omega-n-methylarginine has been researched along with sapropterin in 34 studies
| Studies (omega-n-methylarginine) | Trials (omega-n-methylarginine) | Recent Studies (post-2010) (omega-n-methylarginine) | Studies (sapropterin) | Trials (sapropterin) | Recent Studies (post-2010) (sapropterin) |
|---|---|---|---|---|---|
| 4,411 | 344 | 336 | 2,362 | 93 | 614 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (47.06) | 18.2507 |
| 2000's | 17 (50.00) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Böhme, E; Heinzel, B; John, M; Klatt, P; Mayer, B | 1 |
| Datto, GA; Wolff, DJ | 1 |
| Billiar, TR; Di Silvio, M; Freeswick, P; Geller, DA; Gross, SS; Nussler, A; Simmons, RL | 1 |
| Billiar, TR; Di Silvio, M; Freeswick, PD; Geller, DA; Lancaster, JR; Liu, ZZ; Lowenstein, CL; Nussler, AK; Simmons, RL; Sweetland, MA | 1 |
| Doppler, W; Fuchs, D; Goossen, B; Grünewald, K; Hentze, MW; Pantopoulos, K; Wachter, H; Weiss, G; Werner-Felmayer, G | 1 |
| McCreedy, SA; Reif, DW | 1 |
| Kim, YM; Lancaster, JR | 1 |
| Lancaster, JR; Wachter, H; Werner-Felmayer, G | 1 |
| Rosenblum, WI | 1 |
| Cosentino, F; Erkelens, W; Kastelein, J; Koomans, H; Lüscher, T; Rabelink, T; Stroes, E; Wever, R | 1 |
| Garver, RI; Haddad, IY; Hong, J; Matalon, S; Sorscher, EJ; Tzeng, E | 1 |
| Geyer, O; Mittag, T; Podos, SM | 1 |
| Ishii, M; Momose, K; Shimizu, S; Yamamoto, T | 1 |
| Daff, S; Sagami, I; Sato, H; Shimizu, T | 1 |
| McMurtry, IF; Rodman, DM; Sato, K | 1 |
| Bhagat, K; Charles, IG; Hingorani, AD; Palacios, M; Vallance, P | 1 |
| Brockhoff, C; Heitzer, T; Henne, S; Mayer, B; Meinertz, T; Mollnau, H; Münzel, T; Warnholtz, A | 1 |
| Albers, S; Heitzer, T; Krohn, K; Meinertz, T | 1 |
| Aldershvile, J; Boesgaard, S; Gruhn, N | 1 |
| Tiefenbacher, CP | 1 |
| Haramaki, N; Ikeda, H; Imaizumi, T; Kanaya, S; Murohara, T | 1 |
| Conrad, KP; Davis, AK; Novak, J; Powers, RW | 1 |
| Chayama, K; Fukuda, Y; Matsuda, K; Matsuura, H; Teragawa, H; Yamagata, T | 1 |
| Klapperstück, T; Podhaisky, HP; Riemschneider, S; Wohlrab, W | 1 |
| Himi, N; Hirano, K; Kajiya, F; Miyasaka, T; Mochizuki, S; Nakamoto, H; Ogasawara, Y; Takemoto, M; Tsujioka, K | 1 |
| Dominguez, H; Hermann, T; Ihlemann, N; Køber, L; Perner, A; Rask-Madsen, C; Torp-Pedersen, C | 1 |
| Hashimoto, R; Kitagami, T; Miura, H; Nabeshima, T; Ohta, T; Yamada, K | 1 |
| Esberg, LB; Ren, J | 1 |
| Cardounel, AJ; Xia, Y; Zweier, JL | 1 |
| Chayama, K; Goto, C; Hara, K; Higashi, Y; Jitsuiki, D; Kimura, M; Nakagawa, K; Noma, K; Oshima, T; Sasaki, S; Yoshizumi, M | 1 |
| Akasaka, T; Goto, M; Ikejima, H; Imanishi, T; Kobayashi, K; Kuroi, A; Mochizuki, S; Yoshida, K | 1 |
| Cardounel, AJ; Chen, CA; Druhan, LJ; Forbes, SP; Pope, AJ; Zweier, JL | 1 |
| Gordh, T; Miclescu, A | 1 |
| Hobbs, AJ; Sand, CA | 1 |
2 review(s) available for omega-n-methylarginine and sapropterin
| Article | Year |
|---|---|
Nitric oxide and pain: 'Something old, something new'.
Topics: Animals; Biopterins; Cyclic AMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nociceptors; omega-N-Methylarginine; Pain; Prostaglandin-Endoperoxide Synthases; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction | 2009 |
The nuances of NO synthase regulation in sepsis: Could targeting BH4 be the answer?
Topics: Animals; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypotension; Nitric Oxide Synthase; omega-N-Methylarginine; Sepsis | 2016 |
2 trial(s) available for omega-n-methylarginine and sapropterin
| Article | Year |
|---|---|
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
Topics: Adult; Antioxidants; Arginine; Biopterins; Endothelium; Female; Forearm; Humans; Hypercholesterolemia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Serotonin; Vasoconstriction; Vasodilation | 1997 |
Tetrahydrobiopterin restores endothelial dysfunction induced by an oral glucose challenge in healthy subjects.
Topics: Administration, Oral; Antioxidants; Biopterins; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Free Radical Scavengers; Glucose; Heart Rate; Humans; Hyperglycemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Postprandial Period; Regional Blood Flow; Serotonin; Vasodilation | 2003 |
30 other study(ies) available for omega-n-methylarginine and sapropterin
| Article | Year |
|---|---|
Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Calcium; Calmodulin; Citrulline; Hydrogen Peroxide; NADP; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1992 |
Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoradiography; Biopterins; Blotting, Western; Brain; Calmodulin; Cattle; Cells, Cultured; Chromatography, DEAE-Cellulose; Citrulline; Enzyme Activation; Kinetics; NADH Dehydrogenase; Nitric Oxide Synthase; Nitroarginine; Nitroblue Tetrazolium; omega-N-Methylarginine; Pituitary Gland | 1992 |
Inducible nitric oxide synthase activity in hepatocytes is dependent on the coinduction of tetrahydrobiopterin synthesis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Cytokines; Enzyme Induction; Gene Expression; GTP Cyclohydrolase; Hypoxanthines; Lipopolysaccharides; Liver; Methotrexate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger | 1993 |
Hepatocyte inducible nitric oxide synthesis is influenced in vitro by cell density.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cell Count; Cells, Cultured; Cyclic GMP; Cytokines; Humans; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Stimulation of IRE-BP activity of IRF by tetrahydrobiopterin and cytokine dependent induction of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cell Line; Chloramphenicol O-Acetyltransferase; Deferoxamine; Humans; Interferon-gamma; Iron; Iron-Regulatory Proteins; Kinetics; Leukemia, Myeloid, Acute; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA Probes; RNA-Binding Proteins; Transfection; Tumor Cells, Cultured | 1994 |
N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Biopterins; Brain; In Vitro Techniques; Isoenzymes; Kinetics; Male; Models, Biological; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Tetrahydrobiopterin-dependent nitrite oxidation to nitrate in isolated rat hepatocytes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Cytosol; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1993 |
Coinduction of nitric oxide synthesis and intracellular nonheme iron-nitrosyl complexes in murine cytokine-treated fibroblasts.
Topics: Animals; Arginine; Biopterins; Cytokines; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Fibroblasts; Hypoxanthines; Interferon-gamma; Iron; Lipopolysaccharides; Mice; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Tetrahydrobiopterin, a cofactor for nitric oxide synthase, produces endothelium-dependent dilation of mouse pial arterioles.
Topics: Animals; Antioxidants; Arterioles; Biopterins; Cerebral Arteries; Endothelium, Vascular; Male; Mice; Mice, Inbred ICR; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Pia Mater; Vasodilation | 1997 |
Modulation of adenovirus-mediated gene transfer by nitric oxide.
Topics: 3T3 Cells; Adenoviruses, Human; Animals; Antioxidants; beta-Galactosidase; Biopterins; Cell Survival; Cyclic GMP; Enzyme Inhibitors; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Humans; Luciferases; Lung; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Pteridines; Pterins; Transfection | 1997 |
Nitric oxide synthase activity in tissues of the bovine eye.
Topics: Animals; Antioxidants; Biopterins; Calmodulin; Canavanine; Cattle; Chelating Agents; Choroid; Ciliary Body; Edetic Acid; Enzyme Inhibitors; Female; Guanidines; Male; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Retina; Trabecular Meshwork | 1997 |
Reduction by tetrahydrobiopterin of H2O2-induced endothelial cell injury.
Topics: Animals; Arginine; Biopterins; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Ionomycin; omega-N-Methylarginine; Pteridines; Pterins; Rats; Serotonin | 1998 |
Autoxidation rates of neuronal nitric oxide synthase: effects of the substrates, inhibitors, and modulators.
Topics: Animals; Arginine; Biopterins; Flow Injection Analysis; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Onium Compounds; Oxidation-Reduction; Rats; Spectrophotometry | 1998 |
Hypoxia inhibits increased ETB receptor-mediated NO synthesis in hypertensive rat lungs.
Topics: Animals; Arginine; Biopterins; Egtazic Acid; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Luminescent Measurements; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Time Factors | 1999 |
Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS.
Topics: Adult; Arginine; Biopterins; Bradykinin; Endothelium, Vascular; Enzyme Inhibitors; Female; Gene Expression; Guanidines; Humans; Interleukin-1; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Shock, Septic; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase.
Topics: Acetylcholine; Antioxidants; Ascorbic Acid; Biopterins; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Serotonin; Smoking; Vasodilation | 2000 |
Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus.
Topics: Acetylcholine; Biopterins; Blood Flow Velocity; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Vasodilation; Vasodilator Agents | 2000 |
Tetrahydrobiopterin improves endothelium-dependent vasodilation in nitroglycerin-tolerant rats.
Topics: Animals; Biopterins; Blood Pressure; Drug Tolerance; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Vasodilation | 2001 |
Tetrahydrobiopterin: a critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction?
Topics: Animals; Arginine; Biopterins; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Humans; Hypercholesterolemia; In Vitro Techniques; Infusions, Intra-Arterial; Ionophores; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pteridines; Pterins; Reactive Oxygen Species; Species Specificity; Substance P; Swine; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Intraplatelet tetrahydrobiopterin plays an important role in regulating canine coronary arterial thrombosis by modulating intraplatelet nitric oxide and superoxide generation.
Topics: Animals; Biopterins; Blood Platelets; Coronary Thrombosis; Cyclic GMP; Dogs; Enzyme Inhibitors; Hemodynamics; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; P-Selectin; Platelet Aggregation; Superoxides; Tyrosine | 2001 |
Citrulline is not the major product using the standard "NOS activity" assay on renal cortical homogenates.
Topics: Animals; Antioxidants; Arginine; Biopterins; Calcium; Carbon Radioisotopes; Chelating Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Citrulline; Egtazic Acid; Enzyme Inhibitors; Female; Guanidines; Humans; Kidney Cortex; Male; Mice; Mice, Inbred Strains; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Placenta; Rats; Rats, Long-Evans; Tritium | 2002 |
Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia.
Topics: Acetylcholine; Aged; Antioxidants; Biopterins; Blood Flow Velocity; Coronary Angiography; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypercholesterolemia; Infusions, Intra-Arterial; Laser-Doppler Flowmetry; Male; Middle Aged; Nitroglycerin; omega-N-Methylarginine; Vasodilator Agents | 2002 |
Evidence for a role of nitric oxide in the mediation of antiproliferative UVA effects in keratinocytes.
Topics: Antioxidants; Biopterins; Cell Division; Cell Survival; Cells, Cultured; Cyclic N-Oxides; DNA; Dose-Response Relationship, Radiation; Free Radical Scavengers; Humans; Imidazoles; Keratinocytes; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ultraviolet Rays | 2002 |
Evaluation of basic performance and applicability of a newly developed in vivo nitric oxide sensor.
Topics: Acetylcholine; Animals; Antioxidants; Arginine; Biopterins; Calibration; Electrodes; Enzyme Inhibitors; Equipment Design; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Oxygen; Permeability; Rats; Rats, Inbred WKY; Vasodilator Agents | 2002 |
Mechanism of systemically injected interferon-alpha impeding monoamine biosynthesis in rats: role of nitric oxide as a signal crossing the blood-brain barrier.
Topics: Animals; Biogenic Monoamines; Biopterins; Blood-Brain Barrier; Brain; Brain Chemistry; Drug Administration Routes; Enzyme Inhibitors; Immunologic Factors; Interferon-alpha; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Signal Transduction | 2003 |
Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes.
Topics: Animals; Biopterins; Calcium; Cells, Cultured; Enzyme Inhibitors; Free Radical Scavengers; Glucose; Intracellular Membranes; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Ventricular Dysfunction | 2003 |
Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Humans; Magnetics; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Spin Trapping; Superoxides; Time Factors; Transfection | 2005 |
Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Aging; Biopterins; Endothelium, Vascular; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Vasodilation | 2006 |
Effects of pioglitazone on nitric oxide bioavailability measured using a catheter-type nitric oxide sensor in angiotensin II-infusion rabbit.
Topics: Acetylcholine; Angiotensin II; Animals; Biopterins; Biosensing Techniques; Blood Pressure; Calibration; Catheterization; Enzyme Inhibitors; Heart Rate; Hypoglycemic Agents; Immunohistochemistry; Male; Nitric Oxide; omega-N-Methylarginine; Pioglitazone; PPAR gamma; Rabbits; Thiazolidinediones; Tyrosine; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Regulation of eNOS-derived superoxide by endogenous methylarginines.
Topics: Arginine; Biopterins; Electron Spin Resonance Spectroscopy; Heme; Humans; NADP; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Superoxides | 2008 |