Page last updated: 2024-09-03

omega-n-methylarginine and yohimbine

omega-n-methylarginine has been researched along with yohimbine in 10 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(yohimbine)
Trials
(yohimbine)
Recent Studies (post-2010) (yohimbine)
4,4113443365,893253532

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)yohimbine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0353
Cytochrome P450 2D6Homo sapiens (human)1.02
D(2) dopamine receptorHomo sapiens (human)2.06
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-2B adrenergic receptorHomo sapiens (human)0.0428
Alpha-2C adrenergic receptorHomo sapiens (human)0.0466
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.126
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-1D adrenergic receptorHomo sapiens (human)1.013
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.126
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.074
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 6Homo sapiens (human)1.689

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's6 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
Maragoudakis, ME; Pipili-Synetos, E; Sideri, E1
Devissaguet, M; Ferreira, SH; Lesieur, D; Lorenzetti, BB; Tsouderos, Y1
Kaneko, K; Sunano, S1
Anfossi, G; Cavalot, F; Hahn, AW; Massucco, P; Mattiello, L; Mularoni, EM; Trovati, M1
Bruck, H; Gössl, M; Kohnle, M; Philipp, T; Schäfers, RF; Spitthöver, R; Wenzel, RR1
Bruck, H; Philipp, T; Schäfers, RF; Siffert, W; Wenzel, RR1
Ardilouze, JL; Currie, JM; Fielding, BA; Frayn, KN; Karpe, F1
Honda, M; Ono, H; Takasu, K; Tanabe, M1
Andrews, CN; Bharucha, AE; Camilleri, M; Charkoudian, N; Low, PA; Sletten, D; Zinsmeister, AR1

Trials

1 trial(s) available for omega-n-methylarginine and yohimbine

ArticleYear
Effects of glucagon-like peptide-1, yohimbine, and nitrergic modulation on sympathetic and parasympathetic activity in humans.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:3

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Blood Glucose; Blood Pressure; Catecholamines; Enzyme Inhibitors; Female; Glucagon-Like Peptide 1; Heart Rate; Humans; Incretins; Male; Middle Aged; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Parasympathetic Nervous System; Sympathetic Nervous System; Vasoconstriction; Yohimbine

2008

Other Studies

9 other study(ies) available for omega-n-methylarginine and yohimbine

ArticleYear
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
Role of endothelium on alpha-adrenoceptor responsiveness and prostacyclin release from the mesenteric arterial bed of the rat.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:3

    Topics: Animals; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; omega-N-Methylarginine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1991
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
    British journal of pharmacology, 1995, Volume: 114, Issue:2

    Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine

1995
Involvement of alpha-adrenoceptors in the endothelium-dependent depression of noradrenaline-induced contraction in rat aorta.
    European journal of pharmacology, 1993, Aug-24, Volume: 240, Issue:2-3

    Topics: Animals; Aorta, Thoracic; Arginine; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine

1993
Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: dependence on cyclic guanosine monophosphate and modulation of catecholamine effects.
    Diabetologia, 1996, Volume: 39, Issue:10

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analysis of Variance; Arterioles; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; Insulin; Isoproterenol; Kinetics; Methylene Blue; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Propranolol; Receptors, Adrenergic, beta; Recombinant Proteins; Yohimbine

1996
The nitric oxide synthase inhibitor L-NMMA potentiates noradrenaline-induced vasoconstriction: effects of the alpha2-receptor antagonist yohimbine.
    Journal of hypertension, 2001, Volume: 19, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Blood Vessels; Drug Synergism; Enzyme Inhibitors; Forearm; Humans; Male; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Skin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine

2001
Enhanced vasoconstriction to endothelin-1, angiotensin II and noradrenaline in carriers of the GNB3 825T allele in the skin microcirculation.
    Pharmacogenetics, 2002, Volume: 12, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Alleles; Angiotensin II; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heterotrimeric GTP-Binding Proteins; Heterozygote; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Nitric Oxide Synthase; Norepinephrine; Oligopeptides; omega-N-Methylarginine; Peptides, Cyclic; Piperidines; Protein Subunits; Skin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine

2002
Nitric oxide and beta-adrenergic stimulation are major regulators of preprandial and postprandial subcutaneous adipose tissue blood flow in humans.
    Circulation, 2004, Jan-06, Volume: 109, Issue:1

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Eating; Female; Glucose; Humans; Infusions, Parenteral; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phentolamine; Propranolol; Receptors, Adrenergic, beta; Regional Blood Flow; Xenon Radioisotopes; Yohimbine

2004
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
    British journal of pharmacology, 2006, Volume: 148, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine

2006