Page last updated: 2024-09-03

omega-n-methylarginine and wortmannin

omega-n-methylarginine has been researched along with wortmannin in 12 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(wortmannin)
Trials
(wortmannin)
Recent Studies (post-2010) (wortmannin)
4,4113443364,0662726

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's9 (75.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Etgen, GJ; Fryburg, DA; Gibbs, EM1
Bolander, FF1
Austin, C; Shaw, L; Taggart, MJ1
Avraham, H; Avraham, S; Radisavljevic, Z1
Fulton, D; Gratton, JP; Groszmann, RJ; Iwakiri, Y; McCabe, TJ; Sessa, WC; Tsai, MH1
Chun, YJ; Kim, MY; Lee, S; Park, S; Yang, SA1
Anfossi, G; Massucco, P; Mattiello, L; Russo, I; Trovati, M1
Belik, J; Jankov, RP; Pan, J; Tanswell, AK1
Ban, H; Gunduz, M; Haisa, M; Nakajo, T; Naomoto, Y; Nobuhisa, T; Shigemitsu, K; Takaoka, M; Tanaka, N; Yamatsuji, T1
Slomiany, A; Slomiany, BL1
Baker, JE; Fu, X; Gross, GJ; Hsu, A; Strande, JL; Su, J1
Lazarovici, P; Lecht, S; Routhu, KV; Strande, JL1

Other Studies

12 other study(ies) available for omega-n-methylarginine and wortmannin

ArticleYear
Nitric oxide stimulates skeletal muscle glucose transport through a calcium/contraction- and phosphatidylinositol-3-kinase-independent pathway.
    Diabetes, 1997, Volume: 46, Issue:11

    Topics: 3-O-Methylglucose; Androstadienes; Animals; Calcium; Dantrolene; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Female; Glucose; Indazoles; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Wortmannin

1997
Transduction pathways involved in rapid hormone receptor regulation in the mammary epithelium.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Androstadienes; Animals; Calcimycin; Cell Membrane; Cyclic GMP; Down-Regulation; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Female; Gene Products, env; Genistein; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Models, Biological; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Receptors, Prolactin; Signal Transduction; Up-Regulation; Vanadates; Wortmannin

1998
Mechanisms of 17 beta-oestradiol induced vasodilatation in isolated pressurized rat small arteries.
    British journal of pharmacology, 2000, Volume: 129, Issue:3

    Topics: Androstadienes; Animals; Coronary Vessels; Cycloheximide; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Fulvestrant; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pressure; Protein Synthesis Inhibitors; Rats; Rats, Inbred WKY; Receptors, Estrogen; Vasodilation; Wortmannin

2000
Vascular endothelial growth factor up-regulates ICAM-1 expression via the phosphatidylinositol 3 OH-kinase/AKT/Nitric oxide pathway and modulates migration of brain microvascular endothelial cells.
    The Journal of biological chemistry, 2000, Jul-07, Volume: 275, Issue:27

    Topics: Androstadienes; Animals; Brain; Cell Movement; Cells, Cultured; Endothelial Growth Factors; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Lymphokines; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

2000
Phosphorylation of eNOS initiates excessive NO production in early phases of portal hypertension.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: Adrenergic alpha-1 Receptor Agonists; Androstadienes; Animals; Enzyme Inhibitors; Hypertension, Portal; Ligation; Male; Mesenteric Artery, Superior; Methoxamine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphorylation; Portal Vein; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Wortmannin

2002
Modulation of CYP3A4 expression by ceramide in human colon carcinoma HT-29 cells.
    Biochemical and biophysical research communications, 2002, Nov-15, Volume: 298, Issue:5

    Topics: Androstadienes; Ceramides; Colonic Neoplasms; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gene Expression; Humans; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodeoxyribonucleotides, Antisense; omega-N-Methylarginine; Phosphoinositide-3 Kinase Inhibitors; S-Nitroso-N-Acetylpenicillamine; Sphingomyelin Phosphodiesterase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Wortmannin

2002
Comparison between the effects of the rapid recombinant insulin analog Lispro (Lys B28, Pro B29) and those of human regular insulin on platelet cyclic nucleotides and aggregation.
    Thrombosis research, 2003, Mar-15, Volume: 109, Issue:5-6

    Topics: Adenosine Diphosphate; Adult; Androstadienes; Blood Platelets; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Insulin; Insulin Lispro; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Recombinant Proteins; Wortmannin

2003
A bronchial epithelium-derived factor reduces pulmonary vascular tone in the newborn rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 2004, Volume: 96, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Androstadienes; Animals; Animals, Newborn; Bronchi; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Indazoles; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphoinositide-3 Kinase Inhibitors; Potassium Chloride; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Wortmannin

2004
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.
    International journal of molecular medicine, 2004, Volume: 13, Issue:4

    Topics: Androstadienes; Animals; Arginine; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Immunoblotting; Intestines; Intracellular Signaling Peptides and Proteins; Leucine; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Wortmannin

2004
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 1

    Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin

2004
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
    Basic research in cardiology, 2007, Volume: 102, Issue:4

    Topics: Androstadienes; Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hirudins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Recombinant Proteins; Research Design; RNA, Messenger; Signal Transduction; Thrombin; Time Factors; Ventricular Function, Left; Wortmannin

2007
Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.
    Journal of basic and clinical physiology and pharmacology, 2013, Volume: 24, Issue:1

    Topics: Androstadienes; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Myocardial Reperfusion Injury; Nerve Growth Factor; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Wortmannin

2013