Page last updated: 2024-09-03

omega-n-methylarginine and n(g),n(g')-dimethyl-l-arginine

omega-n-methylarginine has been researched along with n(g),n(g')-dimethyl-l-arginine in 71 studies

Compound Research Comparison

Studies (omega-n-methylarginine)	Trials (omega-n-methylarginine)	Recent Studies (post-2010) (omega-n-methylarginine)	Studies (n(g),n(g')-dimethyl-l-arginine)	Trials (n(g),n(g')-dimethyl-l-arginine)	Recent Studies (post-2010) (n(g),n(g')-dimethyl-l-arginine)
4,411	344	336	2,203	228	1,213

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (26.76)	18.2507
2000's	23 (32.39)	29.6817
2010's	24 (33.80)	24.3611
2020's	5 (7.04)	2.80

Authors

Authors	Studies
Lazarides, E; Lin, JM; Wang, C	1
Calver, A; Collier, J; Leone, A; Moncada, S; Vallance, P	1
Kakimoto, Y; Kondoh, K; Kotani, K; Sano, A; Ueno, S	1
Kakimoto, Y; Kotani, K; Sano, A; Ueno, S	1
MacAllister, RJ; Vallance, P; Whitley, GS	1
Fickling, SA; MacAllister, RJ; Vallance, P; Whitley, GS	1
Bennett, T; Gardiner, SM; Kemp, PA; Moncada, S; Palmer, RM	1
Hecker, M; Meyer, J; Richter, N	1
Azuma, H; Hamasaki, H; Isotani, E; Masuda, H; Obayashi, S; Sato, J; Tamaoki, S; Udagawa, T	1
Azuma, H; Masuda, H; Niwa, K; Sato, J; Tokoro, T	1
Dillon, MJ; Frend, A; Goonasekera, CD; Rees, DD; Shah, V; Woolard, P	1
Anderstam, B; Bergström, J; Katzarski, K	1
Bremer, V; Kimoto, M; Kimura, K; Ogawa, T; Omata, M; Tojo, A; Vallance, P; Welch, WJ; Wilcox, CS	1
Barnes, PJ; Cole, PJ; Dowling, RB; Newton, R; Robichaud, A; Wilson, R	1
Azuma, H; Goto, M; Masuda, H; Tamaoki, S	1
Cartwright, JE; Holden, DP; Whitley, GS	1
Aldasoro, M; Ballester, RM; Lluch, P; Lluch, S; Medina, P; Pelligrino, DA; Segarra, G; Vila, JM	1
Azuma, H	1
Leiper, J; Vallance, P	2
Bode-Böger, SM; Böger, RH; Frölich, JC; Sandmann, J; Tsikas, D	1
Aswad, DW; Bunick, GJ; Chen, D; Hanson, BL; Harp, JM; Henschen-Edman, A; Koh, SS; Mackay, DR; Schurter, BT; Stallcup, MR	1
Aso, T; Azuma, H; Beppu, M; Goto, M; Obayashi, S	1
Azuma, H; Masuda, H	1
Azuma, H; Goto, M; Kihara, K; Masuda, H; Okuno, T; Tsujii, T	1
Cardounel, AJ; Zweier, JL	1
Azuma, H; Kihara, K; Kurosaki, E; Masuda, H; Sakai, Y; Yamauchi, Y	1
Hayashida, Y; Morishita, T; Nakashima, Y; Nakata, S; Sasaguri, Y; Suda, O; Tasaki, H; Toyohira, Y; Tsujimoto, T; Tsutsui, M; Ueno, S; Ueta, Y; Yanagihara, N	1
Augustyniak, RA; Thomas, GD; Victor, RG; Zhang, W	1
Adegoke, OA; Chevalier, S; Gougeon, R; Lamarche, M; Marliss, EB; Morais, JA; Wu, G	1
Anthony, S; Leiper, J; Vallance, P	1
Schwedhelm, E	1
Dweik, RA	1
Berka, V; Cardounel, AJ; Cui, H; Johnson, W; Kearns, P; Samouilov, A; Tsai, AL; Zweier, JL	1
Barbara, JA; Hewitson, CL; Mangoni, AA; McAteer-Carr, B; Whiting, MJ; Woodman, RJ	1
Cardounel, AJ; Chen, CA; Druhan, LJ; Forbes, SP; Pope, AJ; Zweier, JL	1
Carru, C; Deiana, L; Scanu, B; Sotgia, S; Zinellu, A	1
Azuma, H; Hirata, Y; Imamura, M; Sakurada, M; Shichiri, M	1
Bralley, JA; Chirinos, JA; Chirinos-Pacheco, J; Corrales-Medina, F; Cuba-Bustinza, C; David, R; Medina-Lezama, J; Muñoz-Atahualpa, E; Zea-Díaz, H	1
Lianos, EA; McCarthy, ET; Miura, H; Papapetropoulos, A; Savin, VJ; Sharma, M; Sharma, R; Zhou, Z	1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z	1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z	1
Al-Zobaidy, MJ; Craig, J; Martin, W	1
Jung, CS	1
Atzler, D; Bache, RJ; Böger, RH; Chen, Y; Fassett, J; Guo, H; Hu, X; Lu, Z; Schwedhelm, E; Xu, X; Zhang, P	1
Cooke, JP; Ghebremariam, YT	1
Al-Zobaidy, MJ; Brown, K; Craig, J; Martin, W; Pettifor, G	1
Barbosa, JB; Brunini, TM; Mann, GE; Matsuura, C; Mendes-Ribeiro, AC; Moraes, TL; Moss, MB; Neto, ML; Siqueira, MA	1
Caplin, B; Leiper, J	1
Linz, TH; Lunte, SM	1
Bode-Böger, SM; Bódis, J; Hantosi, E; Kovács, GL; Martens-Lobenhoffer, J; Molnár, G; Sulyok, E; Tamás, P	1
Chen, B; Chicoine, LG; Cui, H; Jin, Y; Nelin, LD; Strauch, K	1
Akiyama, K; Fujii, K; Furuchi, T; Homma, H; Katane, M; Nonaka, S; Ozeki, Y; Saitoh, Y; Sekine, M; Shimoda, K; Tsunoda, M	1
Al-Zobaidy, MJ; Martin, W	1
Appelbaum, S; Atzler, D; Bauer, C; Blankenberg, S; Böger, RH; Hoffmann, B; Lackner, KJ; Münzel, T; Ojeda, FM; Ramuschkat, M; Schnabel, RB; Schwedhelm, E; Sinning, CR; Wild, PS; Zeller, T	1
Cherkanova, MS; Gilinsky, MA; Sukhovershin, RA	1
Bazer, FW; Che, D; Hou, Y; Hu, S; Jia, S; Nawaratna, G; Wang, F; Wu, G	1
Chen, A; Chen, Y; Fassett, JT; Hou, L; Liu, X; Xu, D; Xu, Y; Yang, L; Zhuang, Y	1
Akiyama, K; Fujii, K; Homma, H; Katane, M; Miyamoto, T; Nonaka-Hashida, S; Ozeki, Y; Saitoh, Y; Sekine, M; Shimoda, K; Tsunoda, M	1
Bailey, FJ; Lundgren, BR; Moley, G; Nomura, CT	1
Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E	1
Jiao, PL; Li, JK; Liu, B; Sun, JC; Tan, X; Wang, WZ; Wang, YK; Wu, ZT	1
Bode-Böger, SM; Emrich, IE; Fliser, D; Heine, GH; Martens-Lobenhoffer, J; Wagenpfeil, S; Zawada, AM	1
Chen, Y; Liu, X; Shang, R; Xu, X	1
Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E	1
Abusoglu, G; Abusoglu, S; Avci, A; Demir, K; Eryavuz, D; Hosaf, M; Unlu, A	1
Driver, T; Edelson-Averbukh, M; Katsanovskaja, K; Pipkorn, R	1
Gao, Y; Huang, H; Huang, M; Lv, W; Tang, H; Xiao, H	1
Berent, TE; Dorschner, JM; Jatoi, A; Kumar, R; Kunz, HE; Lanza, IR; Meyer, T; Wang, X	1
Alptekin, H; Karaman, S; Onmaz, DE; Sivrikaya, A	1
Doğan, Ö; Haşimi, A; Serdar, CC; Serdar, MA	1

Reviews

10 review(s) available for omega-n-methylarginine and n(g),n(g')-dimethyl-l-arginine

Article	Year
Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. Cardiovascular research, 1999, Aug-15, Volume: 43, Issue:3 Topics: Amidohydrolases; Animals; Arginine; Cytosol; Enzyme Inhibitors; Humans; Hydrolases; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases	1999
[Biological and pathophysiological roles of endogenous methylarginines as inhibitors of nitric oxide synthase]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2002, Volume: 119, Issue:1 Topics: Animals; Arginine; Nitric Oxide Synthase; omega-N-Methylarginine	2002
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:6 Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Diabetes Mellitus; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Mice; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pre-Eclampsia; Pregnancy; Protein-Arginine N-Methyltransferases; Renal Insufficiency	2004
Nitric oxide pathway as new drug targets for refractory hypertension. Current pharmaceutical design, 2005, Volume: 11, Issue:25 Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Endothelium, Vascular; Humans; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Signal Transduction; Superoxides	2005
Endogenous production of nitric oxide synthase inhibitors. Vascular medicine (London, England), 2005, Volume: 10 Suppl 1 Topics: Arginine; Enzyme Inhibitors; Humans; Isoenzymes; Nitric Oxide Synthase; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Renal Insufficiency	2005
Quantification of ADMA: analytical approaches. Vascular medicine (London, England), 2005, Volume: 10 Suppl 1 Topics: Arginine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; omega-N-Methylarginine; Reproducibility of Results	2005
The lung in the balance: arginine, methylated arginines, and nitric oxide. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:1 Topics: Animals; Arginine; Humans; Lung; Methylation; Models, Biological; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases	2007
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators? Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6 Topics: Amidohydrolases; Animals; Arginine; Binding Sites; Binding, Competitive; Biomarkers; Cardiovascular Agents; Cardiovascular Diseases; Catalytic Domain; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine	2012
Effect of asymmetric dimethylarginine (ADMA) on heart failure development. Nitric oxide : biology and chemistry, 2016, Apr-01, Volume: 54 Topics: Amidohydrolases; Animals; Arginine; Heart Failure; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Signal Transduction; Superoxides	2016
Asymmetric dimethylarginine (ADMA) as an important risk factor for the increased cardiovascular diseases and heart failure in chronic kidney disease. Nitric oxide : biology and chemistry, 2018, 08-01, Volume: 78 Topics: Amidohydrolases; Animals; Arginine; Endothelium, Vascular; Heart Failure; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Renal Insufficiency, Chronic; Risk Factors; Signal Transduction	2018

Trials

1 trial(s) available for omega-n-methylarginine and n(g),n(g')-dimethyl-l-arginine

Article	Year
Effects of some guanidino compounds on human cerebral arteries. Stroke, 1999, Volume: 30, Issue:10 Topics: Adult; Aged; Arginine; Enzyme Inhibitors; Female; Guanidines; Humans; Male; Methylguanidine; Middle Aged; Middle Cerebral Artery; Nitric Oxide Synthase; omega-N-Methylarginine; Vasoconstrictor Agents; Vasodilator Agents	1999

Other Studies

60 other study(ies) available for omega-n-methylarginine and n(g),n(g')-dimethyl-l-arginine

Article	Year
Methylations of 70,000-Da heat shock proteins in 3T3 cells: alterations by arsenite treatment, by different stages of growth and by virus transformation. Archives of biochemistry and biophysics, 1992, Aug-15, Volume: 297, Issue:1 Topics: 3T3 Cells; Animals; Arginine; Arsenic; Arsenites; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Viral; Chromatography, Ion Exchange; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; Lysine; Methionine; Methylation; Mice; Molecular Weight; omega-N-Methylarginine	1992
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet (London, England), 1992, Mar-07, Volume: 339, Issue:8793 Topics: Adult; Animals; Aorta; Arginine; Blood Pressure; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Forearm; Guinea Pigs; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Rats; Reference Values; Regional Blood Flow	1992
Distribution of free methylarginines in rat tissues and in the bovine brain. Journal of neurochemistry, 1992, Volume: 59, Issue:6 Topics: Animals; Arginine; Brain Chemistry; Cattle; Intestines; Male; Myocardium; omega-N-Methylarginine; Rats; Rats, Wistar; Spleen; Testis; Tissue Distribution	1992
Isolation and identification of methylarginines from bovine brain. Journal of neurochemistry, 1992, Volume: 58, Issue:3 Topics: Animals; Arginine; Brain; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Paper; omega-N-Methylarginine	1992
Effects of guanidino and uremic compounds on nitric oxide pathways. Kidney international, 1994, Volume: 45, Issue:3 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanidines; Humans; Macrophages; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein	1994
Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Amino Acid Oxidoreductases; Arginase; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Endothelium, Vascular; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Umbilical Veins	1994
Regional and cardiac haemodynamic effects of NG, NG,dimethyl-L-arginine and their reversibility by vasodilators in conscious rats. British journal of pharmacology, 1993, Volume: 110, Issue:4 Topics: Animals; Arginine; Glutathione; Hemodynamics; Hydralazine; Male; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Vasodilator Agents	1993
High-performance liquid chromatographic determination of nitric oxide synthase-related arginine derivatives in vitro and in vivo. Analytical biochemistry, 1997, Apr-05, Volume: 247, Issue:1 Topics: Animals; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Female; Humans; In Vitro Techniques; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reference Values; Reproducibility of Results; Sensitivity and Specificity	1997
Effect of nicotine on the intimal hyperplasia after endothelial removal of the rabbit carotid artery. General pharmacology, 1997, Volume: 28, Issue:5 Topics: Animals; Arginine; Body Weight; Carotid Arteries; Endothelin-1; Endothelium, Vascular; Hyperplasia; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Tunica Intima	1997
A possible role of endogenous inhibitor for nitric oxide synthesis in the bovine ciliary muscle. Experimental eye research, 1997, Volume: 64, Issue:5 Topics: Animals; Arginine; Calcimycin; Cattle; Ciliary Body; Ionophores; Muscle Relaxation; Nitric Oxide; Nitroprusside; omega-N-Methylarginine	1997
Nitric oxide synthase inhibitors and hypertension in children and adolescents. Journal of hypertension, 1997, Volume: 15, Issue:8 Topics: Adolescent; Animals; Arginine; Child; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; In Vitro Techniques; Male; Mice; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Renin; Vasoconstrictor Agents	1997
Serum levels of NG, NG-dimethyl-L-arginine, a potential endogenous nitric oxide inhibitor in dialysis patients. Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:9 Topics: Arginine; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Nitric Oxide; omega-N-Methylarginine; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis	1997
Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney. Kidney international, 1997, Volume: 52, Issue:6 Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Enzyme Inhibitors; Hydrolases; Kidney Glomerulus; Loop of Henle; Male; Methylation; Microscopy, Immunoelectron; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Tritium	1997
Effect of inhibition of nitric oxide synthase on Pseudomonas aeruginosa infection of respiratory mucosa in vitro. American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:6 Topics: Arginine; Bacterial Adhesion; Enzyme Inhibitors; Gene Expression; Humans; Microscopy, Electron, Scanning; Mucous Membrane; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Organ Culture Techniques; Pseudomonas aeruginosa; Respiratory System; RNA, Messenger	1998
Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. British journal of pharmacology, 1999, Volume: 126, Issue:1 Topics: Alloxan; Animals; Arginine; Blood Glucose; Body Weight; Carotid Arteries; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hyperglycemia; Hyperplasia; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Rabbits; Tunica Intima; Tunica Media; Weight Gain	1999
Hepatocyte growth factor regulates human trophoblast motility and invasion: a role for nitric oxide. British journal of pharmacology, 1999, Volume: 128, Issue:1 Topics: Arginine; Cell Division; Cell Line; Cell Movement; Cell Size; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Induction; Female; Fibrin; Hepatocyte Growth Factor; Humans; Integrins; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; RNA, Messenger; Transfection; Trophoblasts; Tumor Necrosis Factor-alpha	1999
[Role of L-arginine--endogenous NOS inhibitors--endothelin-1 pathway for the vascular remodelling]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114 Suppl 1 Topics: Animals; Arginine; Carotid Arteries; Cell Division; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Regeneration	1999
Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox. FEBS letters, 2000, Jul-28, Volume: 478, Issue:1-2 Topics: Animals; Arginine; Binding, Competitive; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Meta-Analysis as Topic; Models, Biological; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thermodynamics	2000
Methylation of histone H3 by coactivator-associated arginine methyltransferase 1. Biochemistry, 2001, May-15, Volume: 40, Issue:19 Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Catalysis; Cattle; Chickens; Chromatography, High Pressure Liquid; Enzyme Activation; Histones; Kinetics; Methylation; Molecular Sequence Data; Oligopeptides; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity	2001
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2 Topics: Adult; Arginine; Arteries; Chromatography, High Pressure Liquid; Climacteric; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperplasia; In Vitro Techniques; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tunica Intima; Tunica Media; Uterus	2002
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:6 Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; Impotence, Vasculogenic; In Vitro Techniques; Ischemia; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits; Vasoconstrictor Agents; Vasodilator Agents	2002
Endogenous methylarginines regulate neuronal nitric-oxide synthase and prevent excitotoxic injury. The Journal of biological chemistry, 2002, Sep-13, Volume: 277, Issue:37 Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Rats	2002
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit. The Journal of urology, 2004, Volume: 172, Issue:1 Topics: Aging; Animals; Arginase; Arginine; Carbachol; Cholinergic Agonists; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits	2004
Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:9 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Coronary Disease; Enzyme Induction; Homocysteine; Imidazoles; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Olmesartan Medoxomil; omega-N-Methylarginine; Oxidative Stress; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Superoxides; Tetrazoles; Thiazepines	2004
Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover. Diabetologia, 2006, Volume: 49, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Blood Glucose; Body Composition; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Obesity; omega-N-Methylarginine; Proteins; Regression Analysis; Sex Characteristics	2006
Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function. The Journal of biological chemistry, 2007, Jan-12, Volume: 282, Issue:2 Topics: Animals; Aorta; Arginine; Carotid Artery Injuries; Catheterization; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Male; Methylation; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Rats, Wistar; Vasodilation	2007
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension. American journal of hypertension, 2008, Volume: 21, Issue:8 Topics: Aged; Arginine; Biomarkers; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; omega-N-Methylarginine; Predictive Value of Tests; Renal Dialysis	2008
Regulation of eNOS-derived superoxide by endogenous methylarginines. Biochemistry, 2008, Jul-08, Volume: 47, Issue:27 Topics: Arginine; Biopterins; Electron Spin Resonance Spectroscopy; Heme; Humans; NADP; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Superoxides	2008
Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation. Clinical biochemistry, 2008, Volume: 41, Issue:14-15 Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Health; Humans; Male; Methylation; Middle Aged; omega-N-Methylarginine; Proteins; Reference Values; Regression Analysis	2008
Nitric oxide upregulates dimethylarginine dimethylaminohydrolase-2 via cyclic GMP induction in endothelial cells. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:5 Topics: Amidohydrolases; Animals; Arginine; Carbazoles; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Male; Natriuretic Peptide, C-Type; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitro Compounds; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Up-Regulation	2008
Endogenous nitric oxide synthase inhibitors, arterial hemodynamics, and subclinical vascular disease: the PREVENCION Study. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:6 Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Blood Flow Velocity; Blood Pressure; Carotid Artery Diseases; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Predictive Value of Tests; Prognosis; Pulsatile Flow; Regression Analysis; Risk Factors	2008
ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide. American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:6 Topics: Albumins; Animals; Anthracenes; Arginine; Free Radical Scavengers; Glomerular Basement Membrane; Guanylate Cyclase; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Permeability; Propane; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Superoxides	2009
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death. British journal of haematology, 2009, Volume: 145, Issue:4 Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate	2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9 Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors	2009
Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine in the rat aorta. British journal of pharmacology, 2010, Volume: 160, Issue:6 Topics: Acetylcholine; Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar	2010
Nitric oxide synthase inhibitors and cerebral vasospasm. Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 1 Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; S-Adenosylmethionine; Vasospasm, Intracranial	2011
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:7 Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Female; Genotype; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, 129 Strain; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenotype; Risk Factors; RNA Interference; Substrate Specificity; Time Factors; Transfection	2011
DDAH says NO to ADMA. Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:7 Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Risk Factors; Substrate Specificity	2011
Stimulus-specific blockade of nitric oxide-mediated dilatation by asymmetric dimethylarginine (ADMA) and monomethylarginine (L-NMMA) in rat aorta and carotid artery. European journal of pharmacology, 2011, Dec-30, Volume: 673, Issue:1-3 Topics: Animals; Aorta; Arginine; Carotid Arteries; Female; Male; Naphthyridines; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pyrimidines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation	2011
Nitric oxide activity in platelets of dengue haemorrhagic fever patients: the apparent paradoxical role of ADMA and l-NMMA. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012, Volume: 106, Issue:3 Topics: Adult; Arginine; Blood Platelets; Brazil; Enzyme Inhibitors; Female; Humans; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Severe Dengue; Thrombocytopenia	2012
Heat-assisted extraction for the determination of methylarginines in serum by CE. Electrophoresis, 2013, Volume: 34, Issue:11 Topics: Arginine; Cardiovascular Diseases; Electrophoresis, Capillary; Hot Temperature; Humans; omega-N-Methylarginine; Solid Phase Extraction	2013
L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies. Scandinavian journal of clinical and laboratory investigation, 2013, Volume: 73, Issue:5 Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Fetal Blood; Humans; omega-N-Methylarginine; Ornithine; Pre-Eclampsia; Pregnancy; Young Adult	2013
Asymmetric dimethylarginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells. Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:7 Topics: Animals; Arginase; Arginine; Cattle; Cell Proliferation; Endothelial Cells; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Substrate Specificity; Urea	2014
Simultaneous determination of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L-arginine, N(G),N(G')-dimethyl-L-arginine, and L-arginine using monolithic silica disk-packed spin columns and a monolithic silica column. Journal of separation science, 2014, Volume: 37, Issue:16 Topics: Arginine; Calibration; Chromatography, High Pressure Liquid; Fluorescent Dyes; Healthy Volunteers; Humans; Linear Models; omega-N-Methylarginine; Reproducibility of Results; Silicon Dioxide; Solid Phase Extraction	2014
The ability of asymmetric dimethylarginine (ADMA) or monomethylarginine (L-NMMA) to block endothelium-dependent, nitric oxide-mediated relaxation in rat aorta is inversely related to the efficacy of the relaxant stimulus. European journal of pharmacology, 2014, Oct-15, Volume: 741 Topics: Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Vasodilation	2014
ADMA, subclinical changes and atrial fibrillation in the general population. International journal of cardiology, 2016, Jan-15, Volume: 203 Topics: Adult; Aged; Arginine; Atrial Fibrillation; Biomarkers; Chromatography, Liquid; Echocardiography; Electrocardiography; Female; Germany; Humans; Male; Middle Aged; Morbidity; omega-N-Methylarginine; Oxidative Stress; Population Surveillance; Tandem Mass Spectrometry	2016
Methylarginines in Mice with Experimental Atherosclerosis. Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1 Topics: Animals; Arginine; Atherosclerosis; Cholesterol; Endothelium, Vascular; Male; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; omega-N-Methylarginine; Poloxamer; Triglycerides	2015
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine. Amino acids, 2016, Volume: 48, Issue:4 Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; Homoarginine; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Swine; Zea mays	2016
Plasma concentrations of three methylated arginines, endogenous nitric oxide synthase inhibitors, in schizophrenic patients undergoing antipsychotic drug treatment. Psychiatry research, 2016, Apr-30, Volume: 238 Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arginine; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Schizophrenia; Treatment Outcome; Young Adult	2016
DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1. Journal of bacteriology, 2017, 04-15, Volume: 199, Issue:8 Topics: Amidohydrolases; Arginine; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; omega-N-Methylarginine; Pseudomonas aeruginosa; RNA Polymerase Sigma 54	2017
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study. The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6 Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry	2017
The asymmetric dimethylarginine-mediated inhibition of nitric oxide in the rostral ventrolateral medulla contributes to regulation of blood pressure in hypertensive rats. Nitric oxide : biology and chemistry, 2017, Jul-01, Volume: 67 Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Heart Rate; Kidney; Losartan; Male; Medulla Oblongata; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Rats, Inbred WKY; Rats, Sprague-Dawley; Sympathetic Nervous System	2017
Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease. Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:3 Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, Liquid; Disease Progression; Female; Germany; Humans; Incidence; Male; Middle Aged; omega-N-Methylarginine; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors	2018
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial. Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:2 Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors	2019
Total methylated arginine load as a risk parameter in subjects with masked hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Volume: 42, Issue:2 Topics: Arginine; Biomarkers; Blood Pressure Determination; Female; Humans; Hypertension; Male; Masked Hypertension; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Risk Factors	2020
Negative Ion Mode Collision-Induced Dissociation for Analysis of Protein Arginine Methylation. Journal of the American Society for Mass Spectrometry, 2019, Volume: 30, Issue:7 Topics: Amino Acid Sequence; Arginine; omega-N-Methylarginine; Peptides; Protein Processing, Post-Translational; Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2019
The Role of Reactive Oxygen Species and Nitric Oxide in the Inhibition of Oxidative medicine and cellular longevity, 2020, Volume: 2020 Topics: Arginine; Catecholamines; Cell Line; Enzyme Inhibitors; Humans; Imidazolines; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peptide Hydrolases; Reactive Oxygen Species; Trichophyton	2020
Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting. The Journal of biological chemistry, 2020, 12-18, Volume: 295, Issue:51 Topics: Animals; Arginine; Cachexia; Female; Heterografts; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle Proteins; Neoplasms; omega-N-Methylarginine	2020
Altered methylarginine levels after surgery in subjects with multinodular goiter. Hormone molecular biology and clinical investigation, 2021, Feb-22, Volume: 42, Issue:3 Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Goiter, Nodular; Humans; Male; Middle Aged; omega-N-Methylarginine; Postoperative Period; Sensitivity and Specificity	2021
Association of serum ADMA, SDMA and L-NMMA concentrations with disease progression in COVID-19 patients. Biochemia medica, 2023, Feb-15, Volume: 33, Issue:1 Topics: Arginine; COVID-19; Disease Progression; Humans; omega-N-Methylarginine	2023