patients with carotid artery stenting.
    The West Indian medical journal, 2013, Volume: 62, Issue:2

    Topics: Angiography; Aspirin; Breath Tests; Carotid Arteries; Carotid Stenosis; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Stents; Ticlopidine

2013
Effect of esomeprazole with/without acetylsalicylic acid, omeprazole and lansoprazole on pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Area Under Curve; Aspirin; Clopidogrel; Cross-Over Studies; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Healthy Volunteers; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Platelet Aggregation; Proton Pump Inhibitors; Ticlopidine; Young Adult

2014
PA32540 (a coordinated-delivery tablet of enteric-coated aspirin 325 mg and immediate-release omeprazole 40 mg) versus enteric-coated aspirin 325 mg alone in subjects at risk for aspirin-associated gastric ulcers: results of two 6-month, phase 3 studies.
    American heart journal, 2014, Volume: 168, Issue:4

    Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Incidence; Omeprazole; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stomach Ulcer; Tablets, Enteric-Coated; United States

2014
The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Dyspepsia; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Young Adult

2015
Long-Term Safety of a Coordinated Delivery Tablet of Enteric-Coated Aspirin 325 mg and Immediate-Release Omeprazole 40 mg for Secondary Cardiovascular Disease Prevention in Patients at GI Risk.
    Cardiovascular therapeutics, 2016, Volume: 34, Issue:2

    Topics: Aged; Aspirin; Cardiovascular Diseases; Dosage Forms; Drug Combinations; Female; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Treatment Outcome

2016
The Effect of Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Patients on Pharmacokinetics of (Acetyl)Salicylic Acid and Omeprazole: the ERY-PAO Study.
    Obesity surgery, 2016, Volume: 26, Issue:9

    Topics: Administration, Oral; Anti-Ulcer Agents; Area Under Curve; Aspirin; Female; Gastric Bypass; Humans; Male; Middle Aged; Obesity, Morbid; Omeprazole; Platelet Aggregation Inhibitors

2016
Aspirin Use in Secondary Cardiovascular Protection and the Development of Aspirin-Associated Erosions and Ulcers.
    Journal of cardiovascular pharmacology, 2016, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Disease Progression; Double-Blind Method; Drug Combinations; Drug Compounding; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Logistic Models; Male; Middle Aged; Odds Ratio; Omeprazole; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Secondary Prevention; Stomach Ulcer; Tablets, Enteric-Coated; Time Factors; Treatment Outcome; Young Adult

2016
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
    Journal of the American College of Cardiology, 2016, Apr-12, Volume: 67, Issue:14

    Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Obstruction; Intestinal Perforation; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Omeprazole; Pain; Peptic Ulcer; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Stroke; Ticlopidine

2016
Efficacy and Safety of Proton-Pump Inhibitors in High-Risk Cardiovascular Subsets of the COGENT Trial.
    The American journal of medicine, 2016, Volume: 129, Issue:9

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome

2016
Omeprazole vs famotidine for the prevention of gastroduodenal injury in high-risk users of low-dose aspirin: A randomized controlled trial.
    Journal of the Chinese Medical Association : JCMA, 2021, Jan-01, Volume: 84, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Famotidine; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; Male; Middle Aged; Omeprazole; Risk Factors

2021

Other Studies

101 other study(ies) available for omeprazole and aspirin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[Ulcer prevention in therapy with low-dose acetylsalicylic acid?].
    Deutsche medizinische Wochenschrift (1946), 1991, Jun-21, Volume: 116, Issue:25

    Topics: Aspirin; Brain Ischemia; Coronary Disease; Drug Therapy, Combination; Histamine H2 Antagonists; Humans; Omeprazole; Peptic Ulcer

1991
Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs.
    American journal of veterinary research, 1991, Volume: 52, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Dog Diseases; Dogs; Double-Blind Method; Gastritis; Gastroscopy; Male; Omeprazole; Random Allocation; Stomach Ulcer

1991
Different effects of cytoprotective drugs on ethanol- and aspirin-induced gastric mucosal injury in pylorus-ligated rats.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:2

    Topics: 16,16-Dimethylprostaglandin E2; 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Aspirin; Benzimidazoles; Cysteamine; Ethanol; Gastric Mucosa; Gastrointestinal Motility; Ligation; Omeprazole; Prostaglandins E, Synthetic; Pylorus; Rats

1990
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
    Japanese journal of pharmacology, 1986, Volume: 40, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcholine; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Duodenum; Gastric Mucosa; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Heart Rate; Histamine; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Omeprazole; Peptic Ulcer; Rabbits; Rats; Stress, Physiological

1986
Indomethacin-induced gastric antral ulcers in hamsters.
    Gastroenterology, 1988, Volume: 95, Issue:4

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cricetinae; Dinoprostone; Disease Models, Animal; Gastric Acid; Indomethacin; Injections, Subcutaneous; Male; Mesocricetus; Omeprazole; Peptic Ulcer Perforation; Prostaglandins E; Stomach Ulcer; Time Factors

1988
Effect of cimetidine and omeprazole on aspirin and taurocholate-induced gastric mucosal damage.
    Gut, 1986, Volume: 27, Issue:5

    Topics: Animals; Aspirin; Benzimidazoles; Cimetidine; Gastric Mucosa; Omeprazole; Rats; Taurocholic Acid

1986
Effect of cimetidine and omeprazole on aspirin- and taurocholate-induced gastric mucosal damage in the rat.
    Gut, 1985, Volume: 26, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cimetidine; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Omeprazole; Rats; Rats, Inbred Strains; Taurocholic Acid

1985
Protective action of omeprazole, a benzimidazole derivative, on gastric mucosal damage by aspirin and ethanol in rats.
    Digestion, 1983, Volume: 27, Issue:3

    Topics: Animals; Aspirin; Benzimidazoles; Dose-Response Relationship, Drug; Epoprostenol; Ethanol; Female; Gastric Fistula; Gastric Mucosa; Male; Omeprazole; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer

1983
Omeprazole provides protection against experimentally induced gastric mucosal lesions.
    European journal of pharmacology, 1983, Jul-15, Volume: 91, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Ethanol; Female; Injections, Intravenous; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Time Factors

1983
Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:5

    Topics: Animals; Aspirin; Benzimidazoles; Chemical Phenomena; Chemistry; Duodenal Ulcer; Epirizole; Gastric Juice; Indomethacin; Male; Omeprazole; Prednisolone; Rats; Rats, Inbred Strains; Stomach Ulcer

1984
Cytoprotective effect of NC-1300-O-3 against gastric lesions induced by necrotizing agents in rats.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Capillary Permeability; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Glutathione; Hexosamines; Male; Membrane Potentials; Omeprazole; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1994
Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
    Fundamental & clinical pharmacology, 1993, Volume: 7, Issue:2

    Topics: Administration, Oral; Administration, Rectal; Administration, Sublingual; Animals; Aspirin; Female; Hydrochloric Acid; Indomethacin; Ligation; Male; Models, Biological; Omeprazole; Peptic Ulcer; Rats; Rats, Wistar

1993
Effect of omeprazole on the bioavailability of unmodified and phospholipid-complexed aspirin in rats.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:5

    Topics: 1,2-Dipalmitoylphosphatidylcholine; 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Drug Carriers; Enzyme Inhibitors; Gastric Mucosa; Male; Neutralization Tests; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley

1997
Gastric mucosal function following withdrawal of omeprazole in rats.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Male; Omeprazole; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1998
Pentagastrin gastroprotection against acid is related to H2 receptor activation but not acid secretion.
    Gut, 1998, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Male; Omeprazole; Pentagastrin; Perfusion; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1998
Effects of different antisecretory drugs on gastric potential difference in the rat: comparison with sucralfate.
    Pharmacological research, 1998, Volume: 38, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Drug Interactions; Gastric Acid; Lansoprazole; Male; Nizatidine; Omeprazole; Proton Pump Inhibitors; Ranitidine; Rats; Rats, Wistar; Sucralfate

1998
Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.
    The New England journal of medicine, 1999, Oct-28, Volume: 341, Issue:18

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Enzyme Inhibitors; Gastrointestinal Diseases; Humans; Omeprazole; Proton Pump Inhibitors

1999
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
    Life sciences, 2000, Aug-18, Volume: 67, Issue:13

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Diabetes Mellitus, Experimental; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Nitric Oxide Donors; Nitro Compounds; Omeprazole; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Salicylic Acid; Stomach Diseases; Stomach Ulcer

2000
Protective effects of prostaglandins in the isolated gastric mucosa of the eel, Anguilla anguilla.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2000, Volume: 170, Issue:5-6

    Topics: Alkalies; Anguilla; Animals; Aspirin; Bicarbonates; Buffers; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; HEPES; Histamine; Indomethacin; Omeprazole; Sodium

2000
Pharmacological properties of a newly synthesized H(+)/K(+) ATPase inhibitor, 1-(2-methyl-4-methoxyphenyl)-4-.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Indomethacin; Omeprazole; Perfusion; Proton Pump Inhibitors; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach; Stomach Ulcer; Time Factors

2001
Current approaches to reducing gastrointestinal toxicity of low-dose aspirin.
    The American journal of medicine, 2001, Jan-08, Volume: 110, Issue:1A

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Misoprostol; Omeprazole; Peptic Ulcer; Ranitidine

2001
Protective effect of famotidine, omeprazole, and melatonin against acetylsalicylic acid-induced gastric damage in rats.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Aspirin; Disease Models, Animal; Drug Evaluation, Preclinical; Famotidine; Female; Free Radical Scavengers; Gastric Acidity Determination; Lipid Peroxidation; Male; Melatonin; Omeprazole; Rats; Stomach Ulcer

2001
Preventing upper gastrointestinal bleeding in patients with Helicobacter pylori infection.
    The New England journal of medicine, 2001, Jul-05, Volume: 345, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Secondary Prevention

2001
[Long-term prophylaxis with omeprazol is superior to eradication therapy in H. pylori-positive NSAIDs taking patients].
    Zeitschrift fur Gastroenterologie, 2002, Volume: 40, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Helicobacter Infections; Helicobacter pylori; Humans; Long-Term Care; Naproxen; Omeprazole; Peptic Ulcer Hemorrhage; Randomized Controlled Trials as Topic; Recurrence; Risk Factors

2002
Gastroprotective activity of solidagenone on experimentally-induced gastric lesions in rats.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Furans; Male; Naphthalenes; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer

2002
Anti-ulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Brazil; Cimetidine; Cucurbitaceae; Ethanol; Female; Flavonoids; Gastric Mucosa; Indomethacin; Male; Mice; Morphine; Motor Activity; Omeprazole; Phytotherapy; Plant Extracts; Rats; Stomach Ulcer; Tail; Toxicity Tests, Acute

2002
Gastroprotective activity of oleanolic acid derivatives on experimentally induced gastric lesions in rats and mice.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Ethanol; Hydrochloric Acid; Lansoprazole; Ligation; Male; Mice; Molecular Structure; Oleanolic Acid; Omeprazole; Phytotherapy; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Solanaceae; Stomach Ulcer; Toxicity Tests, Acute

2002
Might proton pump inhibitors prevent the antiplatelet effects of low- or very low-dose aspirin?
    Archives of internal medicine, 2002, Oct-28, Volume: 162, Issue:19

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biological Availability; Humans; Misoprostol; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Stomach Ulcer

2002
Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin.
    The New England journal of medicine, 2002, Nov-14, Volume: 347, Issue:20

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Secondary Prevention

2002
Low-dose aspirin: protection from the panacea.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Secondary Prevention; Ulcer

2002
[A case for proton pump blocker... When cough comes from the stomach].
    MMW Fortschritte der Medizin, 2002, Nov-07, Volume: 144, Issue:45

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antirheumatic Agents; Aspirin; Chronic Disease; Cough; Gastritis; Gastroesophageal Reflux; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Proton Pump Inhibitors; Risk Factors; Stomach Neoplasms; Time Factors

2002
An aspirin a day keeps the cardiologist away (but what about the gastroenterologist?).
    Gastroenterology, 2003, Volume: 124, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Drug Administration Schedule; Gastrointestinal Diseases; Heart Diseases; Humans; Lansoprazole; Omeprazole; Secondary Prevention; Ulcer

2003
Low frequency of upper gastrointestinal complications in a cohort of high-risk patients taking low-dose aspirin or NSAIDS and omeprazole.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Prospective Studies; Risk Factors; Time Factors

2003
[Heartburn without esophagitis. Symptoms more important than the finding?].
    MMW Fortschritte der Medizin, 2003, Sep-25, Volume: 145, Issue:39

    Topics: Androstadienes; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antirheumatic Agents; Aspirin; Barrett Esophagus; Child; Cross-Over Studies; Cyclooxygenase Inhibitors; Deglutition Disorders; Diagnosis, Differential; Double-Blind Method; Dyspepsia; Endoscopy; Eosinophilia; Esophagitis; Esophagitis, Peptic; Family Practice; Fluticasone; Gastroesophageal Reflux; Heartburn; Helicobacter Infections; Helicobacter pylori; Humans; Incidence; Middle Aged; Omeprazole; Prednisone; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Surveys and Questionnaires; Time Factors

2003
Re: Cost-effectiveness of aspirin chemoprevention for Barrett's esophagus.
    Journal of the National Cancer Institute, 2004, Jun-02, Volume: 96, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Anti-Ulcer Agents; Aspirin; Barrett Esophagus; Cost-Benefit Analysis; Drug Administration Schedule; Drug Costs; Drug Therapy, Combination; Esophageal Neoplasms; Evidence-Based Medicine; Humans; Male; Middle Aged; Omeprazole; Prospective Studies; Randomized Controlled Trials as Topic; Survival Rate; United Kingdom

2004
COX-2-specific inhibitor or proton pump inhibitor plus traditional NSAID: is either approach sufficient for patients at highest risk of NSAID-induced ulcers?
    Gastroenterology, 2004, Volume: 127, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Therapy, Combination; Humans; Isoenzymes; Membrane Proteins; Omeprazole; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Proton Pump Inhibitors; Pyrazoles; Sulfonamides

2004
Reducing the risks of gastrointestinal bleeding with antiplatelet therapies.
    The New England journal of medicine, 2005, Jan-20, Volume: 352, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2005
Allophylus serratus: a plant with potential anti-ulcerogenic activity.
    Journal of ethnopharmacology, 2005, Jul-14, Volume: 99, Issue:3

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Male; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Sapindaceae; Solvents; Stomach Ulcer

2005
Desmodium gangeticum: a potent anti-ulcer agent.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:6

    Topics: Alcohols; Animals; Anti-Ulcer Agents; Aspirin; Cold Temperature; Duodenal Ulcer; Ethanol; Fabaceae; Female; Guinea Pigs; Histamine; Male; Omeprazole; Peptic Ulcer; Pilot Projects; Plant Extracts; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sucralfate

2005
Disease-modifying anti-rheumatic drugs are only one of a number of potential causes of myelosuppression: a careful drug history is necessary to elucidate the cause of an adverse event.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Female; Humans; Lansoprazole; Methotrexate; Omeprazole; Pancytopenia

2006
[Gastric protection and treatment with low-dose aspirin].
    Medicina clinica, 2006, Feb-18, Volume: 126, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cohort Studies; Controlled Clinical Trials as Topic; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Meta-Analysis as Topic; Odds Ratio; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk; Risk Factors; Stomach; Stomach Ulcer; Tablets, Enteric-Coated; Time Factors

2006
Drug injury in the upper gastrointestinal tract: nonsteroidal anti-inflammatory drugs.
    Gastrointestinal endoscopy clinics of North America, 2006, Volume: 16, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Tract; Humans; Middle Aged; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sex Factors

2006
Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:11

    Topics: Aged; Angioplasty; Aryl Hydrocarbon Hydroxylases; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Drug Antagonism; Enzyme Inhibitors; Female; Humans; Male; Microfilament Proteins; Mixed Function Oxygenases; Omeprazole; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Protein Processing, Post-Translational; Thrombosis; Ticlopidine

2006
Anti-ulcer activity of crude alcoholic extract of Toona ciliata Roemer (heart wood).
    Journal of ethnopharmacology, 2007, Mar-21, Volume: 110, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Ligation; Male; Medicine, Traditional; Meliaceae; Omeprazole; Phytotherapy; Plant Bark; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological; Sucralfate

2007
[Platelet inhibition and gastric problems].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2007, Jan-04, Volume: 127, Issue:1

    Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Ticlopidine

2007
Intracranial hypotension following motor vehicle accident: an overlooked cause of post-traumatic head and neck pain?
    Pain practice : the official journal of World Institute of Pain, 2007, Volume: 7, Issue:1

    Topics: Accidents, Traffic; Analgesics; Aspirin; Blood Patch, Epidural; Diplopia; Drug Therapy, Combination; Female; Headache; Humans; Ibuprofen; Intracranial Hypotension; Middle Aged; Neck Pain; Omeprazole

2007
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship

2007
Letter to the editor, re: Nylaende M, Abdelnoor M, Stranden E, Morken B, Sandbaek G, Risum O, et al. The Oslo balloon angioplasty versus conservative treatment study (OBACT)--the 2-years results of a single centre, prospective, randomised study in patient
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2007, Volume: 33, Issue:6

    Topics: Angioplasty, Balloon; Aspirin; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Intermittent Claudication; Omeprazole; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Treatment Outcome

2007
[Endoscopic changes in the stomach and duodenal mucosa caused by minidose acetylsalicylic acid therapy and their prevention].
    Vnitrni lekarstvi, 2007, Volume: 53, Issue:10

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Duodenum; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors

2007
Use of physician education and computer alert to improve targeted use of gastroprotection among NSAID users.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiology; Coronary Care Units; Female; Gastroenterology; Humans; Inservice Training; Internship and Residency; Male; Medical Order Entry Systems; Medical Records Systems, Computerized; Middle Aged; Misoprostol; Omeprazole; Patient Discharge; Peptic Ulcer Hemorrhage; Proton Pump Inhibitors; Risk Factors; Software; Telemetry

2008
Hydroxychloroquine-induced hyperpigmentation: the staining pattern.
    Journal of cutaneous pathology, 2008, Volume: 35, Issue:12

    Topics: Aged; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Atorvastatin; Calcium Carbonate; Cardiomyopathy, Restrictive; Citalopram; Connective Tissue Diseases; Diuretics; Female; Furosemide; Glucosamine; Heptanoic Acids; Humans; Hydroxychloroquine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Lupus Erythematosus, Systemic; Magnesium; Metolazone; Middle Aged; Naproxen; Omeprazole; Potassium Chloride; Prednisone; Pyrroles; Selective Serotonin Reuptake Inhibitors; Spironolactone

2008
Clopidogrel and proton pump inhibitors: gastric protection at expense of vascular benefit?
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine

2009
Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine

2009
Aspirin in the primary prevention of vascular disease.
    Lancet (London, England), 2009, Sep-12, Volume: 374, Issue:9693

    Topics: Anti-Ulcer Agents; Aspirin; Barrett Esophagus; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Omeprazole; Patient Selection; Platelet Aggregation Inhibitors; Primary Prevention; Vascular Diseases

2009
[Does dual antiplatelet therapy always require gastroprotection? Gastroprotection with proton pump inhibitors is advisable for all patients who need dual antiplatelet therapy].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:6

    Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Therapy, Combination; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Incidence; Ketoprofen; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors

2010
Interactive medical case. Bitter pills.
    The New England journal of medicine, 2010, Oct-14, Volume: 363, Issue:16

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy; Creatinine; Fatigue; Glucocorticoids; Histamine H2 Antagonists; Humans; Kidney; Male; Methylprednisolone; Middle Aged; Nephritis, Interstitial; Omeprazole; Peptic Ulcer Hemorrhage; Stomach Ulcer; Ultrasonography; Urinalysis

2010
Clinical problem-solving. Bitter pills.
    The New England journal of medicine, 2010, Nov-04, Volume: 363, Issue:19

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Diagnosis, Differential; Fatigue; Glucocorticoids; Humans; Kidney; Male; Middle Aged; Nephritis, Interstitial; Omeprazole; Peptic Ulcer Hemorrhage; Stomach Ulcer; Urinalysis; Urination Disorders

2010
"War and Peace" with Barrett's esophagus.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:4

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Barrett Esophagus; Celecoxib; Drug Therapy, Combination; Endoscopy; Esophageal Neoplasms; Fundoplication; Gastroesophageal Reflux; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Male; Omeprazole; Pyrazoles; Quality of Life; Sulfonamides; Treatment Outcome

2011
Should prophylactic low-dose aspirin therapy be continued in peptic ulcer bleeding?
    Drugs, 2011, Jan-01, Volume: 71, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Endoscopy, Gastrointestinal; Humans; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Primary Prevention; Proton Pump Inhibitors; Risk; Risk Factors

2011
Double-dose clopidogrel in patients undergoing PCI for ACS.
    Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2011
Anti-ulcer constituents of Annona squamosa twigs.
    Fitoterapia, 2011, Volume: 82, Issue:4

    Topics: Animals; Annona; Anti-Ulcer Agents; Aporphines; Aspirin; Benzylisoquinolines; Berberine Alkaloids; Cold Temperature; Dinoprostone; Disaccharides; Drug Evaluation, Preclinical; Duodenal Ulcer; Ethanol; Gastric Juice; Gastrins; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Histamine; Ligation; Omeprazole; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Physiological

2011
Relationship between cardiovascular outcomes and proton pump inhibitor use in patients receiving dual antiplatelet therapy after acute coronary syndrome.
    Pharmacoepidemiology and drug safety, 2011, Volume: 20, Issue:10

    Topics: Acute Coronary Syndrome; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Databases, Factual; Drug Interactions; Esomeprazole; Female; Herb-Drug Interactions; Hospitalization; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Retrospective Studies; Ticlopidine; Treatment Outcome

2011
Gastroprotective activities of Turnera diffusa Willd. ex Schult. revisited: Role of arbutin.
    Journal of ethnopharmacology, 2012, May-07, Volume: 141, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Arbutin; Aspirin; Cell Line; Cytoprotection; Disease Models, Animal; Ethanol; Female; Gastric Acid; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Immunologic Factors; Interleukin-10; Interleukin-6; Lipid Peroxidation; Liver; Male; Mucus; Nitric Oxide; Omeprazole; Phytotherapy; Plant Extracts; Plants, Medicinal; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Turnera

2012
A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Interactions; Famotidine; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Omeprazole; Peroxidase; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine

2012
Effects of PPIs and an H2 blocker on the antiplatelet function of clopidogrel in Japanese patients under dual antiplatelet therapy.
    Journal of atherosclerosis and thrombosis, 2012, Volume: 19, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Asian People; Aspirin; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Histamine H2 Antagonists; Humans; Male; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Ticlopidine

2012
Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Drug Therapy, Combination; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Hypertension; Male; Naproxen; Nitrates; Obesity; Omeprazole; Pyrazoles; Rats; Rats, Inbred SHR; Rats, Wistar; Rats, Zucker; Sulfonamides

2012
I've taken aspirin for years to prevent heart attack, and now I've developed an ulcer. My doctor told me to keep taking aspirin along with Prilosec. Why keep taking aspirin if it caused my ulcer?
    Mayo Clinic health letter (English ed.), 2012, Volume: 30, Issue:3

    Topics: Anti-Ulcer Agents; Aspirin; Humans; Myocardial Infarction; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors

2012
Antiulcerogenic activity of hydroalcoholic fruit extract of Pithecellobium dulce in different experimental ulcer models in rats.
    Journal of ethnopharmacology, 2012, Jul-13, Volume: 142, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Carbohydrate Metabolism; Cell Proliferation; Cold Temperature; Dinoprostone; Disease Models, Animal; Ethanol; Fabaceae; Fruit; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; Male; Mucins; Omeprazole; Peroxidase; Phytotherapy; Plant Extracts; Proteins; Rats; Rats, Wistar; Severity of Illness Index; Stomach Ulcer

2012
Evaluation of antiulcer activity of indole-3-carbinol and/or omeprazole on aspirin-induced gastric ulcer in rats.
    Toxicology and industrial health, 2014, Volume: 30, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cyclooxygenase 2; Indoles; Male; Omeprazole; Rats; Stomach; Stomach Ulcer

2014
Is 325 mg of prevention worth a pound of cure?
    Gastroenterology, 2012, Volume: 143, Issue:4

    Topics: Aspirin; Barrett Esophagus; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Male; Omeprazole; Proton Pump Inhibitors

2012
Proton-pump inhibitors could be innocent when used concomitantly with clopidogrel.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:11

    Topics: Acute Coronary Syndrome; Anti-Ulcer Agents; Aspirin; Blood Platelets; Clopidogrel; Famotidine; Female; Humans; Male; Omeprazole; Platelet Aggregation Inhibitors; Ticlopidine

2012
Anti-secretory and cyto-protective effects of chebulinic acid isolated from the fruits of Terminalia chebula on gastric ulcers.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Apr-15, Volume: 20, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Fruit; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; Hydrolyzable Tannins; Inhibitory Concentration 50; Ligation; Male; Mucins; Omeprazole; Phytotherapy; Plant Extracts; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Stomach; Stomach Ulcer; Sucralfate; Terminalia

2013
Common medications among dental outpatients: considerations in general dental practice.
    The New Zealand dental journal, 2012, Volume: 108, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Cilazapril; Dental Clinics; Drug Interactions; Drug Utilization; Female; General Practice, Dental; Humans; Male; Middle Aged; New Zealand; Omeprazole; Outpatients; Polypharmacy; Retrospective Studies; Young Adult

2012
Anti-secretory and cyto-protective effects of peganine hydrochloride isolated from the seeds of Peganum harmala on gastric ulcers.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Oct-15, Volume: 20, Issue:13

    Topics: Alcohols; Alkaloids; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Cold Temperature; Disease Models, Animal; H(+)-K(+)-Exchanging ATPase; Male; Molecular Structure; Omeprazole; Peganum; Plant Extracts; Pylorus; Quinazolines; Rats; Rats, Sprague-Dawley; Seeds; Stomach Ulcer; Sucralfate

2013
[HP eradication prevents recurrent hemorrhages caused by acetylsalicylic acid].
    MMW Fortschritte der Medizin, 2013, Jun-27, Volume: 155, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cohort Studies; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Long-Term Care; Omeprazole; Peptic Ulcer Hemorrhage; Prospective Studies; Proton Pump Inhibitors; Secondary Prevention

2013
Comparison of proton pump inhibitor and histamine-2 receptor antagonist in the prevention of recurrent peptic ulcers/erosions in long-term low-dose aspirin users: a retrospective cohort study.
    BioMed research international, 2014, Volume: 2014

    Topics: Aged; Aged, 80 and over; Aspirin; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Retrospective Studies; Thromboembolism

2014
Histopathological evaluation of gastro protective effect of Berberis vulgaris (Zereshk) seeds against aspirin induced ulcer in albino mice.
    Pakistan journal of pharmaceutical sciences, 2015, Volume: 28, Issue:6

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Berberis; Cell Proliferation; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Mice; Omeprazole; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Powders; Proton Pump Inhibitors; Seeds; Stomach Ulcer

2015
A COGENT Argument for Gastrointestinal Protection With Low-Dose Aspirin.
    Journal of the American College of Cardiology, 2016, Apr-12, Volume: 67, Issue:14

    Topics: Aspirin; Female; Humans; Male; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2016
The budget impact of using enteric-coated aspirin 325 mg + immediate-release omeprazole 40 mg to prevent recurrent cardiovascular events.
    Journal of medical economics, 2017, Volume: 20, Issue:6

    Topics: Adult; Aged; Aspirin; Budgets; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Markov Chains; Medication Adherence; Middle Aged; Models, Econometric; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine

2017
Combination cardiovascular drugs.
    Nursing, 2017, Volume: 47, Issue:8

    Topics: Aminobutyrates; Amlodipine; Aspirin; Biphenyl Compounds; Cardiovascular Agents; Cardiovascular Diseases; Drug Combinations; Humans; Nebivolol; Omeprazole; Perindopril; Tetrazoles; Valsartan

2017
Stability Indicating Liquid Chromatographic Method for Simultaneous Determination of Aspirin and Omeprazole.
    Current drug discovery technologies, 2018, Volume: 15, Issue:4

    Topics: Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinations; Drug Compounding; Drug Stability; Feasibility Studies; Fibrinolytic Agents; Humans; Omeprazole; Quality Control; Stomach Ulcer; Thrombosis

2018
Small bowel obstruction secondary to enteroenteric fistula: An uncommon complication in chronic NSAID users.
    Cirugia espanola, 2020, Volume: 98, Issue:4

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Female; Humans; Ileal Diseases; Intestinal Fistula; Intestinal Obstruction; Intestinal Perforation; Intestine, Small; Jejunal Diseases; Omeprazole; Tomography, X-Ray Computed

2020
Green analysis of newly approved binary omeprazole/aspirin mixture in presence of aspirin impurity using ultra-high-performance liquid chromatography and thin-layer chromatography methods.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:2

    Topics: Aspirin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Contamination; Green Chemistry Technology; Limit of Detection; Linear Models; Omeprazole; Reproducibility of Results; Salicylic Acid

2021
Treatment effects of Shilajit on aspirin-induced gastric lesions in rats.
    Physiological reports, 2021, Volume: 9, Issue:7

    Topics: Animals; Antioxidants; Aspirin; Gastric Mucosa; Male; Minerals; Omeprazole; Oxidative Stress; Peptic Ulcer; Rats; Rats, Wistar; Resins, Plant

2021
Application of different spectrofluorimetric approaches for quantitative determination of acetylsalicylic acid and omeprazole in recently approved pharmaceutical preparation and human plasma.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021, Dec-05, Volume: 262

    Topics: Aspirin; Calibration; Humans; Omeprazole; Spectrometry, Fluorescence; Tablets

2021
Spectrophotometric Determination of Aspirin and Omeprazole in the Presence of Salicylic Acid as a Degradation Product: A Comparative Evaluation of Different Univariate/Multivariate Post Processing Algorithms.
    Journal of AOAC International, 2022, Feb-04, Volume: 105, Issue:1

    Topics: Algorithms; Aspirin; Calibration; Humans; Least-Squares Analysis; Omeprazole; Salicylic Acid; Spectrophotometry

2022
Earth friendly spectrophotometric methods based on different manipulation approaches for simultaneous determination of aspirin and omeprazole in binary mixture and pharmaceutical dosage form: Comparative statistical study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, Feb-05, Volume: 266

    Topics: Aspirin; Humans; Omeprazole; Pharmaceutical Preparations; Spectrophotometry

2022
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of Symptom Onset with Prescribed and Non-Prescribed Treatments Between November 2
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Dec-30, Volume: 27

    Topics: Aged; Aged, 80 and over; Aspirin; Betamethasone; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Dietary Supplements; Early Diagnosis; Female; Flavonoids; Follow-Up Studies; Heparin, Low-Molecular-Weight; Hospitalization; Humans; Indomethacin; Italy; Male; Middle Aged; Omeprazole; Patient Acuity; Retrospective Studies; Risk Assessment; SARS-CoV-2; Time; Time-to-Treatment; Treatment Outcome

2021
Gastric cancer risk in the elderly is associated with omeprazole use and inversely associated with aspirin use.
    European journal of gastroenterology & hepatology, 2023, 09-01, Volume: 35, Issue:9

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Omeprazole; Risk; Stomach Neoplasms

2023