omega-n-methylarginine has been researched along with nitroarginine in 238 studies
| Studies (omega-n-methylarginine) | Trials (omega-n-methylarginine) | Recent Studies (post-2010) (omega-n-methylarginine) | Studies (nitroarginine) | Trials (nitroarginine) | Recent Studies (post-2010) (nitroarginine) |
|---|---|---|---|---|---|
| 4,411 | 344 | 336 | 3,935 | 11 | 175 |
| Protein | Taxonomy | omega-n-methylarginine (IC50) | nitroarginine (IC50) |
|---|---|---|---|
| Nitric oxide synthase, endothelial | Bos taurus (cattle) | 1.2 | |
| Nitric oxide synthase, endothelial | Homo sapiens (human) | 0.38 | |
| Nitric oxide synthase, brain | Homo sapiens (human) | 1.265 | |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | 4.12 | |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | 0.5 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 6.2 | |
| Nitric oxide synthase, brain | Mus musculus (house mouse) | 0.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.42) | 18.7374 |
| 1990's | 213 (89.50) | 18.2507 |
| 2000's | 21 (8.82) | 29.6817 |
| 2010's | 3 (1.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, KM; Cowart, M; Daanen, JF; Kerwin, JF; Kohlhaas, KL; Kowaluk, EA; Wagenaar, FL | 1 |
| Burnette, TC; Collins, JL; Duffy, C; Furfine, ES; Garvey, EP; Lee, S; Oplinger, JA; Salter, M; Shearer, BG | 1 |
| Bergmanis, AA; Branson, LF; Connor, JR; Currie, MG; Fok, KF; Hagen, TJ; Hallinan, EA; Jerome, GM; Kornmeier, CM; Kramer, SW; Manning, PT; Moore, WM; Pitzele, BS; Schmelzer, AE; Swenton, L | 1 |
| Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB | 1 |
| Burton, G; Hillmann, M; Hölscher, P; Jaroch, S; McDonald, FM; Rehwinkel, H; Sülzle, D | 1 |
| Ido, M; Kawasaki, M; Matsumoto, M; Terauchi, H; Ueda, S; Yano, A | 1 |
| Beitz, E; Clement, B; Kotthaus, J; Muschick, N; Schade, D | 1 |
| Hawker, DD; Jansen Labby, K; Mataka, JJ; Silverman, RB; Trippier, PC | 1 |
| Moncada, S; Mulligan, MS; Ward, PA | 1 |
| Goy, MF; McGehee, DS; Oxford, GS | 1 |
| Balashov, SA; Kartamyshev, SP; Khaiutin, VM; Klimachev, AN; Mel'kumiants, AM | 1 |
| Conrad, KP; Whittemore, SL | 1 |
| Galligan, JJ; Osthaus, LE | 1 |
| Ishii, K; Murad, F; Schmidt, HH; Sheng, H; Warner, TD | 1 |
| Böhme, E; Heinzel, B; John, M; Klatt, P; Mayer, B | 1 |
| Catravas, JD; Marczin, N; Ryan, US | 1 |
| Datto, GA; Wolff, DJ | 1 |
| Bogle, RG; Mann, GE; Moncada, S; Pearson, JD | 1 |
| Gribkoff, VK; Lum-Ragan, JT | 1 |
| Föstermann, U; Mitchell, JA; Murad, F; Nakane, M; Pollock, JS; Schmidt, HH; Sheng, H | 1 |
| Cocks, T; Crack, P | 1 |
| Kontos, HA; Kukreja, R; Wei, EP | 1 |
| Beckmann, R; Goessl, C; Knispel, HH | 2 |
| Archer, SL; Hampl, V | 1 |
| Brink, C; Gorenne, I; Labat, C; Norel, X; Ortiz, JL; Verley, J | 1 |
| Christensen, G; Kiil, F; Kirkebøen, KA; Naess, PA | 2 |
| Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T | 1 |
| Gray, DW; Marshall, I | 1 |
| Hecker, M; Macarthur, H; Sessa, WC; Siegle, I; Vane, JR | 1 |
| Kaley, G; Koller, A; Messina, EJ; Rodenburg, JM; Wolin, MS | 1 |
| Iadecola, C | 1 |
| Nelson, GH; Nishimura, H; Rosenblum, WI | 1 |
| Benz, AM; Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| Dembińska-Kieć, A; Pallapies, D; Peskar, BA; Simmet, T; Thelen, K | 1 |
| Chaudhuri, G; Cuevas, JM; Ignarro, LJ; Vargas, HM | 1 |
| East, SJ; Garthwaite, J | 1 |
| Busse, R; Jackson, WF | 1 |
| Boeckxstaens, GE; Bogers, JJ; Bult, H; De Man, JG; Herman, AG; Oosterbosch, L; Pelckmans, PA; Van Maercke, YM | 1 |
| Desai, KM; Sessa, WC; Vane, JR | 1 |
| Knowles, RG; Moncada, S; Palacios, M; Palmer, RM | 1 |
| Breese, KR; Heistad, DD; Lopez, JA; Mügge, A; Piegors, DJ | 1 |
| Jansson, L; Sandler, S | 1 |
| de Groot, H; Komarov, P; Sies, H; Wang, JF | 1 |
| Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO | 1 |
| Madison, DV; Schuman, EM | 1 |
| Murad, F; Schmidt, HH | 1 |
| Fujiwara, S; Fukui, M; Iwaki, T; Kanaide, H; Moriguchi, M; Natori, Y; Takeshita, I | 1 |
| Andersson, KE; Forman, A; Garcia Pascual, A; Persson, K; Tøttrup, A | 1 |
| Brewer, AS; Brockman, DE; Langdon, G; Myatt, L | 1 |
| Cicala, C; Cirino, G; Regoli, D; Sorrentino, L | 1 |
| Gibson, IF; Gillespie, JS; Liu, XR; Martin, W | 1 |
| Baron, BM; Cheng, HC; Doherty, NS; Lambert, LE; McDonald, IA; Whitten, JP | 1 |
| Thiemermann, C; Vane, JR; Walder, CE | 1 |
| Cappelli-Bigazzi, M; Lamping, KG; Nuno, DW | 1 |
| Helgren, MC; Klabunde, RE; Ritger, RC | 1 |
| Barbanti, G; Giuliani, S; Maggi, CA; Turini, D | 1 |
| Ramwell, PW; Thomas, G | 1 |
| Boeckxstaens, GE; Bult, H; De Man, JG; Herman, AG; Pelckmans, PA; Van Maercke, YM | 1 |
| Estrada, C; González, C | 1 |
| Li, CG; Rand, MJ | 1 |
| al-Swayeh, OA; Evans, R; Moore, PK | 1 |
| Keist, R; Keller, R; Leist, TP; van der Meide, PH; Wechsler, A | 1 |
| Förstermann, U; Gorsky, LD; Ishii, K; Murad, F | 2 |
| Chang, B; Huang, ZJ; Ishii, K; Kerwin, JF; Murad, F | 1 |
| Cain, DA; Lawson, DL; Mehta, JL; Mehta, P; Nicolini, FA; Schreier, H | 1 |
| Harris, HJ; Hecker, M; Katsura, M; Mitchell, JA; Thiemermann, C; Vane, JR | 1 |
| al-Swayeh, OA; Chong, NW; Evans, RA; Gibson, A; Moore, PK | 1 |
| Gibson, A; Hobbs, AJ; Mirzazadeh, S; Moore, PK | 1 |
| Aisaka, K; Griffith, OW; Gross, SS; Jaffe, EA; Levi, R; Stuehr, DJ | 1 |
| Baba, H; Okamura, T; Toda, N | 1 |
| Harada, Y; Nagao, T; Ohara, F; Yamazaki, J | 1 |
| Grant, SK; Green, BG; Harrison, RK; Niedzwiecki, L; Robertson, CA | 1 |
| Agostini, J; Kalb, RG | 1 |
| Courtois, Y; Goureau, O; Hicks, D | 1 |
| Brunner, F; Klatt, P; Mayer, B; Schmidt, K | 1 |
| Frew, JD; Martin, W; Paisley, K | 1 |
| Edwards, RM; Trizna, W | 1 |
| Friedlander, MJ; Gancayco, CD; Marchase, RB; Montague, PR; Winn, MJ | 1 |
| Mizusawa, H; Omote, M | 1 |
| Cappendijk, SL; de Vries, R; Dzoljic, MR | 1 |
| Ayres, M; Chelly, F; Joly, GA; Kilbourn, RG | 1 |
| Burgess, GM; Harvey, JS | 1 |
| Amado, JA; Berrazueta, JR; Poveda, JJ; Salas, E; Sánchez de Vega, MJ | 1 |
| Acuña, C; Alonso, JM; Cudeiro, J; Martinez-Conde, S; Rivadulla, C; Rodriguez, R | 1 |
| Dokita, S; Nishimoto, T; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| Baydoun, AR; Mann, GE | 1 |
| Junien, JL; Pascaud, X; Porreca, F; Rao, RK; Riviere, PJ | 1 |
| Currie, MG; Herman, LE; Wrenn, RW | 1 |
| Klatt, P; Mayer, B; Schmidt, K | 2 |
| Kilbinger, H; Wolf, D | 1 |
| Bult, H; De Meyer, GR; Herman, AG; Jordaens, FH; Kockx, M; Ustünes, L; Zonnekeyn, LL | 1 |
| Cocks, TM; Kilpatrick, EV | 1 |
| Grooms, SY; Jones, LS | 1 |
| Cunha, FQ; Silva, JS; Vespa, GN | 1 |
| Brown, JF; Hanson, PJ; Whittle, BJ; Williams, JM | 1 |
| Koizumi, T; Miyachi, Y; Yamada, T | 1 |
| Basha, F; Carter, GW; Esumi, H; Hokari, A; Klinghofer, V; Marsden, PA; Nakane, M; Ogura, T; Pollock, JS | 1 |
| Momose, K; Nomoto, M; Shimizu, S; Yamamoto, T | 1 |
| Barclay, JK; Woodley, NE | 1 |
| Billek, M; Nöll, GN; Pietruck, C; Schmidt, KF | 1 |
| Benicourt, C; Junien, JL; Lockhart, BP; Privat, A | 1 |
| Drapier, JC; Hirling, H; Kaldy, P; Kühn, LC; Wietzerbin, J | 1 |
| Klatt, P; List, BM; Mayer, B; Schmidt, K | 1 |
| Cardoso, SA; Carvalho, AP; Lopes, MC; Schousboe, A | 1 |
| Barjavel, MJ; Bhargava, HN | 1 |
| Mehta, JL; Yang, BC | 1 |
| Basha, F; Budzik, GP; Carter, GW; Donnelly, JL; Klinghofer, V; Kuk, JE; Nakane, M; Pollock, JS | 1 |
| Gold, R; Hartung, HP; Jung, S; Liew, FY; Toyka, KV; Zielasek, J | 1 |
| Bonfoco, E; Ceccatelli, S; Manzo, L; Nicotera, P | 1 |
| Clavier, N; Izuta, M; Kirsch, JR; Traystman, RJ | 1 |
| McCreedy, SA; Reif, DW | 1 |
| Babbedge, RC; Hart, SL; Moore, PK | 1 |
| Abe, K; Mizutani, A; Saito, H | 1 |
| Brading, A; Mortensen, N; O'Kelly, T | 1 |
| Bonhomme, E; Laubie, M; Simonet, S; Verbeuren, TJ | 1 |
| Nelson, GH; Rosenblum, WI; Shimizu, T | 1 |
| Guarner, F; Malagelada, JR; Molero, X; Moncada, S; Mourelle, M | 1 |
| Asante, NK; Cain, SM; Curtis, SE; Vallet, B; Winn, MJ | 1 |
| Brzozowski, T; Konturek, SJ; Majka, J; Pytko-Polonczyk, J; Stachura, J | 1 |
| Klatt, P; Mayer, B; Schmid, M; Schmidt, K | 1 |
| Belenky, SN; Gossman, GL; Nelson, KJ; Rennard, SI; Robbins, RA; Rubinstein, I | 1 |
| Pfaffendorf, M; Van Meel, JC; Van Zwieten, PA; Zhang, J | 1 |
| Cocks, TM; Stork, AP | 1 |
| Lamkin, GE; Lasser, EC | 1 |
| Dacey, RG; Dietrich, HH; Kimura, M | 1 |
| Calixto, JB; Schlemper, V | 1 |
| Forrest, CR; Pang, CY; Xu, N | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Evora, PR; Pearson, PJ; Schaff, HV | 1 |
| Gukovskaya, A; Pandol, S | 1 |
| Ilebekk, A; Kirkebøen, KA; Naess, PA; Offstad, J | 1 |
| Izumi, Y; Zorumski, CF | 1 |
| Kaneko, K; Sunano, S | 1 |
| Choi, DW; Corbett, JA; Hewett, SJ; McDaniel, ML | 1 |
| Morin, FC; Tiktinsky, MH | 1 |
| Asensio, VC; Falanga, PB; Oshima, H | 1 |
| Gibson, IF; Gillespie, JS; Martin, W | 1 |
| Kurtz, A; Scholz, H | 1 |
| Chen, D; Herve, P; Mace, L; Nottin, R; Qi, X; Weiss, M | 1 |
| Coffey, RG; Fitzpatrick, DF; Hirschfield, SL | 1 |
| Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E | 1 |
| Bauer, AJ; Sarr, MG; Stark, ME; Szurszewski, JH | 1 |
| Bennett, T; Gardiner, SM | 1 |
| Hashimoto, S; Kigoshi, S; Muramatsu, I | 1 |
| Goodman, LW; Rubin, LJ; Tod, ML; Tseng, CM | 1 |
| Kaley, G; Koller, A; Messina, EJ; Sun, D | 1 |
| Dananberg, J; Grekin, RJ; Sider, RS | 1 |
| Förstermann, U; Ishii, K; Murad, F; Sheng, H | 1 |
| Béa, ML; Berdeaux, A; Ghaleh, B; Giudicelli, JF; Puybasset, L; Simon, L | 1 |
| Girton, ME; Oldfield, EH; Pluta, RM; Thompson, BG | 1 |
| Chang, MJ; Johnson, CS; Modzelewski, RA; Russell, DM | 1 |
| Fujihara, N; Hattori, M; Kojima, I; Sakamoto, K | 1 |
| Fukushima, S; Hashimoto, M; Ishida, Y; Isokawa, S; Masumura, S; Momose, K; Murakami, E; Nakayama, K; Sasaki, T; Tamura, K | 1 |
| Baudouin, JE; Tachon, P | 1 |
| Kirk, A; Nicholls, DJ; Wallace, AV | 1 |
| Acu-na, C; Cudeiro, J; Grieve, KL; Martinez, L; Martinez-Conde, S; Rivadulla, C; Rodriguez, R | 1 |
| Connor, MP; Salzman, AL; Southan, GJ; Szabó, C; Thiemermann, C | 1 |
| Boje, KM; Korytko, PJ | 1 |
| Kimes, AS; London, ED; Vaupel, DB | 1 |
| de Carvalho, RP; de Faria, MH; do Nascimento, JL; Hokoç, JN | 1 |
| Butterworth, RF; Rao, VL | 1 |
| Gieseler, RK; Gröne, EF; Gröne, HJ; Klanke, B; Schlemminger, R; Stojanovic, T; Tsikas, D | 1 |
| Griffith, OW; Kilbourn, RG | 1 |
| Masters, BS; McMillan, K; Salerno, JC | 1 |
| Costa, G; García-Pascual, A; Labadia, A; Persson, K; Triguero, D | 1 |
| Bhargava, HN; Zhao, GM | 1 |
| Lam, TT; Tso, MO | 1 |
| Esplugues, JV; Martinez-Cuesta, MA; Whittle, BJ | 1 |
| Dawson, TM; Gillespie, DC; Ruthazer, ES; Snyder, SH; Stryker, MP | 1 |
| Angelo, S; Boyd, CA; Devés, R; Forray, MI | 1 |
| Bhargava, HN; Thorat, SN | 1 |
| Kontos, HA; Wei, EP | 1 |
| Sontheimer, H; Ye, ZC | 1 |
| Chesnais, JM; Fischmeister, R; Hartzell, HC; Hove-Madsen, L; Méry, PF | 1 |
| García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| Higashino, H; Lambev, I; Simeonova, K; Suzuki, A | 1 |
| Leinders-Zufall, T; Zufall, F | 1 |
| Cook, DI; Poronnik, P; Tuch, BE; Weinhaus, AJ | 1 |
| González-Macías, J; Riancho, JA; Salas, E; Zarrabeitia, MT | 1 |
| Ashcroft, FM; Coles, B; Gummerson, N; Proks, P; Sakura, H; Smith, PA | 1 |
| Arrigo, LM; Bhagat, DD; Cowman, MK; Dweck, HS; Ghael, D; Li, M; Rosenfeld, L; Vilar, RE | 1 |
| Deliconstantinos, G; Stavrides, JC; Villiotou, V | 1 |
| Handy, RL; Moore, PK | 1 |
| Béa, ML; Berdeaux, A; Beverelli, F; Giudicelli, JF; Puybasset, L | 1 |
| Khawaja, AM; Page, CP; Paul, W; Perez, AC | 1 |
| Ellory, JC; Hanssen, H; Kiessling, K; Mann, GE; Mendes Ribeiro, AC; Roberts, NB | 1 |
| DeGeorge, GL; Heck, DE; Laskin, JD | 1 |
| Martásek, P; Masters, BS; Salerno, JC; Williams, RF | 1 |
| Abdullah, K; Cawley, T; Connolly, C; Docherty, JR; Ruiz, E | 1 |
| Berdeaux, A; Béverelli, F; Giudicelli, JF; Puybasset, L | 1 |
| Chaudhry, GM; Esakof, DD; Hariawala, M; Horowitz, JR; Isner, JM; Rivard, A; Sheriff, DD; Symes, JF; van der Zee, R | 1 |
| Alloatti, G; Bosia, A; Costamagna, C; Gallo, MP; Ghigo, D; Levi, RC; Penna, C | 1 |
| Evora, PR; Pearson, PJ; Schaff, HV; Seccombe, JF | 1 |
| da Silva, CA; Del Bel, EA; Guimarães, FS | 1 |
| Discigil, B; Evora, PR; Pearson, PJ; Schaff, HV | 1 |
| Barnhart, DC; Mulholland, MW; Sarosi, GA; Zhang, W | 1 |
| Costa, A; Forsling, ML; Grossman, AB; Kostoglou-Athanassiou, I; Nappi, G; Navarra, P | 1 |
| Kim, CK; Rivier, C | 1 |
| Carmo, A; Carvalho, AP; Cruz, MT; Lopes, MC | 1 |
| Kula, P; Kurmanowska, Z; Nowak, D; Stolarek, R | 1 |
| Balligand, JL; Bril, A; Gauthier, C; Khandoudi, N; Kobzik, L; Le Marec, H; Leblais, V; Trochu, JN | 1 |
| Choate, JK; Paterson, DJ; Sears, CE | 1 |
| Jia, Y; Martin, JG; Tolloczko, B; Zacour, M | 1 |
| Itoh, M; Iwata, F; Joh, T; Yokoyama, Y | 1 |
| Hayashi, H; Sanae, F | 1 |
| Clarkson, RB; Cruz, L; Gillette, R; Moroz, LL; Norby, SW; Sweedler, JV | 1 |
| Bruce, KH; Craft, B; Harkin, AJ; Paul, IA | 1 |
| Atkins, CM; Sweatt, JD | 1 |
| Noris, M; Remuzzi, G | 1 |
| Coffa, FP; Kotecha, N | 1 |
| Burnett, JC; Miller, VM; Rabelink, T; Wennberg, PW | 1 |
| Addicks, K; Andressen, C; Bloch, W; Fleischmann, BK; Hescheler, J; Hops, B; Lorke, DE | 1 |
| Badin, RA; Bersier, G; Boveris, A; Bustamante, J; Romero, M | 1 |
| Furusawa, S; Sakaguchi, S; Sasaki, K; Takayanagi, M; Takayanagi, Y; Yokota, K | 1 |
| Dawson, J; Knowles, RG | 1 |
| Russell, RJ | 1 |
| Beyak, MJ; Collman, PI; Diamant, NE; Valdez, DT; Xue, S | 1 |
| Bajaj-Elliott, M; Farthing, MJ; McDonald, V; Pollok, RC; Sanderson, IR | 1 |
| Smolich, JJ | 1 |
| Prado, WA; Sousa, AM | 1 |
| Karlsson, JO; Lossius, K; Persson, AA; Støen, R | 1 |
| Cartledge, JJ; Eardley, I; Joyce, AD; Minhas, S; Morrison, JF | 1 |
| Lema, SC; Nevitt, GA | 1 |
| Lundman, P; Nilsson, L; Pernow, J; Tornvall, P | 1 |
| Finci-Yeheskel, Z; Hurwitz, A; Mayer, M; Milwidsky, A | 1 |
| Kelicen, P; Miwa, I; Pekiner, C; Uma, S | 1 |
| Cao, H; Chen, XS; Wu, ZY | 1 |
| Hartshorne, GM; Kennedy, CR; Mitchell, LM | 1 |
| Chang, HY; Chen, CW; Hsiue, TR; Lee, CH | 1 |
| Faggio, C; Pidalà, P; Trischitta, F | 1 |
| Jain, R; Mohan, D; Mukherjee, K | 1 |
| Azuma, H; Imamura, M; Isotani, E; Mizuno, Y; Nagai, A; Ohno, K | 1 |
| Choe, J; Ha, KS; Jeoung, D; Kim, YM; Kwon, YG; Lee, DK; Lee, H; Lee, KS; Won, MH | 1 |
| Chen, Y; Chitapanarux, T; Melton, AC; Soon, RK; Wu, J; Yee, HF | 1 |
4 review(s) available for omega-n-methylarginine and nitroarginine
| Article | Year |
|---|---|
Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Calcium Channels; Drug Combinations; Drug Design; Humans; Huntington Disease; Neurodegenerative Diseases; Nitric Oxide Synthase Type I; Oxidative Stress; Parkinson Disease; Protein Folding; Protein Structure, Quaternary; Proteostasis Deficiencies; Receptors, N-Methyl-D-Aspartate | 2013 |
Inhibitors of nitric oxide synthase and the opioid withdrawal syndrome.
Topics: Animals; Arginine; Morphine Dependence; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Substance Withdrawal Syndrome | 1995 |
Selective inhibitors of neuronal nitric oxide synthase--is no NOS really good NOS for the nervous system?
Topics: Animals; Central Nervous System; Enzyme Inhibitors; Humans; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Structure-Activity Relationship; Substrate Specificity | 1997 |
Uremic bleeding: closing the circle after 30 years of controversies?
Topics: Anemia; Animals; Arginine; Bleeding Time; Blood Platelets; Endothelium, Vascular; Enzyme Inhibitors; Erythropoietin; Guanidines; Hemorrhage; History, 18th Century; History, 20th Century; Humans; Isoenzymes; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Succinates; Uremia | 1999 |
234 other study(ies) available for omega-n-methylarginine and nitroarginine
| Article | Year |
|---|---|
Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.
Topics: Acetylcholine; Animals; Cerebellum; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoenzymes; Kinetics; Muscle Relaxation; Neurons; Nitric Oxide Synthase; Nitro Compounds; Ornithine; Rats; Structure-Activity Relationship | 1998 |
N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
Topics: Amidines; Animals; Cerebellum; Cerebral Cortex; Enzyme Inhibitors; Furans; Humans; In Vitro Techniques; Isoenzymes; Male; Neurons; Nitric Oxide Synthase; Rats; Rats, Wistar; Structure-Activity Relationship | 1998 |
2-Iminopyrrolidines as potent and selective inhibitors of human inducible nitric oxide synthase.
Topics: Animals; Blood Pressure; Enzyme Induction; Enzyme Inhibitors; Humans; Imines; Isoenzymes; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship | 1998 |
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats | 1999 |
Dihydroquinolines with amine-containing side chains as potent n-NOS inhibitors.
Topics: Amines; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Quinolines; Recombinant Proteins; Reference Values; Structure-Activity Relationship | 2003 |
4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: a new class of orally bioavailable nitric oxide synthase inhibitor.
Topics: Administration, Oral; Animals; Biological Availability; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Oxazolidinones | 2004 |
Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads.
Topics: Amidines; Amidohydrolases; Arginine; Humans; Inhibitory Concentration 50; Kinetics; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Structure-Activity Relationship | 2008 |
Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis.
Topics: Alveolitis, Extrinsic Allergic; Amino Acid Oxidoreductases; Animals; Arginine; Immune Complex Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Peroxidase; Rats; Vasculitis, Leukocytoclastic, Cutaneous | 1992 |
Involvement of the nitric oxide-cyclic GMP pathway in the desensitization of bradykinin responses of cultured rat sensory neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Binding, Competitive; Bradykinin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electric Conductivity; Ganglia, Spinal; Neurons, Afferent; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats | 1992 |
[Nitrogen oxide is not an agent of endothelium-mediated arterial dilatation to an increase in the blood flow rate].
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Blood Flow Velocity; Blood Pressure; Cats; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Femoral Artery; Nitroarginine; Nitrogen Oxides; omega-N-Methylarginine; Vasodilation | 1992 |
NG-monomethyl-L-arginine and nitroarginine potentiate pressor responsiveness of vasoconstrictors in conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Drug Synergism; Female; NG-Nitroarginine Methyl Ester; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Vasoconstrictor Agents | 1992 |
Antagonists of nitric oxide synthesis inhibit nerve-mediated relaxations of longitudinal muscle in guinea pig ileum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guinea Pigs; Ileum; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Papaverine | 1992 |
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Calmodulin; Cell Line; Cyclic GMP; Enzyme Activation; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Islets of Langerhans; NADP; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; omega-N-Methylarginine; Rats | 1992 |
Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Calcium; Calmodulin; Citrulline; Hydrogen Peroxide; NADP; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1992 |
Endothelial cGMP does not regulate basal release of endothelium-derived relaxing factor in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasodilator Agents | 1992 |
Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoradiography; Biopterins; Blotting, Western; Brain; Calmodulin; Cattle; Cells, Cultured; Chromatography, DEAE-Cellulose; Citrulline; Enzyme Activation; Kinetics; NADH Dehydrogenase; Nitric Oxide Synthase; Nitroarginine; Nitroblue Tetrazolium; omega-N-Methylarginine; Pituitary Gland | 1992 |
Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Endothelium, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine | 1992 |
Evidence for nitric oxide synthase inhibitor-sensitive and insensitive hippocampal synaptic potentiation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Conditioning, Psychological; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred F344; Synapses | 1992 |
Characterization and localization of nitric oxide synthase in non-adrenergic non-cholinergic nerves from bovine retractor penis muscles.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Calmodulin; Cattle; Cyclic GMP; Immunohistochemistry; Male; Nerve Tissue; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penis | 1992 |
Thimerosal blocks stimulated but not basal release of endothelium-derived relaxing factor (EDRF) in dog isolated coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arginine; Arteries; Bradykinin; Calcimycin; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Thimerosal; Vasoconstrictor Agents | 1992 |
Effects in cats of inhibition of nitric oxide synthesis on cerebral vasodilation and endothelium-derived relaxing factor from acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Cats; Cerebrovascular Circulation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Sodium Dodecyl Sulfate; Vasodilation | 1992 |
Nitric oxide mediates neurogenic relaxation induced in rabbit cavernous smooth muscle by electric field stimulation.
Topics: Animals; Arginine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Penile Erection; Penis; Phenylephrine; Rabbits | 1992 |
NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
Topics: Animals; Aorta, Abdominal; Arginine; Calcimycin; Endothelium, Vascular; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1992 |
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pulmonary Artery; Receptors, Histamine; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Thiourea | 1992 |
Inhibition of renal nitric oxide synthesis with NG-monomethyl-L-arginine and NG-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Dogs; Female; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Renal Circulation | 1992 |
Role of endothelium-derived relaxing factor in the in vivo renal vascular action of adenosine in dogs.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Dogs; Female; Hemodynamics; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenethylamines; Renal Circulation; Theophylline | 1992 |
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Ibuprofen; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Role of intracellular thiols in release of EDRF from cultured endothelial cells.
Topics: Adenosine Diphosphate; Animals; Aorta; Arginine; Biological Assay; Cattle; Cells, Cultured; Cysteine; Diamide; Endothelium, Vascular; Ethylmaleimide; Glutathione; Ionomycin; Kinetics; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Sulfhydryl Compounds; Sulfhydryl Reagents | 1992 |
Regulation of arteriolar tone and responses via L-arginine pathway in skeletal muscle.
Topics: Animals; Arginine; Arterioles; Bradykinin; Dose-Response Relationship, Drug; Indomethacin; Male; Muscles; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Vasomotor System | 1992 |
Does nitric oxide mediate the increases in cerebral blood flow elicited by hypercapnia?
Topics: Animals; Arginine; Brain; Hypercapnia; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Papaverine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1992 |
L-NMMA in brain microcirculation of mice is inhibited by blockade of cyclooxygenase and by superoxide dismutase.
Topics: Animals; Arginine; Aspirin; Blood Platelets; Cell Adhesion; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Free Radical Scavengers; Indomethacin; Male; Mice; Mice, Inbred ICR; Microcirculation; Nitroarginine; omega-N-Methylarginine; Platelet Aggregation; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1992 |
Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices.
Topics: Animals; Arginine; Calcium; Hemoglobins; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Synapses | 1992 |
Effect of 3-morpholinosydnonimine (SIN-1), NG-nitro-L-arginine (NNA) and NG-monomethyl-L-arginine (NMMA) on isolated anaphylactic guinea-pig hearts.
Topics: Anaphylaxis; Animals; Arginine; Coronary Circulation; Eicosanoids; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Molsidomine; Myocardium; Nitroarginine; omega-N-Methylarginine; Ovalbumin | 1992 |
Importance of nitric oxide in canine femoral circulation: comparison of two NO inhibitors.
Topics: Acetylcholine; Animals; Arginine; Dogs; Female; Femoral Artery; Male; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Regional Blood Flow; Vasodilation | 1992 |
Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Hydralazine; In Vitro Techniques; Male; Nitrates; Nitric Acid; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Penicillamine; Phenylephrine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Sympathetic Nervous System; Vasodilation; Vasopressins | 1991 |
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Cyclic GMP; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Elevated guanosine 3':5'-cyclic monophosphate mediates the depression of nitrovasodilator reactivity in endothelium-intact blood vessels.
Topics: Animals; Aorta, Thoracic; Arginine; Cricetinae; Cyclic GMP; Endothelium, Vascular; Male; Mesocricetus; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Sodium Nitrite; Vasodilator Agents | 1991 |
Release of nitric oxide upon stimulation of nonadrenergic noncholinergic nerves in the rat gastric fundus.
Topics: Adenosine Triphosphate; Animals; Arginine; Atropine; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Vasoactive Intestinal Peptide | 1991 |
Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid.
Topics: Animals; Arginine; Food; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pressure; Reflex; Stomach | 1991 |
Kinetic characteristics of nitric oxide synthase from rat brain.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Brain; Diencephalon; Guanylate Cyclase; Kinetics; Male; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats; Synaptosomes; Telencephalon; Tissue Distribution | 1990 |
Acetylcholine-induced vasodilatation in rabbit hindlimb in vivo is not inhibited by analogues of L-arginine.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Female; Femoral Artery; Hindlimb; Male; Microspheres; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Rabbits; Regional Blood Flow; Substance P; Vascular Resistance; Vasodilation | 1991 |
The nitric oxide synthase II inhibitor NG-nitro-L-arginine stimulates pancreatic islet insulin release in vitro, but not in the perfused pancreas.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains | 1991 |
Contribution of nitric oxide synthase to luminol-dependent chemiluminescence generated by phorbol-ester-activated Kupffer cells.
Topics: Acridines; Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell-Free System; In Vitro Techniques; Kupffer Cells; Luminescent Measurements; Luminol; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats | 1991 |
A requirement for the intercellular messenger nitric oxide in long-term potentiation.
Topics: Amino Acid Oxidoreductases; Arginine; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Synaptic Membranes; Synaptic Transmission | 1991 |
Purification and characterization of a human NO synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calmodulin; Cerebellum; Chromatography, Affinity; Chromatography, Gel; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Kinetics; Molecular Weight; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Temporal Lobe; Trifluoperazine | 1991 |
Effects of L-NMMA and L-NNA on the selective ATP-induced enhancement of intratumoral blood flow.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Brain Neoplasms; Glioma; Male; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow; Tumor Cells, Cultured | 1992 |
Electrically-induced, nerve-mediated relaxation of rabbit urethra involves nitric oxide.
Topics: Animals; Arginine; Arginine Vasopressin; Dose-Response Relationship, Drug; Electric Stimulation; Endothelins; Female; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Urethra | 1992 |
Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation.
Topics: Acetylcholine; Arginine; Calcimycin; Endothelins; Female; Fetus; Humans; Nitric Oxide; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Placenta; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Vasoconstriction | 1992 |
Effect of bradykinin antagonists, NG-monomethyl-L-arginine and L-NG-nitro arginine on phospholipase A2 induced oedema in rat paw.
Topics: Animals; Arginine; Bradykinin; Edema; Evans Blue; Foot; Kininogens; Male; Methysergide; Nitroarginine; omega-N-Methylarginine; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains | 1991 |
Effects of NG-substituted analogues of L-arginine on NANC relaxation of the rat anococcygeus and bovine retractor penis muscles and the bovine penile artery.
Topics: Animals; Arginine; Arteries; Autonomic Nervous System; Cattle; Guanethidine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Muscles; Nitroarginine; omega-N-Methylarginine; Penis; Rats; Serotonin; Stereoisomerism; Vasodilation | 1991 |
Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.
Topics: Animals; Arginine; Central Nervous System; Cyclic GMP; Endothelium; In Vitro Techniques; Macrophages; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1991 |
The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat.
Topics: Animals; Arginine; Blood Pressure; Dopamine; Indomethacin; Kidney Cortex; Lasers; Male; Nitric Oxide; Nitroarginine; Nitrous Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renal Circulation | 1991 |
Evidence of a role for compounds derived from arginine in coronary response to serotonin in vivo.
Topics: Animals; Arginine; Coronary Vessels; Dinoprost; Dogs; Drug Combinations; Female; Male; Nitroarginine; omega-N-Methylarginine; Serotonin; Vasoconstriction | 1991 |
Cardiovascular actions of inhibitors of endothelium-derived relaxing factor (nitric oxide) formation/release in anesthetized dogs.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart; Hemodynamics; Indomethacin; Myocardium; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasoconstriction | 1991 |
Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum.
Topics: Arginine; Dose-Response Relationship, Drug; Humans; Ileum; In Vitro Techniques; Muscle Relaxation; Nitroarginine; omega-N-Methylarginine | 1991 |
NW-nitro L-arginine benzyl ester, a potent irreversible inhibitor of endothelium dependent relaxation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle, Smooth, Vascular; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1991 |
Basal and acetylcholine-stimulated nitric oxide formation mediates relaxation of rabbit cavernous smooth muscle.
Topics: Acetylcholine; Animals; Arginine; Atropine Derivatives; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Parasympatholytics; Penis; Rabbits | 1991 |
Non-adrenergic non-cholinergic relaxation mediated by nitric oxide in the canine ileocolonic junction.
Topics: Animals; Arginine; Autonomic Nervous System; Colon; Dogs; Electric Stimulation; Female; Hemoglobins; Ileum; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Stereoisomerism | 1990 |
Nitric oxide mediates the neurogenic vasodilation of bovine cerebral arteries.
Topics: Animals; Arginine; Cattle; Cerebral Arteries; Electric Stimulation; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Superoxide Dismutase; Tetrodotoxin; Vasodilation | 1991 |
Evidence that part of the NANC relaxant response of guinea-pig trachea to electrical field stimulation is mediated by nitric oxide.
Topics: Animals; Arginine; Autonomic Nervous System; Chymotrypsin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Trachea; Vasoactive Intestinal Peptide | 1991 |
Rabbit brain contains an endogenous inhibitor of endothelium-dependent relaxation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Brain Chemistry; Dialysis; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nerve Tissue Proteins; Nitroarginine; omega-N-Methylarginine; Rabbits; Vasodilation | 1990 |
Mechanisms of macrophage-mediated tumor cell killing: a comparative analysis of the roles of reactive nitrogen intermediates and tumor necrosis factor.
Topics: Animals; Arginine; Argininosuccinic Acid; Cell Line; Cell Survival; Humans; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages; Male; Mice; Neoplasms; Nitroarginine; omega-N-Methylarginine; Propionibacterium acnes; Rats; Tumor Necrosis Factor-alpha | 1990 |
Production of an EDRF-like activity in the cytosol of N1E-115 neuroblastoma cells.
Topics: Animals; Arginine; Cell-Free System; Cyclic GMP; Cytosol; Kinetics; Mice; Neuroblastoma; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1990 |
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation.
Topics: Adenosine Triphosphate; Animals; Arginine; Calcimycin; Cattle; Cyclic GMP; Depression, Chemical; Fibroblasts; In Vitro Techniques; Melitten; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Superoxide Dismutase | 1990 |
Evidence for generation of a large amount of nitric oxide-like vascular smooth muscle relaxant by cholesterol-rich neutrophils.
Topics: Animals; Aorta; Arginine; Calcium; Cholesterol; Humans; In Vitro Techniques; Indomethacin; Kinetics; Liposomes; Muscle Relaxation; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine.
Topics: Acetylcholine; Animals; Aorta; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rabbits | 1990 |
L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rabbits; Vasodilation | 1990 |
L-NG-monomethyl arginine and L-NG-nitro arginine inhibit non-adrenergic, non-cholinergic relaxation of the mouse anococcygeus muscle.
Topics: Animals; Arginine; Autonomic Nervous System; Electric Stimulation; In Vitro Techniques; Male; Mice; Muscle Relaxation; Muscles; Nitroarginine; omega-N-Methylarginine; Sympathetic Nervous System; Vasodilator Agents | 1990 |
Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine.
Topics: Animals; Arginine; Blood Pressure; Cattle; Cells, Cultured; Endothelium, Vascular; Guinea Pigs; Macrophages; Mice; Nitric Oxide; Nitroarginine; omega-N-Methylarginine | 1990 |
Role of nitric oxide in non-adrenergic, non-cholinergic nerve-mediated relaxation in dog duodenal longitudinal muscle strips.
Topics: Animals; Arginine; Autonomic Nervous System; Dogs; Duodenum; Electric Stimulation; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Stereoisomerism | 1990 |
The cytosol of N1E-115 neuroblastoma cells synthesizes an EDRF-like substance that relaxes rabbit aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Cytosol; Female; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Neuroblastoma; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rabbits; Superoxide Dismutase; Tumor Cells, Cultured | 1989 |
Barium and strontium can substitute for calcium in stimulating nitric oxide production in the endothelium of canine coronary arteries.
Topics: Animals; Arginine; Barium; Calcium; Cations, Divalent; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle Relaxation; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Potassium; Strontium | 1995 |
Effect of nitric oxide synthase substrate analog inhibitors on rat liver arginase.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Kinetics; Liver; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
Molecular evidence for nitric oxide-mediated motor neuron development.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Cellular Senescence; Humans; Molecular Biology; Motor Neurons; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Spinal Cord; Tissue Distribution | 1993 |
Human retinal pigmented epithelial cells produce nitric oxide in response to cytokines.
Topics: Amino Acid Oxidoreductases; Arginine; Cells, Cultured; Cycloheximide; Cytokines; Fibroblast Growth Factor 2; Humans; Interferon-gamma; Interleukin-1; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Pigment Epithelium of Eye; Recombinant Proteins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1994 |
Inhibitors of brain nitric oxide synthase. Binding kinetics, metabolism, and enzyme inactivation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Chromatography, Gel; Kinetics; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Regression Analysis; Swine | 1994 |
Selective inhibition of basal but not agonist-stimulated activity of nitric oxide in rat aorta by NG-monomethyl-L-arginine.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Endothelium, Vascular; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
Modulation of glomerular arteriolar tone by nitric oxide synthase inhibitors.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Dinoprostone; Dopamine; Female; In Vitro Techniques; Kidney Glomerulus; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Renal Circulation; Vasodilation | 1993 |
Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Indazoles; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1994 |
Phenylephrine-induced rhythmic activity in the rabbit ear artery.
Topics: Animals; Arginine; Arteries; Charybdotoxin; Ear, External; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Male; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Periodicity; Phenylephrine; Potassium Channel Blockers; Prostaglandin Antagonists; Rabbits; Scorpion Venoms; Vasoconstriction | 1993 |
Inhibitory effect of nitric oxide (NO) synthase inhibitors on naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Behavior, Animal; Diarrhea; Male; Mice; Morphine Dependence; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Substance Withdrawal Syndrome | 1993 |
Effects of NG-methyl-L-arginine, NG-nitro-L-arginine, and aminoguanidine on constitutive and inducible nitric oxide synthase in rat aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Enzyme Induction; Guanidines; Lipopolysaccharides; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Structure-Activity Relationship | 1994 |
A nitric oxide synthase inhibitor reduces desensitisation of bradykinin-induced activation of phospholipase C in sensory neurones.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Bradykinin; Bucladesine; Cells, Cultured; Enzyme Activation; Ganglia, Spinal; Inositol Phosphates; Kinetics; Neurons, Afferent; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Second Messenger Systems; Type C Phospholipases | 1993 |
Induction of nitric oxide synthase in human mammary arteries in vitro.
Topics: Amino Acid Oxidoreductases; Arginine; Endothelium, Vascular; Enzyme Induction; Glucocorticoids; Humans; In Vitro Techniques; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine | 1994 |
Modulatory influence of putative inhibitors of nitric oxide synthesis on visual processing in the cat lateral geniculate nucleus.
Topics: Amino Acid Oxidoreductases; Anesthesia; Animals; Arginine; Cats; Geniculate Bodies; Iontophoresis; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Photic Stimulation; Visual Perception | 1994 |
Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Canavanine; Cyclic GMP; Electric Stimulation; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rabbits; Urethra | 1994 |
Selective targeting of nitric oxide synthase inhibitors to system y+ in activated macrophages.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Canavanine; Carrier Proteins; Cell Line; Citrulline; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Receptors, Virus | 1994 |
Tonic regulation of mouse ileal ion transport by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Ileum; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Sodium Nitrite | 1994 |
Nitric oxide participates in the regulation of pancreatic acinar cell secretion.
Topics: Amino Acid Oxidoreductases; Amylases; Animals; Arginine; Carbachol; Cyclic AMP; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Pancreas; Rats; Rats, Wistar | 1994 |
Uptake of nitric oxide synthase inhibitors by macrophage RAW 264.7 cells.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport; Carrier Proteins; Cell Line; Interferon-gamma; Leucine; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; Sodium | 1994 |
Increase by NO synthase inhibitors of acetylcholine release from guinea-pig myenteric plexus.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Evoked Potentials; Guinea Pigs; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1994 |
Vasoconstrictor responses after neo-intima formation and endothelial removal in the rabbit carotid artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin I; Angiotensin II; Animals; Arginine; Carotid Arteries; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Rabbits; Serotonin; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1994 |
Evidence for differential roles of nitric oxide (NO) and hyperpolarization in endothelium-dependent relaxation of pig isolated coronary artery.
Topics: Animals; Arginine; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Potassium; Substance P; Swine | 1994 |
Hippocampal in vitro kindling is not blocked by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electric Stimulation; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Long-Term Potentiation; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1994 |
Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chagas Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; omega-N-Methylarginine; Spleen; Trypanosoma cruzi | 1994 |
Gastric mucosal nitric oxide synthase activity: inhibition by phosphorylation, arginine analogues and trifluoperazine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Canavanine; Gastric Mucosa; In Vitro Techniques; Kinetics; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phosphorylation; Rats; Trifluoperazine | 1994 |
Immediate arousal response and adaptation to low-dose x-rays in mouse and its disappearance by olfactory bulbectomy and nitric oxide inhibitor.
Topics: Adaptation, Physiological; Amino Acid Oxidoreductases; Animals; Arginine; Arousal; Electroencephalography; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Olfactory Bulb; omega-N-Methylarginine; Sleep | 1994 |
Functional expression of three isoforms of human nitric oxide synthase in baculovirus-infected insect cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Baculoviridae; Blotting, Western; Cell Line; Chromatography, Affinity; DNA, Complementary; Endothelium, Vascular; Enzyme Induction; Gene Expression; Guanidines; Humans; Isoenzymes; Kinetics; Mice; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Recombinant Proteins; Spodoptera; Transfection | 1995 |
Reduction by NG-nitro-L-arginine of H2O2-induced endothelial cell injury.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cattle; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Citrulline; Endothelium, Vascular; Hydrogen Peroxide; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1994 |
Nitric oxide synthase inhibitors do not alter functional hyperemia in canine skeletal muscle.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Flow Velocity; Bradykinin; Dogs; Endothelium; Female; Femoral Artery; Hyperemia; Male; Muscles; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxygen Consumption; Vasoconstriction | 1994 |
Inhibition of nitric oxide synthase alters light responses and dark voltage of amphibian photoreceptors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Darkness; Electrophysiology; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Patch-Clamp Techniques; Photic Stimulation; Photoreceptor Cells; Rana temporaria; Retinal Rod Photoreceptor Cells | 1994 |
Inhibitors of free radical formation fail to attenuate direct beta-amyloid25-35 peptide-mediated neurotoxicity in rat hippocampal cultures.
Topics: Allopurinol; Alzheimer Disease; Amino Acid Oxidoreductases; Amyloid beta-Peptides; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Embryo, Mammalian; Free Radical Scavengers; Free Radicals; Hippocampus; Humans; Indomethacin; Masoprocol; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxypurinol; Peptide Fragments; Quinacrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Xanthine Oxidase | 1994 |
Reciprocal modulation of aconitase activity and RNA-binding activity of iron regulatory factor by nitric oxide.
Topics: Aconitate Hydratase; Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Interferon-gamma; Iron-Regulatory Proteins; Leukemia P388; Lipopolysaccharides; Macrophages; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; RNA-Binding Proteins; RNA, Messenger; Tumor Cells, Cultured; Vasodilator Agents | 1994 |
Characterization of neuronal amino acid transporters: uptake of nitric oxide synthase inhibitors and implication for their biological effects.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport; Carrier Proteins; Cyclic GMP; Mice; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1995 |
Amino acids differentially inhibit the L-[3H]arginine transport and nitric oxide synthase in rat brain synaptosomes.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Biological Transport; Brain; Chick Embryo; Cytosol; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; Synaptosomes; Tritium | 1994 |
Effect of opioid receptor agonists on nitric oxide synthase activity in rat cerebral cortex homogenate.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Citrulline; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1994 |
Critical role of endothelium in sustained arterial contraction during prolonged hypoxia.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Indomethacin; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 1995 |
Novel potent and selective inhibitors of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Enzyme Induction; Isoenzymes; Isothiuronium; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Thiazines | 1995 |
Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis.
Topics: Acetates; Amino Acid Oxidoreductases; Animals; Arginine; Encephalomyelitis, Autoimmune, Experimental; Female; Guanidines; Mice; Mice, Inbred Strains; Myelin Basic Protein; Neuritis, Autoimmune, Experimental; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1995 |
Colchicine induces apoptosis in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Arginine; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Cyclosporine; Dizocilpine Maleate; DNA; Kinetics; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Paclitaxel; Rats; Rats, Sprague-Dawley; tau Proteins; Time Factors; Tubulin | 1995 |
Cerebral blood flow during inhibition of brain nitric oxide synthase activity in normal, hypertensive, and stroke-prone rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Brain; Cerebrovascular Circulation; Female; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Regional Blood Flow; Species Specificity; Structure-Activity Relationship; Vascular Resistance | 1995 |
N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Biopterins; Brain; In Vitro Techniques; Isoenzymes; Kinetics; Male; Models, Biological; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Anti-nociceptive activity of nitric oxide synthase inhibitors in the mouse: dissociation between the effect of L-NAME and L-NMMA.
Topics: Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Brain; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1993 |
Involvement of nitric oxide in long-term potentiation in the dentate gyrus in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Hippocampus; Male; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1993 |
Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide.
Topics: Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Anal Canal; Arginine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; Male; Middle Aged; Muscle Contraction; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxyhemoglobins | 1993 |
Evidence for induction of nonendothelial NO synthase in aortas of cholesterol-fed rabbits.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cholesterol, Dietary; Endothelium, Vascular; Enzyme Induction; Male; Muscle Contraction; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Serotonin | 1993 |
Endothelium-dependent effects of substance P and calcitonin gene-related peptide on mouse pial arterioles.
Topics: Animals; Arginine; Arterioles; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Evans Blue; Indomethacin; Lasers; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pia Mater; Substance P; Vasodilation | 1993 |
Regulation of gall bladder motility by the arginine-nitric oxide pathway in guinea pigs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bethanechol Compounds; Cholecystokinin; Endotoxins; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Pressure; Second Messenger Systems | 1993 |
Characterization of endothelial cell amino acid transport systems involved in the actions of nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Biological Transport; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Leucine; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1993 |
Effects of NG-substituted arginines on coronary vascular function after endotoxin.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Coronary Vessels; Dogs; Escherichia coli; Female; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Thrombin | 1993 |
Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers.
Topics: Acetates; Acetic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Gastric Mucosa; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Stomach; Stomach Ulcer | 1993 |
Reversible inactivation of endothelial nitric oxide synthase by NG-nitro-L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Endothelium, Vascular; Kinetics; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1993 |
Inhibitors of nitric oxide synthase attenuate human neutrophil chemotaxis in vitro.
Topics: Amino Acid Oxidoreductases; Arginine; Canavanine; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cyclic GMP; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Stereoisomerism | 1993 |
Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pyridines; Rabbits | 1994 |
Pharmacological reactivity of human epicardial coronary arteries: characterization of relaxation responses to endothelium-derived relaxing factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Arginine; Coronary Vessels; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Is there a role for nitric oxide in contrast material toxicity?
Topics: Animals; Arginine; Immunization; Immunoglobulin E; Iothalamate Meglumine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Ovalbumin; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Rats, Wistar | 1994 |
Nitric oxide regulates cerebral arteriolar tone in rats.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Indomethacin; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Perfusion; Rats; Rats, Sprague-Dawley; Vasomotor System | 1994 |
Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea.
Topics: Animals; Arginine; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Trachea | 1994 |
Evidence for nicotine-induced skin flap ischemic necrosis in the pig.
Topics: Animals; Arginine; Blood Pressure; Body Temperature; Cardiac Output; Catecholamines; Dermatologic Surgical Procedures; Ischemia; Microcirculation; Necrosis; Nicotine; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Regional Blood Flow; Skin; Surgical Flaps; Swine | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
Arginine vasopressin induces endothelium-dependent vasodilatation of the pulmonary artery. V1-receptor-mediated production of nitric oxide.
Topics: Animals; Arginine; Arginine Vasopressin; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pulmonary Artery; Receptors, Vasopressin; Vasodilation | 1993 |
Nitric oxide production regulates cGMP formation and calcium influx in pancreatic acinar cells.
Topics: Animals; Arginine; Calcium; Carbachol; Cyclic GMP; Guinea Pigs; Indomethacin; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreas; Rats | 1994 |
Effects of regional inhibition of nitric oxide synthesis in intact porcine hearts.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arginine; Coronary Circulation; Female; Hemodynamics; Hyperemia; Male; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen Consumption; Swine; Time Factors | 1994 |
Nitric oxide and long-term synaptic depression in the rat hippocampus.
Topics: Animals; Arginine; Carbon Monoxide; Electric Stimulation; Hemoglobins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Involvement of alpha-adrenoceptors in the endothelium-dependent depression of noradrenaline-induced contraction in rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dextrorphan; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
Increasing oxygen tension dilates fetal pulmonary circulation via endothelium-derived relaxing factor.
Topics: Animals; Arginine; Fetus; Hemodynamics; Hyperbaric Oxygenation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen; Pulmonary Circulation; Sheep; Vasodilation | 1993 |
Plasmodium berghei: is nitric oxide involved in the pathogenesis of mouse cerebral malaria?
Topics: Animals; Arginine; Disease Susceptibility; Malaria, Cerebral; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; omega-N-Methylarginine; Plasmodium berghei; Plasmodium chabaudi | 1993 |
Actions and interactions of NG-substituted analogues of L-arginine on NANC neurotransmission in the bovine retractor penis and rat anococcygeus muscles.
Topics: Animals; Arginine; Autonomic Nervous System; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitroarginine; omega-N-Methylarginine; Penis; Rats; Synaptic Transmission | 1993 |
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney.
Topics: Acetylcholine; Angiotensin I; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Perfusion; Pressure; Rats; Rats, Inbred Strains; Renin | 1993 |
Evidence of L-arginine/nitric oxide pathway in endothelium and smooth muscle of human internal mammary artery.
Topics: Acetylcholine; Aged; Arginine; Calcimycin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Kinetics; Male; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine | 1993 |
Endothelium-dependent vasorelaxing activity of wine and other grape products.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Endothelium, Vascular; Fruit; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Plant Extracts; Rats; Rats, Sprague-Dawley; Vasodilation; Wine | 1993 |
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones | 1993 |
Nitric oxide mediates inhibitory nerve input in human and canine jejunum.
Topics: Animals; Arginine; Dogs; Electric Stimulation; Female; Humans; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Species Specificity | 1993 |
Effect of arginine analogues on hemodynamic responses in conscious rats.
Topics: Animals; Arginine; Blood Pressure; Drug Synergism; Nitroarginine; omega-N-Methylarginine; Rats; Vasoconstrictor Agents | 1993 |
Nitric oxide-dependent and -independent neurogenic relaxation of isolated dog urethra.
Topics: Animals; Arginine; Autonomic Nervous System; Dogs; Electric Stimulation; Electrodes; Female; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Urethra; Vasoactive Intestinal Peptide | 1993 |
NG-monomethyl-L-arginine paradoxically relaxes preconstricted canine intrapulmonary arteries.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Endothelium, Vascular; Epoprostenol; Immunoenzyme Techniques; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Pulmonary Artery; Serotonin; Vasodilation | 1993 |
L-arginine analogues blunt prostaglandin-related dilation of arterioles.
Topics: Acetylcholine; Adenosine; Animals; Arachidonic Acids; Arginine; Arterioles; Blood Pressure; Dinoprostone; Dose-Response Relationship, Drug; Male; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Wistar; Vasodilation | 1993 |
Sustained hypertension induced by orally administered nitro-L-arginine.
Topics: Administration, Oral; Animals; Arginine; Blood Pressure; Heart Rate; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1993 |
Mechanism of bradykinin-induced cyclic GMP accumulation in bovine tracheal smooth muscle.
Topics: Animals; Arginine; Bradykinin; Calcium; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Methylene Blue; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Pyrogallol; Superoxide Dismutase; Trachea | 1995 |
[Hemodynamic effects of sub-chronic NO synthase inhibition in conscious dogs: role of EDRF/NO in muscular exertion].
Topics: Acetylcholine; Animals; Arginine; Consciousness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Physical Exertion | 1995 |
Nitric oxide mediation of chemoregulation but not autoregulation of cerebral blood flow in primates.
Topics: Animals; Arginine; Cerebrovascular Circulation; Homeostasis; Hypercapnia; Macaca mulatta; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1996 |
Interleukin 1 alpha and gamma-interferon induction of nitric oxide production from murine tumor-derived endothelial cells.
Topics: Animals; Arginine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Female; Fibrosarcoma; Interferon-gamma; Interleukin-1; Kinetics; Male; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; Time Factors | 1996 |
Nitric oxide: a modulator for the epidermal growth factor receptor expression in developing ovarian granulosa cells.
Topics: Animals; Arginine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Diethylstilbestrol; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Sexual Maturation | 1996 |
A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue.
Topics: Animals; Aorta, Thoracic; Arginine; Carbachol; Electrodes; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Oxygen; Partial Pressure; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1996 |
Constitutive nitric oxide synthase is present in normal human keratinocytes.
Topics: Arginine; Calcium; Calmodulin; Canavanine; Cells, Cultured; Cytosol; Enzyme Inhibitors; Humans; Isoenzymes; Keratinocytes; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1996 |
Reversibility of inhibition of human type II nitric oxide synthase.
Topics: Adenosine Diphosphate; Animals; Arginine; Cell Line; Colonic Neoplasms; Enzyme Inhibitors; Humans; Isoenzymes; Isothiuronium; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Onium Compounds; Tumor Cells, Cultured | 1996 |
Further observations on the role of nitric oxide in the feline lateral geniculate nucleus.
Topics: Afferent Pathways; Animals; Arginine; Cats; Electric Stimulation; Electroencephalography; Enzyme Inhibitors; gamma-Aminobutyric Acid; Geniculate Bodies; Iontophoresis; Models, Neurological; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Paralysis; Penicillamine; Photic Stimulation; S-Nitroso-N-Acetylpenicillamine; Synapses; Time Factors; Visual Fields; Visual Perception | 1996 |
Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform.
Topics: Amidines; Animals; Aorta; Arginine; Blood Pressure; Cattle; Cells, Cultured; Isoenzymes; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar | 1995 |
Pharmacological characterization of nitric oxide production in a rat model of meningitis.
Topics: Animals; Arginine; Cells, Cultured; Cerebellum; Choroid Plexus; Escherichia coli; Leukocytes; Lipopolysaccharides; Male; Meninges; Meningitis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1996 |
Development of NADPH-diaphorase in the avian retina: regulation by calcium ions and relation to nitric oxide synthase.
Topics: Animals; Arginine; Calcium; Chick Embryo; Enzyme Activation; Enzyme Inhibitors; Histocytochemistry; Ions; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Retina | 1996 |
L-[3H]nitroarginine and L-[3H]arginine uptake into rat cerebellar synaptosomes: kinetics and pharmacology.
Topics: Amino Acids; Animals; Arginine; Biological Transport; Cerebellum; Enzyme Inhibitors; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Synaptosomes; Tritium | 1996 |
Enhanced renal allograft rejection by inhibitors of nitric oxide synthase: a nonimmunologic influence on alloreactivity.
Topics: Animals; Blood Vessels; Cell Adhesion Molecules; Cyclosporine; Cytokines; Graft Rejection; Immune System; Kidney; Kidney Transplantation; Male; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred BN; Rats, Inbred Lew; Renal Circulation | 1996 |
Nitric oxide synthase inhibitors: amino acids.
Topics: Amino Acids; Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rodentia; Structure-Activity Relationship; Thiourea | 1996 |
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats | 1996 |
Characterization of nitric oxide synthase activity in sheep urinary tract: functional implications.
Topics: Animals; Dose-Response Relationship, Drug; Electrochemistry; Female; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Sheep; Ureter; Urethra | 1996 |
Nitric oxide synthase inhibition attenuates tolerance to morphine but not to [D-Ala2, Glu4] deltorphin II, a delta 2-opioid receptor agonist in mice.
Topics: Analgesia; Animals; Cerebral Ventricles; Drug Tolerance; Enzyme Inhibitors; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Morphine; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; omega-N-Methylarginine; Receptors, Opioid, delta | 1996 |
Nitric oxide synthase (NOS) inhibitors ameliorate retinal damage induced by ischemia in rats.
Topics: Animals; Cell Count; Enzyme Inhibitors; Intraocular Pressure; Ischemia; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Reperfusion Injury; Retina; Retinal Ganglion Cells | 1996 |
Modulation by nitric oxide of spontaneous motility of the rat isolated duodenum: role of tachykinins.
Topics: Animals; Drug Interactions; Duodenum; Enzyme Inhibitors; Gastrointestinal Motility; In Vitro Techniques; Isometric Contraction; Lipopolysaccharides; Male; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Neurokinin-2; Tachykinins | 1996 |
Inhibition of nitric oxide synthase does not prevent ocular dominance plasticity in kitten visual cortex.
Topics: Animals; Cats; Dominance, Cerebral; Enzyme Inhibitors; Functional Laterality; Neuronal Plasticity; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Reference Values; Vision, Monocular; Visual Cortex | 1996 |
Transport of nitric oxide synthase inhibitors through cationic amino acid carriers in human erythrocytes.
Topics: Arginine; Biological Transport; Cations; Erythrocytes; Ethylmaleimide; Humans; Kinetics; Lysine; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1995 |
Evidence for a role of nitric oxide of the central nervous system in morphine abstinence syndrome.
Topics: Animals; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Morphine Dependence; Naltrexone; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Substance Withdrawal Syndrome | 1996 |
Arginine analogues inhibit responses mediated by ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Arginine; Arterioles; Cats; Guanylate Cyclase; Hypercapnia; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pia Mater; Potassium Channel Blockers; Potassium Channels; Rats; Vasodilation | 1996 |
Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide.
Topics: Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Cytokines; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Humans; Interferon-gamma; Interleukin-1; Kinetics; Molsidomine; Neuroglia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penicillamine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1996 |
Nitric oxide synthase does not participate in negative inotropic effect of acetylcholine in frog heart.
Topics: Acetylcholine; Animals; Arginine; Calcium; Electric Conductivity; Isoproterenol; Kinetics; Muscarine; Myocardial Contraction; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Patch-Clamp Techniques; Rana catesbeiana; Rana esculenta | 1996 |
Bacterial infection induces nitric oxide synthase in human neutrophils.
Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections | 1997 |
Haemodynamic effects of NO-synthase inhibitors, NG-monomethyl-L-arginine, NG-nitro-L-arginine and NG-nitro-L-arginine methyl ester, and NO-donor, glyceryl trinitrate, in conscious SHRSP and WKY.
Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hypertension; Microspheres; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Vasodilator Agents | 1995 |
Identification of a long-lasting form of odor adaptation that depends on the carbon Monoxide/cGMP second-messenger system.
Topics: Acclimatization; Ambystoma; Aminoquinolines; Animals; Cadmium; Carbon Monoxide; Cyclic GMP; Cyclohexanols; Enzyme Inhibitors; Eucalyptol; In Vitro Techniques; Menthol; Monoterpenes; Nitroarginine; Odorants; Olfactory Receptor Neurons; omega-N-Methylarginine; Reaction Time; Second Messenger Systems; Sulfonamides; Terpenes | 1997 |
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Mice, Transgenic; Molsidomine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreatic Neoplasms; Potassium Channels; Potassium Chloride; Tumor Cells, Cultured; Verapamil | 1997 |
Impairment of osteoblast growth by nitric oxide synthase inhibitors: an effect independent of nitric oxide and arginine transport inhibition.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Osteoblasts; Rats | 1996 |
Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic beta-cells.
Topics: Alternative Splicing; Aniline Compounds; Animals; Arginine; Biological Transport; Calcium; Carrier Proteins; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Fluorescent Dyes; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Receptors, Virus; RNA, Messenger; Xanthenes | 1997 |
Nitric oxide degradation of heparin and heparan sulphate.
Topics: Animals; Cells, Cultured; Chromatography, Gel; Endothelium, Vascular; Enzyme Inhibitors; Heparin; Heparitin Sulfate; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Umbilical Veins | 1997 |
Inhibition of ultraviolet B-induced skin erythema by N-nitro-L-arginine and N-monomethyl-L-arginine.
Topics: Ammonia; Ammonium Hydroxide; Animals; Endothelium, Vascular; Enzyme Inhibitors; Erythema; Guinea Pigs; Humans; Hydroxides; Keratinocytes; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroso Compounds; omega-N-Methylarginine; Radiation Injuries; Radiation Protection; Skin; Sulfhydryl Compounds; Ultraviolet Rays | 1997 |
Chronic inhibition of NO synthase enhances the production of prostacyclin in coronary arteries through upregulation of the cyclooxygenase type 1 isoform.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Coronary Vessels; Cyclooxygenase 1; Dogs; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; In Vitro Techniques; Indans; Indomethacin; Isoenzymes; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Nitrobenzenes; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Up-Regulation | 1997 |
Persistence of effects of nitric oxide synthase inhibitors: comparisons on blood flow and plasma exudation in guinea pig skin.
Topics: Animals; Arginine; Enzyme Inhibitors; Exudates and Transudates; Guinea Pigs; Iodine Radioisotopes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Regional Blood Flow; Serum Albumin; Skin; Stereoisomerism; Vasoconstrictor Agents | 1997 |
Transport of L-arginine and the nitric oxide inhibitor NG-monomethyl-L-arginine in human erythrocytes in chronic renal failure.
Topics: Adult; Arginine; Biological Transport; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Erythrocytes; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Renal Dialysis; Uremia | 1997 |
Arginine metabolism in keratinocytes and macrophages during nitric oxide biosynthesis: multiple modes of action of nitric oxide synthase inhibitors.
Topics: Animals; Arginine; Cell Line; Citrulline; Dose-Response Relationship, Drug; Guanidines; Interferon-gamma; Keratinocytes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1997 |
Substrate and substrate analog binding to endothelial nitric oxide synthase: electron paramagnetic resonance as an isoform-specific probe of the binding mode of substrate analogs.
Topics: Animals; Arginine; Cattle; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Inhibitors; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Protein Binding; Substrate Specificity | 1997 |
Comparison of the effects of nitric oxide synthase inhibition and guanylate cyclase inhibition on vascular contraction in vitro and in vivo in the rat.
Topics: Acetylcholine; Aminoquinolines; Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; Vasoconstriction | 1997 |
Prostaglandins reduce the contractile responses to noradrenaline and angiotensin II in canine femoral arteries after but not before chronic inhibition of nitric oxide synthesis.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclooxygenase Inhibitors; Dogs; Endothelium, Vascular; Femoral Artery; Heart Rate; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine | 1997 |
Vascular endothelial growth factor/vascular permeability factor produces nitric oxide-dependent hypotension. Evidence for a maintenance role in quiescent adult endothelium.
Topics: Animals; Aorta; Cholesterol, Dietary; Diet, Atherogenic; Echocardiography; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Humans; Hypercholesterolemia; Hypotension; Lymphokines; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rabbits; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Secretory Rate; Swine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilation | 1997 |
Modulation of guinea-pig cardiac L-type calcium current by nitric oxide synthase inhibitors.
Topics: Animals; Blotting, Western; Calcium Channels; Carbachol; Citrulline; Electrophysiology; Enzyme Inhibitors; Female; Guanosine Diphosphate; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Male; Membrane Potentials; Muscarinic Antagonists; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Patch-Clamp Techniques; Thionucleotides | 1998 |
Hypomagnesemia inhibits nitric oxide release from coronary endothelium: protective role of magnesium infusion after cardiac operations.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arrhythmias, Cardiac; Bradykinin; Cardiac Output; Cardiac Surgical Procedures; Coronary Thrombosis; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Infusions, Intravenous; Magnesium; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Pericardium; Platelet Aggregation Inhibitors; Postoperative Complications; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1998 |
Catalepsy induced by nitric oxide synthase inhibitors.
Topics: Animals; Catalepsy; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1998 |
Hypoxia increases vasodilator release from internal mammary artery and saphenous vein grafts.
Topics: Animals; Coronary Artery Bypass; Coronary Circulation; Cyclooxygenase Inhibitors; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Hypoxia; Indomethacin; Mammary Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Saphenous Vein; Tunica Intima; Vascular Patency; Vasodilation | 1998 |
Endothelin-stimulated capacitative calcium entry in enteric glial cells: synergistic effects of protein kinase C activity and nitric oxide.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channels; Carcinogens; Cells, Cultured; Drug Synergism; Endothelin-3; Enzyme Inhibitors; Guinea Pigs; Myenteric Plexus; Neuroglia; Nickel; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penicillamine; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Endotoxin stimulates an endogenous pathway regulating corticotropin-releasing hormone and vasopressin release involving the generation of nitric oxide and carbon monoxide.
Topics: Animals; Carbon Monoxide; Cells, Cultured; Corticotropin-Releasing Hormone; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hypothalamus; Immune System; Lipopolysaccharides; Male; Metalloporphyrins; Neurosecretory Systems; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Protoporphyrins; Rats; Rats, Wistar; Vasopressins | 1998 |
Influence of nitric oxide synthase inhibitors on the ACTH and cytokine responses to peripheral immune signals.
Topics: Adrenocorticotropic Hormone; Animals; Cytokines; Enzyme Inhibitors; Immune System; Interleukin-1; Interleukin-6; Isoenzymes; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 1998 |
Calcium-dependent nitric oxide synthase activity in rat thymocytes.
Topics: Animals; Arginine; Calcium; CD2 Antigens; Citrulline; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland | 1998 |
Effect of various agonists on nitric oxide generation by human polymorphonuclear leukocytes.
Topics: Concanavalin A; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1998 |
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.
Topics: Adrenergic beta-Agonists; Arginine; Cyclic GMP; Ethanolamines; Female; Heart; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1998 |
Effect of nitric oxide synthase inhibition on the sympatho-vagal contol of heart rate.
Topics: Adrenergic Fibers; Animals; Arginine; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Indazoles; Isoproterenol; Male; Neural Inhibition; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Polymethacrylic Acids; Propranolol; Rabbits; Sympatholytics; Sympathomimetics; Vagus Nerve | 1998 |
Nitric oxide synthesis by tracheal smooth muscle cells by a nitric oxide synthase-independent pathway.
Topics: Aminoquinolines; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxylamines; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxazines; Oximes; Rats; Rats, Inbred Lew; Trachea | 1998 |
Role of endogenous nitric oxide in ischaemia-reperfusion injury of rat gastric mucosa.
Topics: Animals; Chromium Radioisotopes; Edetic Acid; Enzyme Inhibitors; Fluorescence; Gastric Mucosa; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors | 1998 |
Effects of adrenergic and nitrergic blockade on theophylline-induced increase in peripheral blood flow in rat ear.
Topics: Acetylcholine; Adrenergic Agents; Animals; Atropine; Blood Pressure; Ear; Enzyme Inhibitors; Heart Rate; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Propranolol; Rats; Rats, Wistar; Regional Blood Flow; Reserpine; Theophylline | 1998 |
Non-enzymatic production of nitric oxide (NO) from NO synthase inhibitors.
Topics: Animals; Arginine; Mollusca; Nerve Tissue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine | 1998 |
Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 1. Acute treatments are active in the forced swim test.
Topics: Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swimming | 1999 |
Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus.
Topics: Action Potentials; Animals; Axons; Catalase; Electric Stimulation; Hippocampus; In Vitro Techniques; Myelin Basic Protein; Nerve Fibers, Myelinated; Neuroglia; Neurons; Nitroarginine; omega-N-Methylarginine; Phosphorylation; Protein Isoforms; Protein Kinase C; Pyramidal Cells; Pyramidal Tracts; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 1999 |
NO mediates postjunctional inhibitory effect of neurogenic ACh in guinea pig small intestinal microcirculation.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Female; Ganglia; Guinea Pigs; Intestine, Small; Iontophoresis; Male; Microcirculation; Nervous System; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pirenzepine; Vasoconstriction | 1999 |
Further attenuation of endothelium-dependent relaxation imparted by natriuretic peptide receptor antagonism.
Topics: Acetylcholine; Animals; Bradykinin; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Male; Natriuretic Peptide, C-Type; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Polysaccharides; Receptors, Atrial Natriuretic Factor; Vasodilation | 1999 |
Nitric oxide synthase expression and role during cardiomyogenesis.
Topics: Animals; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Gestational Age; Heart; Immunoblotting; Immunohistochemistry; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Nitrogen Oxides; omega-N-Methylarginine; Rats; Rats, Wistar; Signal Transduction; Spermine; Stem Cells | 1999 |
Nitric oxide production and mitochondrial dysfunction during rat thymocyte apoptosis.
Topics: Animals; Apoptosis; Cell Respiration; Cytochrome c Group; DNA Fragmentation; Etoposide; Flow Cytometry; Glutathione; Intracellular Membranes; Male; Methylprednisolone; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Thymus Gland | 2000 |
Effect of nitric oxide synthase inhibitors on lipid peroxide formation in liver caused by endotoxin challenge.
Topics: Animals; Antioxidants; Cell Count; Cell Line; Cell Survival; Endotoxins; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Lipid Peroxides; Lipopolysaccharides; Liver; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Sulfhydryl Compounds; Superoxides; Survival Rate | 2000 |
A microtiter-plate assay of human NOS isoforms.
Topics: Animals; Cell Line; Humans; Indicators and Reagents; Isoenzymes; Microchemistry; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; Spectrophotometry; Spodoptera; Transfection | 1998 |
Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings.
Topics: Animals; Aorta, Thoracic; Arginine; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Phenylephrine; Rats; Rats, Wistar | 1998 |
Central nervous system nitric oxide induces oropharyngeal swallowing and esophageal peristalsis in the cat.
Topics: Animals; Catheterization; Cats; Deglutition; Electric Stimulation; Enzyme Inhibitors; Esophagus; Female; Injections, Intravenous; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; omega-N-Methylarginine; Oropharynx; Peristalsis; Physical Stimulation; Water | 2000 |
Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum.
Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Cryptosporidiosis; Cryptosporidium parvum; Drug Synergism; Enterocytes; Enzyme Inhibitors; HT29 Cells; Humans; Interferon gamma Receptor; Interferon-gamma; Interleukin-1; Intestinal Mucosa; Iron; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Receptors, Interferon; Tryptophan; Tumor Necrosis Factor-alpha | 2001 |
NO supports right ventricular flow dominance and whole body O(2) utilization in midgestation fetal lambs.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Female; Fetal Blood; Fetus; Heart; Heart Rate; Hemodynamics; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen; Oxygen Consumption; Pregnancy; Sheep; Ventricular Function, Left; Ventricular Function, Right | 2001 |
The dual effect of a nitric oxide donor in nociception.
Topics: Animals; Chronic Disease; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemoglobins; Injections, Spinal; Ligation; Male; Molsidomine; Nerve Compression Syndromes; Neuralgia; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Sciatic Nerve | 2001 |
Relative significance of the nitric oxide (NO)/cGMP pathway and K+ channel activation in endothelium-dependent vasodilation in the femoral artery of developing piglets.
Topics: Acetylcholine; Animals; Animals, Newborn; Calcium Channel Blockers; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Male; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Potassium; Potassium Channels; Swine; Vasodilation; Vasodilator Agents | 2001 |
The interaction of nitric oxide and prostaglandins in the control of corporal smooth muscle tone: evidence for production of a cyclooxygenase-derived endothelium-contracting factor.
Topics: Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle, Smooth; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Penis; Prostaglandins; Rabbits | 2001 |
Re-evaluating NADPH-diaphorase histochemistry as an indicator of nitric oxide synthase: an examination of the olfactory system of coho salmon (Oncorhynchus kisutch).
Topics: Animals; Enzyme Inhibitors; NADPH Dehydrogenase; Nitric Oxide Synthase; Nitroarginine; Olfactory Pathways; omega-N-Methylarginine; Oncorhynchus kisutch | 2001 |
A triglyceride-rich fat emulsion and free fatty acids but not very low density lipoproteins impair endothelium-dependent vasorelaxation.
Topics: Acetylcholine; Animals; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Femoral Artery; In Vitro Techniques; Lipoproteins, VLDL; Male; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oleic Acid; omega-N-Methylarginine; Palmitic Acid; Penicillamine; Rats; Rats, Sprague-Dawley; Triglycerides; Vasodilation; Vasodilator Agents | 2001 |
Regulation of cyclooxygenase activity and progesterone production in the rat corpus luteum by inducible nitric oxide synthase.
Topics: Animals; Arachidonic Acid; Aspirin; Cells, Cultured; Corpus Luteum; Cyclooxygenase Inhibitors; Depression, Chemical; Enzyme Inhibitors; Female; Gonadotropins, Equine; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; omega-N-Methylarginine; Progesterone; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Rats, Inbred Strains | 2002 |
Two new nitric oxide synthase inhibitors: pyridoxal aminoguanidine and 8-quinolinecarboxylic hydrazide selectively inhibit basal but not agonist-stimulated release of nitric oxide in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Phenylephrine; Quinolines; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
[The effect of PGI2 on formation and development of hyperdynamic circulatory state in portal hypertensive rats].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; Hemodynamics; Hypertension, Portal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Random Allocation; Rats; Rats, Sprague-Dawley | 2003 |
Pharmacological manipulation of nitric oxide levels in mouse follicle cultures demonstrates key role of extrafollicular control of ovulation.
Topics: Animals; Enzyme Inhibitors; Female; Interleukin-1; Isothiuronium; Lipopolysaccharides; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Nitroso Compounds; omega-N-Methylarginine; Organ Culture Techniques; Ovarian Follicle; Ovulation; S-Nitroso-N-Acetylpenicillamine | 2004 |
The role of nitric oxide in the spatial heterogeneity of basal microvascular blood flow in the rat diaphragm.
Topics: Animals; Diaphragm; Enzyme Inhibitors; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2005 |
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Anguilla; Animals; Arginine; Bicarbonates; Chlorides; Cyclic GMP; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Potentials; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Permeability; Quinoxalines; Time Factors | 2007 |
Effects of nitric oxide synthase inhibitors in attenuating nicotine withdrawal in rats.
Topics: Animals; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mecamylamine; Motor Activity; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2008 |
Involvement of accumulated NOS inhibitors and endothelin-1, enhanced arginase, and impaired DDAH activities in pulmonary dysfunction following subarachnoid hemorrhage in the rabbit.
Topics: Acetylcholine; Amidohydrolases; Animals; Arginase; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Indomethacin; Lung Diseases; Male; Models, Biological; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Pulmonary Artery; Quinoxalines; Rabbits; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Vasoconstriction | 2008 |
Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization.
Topics: Animals; Cell Line; Enzyme Inhibitors; Guanidines; Lysine; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Protein Multimerization; Substrate Specificity | 2012 |
Inducible NOS mediates CNP-induced relaxation of intestinal myofibroblasts.
Topics: Animals; Cyclic GMP; Guanylate Cyclase; Humans; Mice; Muscle Relaxation; Myofibroblasts; Natriuretic Peptide, C-Type; Nitric Oxide Synthase Type II; Nitroarginine; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2013 |