Page last updated: 2024-09-03

omega-n-methylarginine and papaverine

omega-n-methylarginine has been researched along with papaverine in 11 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(papaverine)
Trials
(papaverine)
Recent Studies (post-2010) (papaverine)
4,4113443366,027305355

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)papaverine (IC50)
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10ARattus norvegicus (Norway rat)0.076
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.3
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)8.8
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)1.7
Bile salt export pumpHomo sapiens (human)10
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.6
Cytochrome P450 2C19Homo sapiens (human)0.762
Serine hydroxymethyltransferase, mitochondrialHomo sapiens (human)2.6915
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)9
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.4
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)7.2444
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)1.03
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)9
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)0.697
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Rattus norvegicus (Norway rat)0.036
Phosphodiesterase Sus scrofa (pig)0.62
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)0.07

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galligan, JJ; Osthaus, LE1
Iadecola, C1
Dinerman, JL; Lawson, DL; Mehta, JL1
Grbović, L; Jovanović, A; Tulić, I1
Andrews, FJ; Malcontenti-Wilson, C; O'Brien, PE1
Augusto, O; Barbeiro, HV; Carvalho, MH; da-Luz, PL; Laurindo, FR; Pedro, MA1
Hanada, H; Kudo, S; Mikuniya, A; Okubo, T; Okumura, K; Suto, N1
Kelm, M; Preik, M; Preik-Steinhoff, H; Strauer, BE1
Lee, BH; Rapoport, RM; Zuccarello, M1
Hiraga, H; Okubo, T; Okumura, K; Suto, N; Yamamoto, T; Yoshida, IM1
Deussen, A; Feelisch, M; Kelm, M; Lauer, T; Preik, M; Rassaf, T; Strauer, BE1

Trials

1 trial(s) available for omega-n-methylarginine and papaverine

ArticleYear
Serum nitrite sensitively reflects endothelial NO formation in human forearm vasculature: evidence for biochemical assessment of the endothelial L-arginine-NO pathway.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Acetylcholine; Adult; Analysis of Variance; Arginine; Arteriosclerosis; Biomarkers; Endothelium, Vascular; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Papaverine; Regional Blood Flow; Regression Analysis; Vasodilator Agents

1999

Other Studies

10 other study(ies) available for omega-n-methylarginine and papaverine

ArticleYear
Antagonists of nitric oxide synthesis inhibit nerve-mediated relaxations of longitudinal muscle in guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guinea Pigs; Ileum; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Papaverine

1992
Does nitric oxide mediate the increases in cerebral blood flow elicited by hypercapnia?
    Proceedings of the National Academy of Sciences of the United States of America, 1992, May-01, Volume: 89, Issue:9

    Topics: Animals; Arginine; Brain; Hypercapnia; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Papaverine; Rats; Rats, Inbred Strains; Regional Blood Flow

1992
Interactions between nitroglycerin and endothelium in vascular smooth muscle relaxation.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2

    Topics: Animals; Arginine; Endothelium, Vascular; Epinephrine; Indomethacin; Male; Muscle, Smooth, Vascular; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Papaverine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasoconstriction; Vasodilation

1991
Predominant role for nitric oxide in the relaxation induced by acetylcholine in human uterine artery.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:3

    Topics: Acetylcholine; Adult; Amino Acid Oxidoreductases; Arginine; Arteries; Endothelium, Vascular; Female; Humans; Methylene Blue; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papaverine; Phenylephrine; Tetraethylammonium; Tetraethylammonium Compounds; Uterus; Vasodilation

1994
Protection against gastric ischemia-reperfusion injury by nitric oxide generators.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Cell Movement; Gastric Mucosa; Male; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Papaverine; Rats; Reperfusion Injury

1994
Nonspecific blockade of vascular free radical signals by methylated arginine analogues.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1998, Volume: 31, Issue:6

    Topics: Animals; Aorta, Thoracic; Arteries; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Free Radicals; Male; omega-N-Methylarginine; Papaverine; Rabbits; Vasodilator Agents

1998
A study on the effects of endogenous nitric oxide on coronary blood flow, myocardial oxygen extraction and cardiac contractility.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1

    Topics: Animals; Arginine; Coronary Circulation; Dogs; Enzyme Inhibitors; Hemodynamics; Myocardial Contraction; Myocardium; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Papaverine; Systole; Vasodilation; Vasodilator Agents

1999
Hypocapnic constriction in rabbit basilar artery in vitro: triggering by N(G)-monomethyl-L-arginine monoacetate and dependence on endothelin-1 and alkalosis.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: Acetylcholine; Alkalies; Alkalosis; Animals; Basilar Artery; Carbon Dioxide; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Hypocapnia; In Vitro Techniques; Male; Oligopeptides; omega-N-Methylarginine; Papaverine; Piperidines; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Solutions; Vasoconstriction; Vasodilation; Vasodilator Agents

2000
Nitric oxide donor FK409 and 8-bromoguanosine-cyclic monophosphate attenuate cardiac contractility assessed by Emax.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Coronary Circulation; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Myocardial Contraction; Myocardium; Nitric Oxide Donors; Nitro Compounds; omega-N-Methylarginine; Papaverine; Propranolol; Vasodilation; Vasodilator Agents; Ventricular Function, Left

2001
Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Oct-23, Volume: 98, Issue:22

    Topics: Acetylcholine; Adult; Female; Forearm; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Papaverine; Regional Blood Flow; Vasodilation

2001