Page last updated: 2024-09-03

omega-n-methylarginine and n-(3-(aminomethyl)benzyl)acetamidine

omega-n-methylarginine has been researched along with n-(3-(aminomethyl)benzyl)acetamidine in 12 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(n-(3-(aminomethyl)benzyl)acetamidine)
Trials
(n-(3-(aminomethyl)benzyl)acetamidine)
Recent Studies (post-2010) (n-(3-(aminomethyl)benzyl)acetamidine)
4,4113443363281106

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)n-(3-(aminomethyl)benzyl)acetamidine (IC50)
Nitric oxide synthase, brainHomo sapiens (human)4.89
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)7.55
Nitric oxide synthase, inducibleMus musculus (house mouse)0.177
Nitric oxide synthase, inducibleHomo sapiens (human)0.1395

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's9 (75.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB1
Hamilton, LC; Warner, TD1
Dugas, B; Dugas, N; Fourneau, JM; Kolb, JP; Marconi, A; Roman, V; Sigaux, F; Zhao, H1
Gilroy, DW; Paul-Clark, MJ; Tomlinson, A; Willis, D; Willoughby, DA1
Fermor, B; Fink, C; Guilak, F; LeGrand, A; Pisetsky, DS; Vail, TP; Weinberg, JB1
Grant, AL; Hagan, RM; Starkey, SJ1
Slomiany, A; Slomiany, BL1
Abe, K; Chiba, Y; Matsuo, K; Misawa, M; Sakai, H1
Mayr, FB; Spiel, AO1
Boer, R; Ghofrani, HA; Grimminger, F; Lehner, M; Maring, D; Mayer, K; Pullamsetti, SS; Rosengarten, B; Schermuly, RT; Schudt, C; Seeger, W; Weissmann, N1
Diesen, DL; Hess, DT; Stamler, JS1
Astiz, ME; Berna, G; Griffin, K; Khan, R; Kirschenbaum, LA; LaRow, C1

Other Studies

12 other study(ies) available for omega-n-methylarginine and n-(3-(aminomethyl)benzyl)acetamidine

ArticleYear
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats

1999
Interactions between inducible isoforms of nitric oxide synthase and cyclo-oxygenase in vivo: investigations using the selective inhibitors, 1400W and celecoxib.
    British journal of pharmacology, 1998, Volume: 125, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Amidines; Analysis of Variance; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylamines; Celecoxib; Crotonates; Cyclooxygenase 2; Dexamethasone; Diclofenac; Enzyme Inhibitors; Hydroxybutyrates; Isoenzymes; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitriles; Nitrites; Nitrogen Dioxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Toluidines

1998
Expression of a functional inducible nitric oxide synthase in hairy cell leukaemia and ESKOL cell line.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Amidines; Antibodies, Monoclonal; Apoptosis; Arginine; Benzylamines; Blotting, Western; Enzyme Induction; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Leukemic; Humans; Leukemia, Hairy Cell; Microscopy, Fluorescence; Neoplasm Proteins; Neoplastic Stem Cells; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2000
Nitric oxide synthase inhibitors have opposite effects on acute inflammation depending on their route of administration.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-15, Volume: 166, Issue:2

    Topics: Acute Disease; Amidines; Animals; Antioxidants; Benzylamines; Carrageenan; Disease Models, Animal; Drug Administration Schedule; Edema; Enzyme Inhibitors; Free Radical Scavengers; Inflammation; Inflammation Mediators; Injections; Injections, Intraperitoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pleura; Pleurisy; Rats; Rats, Wistar; Superoxides; Thiourea

2001
Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:9

    Topics: Aged; Amidines; Benzylamines; Cell Survival; Cells, Cultured; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Humans; Interleukin-1; Interleukin-17; Menisci, Tibial; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitrobenzenes; omega-N-Methylarginine; Osteoarthritis, Knee; Sulfonamides; Tumor Necrosis Factor-alpha

2001
A rapid and transient synthesis of nitric oxide (NO) by a constitutively expressed type II NO synthase in the guinea-pig suprachiasmatic nucleus.
    British journal of pharmacology, 2001, Volume: 134, Issue:5

    Topics: Amidines; Animals; Benzylamines; Calcium; Dose-Response Relationship, Drug; Electrochemistry; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guinea Pigs; In Vitro Techniques; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suprachiasmatic Nucleus; Tissue Distribution

2001
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 1

    Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin

2004
Effects of 1400W, a potent selective inducible NOS inhibitor, on histamine- and leukotriene D4-induced relaxation of isolated guinea pig nasal mucosa.
    Nitric oxide : biology and chemistry, 2006, Volume: 15, Issue:2

    Topics: Amidines; Animals; Benzylamines; Enzyme Inhibitors; Guinea Pigs; Histamine; Leukotriene D4; Nasal Mucosa; Nitric Acid; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Vasodilation

2006
NO-synthase inhibition in sepsis.
    Thrombosis and haemostasis, 2006, Volume: 95, Issue:4

    Topics: Amidines; Animals; Benzylamines; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Sepsis; Shock, Septic

2006
Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock.
    Thrombosis and haemostasis, 2006, Volume: 95, Issue:4

    Topics: Amidines; Animals; Benzylamines; Disease Models, Animal; Enzyme Inhibitors; Epinephrine; Hemoglobins; Male; Microcirculation; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Shock, Septic

2006
Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal.
    Circulation research, 2008, Aug-29, Volume: 103, Issue:5

    Topics: Amidines; Animals; Aorta; Benzylamines; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Hemoglobins; Humans; Hypoxia; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitrogen; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Regional Blood Flow; Signal Transduction; Vasoconstriction; Vasodilation

2008
Augmentation of platelet and endothelial cell eNOS activity decreases sepsis-related neutrophil-endothelial cell interactions.
    Shock (Augusta, Ga.), 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Arginine; Endothelial Cells; Humans; Imines; Middle Aged; Neutrophils; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Shock, Septic

2010