Page last updated: 2024-09-03

omega-n-methylarginine and simvastatin

omega-n-methylarginine has been researched along with simvastatin in 4 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(simvastatin)
Trials
(simvastatin)
Recent Studies (post-2010) (simvastatin)
4,4113443368,4421,7303,630

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)simvastatin (IC50)
photoreceptor-specific nuclear receptorHomo sapiens (human)1.164
transactivating tegument protein VP16 [Human herpesvirus 1]Human alphaherpesvirus 1 (Herpes simplex virus type 1)4.426
Bile salt export pumpHomo sapiens (human)10
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.7843
ATP-dependent translocase ABCB1Homo sapiens (human)9.5
Insulin receptor Rattus norvegicus (Norway rat)0.0034
Prostaglandin G/H synthase 2Homo sapiens (human)0.0034
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0111
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.049
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)6.7

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Bruin, TW; Koomans, HA; Rabelink, TJ; Stroes, ES1
Green, D; O'Driscoll, G; Taylor, RR1
Fujita, H; Morita, I; Murota, S; Nagao, M; Sano, M; Sato-Suzuki, I1
Boegehold, MA; Nurkiewicz, TR1

Trials

1 trial(s) available for omega-n-methylarginine and simvastatin

ArticleYear
Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month.
    Circulation, 1997, Mar-04, Volume: 95, Issue:5

    Topics: Acetylcholine; Anticholesteremic Agents; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Nitroprusside; omega-N-Methylarginine; Placebos; Plethysmography; Regional Blood Flow; Simvastatin; Time Factors; Vasodilator Agents

1997

Other Studies

3 other study(ies) available for omega-n-methylarginine and simvastatin

ArticleYear
Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication.
    Lancet (London, England), 1995, Aug-19, Volume: 346, Issue:8973

    Topics: Adult; Arginine; Blood Pressure; Cholesterol; Cholestyramine Resin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Forearm; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Infusions, Intravenous; Lovastatin; Male; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Serotonin; Simvastatin; Vasodilation

1995
NO is not involved in the simvastatin induced cell division and differentiation in PC12 cells.
    Neuroscience letters, 1998, Feb-27, Volume: 243, Issue:1-3

    Topics: Animals; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intermediate Filament Proteins; Membrane Glycoproteins; Nerve Tissue Proteins; Neurites; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; PC12 Cells; Peripherins; Rats; Simvastatin

1998
Calcium-independent release of endothelial nitric oxide in the arteriolar network: onset during rapid juvenile growth.
    Microcirculation (New York, N.Y. : 1994), 2004, Volume: 11, Issue:6

    Topics: Animals; Arterioles; Blood Pressure; Calcimycin; Calcium Signaling; Endothelium, Vascular; Enzyme Inhibitors; Ionophores; Male; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Simvastatin; Stress, Mechanical; Vascular Endothelial Growth Factor A; Vasodilation

2004