Page last updated: 2024-09-03

omega-n-methylarginine and s-methylthiocitrulline

omega-n-methylarginine has been researched along with s-methylthiocitrulline in 9 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(s-methylthiocitrulline)
Trials
(s-methylthiocitrulline)
Recent Studies (post-2010) (s-methylthiocitrulline)
4,411344336111131

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)s-methylthiocitrulline (IC50)
Nitric oxide synthase, endothelialHomo sapiens (human)0.4
Nitric oxide synthase, brainHomo sapiens (human)0.06
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)0.06
Nitric oxide synthase, inducibleHomo sapiens (human)0.3

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB1
Fast, W; Hong, L1
Fast, W; Hu, S; Monzingo, AF; Robertus, JD; Schaller, TH; Wang, Y1
Griffith, OW; Joly, GA; Kilbourn, RG; Narayanan, K1
Holt, PG; Sly, PD; Tulić, MK; Wale, JL1
Costello, AL; Fast, W; Stone, EM; Tierney, DL1
Brett, SE; Casadei, B; Chowienczyk, PJ; Seddon, MD; Shah, AM1
Brett, S; Casadei, B; Chowienczyk, P; Melikian, N; Seddon, M; Shabeeh, H; Shah, AM1
Casadei, B; Chowienczyk, P; Dworakowski, R; Melikian, N; Shabeeh, H; Shah, AM1

Other Studies

9 other study(ies) available for omega-n-methylarginine and s-methylthiocitrulline

ArticleYear
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats

1999
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia.
    The Journal of biological chemistry, 2007, Nov-30, Volume: 282, Issue:48

    Topics: Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Drug Design; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Sequence Homology, Amino Acid; Substrate Specificity

2007
Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
    Biochemistry, 2009, Sep-15, Volume: 48, Issue:36

    Topics: Amidines; Amidohydrolases; Crystallography, X-Ray; Drug Delivery Systems; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type I; Ornithine; Recombinant Proteins; Substrate Specificity; Thiourea

2009
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents

1995
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
    The European respiratory journal, 2000, Volume: 15, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea

2000
Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa.
    Biochemistry, 2006, May-02, Volume: 45, Issue:17

    Topics: Amidohydrolases; Binding Sites; Citrulline; Cobalt; Cysteine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Lysine; Mass Spectrometry; Models, Chemical; omega-N-Methylarginine; Protons; Pseudomonas aeruginosa; Spectrophotometry, Ultraviolet; Spectrum Analysis; Thiourea; X-Rays; Zinc

2006
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.
    Circulation, 2008, Apr-15, Volume: 117, Issue:15

    Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Citrulline; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stress, Psychological; Thiourea; Vasodilation; Vasomotor System

2008
Sympathetic activation increases NO release from eNOS but neither eNOS nor nNOS play an essential role in exercise hyperemia in the human forearm.
    American journal of physiology. Heart and circulatory physiology, 2013, Volume: 304, Issue:9

    Topics: Adult; Blood Pressure; Citrulline; Forearm; Hand Strength; Humans; Hyperemia; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Physical Exertion; Regional Blood Flow; Sympathetic Nervous System; Thiourea; Vasoconstriction

2013
Differential role of endothelial versus neuronal nitric oxide synthase in the regulation of coronary blood flow during pacing-induced increases in cardiac workload.
    American journal of physiology. Heart and circulatory physiology, 2013, Volume: 304, Issue:9

    Topics: Blood Pressure; Citrulline; Coronary Circulation; Coronary Vessels; Female; Heart Rate; Humans; Male; Middle Aged; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Thiourea; Vasodilation

2013