Page last updated: 2024-09-03

omega-n-methylarginine and naloxone

omega-n-methylarginine has been researched along with naloxone in 6 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
4,41134433620,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cappendijk, SL; de Vries, R; Dzoljic, MR1
Deliconstantinos, G; Stavrides, JC; Villiotou, V1
Capasso, A; Carnuccio, R; D'Acquisto, F; Iuvone, T1
Dambisya, YM; Lee, TL1
Cunha, FQ; Duarte, DB; Ferrari, LF; Ferreira, SH; Funez, MI; Lorenzetti, BB; Parada, CA; Sachs, D1
Baamonde, A; González-Rodríguez, S; Hidalgo, A; Menéndez, L1

Other Studies

6 other study(ies) available for omega-n-methylarginine and naloxone

ArticleYear
Inhibitory effect of nitric oxide (NO) synthase inhibitors on naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
    Neuroscience letters, 1993, Nov-12, Volume: 162, Issue:1-2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Behavior, Animal; Diarrhea; Male; Mice; Morphine Dependence; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Substance Withdrawal Syndrome

1993
Met-enkephalin receptor-mediated increase of membrane fluidity modulates nitric oxide (NO) and cGMP production in rat brain synaptosomes.
    Neurochemical research, 1995, Volume: 20, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Cyclic GMP; Enkephalin, Methionine; Fluorescence Polarization; Kinetics; Membrane Fluidity; Naloxone; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Receptors, Opioid; Synaptosomes; Thermodynamics

1995
Opioids inhibit the induction of nitric oxide synthase in J774 macrophages.
    Biochemical and biophysical research communications, 1995, Jul-26, Volume: 212, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Induction; Lipopolysaccharides; Macrophages; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Pyrrolidines; Receptors, Opioid

1995
Role of nitric oxide in the induction and expression of morphine tolerance and dependence in mice.
    British journal of pharmacology, 1996, Volume: 117, Issue:5

    Topics: Animals; Arginine; Drug Interactions; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Substance Withdrawal Syndrome

1996
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-09, Volume: 105, Issue:49

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Dopamine; Drug Interactions; Enzyme Inhibitors; Indomethacin; Interleukin-1beta; Male; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Sensory Receptor Cells; Signal Transduction

2008
Spinal and peripheral mechanisms involved in the enhancement of morphine analgesia in acutely inflamed mice.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:1

    Topics: Acute Disease; Analgesia; Animals; Carrageenan; Glyburide; Inflammation; Injections, Spinal; Mice; Molsidomine; Morphine; Naloxone; Nociceptors; omega-N-Methylarginine; Pain; Quaternary Ammonium Compounds; Spinal Cord; Temperature

2010