Page last updated: 2024-09-03

omega-n-methylarginine and thiourea

omega-n-methylarginine has been researched along with thiourea in 20 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(thiourea)
Trials
(thiourea)
Recent Studies (post-2010) (thiourea)
4,4113443366,959461,737

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)thiourea (IC50)
UreaseCanavalia ensiformis (jack bean)0.56
Serine-protein kinase ATMHomo sapiens (human)0.2
Serine/threonine-protein kinase ATRHomo sapiens (human)0.2

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (50.00)18.2507
2000's8 (40.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brink, C; Gorenne, I; Labat, C; Norel, X; Ortiz, JL; Verley, J1
Frey, C; Griffith, OW; Gross, SS; Masters, BS; McMillan, K; Narayanan, K; Spack, L1
Abu-Soud, HM; Clark, P; Feldman, PL; Stuehr, DJ1
Griffith, OW; Joly, GA; Kilbourn, RG; Narayanan, K1
Thiemermann, C1
Griffith, OW; Kilbourn, RG1
García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA1
Araki, A; Sendo, F; Uchida, T; Yamashita, T1
Mayhan, WG; Patel, KP1
Barker, DM; Corder, R1
Holt, PG; Sly, PD; Tulić, MK; Wale, JL1
Gilroy, DW; Paul-Clark, MJ; Tomlinson, A; Willis, D; Willoughby, DA1
Abid, A; Cipolletta, C; Jouzeau, J; Nédélec, E; Netter, P; Presle, N; Terlain, B1
Beresewicz, A; Maczewski, M1
Chinje, EC; Goodyer, CL; Jaffar, M; Stratford, IJ; Threadgill, MD1
Costello, AL; Fast, W; Stone, EM; Tierney, DL1
Brett, SE; Casadei, B; Chowienczyk, PJ; Seddon, MD; Shah, AM1
Cohen, O; Kfir-Erenfeld, S; Sionov, RV; Spokoini, R; Yefenof, E; Zilberman, Y1
Brett, S; Casadei, B; Chowienczyk, P; Melikian, N; Seddon, M; Shabeeh, H; Shah, AM1
Casadei, B; Chowienczyk, P; Dworakowski, R; Melikian, N; Shabeeh, H; Shah, AM1

Reviews

1 review(s) available for omega-n-methylarginine and thiourea

ArticleYear
Selective inhibition of the activity of inducible nitric oxide synthase in septic shock.
    Progress in clinical and biological research, 1995, Volume: 392

    Topics: Animals; Arginine; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Shock, Septic; Thiourea

1995

Other Studies

19 other study(ies) available for omega-n-methylarginine and thiourea

ArticleYear
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pulmonary Artery; Receptors, Histamine; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Thiourea

1992
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.
    The Journal of biological chemistry, 1994, Oct-21, Volume: 269, Issue:42

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Citrulline; Cytochrome c Group; Heme; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thiourea

1994
Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cells, Cultured; Citrulline; Cloning, Molecular; Electrons; Heme; Humans; Iron; Kinetics; NADP; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Thiourea

1994
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents

1995
Nitric oxide synthase inhibitors: amino acids.
    Methods in enzymology, 1996, Volume: 268

    Topics: Amino Acids; Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rodentia; Structure-Activity Relationship; Thiourea

1996
Bacterial infection induces nitric oxide synthase in human neutrophils.
    The Journal of clinical investigation, 1997, Jan-01, Volume: 99, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections

1997
Nitric oxide is an effector molecule in inhibition of tumor cell growth by rIFN-gamma-activated rat neutrophils.
    International journal of cancer, 1997, Apr-10, Volume: 71, Issue:2

    Topics: Animals; Catalase; Cell Division; Cytotoxicity Tests, Immunologic; Enzyme Inhibitors; Free Radical Scavengers; Interferon-gamma; Male; Neutrophil Activation; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Rats; Recombinant Proteins; Superoxide Dismutase; Thiourea; Tumor Cells, Cultured

1997
Treatment with dimethylthiourea prevents impaired dilatation of the basilar artery during diabetes mellitus.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Acetylcholine; Animals; Basilar Artery; Diabetes Mellitus, Experimental; Free Radical Scavengers; Male; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Streptozocin; Substance P; Thiourea; Vasodilation; Vasodilator Agents

1998
Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: Acetylcholine; Amphibian Proteins; Animals; Aorta, Thoracic; Corticotropin-Releasing Hormone; Deoxycholic Acid; Detergents; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Peptide Hormones; Peptides; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium; Thiourea; Vasodilation; Vasodilator Agents

1999
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
    The European respiratory journal, 2000, Volume: 15, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea

2000
Nitric oxide synthase inhibitors have opposite effects on acute inflammation depending on their route of administration.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-15, Volume: 166, Issue:2

    Topics: Acute Disease; Amidines; Animals; Antioxidants; Benzylamines; Carrageenan; Disease Models, Animal; Drug Administration Schedule; Edema; Enzyme Inhibitors; Free Radical Scavengers; Inflammation; Inflammation Mediators; Injections; Injections, Intraperitoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pleura; Pleurisy; Rats; Rats, Wistar; Superoxides; Thiourea

2001
Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism.
    Biochemical pharmacology, 2001, Apr-15, Volume: 61, Issue:8

    Topics: Animals; Cartilage; Chondrocytes; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Isoenzymes; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Rats; Rats, Wistar; Sulfonamides; Thiourea

2001
Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
    European journal of pharmacology, 2003, Feb-14, Volume: 461, Issue:2-3

    Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radicals; Guanidines; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Rats; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sulfones; Thiourea; Ventricular Function, Left

2003
Time-dependence and preliminary SAR studies in inhibition of nitric oxide synthase isoforms by homologues of thiocitrulline.
    Bioorganic & medicinal chemistry letters, 2003, Nov-03, Volume: 13, Issue:21

    Topics: Animals; Citrulline; Enzyme Inhibitors; Humans; Indicators and Reagents; Isoenzymes; Kinetics; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thiourea

2003
Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa.
    Biochemistry, 2006, May-02, Volume: 45, Issue:17

    Topics: Amidohydrolases; Binding Sites; Citrulline; Cobalt; Cysteine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Lysine; Mass Spectrometry; Models, Chemical; omega-N-Methylarginine; Protons; Pseudomonas aeruginosa; Spectrophotometry, Ultraviolet; Spectrum Analysis; Thiourea; X-Rays; Zinc

2006
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.
    Circulation, 2008, Apr-15, Volume: 117, Issue:15

    Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Citrulline; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stress, Psychological; Thiourea; Vasodilation; Vasomotor System

2008
Nitric oxide cooperates with glucocorticoids in thymic epithelial cell-mediated apoptosis of double positive thymocytes.
    International immunology, 2009, Volume: 21, Issue:10

    Topics: Animals; Apoptosis; Coculture Techniques; Enzyme Inhibitors; Epithelial Cells; Glucocorticoids; Hormone Antagonists; Interferon-gamma; Interleukin-1alpha; Interleukin-1beta; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mifepristone; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Receptors, Glucocorticoid; Thiourea; Thymus Gland; Up-Regulation

2009
Sympathetic activation increases NO release from eNOS but neither eNOS nor nNOS play an essential role in exercise hyperemia in the human forearm.
    American journal of physiology. Heart and circulatory physiology, 2013, Volume: 304, Issue:9

    Topics: Adult; Blood Pressure; Citrulline; Forearm; Hand Strength; Humans; Hyperemia; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Physical Exertion; Regional Blood Flow; Sympathetic Nervous System; Thiourea; Vasoconstriction

2013
Differential role of endothelial versus neuronal nitric oxide synthase in the regulation of coronary blood flow during pacing-induced increases in cardiac workload.
    American journal of physiology. Heart and circulatory physiology, 2013, Volume: 304, Issue:9

    Topics: Blood Pressure; Citrulline; Coronary Circulation; Coronary Vessels; Female; Heart Rate; Humans; Male; Middle Aged; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Thiourea; Vasodilation

2013