omeprazole and 1,7-dimethylxanthine

omeprazole has been researched along with 1,7-dimethylxanthine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roots, I; Rost, KL1
Bohnemeier, H; Brockmöller, J; Fuhr, U; Roots, I; Rost, KL; Thomsen, T; Zaigler, M1
Kim, DH; Oh, KS; Park, SJ; Shin, JG; Shinde, DD1
Akamatsu, T; Chida, K; Inui, N; Karayama, M; Namiki, N; Tanaka, S; Uchida, S; Watanabe, H1
Aharchi, F; De Smedt, G; Hoetelmans, RM; Kakuda, TN; Leopold, L; Onkelinx, J; Peeters, M; Stevens, T; Van Solingen-Ristea, RM1

Trials

2 trial(s) available for omeprazole and 1,7-dimethylxanthine

ArticleYear
Omeprazole weakly inhibits CYP1A2 activity in man.
    International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:11

    Topics: Adult; Binding, Competitive; Biomarkers; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Omeprazole; Single-Blind Method; Theophylline

1999
The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Cross-Over Studies; Cytochrome P-450 Enzyme System; Dextromethorphan; Digoxin; Female; Healthy Volunteers; Humans; Male; Midazolam; Middle Aged; Nitriles; Omeprazole; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Theophylline; Warfarin; Young Adult

2014

Other Studies

3 other study(ies) available for omeprazole and 1,7-dimethylxanthine

ArticleYear
Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios: coincidence with plasma clearance and breath test.
    Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breath Tests; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Male; Mephenytoin; Middle Aged; Omeprazole; Oxidoreductases, N-Demethylating; Phenotype; Theophylline; Uric Acid

1994
High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, May-01, Volume: 895-896

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Caffeine; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Drug Stability; Humans; Imidazoles; Linear Models; Liquid-Liquid Extraction; Losartan; Omeprazole; Pharmaceutical Preparations; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles; Theophylline

2012
Chronological effects of rifampicin discontinuation on cytochrome P450 activity in healthy Japanese volunteers, using the cocktail method.
    Clinical pharmacology and therapeutics, 2013, Volume: 94, Issue:6

    Topics: Adult; Antibiotics, Antitubercular; Asian People; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Imidazoles; Losartan; Male; Midazolam; Omeprazole; Rifampin; Tetrazoles; Theophylline; Time Factors; Withholding Treatment

2013