Page last updated: 2024-09-03

omega-n-methylarginine and ketorolac

omega-n-methylarginine has been researched along with ketorolac in 9 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(ketorolac)
Trials
(ketorolac)
Recent Studies (post-2010) (ketorolac)
4,4113443361,778668725

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)ketorolac (IC50)
Prostaglandin G/H synthase 1Homo sapiens (human)0.013
Caspase-1Homo sapiens (human)1.3025
Prostaglandin G/H synthase 2Homo sapiens (human)0.282
Caspase-3Homo sapiens (human)1.3025
Caspase-4Homo sapiens (human)1.3025
Caspase-5Homo sapiens (human)1.3025
Caspase-9Homo sapiens (human)1.3025
Cell division control protein 42 homologHomo sapiens (human)2
Ras-related C3 botulinum toxin substrate 1Homo sapiens (human)2

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Abdelazeem, AH; Khan, SI; McCurdy, CR; Sufka, KJ; White, SW1
Casey, DP; Joyner, MJ1
Augeri, AL; Kiernan, FJ; Parker, BA; Polk, DM; Thompson, PD; Tschakovsky, ME1
Crecelius, AR; Dinenno, FA; Kirby, BS; Larson, DG; Luckasen, GJ1
Casey, DP; Joyner, MJ; Lopez, MG; Silva, BM1
Eldridge, MW; Harrell, JW; Johansson, RE; Kellawan, JM; Schrage, WG; Sebranek, JJ; Walker, BJ1
Crecelius, AR; Dinenno, FA; Hearon, CM; Kirby, BS; Larson, DG; Luckasen, GJ1
Eldridge, MW; Harrell, JW; Johansson, RE; Kellawan, JM; Limberg, JK; Peltonen, GL; Schrage, WG; Sebranek, JJ1
Carter, KJ; Eldridge, MW; Harrell, JW; Johansson, RE; Kellawan, JM; Limberg, JK; Peltonen, GL; Schrage, WG; Sebranek, JJ; Walker, BJ1

Trials

3 trial(s) available for omega-n-methylarginine and ketorolac

ArticleYear
ATP-mediated vasodilatation occurs via activation of inwardly rectifying potassium channels in humans.
    The Journal of physiology, 2012, Nov-01, Volume: 590, Issue:21

    Topics: Acetylcholine; Adenosine Triphosphate; Adult; Barium Compounds; Chlorides; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Ketorolac; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ouabain; Potassium Channels, Inwardly Rectifying; Potassium Chloride; Sodium-Potassium-Exchanging ATPase; Vasodilation; Vasodilator Agents; Young Adult

2012
Roles of nitric oxide and prostaglandins in the hyperemic response to a maximal metabolic stimulus: redundancy prevails.
    European journal of applied physiology, 2013, Volume: 113, Issue:6

    Topics: Blood Pressure; Enzyme Inhibitors; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Ischemia; Ketorolac; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Regional Blood Flow; Young Adult

2013
Contracting human skeletal muscle maintains the ability to blunt α1 -adrenergic vasoconstriction during KIR channel and Na(+) /K(+) -ATPase inhibition.
    The Journal of physiology, 2015, Jun-15, Volume: 593, Issue:12

    Topics: Adenosine; Adult; Barium Compounds; Brachial Artery; Chlorides; Exercise; Female; Forearm; Hand Strength; Humans; Ketorolac; Male; Muscle Contraction; Muscle, Skeletal; omega-N-Methylarginine; Ouabain; Potassium Channels, Inwardly Rectifying; Propranolol; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Young Adult

2015

Other Studies

6 other study(ies) available for omega-n-methylarginine and ketorolac

ArticleYear
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Carrageenan; Cell Line, Tumor; Chlorocebus aethiops; Dimerization; Drug Design; Edema; Epithelial Cells; Hindlimb; Humans; Kidney; Macrophages; Mice; Molecular Docking Simulation; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Structure-Activity Relationship; Swine; Vero Cells

2015
Prostaglandins do not contribute to the nitric oxide-mediated compensatory vasodilation in hypoperfused exercising muscle.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:1

    Topics: Acetylcholine; Blood Pressure; Brachial Artery; Catheterization; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Exercise; Forearm; Heart Rate; Humans; Hyperemia; Ketorolac; Male; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Regional Blood Flow; Vasodilation; Vasodilator Agents; Vital Capacity; Young Adult

2011
Heterogenous vasodilator pathways underlie flow-mediated dilation in men and women.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Adult; Analysis of Variance; Blood Flow Velocity; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Hyperemia; Infusions, Intra-Arterial; Ketorolac; Laser-Doppler Flowmetry; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Radial Artery; Regional Blood Flow; Sex Factors; Ultrasonography; Vasodilation; Vasodilator Agents; Young Adult

2011
Exercise vasodilation is greater in women: contributions of nitric oxide synthase and cyclooxygenase.
    European journal of applied physiology, 2015, Volume: 115, Issue:8

    Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Exercise; Female; Forearm; Hemodynamics; Humans; Ketorolac; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Sex Characteristics; Ultrasonography; Vascular Resistance; Vasodilation; Young Adult

2015
β-Adrenergic-mediated vasodilation in young men and women: cyclooxygenase restrains nitric oxide synthase.
    American journal of physiology. Heart and circulatory physiology, 2016, Mar-15, Volume: 310, Issue:6

    Topics: Adrenergic beta-Agonists; Adult; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intra-Arterial; Isoproterenol; Ketorolac; Male; Microcirculation; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Sex Factors; Ultrasonography, Doppler; Vasodilation

2016
Preserved β-adrenergic-mediated vasodilation in skeletal muscle of young adults with obesity despite shifts in cyclooxygenase and nitric oxide synthase.
    American journal of physiology. Heart and circulatory physiology, 2022, 01-01, Volume: 322, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Blood Vessels; Cyclooxygenase Inhibitors; Female; Humans; Isoproterenol; Ketorolac; Male; Muscle, Skeletal; Nitric Oxide Synthase Type III; Obesity; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Receptors, Adrenergic, beta; Vasodilation

2022