Page last updated: 2024-09-03

omega-n-methylarginine and methacholine chloride

omega-n-methylarginine has been researched along with methacholine chloride in 23 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(methacholine chloride)
Trials
(methacholine chloride)
Recent Studies (post-2010) (methacholine chloride)
4,4113443365,443835824

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)methacholine chloride (IC50)
galanin receptor type 3Homo sapiens (human)7.365

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (60.87)18.2507
2000's9 (39.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, PJ; Pearson, PJ; Schaff, HV1
Rongen, GA; Smits, P; Thien, T1
Bauer, MB; Gebhart, GF; Murphy, S1
Fedan, JS; Frazer, DG; Robinson, Va; Warner, TE; Yuan, LX1
Chowienczyk, PJ; Cockcroft, JR; Ritter, JM1
Anand, IS; Chandrashekhar, Y; Chawla, LS; Wander, GS1
Baron, AD; Brechtel, G; Fineberg, N; Johnson, A; Steinberg, HO1
Bellofiore, S; Di Maria, GU; Geppetti, P; Mistretta, A; Nadel, JA; Ricciardolo, FL; Sapienza, MA1
Buikema, H; Grandjean, JG; Pinto, YM; Rooks, G; Schunkert, H; van Gilst, WH1
Cohn, JN; Lemay, L; McVeigh, GE; Morgan, D1
Boles, K; Creager, MA; Roddy, MA; Stamler, JS1
Aoki, T; Fukuchi, Y; Kurihara, H; Kurihara, Y; Nagase, T; Ouchi, Y; Yazaki, Y1
Chipkin, SR; Coffman, JD; Cohen, RA; Khan, F; Ruderman, NB1
Homma, T; Irvin, CG1
Baron, AD; Cronin, J; Crowde, K; Hempfling, A; Hook, G; Paradisi, G; Steinberg, HO1
Holt, PG; Sly, PD; Tulić, MK; Wale, JL1
Davidge, ST; Stewart, KG; Zhang, Y1
Biegelsen, ES; Duffy, SJ; Gokce, N; Holbrook, M; Keaney, JF; Russell, JD; Vita, JA1
Cook, JL; Davidge, ST; Zhang, Y1
López-Dóriga, P; Neira, M; Pavón, I; Peiró, C; Petidier, R; Rodríguez-Mañas, L; Sánchez-Ferrer, CF; Solís, J1
Coffman, JD; Duffy, SJ; Eberhardt, RT; Loscalzo, J; McMahon, L; Perrine, SP; Steinberg, MH; Vita, JA1
Huang, T; Lombard, JH; Mori, T; Zhu, J1
Lee, K; Mack, GW1

Trials

5 trial(s) available for omega-n-methylarginine and methacholine chloride

ArticleYear
Inhibition of acetylcholinesterase selectively potentiates NG-monomethyl-L-arginine-resistant actions of acetylcholine in human forearm vasculature.
    Clinical science (London, England : 1979), 1995, Volume: 88, Issue:1

    Topics: Acetylcholine; Adult; Arginine; Dose-Response Relationship, Drug; Drug Synergism; Edrophonium; Forearm; Humans; Kinetics; Methacholine Chloride; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation

1995
Endothelium-derived relaxing factor is important in mediating the high output state in chronic severe anemia.
    Journal of the American College of Cardiology, 1995, Volume: 25, Issue:6

    Topics: Adult; Anemia; Arginine; Cardiac Output, High; Chronic Disease; Dose-Response Relationship, Drug; Forearm; Hemodynamics; Humans; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Single-Blind Method; Vascular Resistance

1995
Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma.
    Lancet (London, England), 1996, Aug-10, Volume: 348, Issue:9024

    Topics: Adult; Aerosols; Arginine; Asthma; Bradykinin; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine

1996
Iron chelation improves endothelial function in patients with coronary artery disease.
    Circulation, 2001, Jun-12, Volume: 103, Issue:23

    Topics: Adult; Blood Flow Velocity; Coronary Disease; Deferoxamine; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Free Radical Scavengers; Humans; Infusions, Intra-Arterial; Iron; Iron Chelating Agents; Male; Methacholine Chloride; Middle Aged; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Vasodilation; Vasomotor System

2001
Effect of glycaemic control on the vascular nitric oxide system in patients with type 1 diabetes.
    Journal of hypertension, 2003, Volume: 21, Issue:6

    Topics: Adult; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Female; Humans; Hyperglycemia; Male; Methacholine Chloride; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Oxidative Stress; Parasympathomimetics; Plethysmography; Regional Blood Flow; Superoxide Dismutase; Superoxides; Vasodilation; Vasodilator Agents

2003

Other Studies

18 other study(ies) available for omega-n-methylarginine and methacholine chloride

ArticleYear
Endothelium-dependent contraction and relaxation of the human and canine internal mammary artery: studies on bypass graft vasospasm.
    Surgery, 1991, Volume: 110, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Dogs; Endothelins; Female; Humans; Hypoxia; In Vitro Techniques; Male; Mammary Arteries; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine

1991
NG-monomethyl-L-ARG reduces the forearm vasodilator response to acetylcholine but not to methacholine in humans.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:6

    Topics: Acetylcholine; Adolescent; Adult; Arginine; Blood Pressure; Forearm; Humans; Infusions, Intravenous; Male; Methacholine Chloride; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Vasodilation

1993
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
    Neuroscience, 1994, Volume: 62, Issue:2

    Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction

1994
Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Airway Resistance; Amino Acid Oxidoreductases; Animals; Arginine; Epithelium; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Male; Methacholine Chloride; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Penicillamine; Respiration; S-Nitroso-N-Acetylpenicillamine; Trachea

1995
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Adult; Analysis of Variance; Arginine; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Infusions, Intra-Arterial; Insulin; Male; Methacholine Chloride; Muscles; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Time Factors; Vascular Resistance; Vasodilation

1994
The deletion polymorphism of the angiotensin-converting enzyme gene is related to phenotypic differences in human arteries.
    European heart journal, 1996, Volume: 17, Issue:5

    Topics: Angiotensins; Arteries; Endothelium, Vascular; Female; Gene Deletion; Genes; Humans; In Vitro Techniques; Male; Mammary Arteries; Methacholine Chloride; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Peptidyl-Dipeptidase A; Phenotype; Phenylephrine; Polymorphism, Genetic; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

1996
Effects of long-term cigarette smoking on endothelium-dependent responses in humans.
    The American journal of cardiology, 1996, Sep-15, Volume: 78, Issue:6

    Topics: Adult; Brachial Artery; Carboxyhemoglobin; Endothelium, Vascular; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Plethysmography; Smoking; Time Factors; Vascular Resistance; Vasodilator Agents

1996
N-acetylcysteine does not influence the activity of endothelium-derived relaxing factor in vivo.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:2

    Topics: Acetylcysteine; Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Humans; Injections, Intra-Arterial; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine

1997
Airway hyperresponsiveness to methacholine in mutant mice deficient in endothelin-1.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:2

    Topics: Airway Resistance; Animals; Endothelin-1; Enzyme Inhibitors; Lung; Methacholine Chloride; Mice; Mice, Knockout; Nitric Oxide Synthase; omega-N-Methylarginine; Ovalbumin; Respiratory Hypersensitivity; Serotonin

1998
Vasodilator responses in the forearm skin of patients with insulin-dependent diabetes mellitus.
    Vascular medicine (London, England), 1996, Volume: 1, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Female; Forearm; Humans; Hyperemia; Infusions, Intra-Arterial; Ischemia; Laser-Doppler Flowmetry; Male; Methacholine Chloride; Nitroprusside; omega-N-Methylarginine; Parasympathomimetics; Plethysmography; Regional Blood Flow; Skin; Vasodilation; Vasodilator Agents

1996
Bradykinin-induced bronchospasm in the rat in vivo: a role for nitric oxide modulation.
    The European respiratory journal, 1999, Volume: 13, Issue:2

    Topics: Airway Resistance; Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lung Compliance; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley

1999
Type II diabetes abrogates sex differences in endothelial function in premenopausal women.
    Circulation, 2000, May-02, Volume: 101, Issue:17

    Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Leg; Male; Methacholine Chloride; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Obesity; omega-N-Methylarginine; Premenopause; Risk Factors; Sex Characteristics; Vasodilator Agents

2000
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
    The European respiratory journal, 2000, Volume: 15, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea

2000
Aging increases PGHS-2-dependent vasoconstriction in rat mesenteric arteries.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:6

    Topics: Aging; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 2; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Isoenzymes; Mesenteric Arteries; Methacholine Chloride; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Vasoconstriction; Vasodilation

2000
Vascular function in alcohol-treated pregnant and nonpregnant mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; Fetus; Male; Mesenteric Arteries; Methacholine Chloride; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Parasympathomimetics; Phenylephrine; Pregnancy; Pregnancy, Animal; Vasoconstriction; Vasoconstrictor Agents

2001
Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels.
    American journal of hematology, 2003, Volume: 74, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Blood Vessels; Brachial Artery; Case-Control Studies; Cross-Over Studies; Enzyme Inhibitors; Female; Forearm; Humans; Injections, Intra-Arterial; Male; Methacholine Chloride; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Ultrasonography; Vascular Resistance; Vasodilation; Vasodilator Agents

2003
Effect of high-salt diet on NO release and superoxide production in rat aorta.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:2

    Topics: Animals; Aorta; In Vitro Techniques; Male; Methacholine Chloride; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Superoxides; Xanthine Oxidase

2004
Role of nitric oxide in methacholine-induced sweating and vasodilation in human skin.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 100, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Forearm; Humans; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Regional Blood Flow; Skin; Sweating; Time Factors; Vasodilation

2006