Page last updated: 2024-09-03

omega-n-methylarginine and verapamil

omega-n-methylarginine has been researched along with verapamil in 15 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(verapamil)
Trials
(verapamil)
Recent Studies (post-2010) (verapamil)
4,41134433617,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (73.33)18.2507
2000's4 (26.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calver, A; Collier, J; Vallance, P1
Hori, M; Karaki, H; Sudjarwo, SA1
Bozhko, AP; Solodkov, AP1
Banitt, P; Creager, MA; Lipson, DE; Rongen, GA; Smits, P; Williams, SB1
Bodelsson, G; Stjernquist, M1
Hori, M; Karaki, H; Okada, T; Sudjarwo, SA; Takai, M; Urade, Y1
Badr, KF; Fukunaga, M; Katoh, T; Takahashi, K1
Das, P; Schurman, DJ; Smith, RL1
Cook, DI; Poronnik, P; Tuch, BE; Weinhaus, AJ1
Drop, LJ; Kaufmann, MA; Pargger, H1
Burchell, B; Butler, R; Morris, AD; Struthers, AD1
Brett, SE; Chowienczyk, PJ; Coltart, DJ; Kneale, BJ; Ritter, JM1
Butler, R; Morris, AD; Struthers, AD1
Baltrons, MA; GarcĂ­a, A; Pedraza, CE1
Haberberger, RV; Henrich, M; Kummer, W; Lips, KS1

Trials

1 trial(s) available for omega-n-methylarginine and verapamil

ArticleYear
Cigarette smoking in men and vascular responsiveness.
    British journal of clinical pharmacology, 2001, Volume: 52, Issue:2

    Topics: Acetylcholine; Adolescent; Adult; Angiotensin I; Angiotensin II; Blood Flow Velocity; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Plethysmography; Receptors, Endothelin; Smoking; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

2001

Other Studies

14 other study(ies) available for omega-n-methylarginine and verapamil

ArticleYear
Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes.
    The Journal of clinical investigation, 1992, Volume: 90, Issue:6

    Topics: Acetylcholine; Adult; Arginine; Arm; Diabetes Mellitus, Type 1; Humans; Male; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Verapamil

1992
Effect of endothelin-3 on cytosolic calcium level in vascular endothelium and on smooth muscle contraction.
    European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3

    Topics: Amino Acid Sequence; Animals; Aorta, Thoracic; Arginine; Calcium; Cytosol; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Wistar; Verapamil

1992
[Effect of endogenous metabolites on autoregulation and dilational reserve of coronary vessels].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:5

    Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Captopril; Coronary Circulation; Coronary Vessels; Eicosanoids; Female; In Vitro Techniques; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Vasodilation; Verapamil

1993
Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans.
    Circulation, 1995, Oct-15, Volume: 92, Issue:8

    Topics: Adenosine; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Potassium Channels; Quinidine; Regional Blood Flow; Tolbutamide; Vasodilation; Vasodilator Agents; Verapamil

1995
Characterization of endothelin receptors and localization of 125I-endothelin-1 binding sites in human umbilical artery.
    European journal of pharmacology, 1993, Nov-16, Volume: 249, Issue:3

    Topics: Arginine; Binding Sites; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Humans; Iodine Radioisotopes; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; omega-N-Methylarginine; Peptides, Cyclic; Receptors, Endothelin; Umbilical Arteries; Vasoconstriction; Vasoconstrictor Agents; Verapamil; Viper Venoms

1993
Induction of endothelium-dependent relaxation in the rat aorta by IRL 1620, a novel and selective agonist at the endothelin ETB receptor.
    British journal of pharmacology, 1993, Volume: 109, Issue:2

    Topics: Animals; Aorta, Thoracic; Arginine; Calcium; Carbachol; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Potassium Chloride; Rats; Rats, Wistar; Receptors, Endothelin; Verapamil

1993
Studies on the glomerular microcirculatory actions of manidipine and its modulation of the systemic and renal effects of endothelin.
    American heart journal, 1993, Volume: 125, Issue:2 Pt 2

    Topics: Animals; Arginine; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Endothelins; Glomerular Filtration Rate; Hemodynamics; Kidney Glomerulus; Male; Microcirculation; Nitric Oxide; Nitrobenzenes; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Vasodilation; Verapamil

1993
Nitric oxide and G proteins mediate the response of bovine articular chondrocytes to fluid-induced shear.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1997, Volume: 15, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cartilage, Articular; Cattle; Enzyme Inhibitors; Glycosaminoglycans; GTP-Binding Proteins; Neomycin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Pertussis Toxin; Protein Synthesis Inhibitors; Signal Transduction; Stress, Mechanical; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil; Virulence Factors, Bordetella; Weight-Bearing

1997
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
    Diabetologia, 1997, Volume: 40, Issue:4

    Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Mice, Transgenic; Molsidomine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreatic Neoplasms; Potassium Channels; Potassium Chloride; Tumor Cells, Cultured; Verapamil

1997
Renal vascular hyperresponsiveness to elevated ionized calcium in spontaneously hypertensive rat kidneys.
    Intensive care medicine, 1998, Volume: 24, Issue:1

    Topics: Animals; Calcium; Calcium Channel Blockers; Enzyme Inhibitors; Hypertension; In Vitro Techniques; omega-N-Methylarginine; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renal Circulation; Time Factors; Verapamil

1998
DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:5

    Topics: Acetylcholine; Adult; Analysis of Variance; Cross-Sectional Studies; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Genotype; Humans; Linear Models; Male; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Smoking; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Verapamil

1999
Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature.
    Journal of the American College of Cardiology, 2000, Volume: 36, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol; Blood Flow Velocity; Brachial Artery; Enzyme Inhibitors; Female; Forearm; Humans; Injections, Intra-Arterial; Male; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Plethysmography; Propranolol; Receptors, Adrenergic, beta-2; Reference Values; Sex Characteristics; Substance P; Vascular Resistance; Vasodilation; Vasodilator Agents; Verapamil

2000
Interleukin-1beta stimulates cyclic GMP efflux in brain astrocytes.
    FEBS letters, 2001, Nov-02, Volume: 507, Issue:3

    Topics: Animals; Astrocytes; Biological Transport; Brain; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Interleukin-1; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Probenecid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Verapamil

2001
Nicotinic receptor alpha 7-subunits are coupled to the stimulation of nitric oxide synthase in rat dorsal root ganglion neurons.
    Histochemistry and cell biology, 2003, Volume: 120, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Calcium Channels; Cell Communication; Cyclic GMP; Ganglia, Spinal; Mecamylamine; Neurons; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Receptors, Drug; Receptors, Nicotinic; TRPV Cation Channels; Verapamil

2003