omega-n-methylarginine has been researched along with zaprinast in 11 studies
| Studies (omega-n-methylarginine) | Trials (omega-n-methylarginine) | Recent Studies (post-2010) (omega-n-methylarginine) | Studies (zaprinast) | Trials (zaprinast) | Recent Studies (post-2010) (zaprinast) |
|---|---|---|---|---|---|
| 4,411 | 344 | 336 | 576 | 2 | 87 |
| Protein | Taxonomy | omega-n-methylarginine (IC50) | zaprinast (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 1.9442 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Canis lupus familiaris (dog) | 0.76 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | 2.6 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | 3.55 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | 2.6 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | 3.55 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | 3.55 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Bos taurus (cattle) | 0.4 | |
| G-protein coupled receptor 35 | Homo sapiens (human) | 0.8294 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF; Rohde, JA | 1 |
| Chang, R; Fineman, JR; Soifer, SJ | 1 |
| Holmes, L; Jenkins, DC; Moncada, S; Radomski, MW | 1 |
| Bayguinov, O; Sanders, KM | 1 |
| Boels, PJ; Deutsch, J; Haworth, SG; Hislop, AA; Tulloh, RM | 1 |
| Haworth, SG; Hislop, AA; Tulloh, RM | 1 |
| Johns, RA; Li, D; Shirakami, G; Zhan, X | 1 |
| Ghofrani, HA; Grimminger, F; Hardebusch, T; Schermuly, RT; Seeger, W; Tadic, A; Voswinckel, R; Weissmann, N | 1 |
| Donahue, JK; Lawrence, JH; Marbán, E; Nagata, K | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Russo, I; Trovati, M | 1 |
| Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
11 other study(ies) available for omega-n-methylarginine and zaprinast
| Article | Year |
|---|---|
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxidopamine; Phosphodiesterase Inhibitors; Purinones; Pyrogallol; Sympathectomy, Chemical | 1992 |
L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blood Pressure; Cardiac Output; Heart Rate; Hypertension, Pulmonary; Isomerism; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Purinones; Sheep; Vasodilation | 1991 |
Human colorectal adenocarcinoma cells: differential nitric oxide synthesis determines their ability to aggregate platelets.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Arginine; Colorectal Neoplasms; Epoprostenol; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Purinones; Tumor Cells, Cultured; Vasodilator Agents | 1991 |
Role of nitric oxide as an inhibitory neurotransmitter in the canine pyloric sphincter.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic GMP; Dogs; Duodenum; Electric Stimulation; Female; Gastric Mucosa; In Vitro Techniques; Intercellular Junctions; Intestinal Mucosa; Male; Membrane Potentials; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Phentolamine; Propranolol; Purinones; Pylorus; Stomach; Tetrodotoxin | 1993 |
Chronic hypoxia inhibits postnatal maturation of porcine intrapulmonary artery relaxation.
Topics: Acetylcholine; Animals; Animals, Newborn; Atmospheric Pressure; Calcimycin; Chronic Disease; Cyclic GMP; Dinoprost; Endothelium, Vascular; Heart; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Potassium Chloride; Pulmonary Artery; Purinones; Swine; Vasodilation; Vasomotor System | 1997 |
Role of NO in recovery from neonatal hypoxic pulmonary hypertension.
Topics: Acetylcholine; Animals; Animals, Newborn; Calcimycin; Cyclic GMP; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Hypoxia; Nitric Oxide; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Pulmonary Artery; Purinones; Swine; Tunica Intima; Vasoconstriction; Vasodilator Agents | 1999 |
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cells, Cultured; Cilia; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Glutathione; Indoles; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Oxadiazoles; Purinones; Quinoxalines; Rats; S-Nitrosoglutathione; Signal Transduction; Trachea | 2000 |
Nitric oxide (NO)-dependent but not NO-independent guanylate cyclase activation attenuates hypoxic vasoconstriction in rabbit lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aminoquinolines; Animals; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Guanylate Cyclase; Hypoxia; In Vitro Techniques; Lung; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pulmonary Artery; Purinones; Rabbits; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Phosphodiesterase inhibitor-mediated potentiation of adenovirus delivery to myocardium.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenoviruses, Human; Animals; beta-Galactosidase; Cyclic GMP; Drug Synergism; Endothelial Growth Factors; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Guanylate Cyclase; Heart; Humans; Isoquinolines; Lymphokines; Myocardium; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Piperazines; Purines; Purinones; Pyridines; Rabbits; Sildenafil Citrate; Sulfones; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcysteine; Adenosine Diphosphate; Adult; Calcimycin; Cell Membrane Permeability; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Humans; Ionomycin; Male; omega-N-Methylarginine; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Quinoxalines | 2001 |
Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analgesics; Animals; Cyclic GMP; Formaldehyde; Glyburide; Injections, Spinal; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Potassium Channels; Purinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |