Page last updated: 2024-09-03

omega-n-methylarginine and sirolimus

omega-n-methylarginine has been researched along with sirolimus in 4 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(sirolimus)
Trials
(sirolimus)
Recent Studies (post-2010) (sirolimus)
4,41134433620,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badger, AM; Bugelski, PJ; Kaplan, JM; Newman-Tarr, T; Olivera, DL; Ruggieri, EV1
Ban, H; Gunduz, M; Haisa, M; Nakajo, T; Naomoto, Y; Nobuhisa, T; Shigemitsu, K; Takaoka, M; Tanaka, N; Yamatsuji, T1
Carreira, RS; Glembotski, CC; Gottlieb, RA; Huang, C; Iwai-Kanai, E; Perry, CN; Yuan, H1
Bi, Y; Chen, W; Chu, Y; Liu, G; Liu, H; Lu, Y; Wang, R; Wang, X; Yang, H; Yang, R; Zhang, Y; Zhang, Z1

Other Studies

4 other study(ies) available for omega-n-methylarginine and sirolimus

ArticleYear
Inhibition of lymphoproliferative responses by SK&F 105685, a novel anti-arthritic agent.
    Journal of clinical & laboratory immunology, 1991, Volume: 36, Issue:4

    Topics: Animals; Arginine; Arthritis; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; omega-N-Methylarginine; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Spiro Compounds; Spleen; Time Factors; Tumor Cells, Cultured

1991
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.
    International journal of molecular medicine, 2004, Volume: 13, Issue:4

    Topics: Androstadienes; Animals; Arginine; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Immunoblotting; Intestines; Intracellular Signaling Peptides and Proteins; Leucine; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Wortmannin

2004
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:2

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Autophagy; Cells, Cultured; Cytoprotection; Enzyme Inhibitors; Glutathione; Hydrogen Peroxide; Imidazoles; Lipopolysaccharides; Mice; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Signal Transduction; Sirolimus; Tumor Necrosis Factor-alpha; Tyrphostins

2009
Targeting S1P1 receptor protects against murine immunological hepatic injury through myeloid-derived suppressor cells.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Apr-01, Volume: 192, Issue:7

    Topics: Animals; CD11b Antigen; Cell Differentiation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Female; Fingolimod Hydrochloride; Immunoblotting; Immunosuppressive Agents; Liver; Male; Mice; Mice, Inbred C57BL; Myeloid Cells; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Propylene Glycols; Receptors, Chemokine; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sirolimus; Sphingosine; T-Lymphocytes, Regulatory; Th1 Cells; TOR Serine-Threonine Kinases

2014