omeprazole and ascorbic acid

omeprazole has been researched along with ascorbic acid in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (18.52)18.2507
2000's12 (44.44)29.6817
2010's8 (29.63)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Asaki, S; Ohara, T; Sasaki, R; Shibuya, D; Toyota, T1
Reed, PI1
Ciofani, G; Cuccurullo, F; de Gioia, S; Festi, D; Lapenna, D1
Blot, WJ; Brown, LM; Chang, YS; Fraumeni, JF; Gail, MH; Groves, FD; Heinrich, JP; Hu, J; Jin, ML; Li, JY; Liu, WD; Ma, JL; Mark, SD; Rabkin, CS; Xu, GW; You, WC; Zhang, L1
Carswell, A; McColl, KE; Mowat, C; Wirz, A1
Carswell, A; Gillen, D; Gilmour, D; Hossack, M; McColl, KE; Mowat, C; Preston, T; Williams, C; Wirz, A1
Brown, LM; Chang, YS; Fraumeni, JF; Gail, MH; Heinrich, J; Liu, WD; Ma, JL; Xu, GW; Yang, CS; You, WC; Zhang, L1
Bavbek, N; Koçkar, C; Oztürk, M1
Fukuda, Y; Harada, N; Nawata, H; Ohtani, A; Yoshinaga, M1
Chuang, CH; Huang, AH; Sheu, BS; Wu, JJ; Yang, HB1
Koch, TR; Opara, EC; Petro, A; Yuan, LX1
Carswell, A; Fyffe, V; Henry, EB; McColl, KE; Wirz, A1
Blot, WJ; Brown, LM; Chang, YS; Crystal-Mansour, S; Fraumeni, JF; Gail, MH; Hu, Y; Jin, ML; Li, JY; Liu, WD; Ma, JL; Pan, KF; Pee, D; Xu, GW; You, WC; Zhang, L1
Abe, Y; Ara, N; Asanuma, K; Iijima, K; Imatani, A; Ishiyama, F; Koike, T; Ohara, S; Shimosegawa, T; Yoshitake, J1
McColl, KE1
Derakhshan, F; Haghazali, M; Mirsattari, D; Mohsenian, N; Molaei, M; Talaie, R; Zali, MR; Zojaji, H1
Davis, ME; Gaikwad, NW; Lisowyj, MP; Mirvish, SS1
Eberlein, B; Gebhardt, E; Gilbertz, KP; Placzek, M; Przybilla, B1
Blot, WJ; Brown, LM; Crystal-Mansour, S; Fraumeni, JF; Gail, MH; Han, ZX; Hu, Y; Li, JY; Liu, WD; Ma, JL; Pan, KF; Pee, D; Shen, L; You, WC; Zhang, L1
Ali, ES; Alves, LBDS; Braga, AL; da Mata, AMOF; Das, AK; de Lima, RMT; de Meneses, APM; Dev, S; Dos Reis, AC; E Sousa, JMC; Islam, MT; Khan, IN; Melo-Cavalcante, AAC; Mishra, SK; Mubarak, MS; Paz, MFCJ; Rouf, R; Santos, JVO; Shaw, S; Shil, MC; Shilpi, JA; Uddin, SJ1
Braga, AL; Cronemberger, LAC; da Silva, MBS; de Aguiar, RPS; de Alencar, MVOB; de Carvalho, RM; de Lima, RMT; de Meneses, APM; Duarte, JL; Islam, MT; Marcelo de Castro E Sousa, J; Melo-Cavalcante, AAC; Mubarak, MS; Paz, MFCJ1
Abed, MN; Alassaf, FA; Alfahad, M; Jasim, MHM; Qazzaz, ME1
Braga, AL; de Alencar, MVOB; de Lima, RMT; de Meneses, APM; do Nascimento, PB; Islam, MT; Júnior, ALG; Melo-Cavalcante, AAC; Paz, MFCJ; Santos, JVO; Sousa, JMCE1

Reviews

2 review(s) available for omeprazole and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effect of proton pump inhibitors on vitamins and iron.
    The American journal of gastroenterology, 2009, Volume: 104 Suppl 2

    Topics: Absorption; Ascorbic Acid; Biological Availability; Gastric Juice; Helicobacter Infections; Helicobacter pylori; Humans; Iron; Omeprazole; Proton Pump Inhibitors; Vitamin B 12; Vitamins

2009

Trials

9 trial(s) available for omeprazole and ascorbic acid

ArticleYear
The ECP-IM intervention study.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1994, Volume: 3 Suppl 2

    Topics: Ascorbic Acid; Clarithromycin; Double-Blind Method; Drug Combinations; Europe; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Omeprazole; Placebos; Stomach Neoplasms

1994
Factorial trial of three interventions to reduce the progression of precancerous gastric lesions in Shandong, China: design issues and initial data.
    Controlled clinical trials, 1998, Volume: 19, Issue:4

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Ascorbic Acid; China; Double-Blind Method; Drug Therapy, Combination; Garlic; Helicobacter Infections; Helicobacter pylori; Humans; Middle Aged; Omeprazole; Penicillins; Phytotherapy; Plant Extracts; Plants, Medicinal; Precancerous Conditions; Selenium; Stomach Neoplasms; Vitamin E

1998
An intervention trial to inhibit the progression of precancerous gastric lesions: compliance, serum micronutrients and S-allyl cysteine levels, and toxicity.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2001, Volume: 10, Issue:3

    Topics: Adult; Aged; Amoxicillin; Antioxidants; Ascorbic Acid; beta Carotene; China; Double-Blind Method; Drug Therapy, Combination; Female; Garlic; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Patient Compliance; Penicillins; Phytotherapy; Plants, Medicinal; Precancerous Conditions; Prevalence; Selenium; Stomach Neoplasms; Treatment Outcome; Vitamin E

2001
Helicobacter pylori eradication with beta carotene, ascorbic acid and allicin.
    Acta medica (Hradec Kralove), 2001, Volume: 44, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Ascorbic Acid; beta Carotene; Clarithromycin; Disulfides; Drug Therapy, Combination; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Omeprazole; Sulfinic Acids

2001
Vitamin C and E supplements to lansoprazole-amoxicillin-metronidazole triple therapy may reduce the eradication rate of metronidazole-susceptible Helicobacter pylori infection.
    Helicobacter, 2002, Volume: 7, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Ascorbic Acid; Dietary Supplements; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation; Lansoprazole; Male; Metronidazole; Omeprazole; Severity of Illness Index; Stomach Diseases; Treatment Outcome; Vitamin E

2002
Proton pump inhibitors reduce the bioavailability of dietary vitamin C.
    Alimentary pharmacology & therapeutics, 2005, Sep-15, Volume: 22, Issue:6

    Topics: Ascorbic Acid; Biological Availability; Enzyme Inhibitors; Female; Gastric Acid; Helicobacter Infections; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Male; Omeprazole; Proton Pump Inhibitors

2005
Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions.
    Journal of the National Cancer Institute, 2006, Jul-19, Volume: 98, Issue:14

    Topics: Adult; Amoxicillin; Ascorbic Acid; China; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Factor Analysis, Statistical; Female; Garlic; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Logistic Models; Male; Middle Aged; Omeprazole; Phytotherapy; Precancerous Conditions; Prevalence; Selenium; Severity of Illness Index; Stomach Neoplasms; Vitamin E

2006
The efficacy of Helicobacter pylori eradication regimen with and without vitamin C supplementation.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2009, Volume: 41, Issue:9

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Ascorbic Acid; Bismuth; Dietary Supplements; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Metronidazole; Middle Aged; Omeprazole; Young Adult

2009
Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality.
    Journal of the National Cancer Institute, 2012, Mar-21, Volume: 104, Issue:6

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Ascorbic Acid; China; Confounding Factors, Epidemiologic; Dietary Supplements; Factor Analysis, Statistical; Female; Follow-Up Studies; Garlic; Gastrointestinal Agents; Helicobacter Infections; Helicobacter pylori; Humans; Incidence; Logistic Models; Male; Middle Aged; Odds Ratio; Omeprazole; Precancerous Conditions; Proportional Hazards Models; Stomach Neoplasms; Vitamin E; Vitamins

2012

Other Studies

16 other study(ies) available for omeprazole and ascorbic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Effect of omeprazole on ascorbate free radical formation.
    The Tohoku journal of experimental medicine, 1992, Volume: 167, Issue:3

    Topics: Animals; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Guinea Pigs; Male; Omeprazole; Oxidation-Reduction

1992
Antioxidant properties of omeprazole.
    FEBS letters, 1996, Mar-11, Volume: 382, Issue:1-2

    Topics: Anti-Ulcer Agents; Antioxidants; Ascorbic Acid; beta Carotene; Carotenoids; Chlorides; Copper; Deoxyribose; Ferric Compounds; Hydrogen-Ion Concentration; Hypochlorous Acid; Omeprazole; Oxidation-Reduction

1996
Omeprazole and dietary nitrate independently affect levels of vitamin C and nitrite in gastric juice.
    Gastroenterology, 1999, Volume: 116, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Ascorbic Acid; Female; Gastric Acidity Determination; Gastric Juice; Helicobacter pylori; Humans; Male; Middle Aged; Nitrates; Nitrites; Omeprazole

1999
Omeprazole, Helicobacter pylori status, and alterations in the intragastric milieu facilitating bacterial N-nitrosation.
    Gastroenterology, 2000, Volume: 119, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Ascorbic Acid; Female; Gastric Juice; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Male; Microbiological Techniques; Middle Aged; Nitrites; Nitrosation; Omeprazole; Saliva

2000
Vitamin C inhibits corpus gastritis in Helicobacter pylori-infected patients during acid-suppressive therapy.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:11

    Topics: Acids; Anti-Ulcer Agents; Ascorbic Acid; Drug Therapy, Combination; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole

2001
Effects of omeprazole and ascorbate on gastric emptying and antioxidant levels in a mouse model of glutathione depletion.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:11

    Topics: Animals; Antioxidants; Ascorbic Acid; Gastric Emptying; Gastric Mucosa; Glutathione; Lipid Peroxides; Mice; Mice, Inbred Strains; Models, Animal; Omeprazole

2002
Exogenous luminal nitric oxide exacerbates esophagus tissue damage in a reflux esophagitis model of rats.
    Scandinavian journal of gastroenterology, 2009, Volume: 44, Issue:5

    Topics: Analysis of Variance; Animals; Ascorbic Acid; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Esophagitis, Peptic; Esophagogastric Junction; Immunohistochemistry; Male; Nitric Oxide; Omeprazole; Peroxidase; Probability; Random Allocation; Rats; Rats, Wistar; Sensitivity and Specificity

2009
Effect of feeding nitrite, ascorbate, hemin, and omeprazole on excretion of fecal total apparent N-nitroso compounds in mice.
    Chemical research in toxicology, 2008, Volume: 21, Issue:12

    Topics: Animal Feed; Animals; Ascorbic Acid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Feces; Hemin; Male; Meat Products; Mice; Nitroso Compounds; Omeprazole; Sodium Nitrite

2008
In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins.
    Acta dermato-venereologica, 2012, Volume: 92, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ascorbic Acid; Cimetidine; Erythrocytes; Famotidine; Hemolysis; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lansoprazole; Lovastatin; Nizatidine; Omeprazole; Pantoprazole; Pravastatin; Proton Pump Inhibitors; Ranitidine; Ultraviolet Rays

2012
Toxicogenetic study of omeprazole and the modulatory effects of retinol palmitate and ascorbic acid on Allium cepa.
    Chemosphere, 2018, Volume: 204

    Topics: Allium; Antioxidants; Ascorbic Acid; Diterpenes; DNA Damage; Mutagenesis; Mutagens; Omeprazole; Plant Extracts; Retinyl Esters; Toxicogenetics; Vitamin A

2018
Ascorbic acid and retinol palmitate modulatory effect on omeprazole-induced oxidative damage, and the cytogenetic changes in S. cerevisiae and S180 cells.
    Chemico-biological interactions, 2019, Sep-25, Volume: 311

    Topics: Animals; Ascorbic Acid; Cell Line, Tumor; Cell Survival; Chromosome Aberrations; Cyclophosphamide; Diterpenes; Hydrogen Peroxide; Mice; Micronucleus Tests; Omeprazole; Oxidative Stress; Retinyl Esters; Saccharomyces cerevisiae; Vitamin A

2019
Comparison of Antioxidant Effects of the Proton Pump-Inhibiting Drugs Omeprazole, Esomeprazole, Lansoprazole, Pantoprazole, and Rabeprazole.
    Pharmacology, 2020, Volume: 105, Issue:11-12

    Topics: Antioxidants; Ascorbic Acid; Biphenyl Compounds; Esomeprazole; Free Radicals; In Vitro Techniques; Inhibitory Concentration 50; Lansoprazole; Omeprazole; Pantoprazole; Picrates; Proton Pump Inhibitors; Rabeprazole; Spectrophotometry

2020
Antioxidative defense against omeprazole-induced toxicogenetical effects in Swiss mice.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Comet Assay; Cyclophosphamide; Diterpenes; DNA Repair; Dose-Response Relationship, Drug; Male; Mice; Mutagenesis; Omeprazole; Proton Pump Inhibitors; Retinyl Esters

2021