Page last updated: 2024-09-03

omega-n-methylarginine and isoproterenol

omega-n-methylarginine has been researched along with isoproterenol in 59 studies

Compound Research Comparison

Studies (omega-n-methylarginine)	Trials (omega-n-methylarginine)	Recent Studies (post-2010) (omega-n-methylarginine)	Studies (isoproterenol)	Trials (isoproterenol)	Recent Studies (post-2010) (isoproterenol)
4,411	344	336	30,780	803	2,640

Protein Interaction Comparison

Protein	Taxonomy	isoproterenol (IC50)
Beta-2 adrenergic receptor	Homo sapiens (human)	0.246
Beta-1 adrenergic receptor	Homo sapiens (human)	0.333
Beta-2 adrenergic receptor	Rattus norvegicus (Norway rat)	0.2125
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	1.77
Beta-1 adrenergic receptor	Rattus norvegicus (Norway rat)	0.2125
Beta-3 adrenergic receptor	Rattus norvegicus (Norway rat)	0.2125
Beta-2 adrenergic receptor	Canis lupus familiaris (dog)	0.6667

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	37 (62.71)	18.2507
2000's	18 (30.51)	29.6817
2010's	3 (5.08)	24.3611
2020's	1 (1.69)	2.80

Authors

Authors	Studies
Förstermann, U; Helgren, MC; Kimber, ND; Klabunde, RE; Kuk, JE	1
Galligan, JJ; Osthaus, LE	1
Beierwaltes, WH; Carretero, OA	1
Giles, WR; Han, X; Shimoni, Y	1
Rozanski, GJ; Witt, RC	1
Chik, CL; Ho, AK; Murdoch, G; Ogiwara, T	1
Fedan, JS; Frazer, DG; Robinson, Va; Warner, TE; Yuan, LX	1
Jain, B; Robbins, RA; Rubinstein, I; Sisson, JH	1
Balligand, JL; Kelly, RA; Marsden, PA; Michel, T; Smith, TW	1
Jain, B; Leise, KL; Robbins, RA; Rubinstein, I; Sisson, JH	1
Chang, CH; Hsieh, HC; Hsieh, MJ; Kao, CL; Lin, PJ; Tsai, KT; Yao, PC	1
Matsukawa, K; Ninomiya, I; Shindo, T; Shirai, M	1
Mayhan, WG	1
Beierwaltes, WH	1
Kurtz, A; Scholz, H	1
Blankesteijn, WM; Thien, T	1
Böhm, M; Flesch, M; Kilter, H; Kuhn-Regnier, F; La Rosée, K; Lenz, O; Mädge, M; Schwinger, RH	1
Băck, N; Lumme, A; Soinila, J; Soinila, S; Vanhatalo, S	1
Anfossi, G; Cavalot, F; Hahn, AW; Massucco, P; Mattiello, L; Mularoni, EM; Trovati, M	1
Chesnais, JM; Fischmeister, R; Hartzell, HC; Hove-Madsen, L; Méry, PF	1
Finkel, MS; Oddis, CV	1
Chang, PC; van Veen, S	1
Ikeda, U; Kurosaki, K; Okada, K; Saito, T; Shimada, K; Shimpo, M	1
Cheng, K; Christodoulides, N; Durante, W; Peyton, KJ; Schafer, AI; Sunahara, RK	1
Barbato, E; Fontana, D; Iaccarino, G; Izzo, R; Lembo, G; Trimarco, B; Vecchione, C	1
Cannon, RO; Cardillo, C; Kilcoyne, CM; Panza, JA; Quyyumi, AA	2
Birder, LA; Finkel, MS; Kanai, AJ; Malinski, T; Mesaros, S; Oddis, CV	1
Hucks, D; Priest, RM; Ward, JP	1
Brodde, OE; Drexler, H; Hasenfuss, G; Kästner, S; Strobel, A; Studer, R	1
Balligand, JL; Bril, A; Gauthier, C; Khandoudi, N; Kobzik, L; Le Marec, H; Leblais, V; Trochu, JN	1
Choate, JK; Paterson, DJ; Sears, CE	1
Davies, CH; Harding, SE; Money-Kyrle, AM; Poole-Wilson, PA	1
Blaschke, TF; Chalon, S; Hoffman, BB; Moreno, H; Tejura, B; Urae, A	1
Dallinger, S; Eichler, HG; Polak, K; Schmetterer, L; Wolzt, M	1
Milstone, DS; Mortensen, RM; Sowell, MO; Vassilev, PM; Ye, C	1
Berdeaux, A; Bévérelli, F; Gauthier, C; Le Marec, H; Leblais, V; Rautureau, Y; Trochu, JN	1
Kang, KB; Majewski, H; van der Zypp, A	1
Hucks, D; Ward, JP	1
Delagrange, P; O'Rourke, ST; Scalbert, E; Vanhoutte, PM; Yang, Q	1
El-Omar, MM; Lanone, S; Li, JM; Mebazaa, A; Shah, AM; Tavernier, B; Trayer, IP; Yang, ZK	1
Huang, Y; Xu, B	1
Bryant, SM; Casadei, B; Rigg, L; Sears, CE; Terrar, DA	1
Gomez, RM; Levander, OA; Sterin-Borda, L	1
Abete, P; Cipolletta, E; De Santis, D; Ferrara, N; Iaccarino, G; Leosco, D; Pisani, E; Rengo, F; Sorriento, D; Trimarco, B; Trimarco, V	1
Ferro, A; Jackson, G; Ji, Y; O'Kane, PD; Queen, LR; Reebye, V; Stratton, P	1
Colledge, WH; Grace, AA; Joseph, SS; Kaumann, AJ; Lynham, JA; Molenaar, P	1
Diamond, J; Sandirasegarane, L	1
Dobrev, D; Francke, K; Grossmann, M; Kirch, W; Pittrow, D; Schindler, C	1
Chowdhary, S; Coote, JH; Marsh, AM; Townend, JN	1
Ahlers, BA; Kaye, DM; Parnell, MM; Schlaich, MP	1
Charkoudian, N; Eisenach, JH; Joyner, MJ; Martin, EA; Nicholson, WT	1
Huxley, VH; Sarelius, IH; Wang, JJ	1
Fang, Q; Finkel, MS; Jain, AC; Kan, H; Khanna, D; Underwood, BL; Williams, HJ; Xie, Z	1
Barbieri, SF; Brar, BK; Gattuso, A; Mahata, SK; Mannarino, C; Mazza, R; Tota, B	1
Hälinen, M; Haverinen, J; Vornanen, M	1
Carper, MJ; Clark, PD; Evans, CA; Galvin, VB; Garry, JP; Hickner, RC; Kemeny, G; McIver, KL	1
Eldridge, MW; Harrell, JW; Johansson, RE; Kellawan, JM; Limberg, JK; Peltonen, GL; Schrage, WG; Sebranek, JJ	1
Carter, KJ; Eldridge, MW; Harrell, JW; Johansson, RE; Kellawan, JM; Limberg, JK; Peltonen, GL; Schrage, WG; Sebranek, JJ; Walker, BJ	1

Trials

6 trial(s) available for omega-n-methylarginine and isoproterenol

Article	Year
Prostaglandins and nitric oxide mediate insulin-induced vasodilation in the human forearm. Cardiovascular research, 1997, Volume: 34, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Forearm; Humans; Indomethacin; Insulin; Isoproterenol; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Propranolol; Vascular Resistance; Vasodilation	1997
Role of nitric oxide in isoprenaline and sodium nitroprusside-induced relaxation in human hand veins. British journal of clinical pharmacology, 1999, Volume: 47, Issue:1 Topics: Adult; Bradykinin; Enzyme Inhibitors; Female; Hand; Humans; Isoproterenol; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Time Factors; Vasoconstriction; Vasodilation; Veins	1999
Systemic NO synthase inhibition blunts the chronotropic, but not the inotropic response to isoprenaline in man. Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:3 Topics: Adult; Blood Pressure; Breath Tests; Cross-Over Studies; Diastole; Double-Blind Method; Enzyme Inhibitors; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Placebos; Pulse; Reference Values; Systole	1999
Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment. Cardiovascular research, 2003, Jul-01, Volume: 59, Issue:1 Topics: Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Aspirin; Blood Platelets; Citrulline; Cyclooxygenase Inhibitors; Drug Administration Schedule; Female; Humans; Indomethacin; Isoproterenol; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors	2003
Nitric oxide and cardiac muscarinic control in humans. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5 Topics: Adolescent; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Adult; Bradycardia; Cardiotonic Agents; Cholinesterase Inhibitors; Cross-Over Studies; Edrophonium; Enzyme Inhibitors; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Male; Muscarinic Agonists; Nitric Oxide; omega-N-Methylarginine; Parasympathetic Nervous System; Phenylephrine; Receptors, Muscarinic; Single-Blind Method; Species Specificity; Sympathetic Nervous System; Vasoconstrictor Agents	2004
beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine. Journal of hypertension, 2004, Volume: 22, Issue:10 Topics: Acetylcholine; Adult; Arginine; Drug Synergism; Enzyme Inhibitors; Forearm; Humans; Hypertension; Isoproterenol; Male; Medical Records; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Receptors, Adrenergic, beta; Regional Blood Flow; Vasodilation; Vasodilator Agents	2004

Other Studies

53 other study(ies) available for omega-n-methylarginine and isoproterenol

Article	Year
NG-methyl-L-arginine decreases contractility, cGMP and cAMP in isoproterenol-stimulated rat hearts in vitro. European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1 Topics: Animals; Arginine; Coronary Circulation; Cyclic AMP; Cyclic GMP; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley	1992
Antagonists of nitric oxide synthesis inhibit nerve-mediated relaxations of longitudinal muscle in guinea pig ileum. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guinea Pigs; Ileum; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Papaverine	1992
Nonprostanoid endothelium-derived factors inhibit renin release. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl Topics: Animals; Arginine; Endothelins; In Vitro Techniques; Isoproterenol; Kidney Cortex; Male; Melitten; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Renin	1992
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate. The Journal of general physiology, 1995, Volume: 106, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides	1995
IL-1 inhibits beta-adrenergic control of cardiac calcium current: role of L-arginine/nitric oxide pathway. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Animals; Arginine; Calcium Channels; Cells, Cultured; Colforsin; Guinea Pigs; Heart; Heart Ventricles; Humans; Interleukin-1; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, beta; Recombinant Proteins	1994
Tyrosine kinase inhibitors enhance cGMP production in rat pinealocytes. Biochemical and biophysical research communications, 1995, Feb-27, Volume: 207, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Catechols; Cyclic AMP; Cyclic GMP; Genistein; Hydroquinones; Isoflavones; Isoproterenol; Male; Nitric Oxide Synthase; Nitriles; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrphostins	1995
Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3 Topics: Airway Resistance; Amino Acid Oxidoreductases; Animals; Arginine; Epithelium; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Male; Methacholine Chloride; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Penicillamine; Respiration; S-Nitroso-N-Acetylpenicillamine; Trachea	1995
TNF-alpha and IL-1 beta upregulate nitric oxide-dependent ciliary motility in bovine airway epithelium. The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1 Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Bronchi; Cattle; Cell Survival; Cells, Cultured; Cilia; Culture Media, Conditioned; Epithelial Cells; Epithelium; Humans; Interleukin-1; Isoproterenol; Kinetics; Macrophages, Alveolar; Movement; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha; Videotape Recording	1995
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1 Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction	1993
Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochemical and biophysical research communications, 1993, Feb-26, Volume: 191, Issue:1 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Bronchi; Cattle; Cilia; Epithelium; In Vitro Techniques; Isomerism; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Substance P	1993
Enhancement of endothelium-dependent contraction of the canine coronary artery by UW solution. Transplantation, 1994, Dec-27, Volume: 58, Issue:12 Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Arginine; Cell Communication; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Glutathione; Hypoxia; Insulin; Isoproterenol; Male; Nitric Oxide; omega-N-Methylarginine; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose; Time Factors; Vasoconstriction; Vasodilation	1994
Nitric oxide mediates cat hindlimb cholinergic vasodilation induced by stimulation of posterior hypothalamus. The Japanese journal of physiology, 1993, Volume: 43, Issue:4 Topics: Animals; Arginine; Atropine; Cats; Cholinergic Fibers; Electric Stimulation; Hemodynamics; Hindlimb; Hypothalamus, Posterior; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Receptors, Adrenergic, beta; Vasodilation	1993
Responses of cerebral arterioles to activation of beta-adrenergic receptors during diabetes mellitus. Stroke, 1994, Volume: 25, Issue:1 Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Rats; Receptors, Adrenergic, beta; Vasodilation	1994
Nitric oxide participates in calcium-mediated regulation of renin release. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl Topics: Angiotensin II; Animals; Arginine; Calcium; Calmodulin; Egtazic Acid; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides	1994
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney. The Journal of clinical investigation, 1993, Volume: 91, Issue:3 Topics: Acetylcholine; Angiotensin I; Animals; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; In Vitro Techniques; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Perfusion; Pressure; Rats; Rats, Inbred Strains; Renin	1993
Effect of NG-monomethyl-L-arginine on the beta-adrenoceptor-mediated relaxation of rat mesenteric resistance arteries. Life sciences, 1993, Volume: 52, Issue:16 Topics: Animals; Arginine; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta	1993
Evidence against a role of nitric oxide in the indirect negative inotropic-effect of M-cholinoceptor stimulation in human ventricular myocardium. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3 Topics: Arginine; Carbachol; Cyclic GMP; Humans; Isoproterenol; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Papillary Muscles; Receptors, Cholinergic	1995
Nitric oxide synthase in the autonomic and sensory ganglia innervating the submandibular salivary gland. Microscopy research and technique, 1996, Sep-01, Volume: 35, Issue:1 Topics: Animals; Autonomic Pathways; Biomarkers; Carbachol; Ganglia, Parasympathetic; Ganglia, Sympathetic; Immunohistochemistry; Isoproterenol; NADPH Dehydrogenase; Nerve Endings; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Submandibular Gland	1996
Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: dependence on cyclic guanosine monophosphate and modulation of catecholamine effects. Diabetologia, 1996, Volume: 39, Issue:10 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analysis of Variance; Arterioles; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; Insulin; Isoproterenol; Kinetics; Methylene Blue; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Propranolol; Receptors, Adrenergic, beta; Recombinant Proteins; Yohimbine	1996
Nitric oxide synthase does not participate in negative inotropic effect of acetylcholine in frog heart. The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2 Topics: Acetylcholine; Animals; Arginine; Calcium; Electric Conductivity; Isoproterenol; Kinetics; Muscarine; Myocardial Contraction; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Patch-Clamp Techniques; Rana catesbeiana; Rana esculenta	1996
Cytokines and nitric oxide synthase inhibitor as mediators of adrenergic refractoriness in cardiac myocytes. European journal of pharmacology, 1997, Feb-12, Volume: 320, Issue:2-3 Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Cytokines; Drug Interactions; Drug Resistance; Enzyme Induction; Enzyme Inhibitors; Heart; Heart Rate; Isoproterenol; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Rats	1997
Adenosine stimulates nitric oxide synthesis in rat cardiac myocytes. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Dactinomycin; Enzyme Inhibitors; Heart; Humans; Interleukin-1; Isoproterenol; Myocardium; Naphthalenes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Stereoisomerism; Theophylline; Xanthines	1997
cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: Animals; Aorta; Blood Platelets; Bucladesine; Carbon Monoxide; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoproterenol; Muscle, Smooth, Vascular; omega-N-Methylarginine; Polymerase Chain Reaction; Protoporphyrins; Rats; RNA, Messenger; Transcription, Genetic	1997
Insulin modulation of an endothelial nitric oxide component present in the alpha2- and beta-adrenergic responses in human forearm. The Journal of clinical investigation, 1997, Oct-15, Volume: 100, Issue:8 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Azepines; Brachial Artery; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intra-Arterial; Insulin; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Regional Blood Flow; Vasoconstrictor Agents; Vasodilator Agents	1997
Decreased vasodilator response to isoproterenol during nitric oxide inhibition in humans. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:4 Topics: Adrenergic beta-Agonists; Adult; Blood Vessels; Enzyme Inhibitors; Female; Forearm; Humans; Isoproterenol; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Vasodilation	1997
Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes. The American journal of physiology, 1997, Volume: 273, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Animals, Newborn; Bucladesine; Calcimycin; Cells, Cultured; Dobutamine; Enzyme Induction; Guanosine Diphosphate; Heart; Interleukin-1; Isoproterenol; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Receptors, Adrenergic, beta; Terbutaline; Thionucleotides; Trifluoperazine	1997
Noradrenaline, beta-adrenoceptor mediated vasorelaxation and nitric oxide in large and small pulmonary arteries of the rat. British journal of pharmacology, 1997, Volume: 122, Issue:7 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Dinoprost; Dose-Response Relationship, Drug; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Oxytocics; Propanolamines; Propranolol; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vasoconstriction; Vasoconstrictor Agents; Vasodilation	1997
Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilation in patients with essential hypertension. Circulation, 1998, Mar-10, Volume: 97, Issue:9 Topics: Acetylcholine; Adrenergic beta-Agonists; Case-Control Studies; Endothelium, Vascular; Female; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Reference Values; Vasodilation	1998
Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart. Journal of the American College of Cardiology, 1998, Volume: 32, Issue:4 Topics: Adrenergic beta-Agonists; Enzyme Inhibitors; Heart Failure; Humans; In Vitro Techniques; Isoproterenol; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Polymerase Chain Reaction; Stimulation, Chemical; Transcription, Genetic	1998
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle. The Journal of clinical investigation, 1998, Oct-01, Volume: 102, Issue:7 Topics: Adrenergic beta-Agonists; Arginine; Cyclic GMP; Ethanolamines; Female; Heart; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3	1998
Effect of nitric oxide synthase inhibition on the sympatho-vagal contol of heart rate. Journal of the autonomic nervous system, 1998, Aug-27, Volume: 73, Issue:1 Topics: Adrenergic Fibers; Animals; Arginine; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Indazoles; Isoproterenol; Male; Neural Inhibition; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Polymethacrylic Acids; Propranolol; Rabbits; Sympatholytics; Sympathomimetics; Vagus Nerve	1998
An inhibitor of nitric oxide synthase does not increase contraction or beta-adrenoceptor sensitivity of ventricular myocytes from failing human heart. Cardiovascular research, 1998, Volume: 40, Issue:3 Topics: Adrenergic beta-Agonists; Adult; Aged; Analysis of Variance; Cell Size; Cells, Cultured; Child; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Diseases; Humans; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, beta	1998
Galpha(i2), Galpha(i3)and Galpha(o) are all required for normal muscarinic inhibition of the cardiac calcium channels in nodal/atrial-like cultured cardiocytes. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:9 Topics: Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cell Line; GTP-Binding Proteins; Heart; Heart Ventricles; Isoproterenol; Mice; Models, Cardiovascular; Molsidomine; Muscarinic Antagonists; Myocardium; Nifedipine; Nitric Oxide Donors; omega-N-Methylarginine; Pertussis Toxin; Receptors, Muscarinic; Stem Cells; Virulence Factors, Bordetella	1999
Beta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta. British journal of pharmacology, 1999, Volume: 128, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Nadolol; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tetrahydronaphthalenes; Vasoconstriction; Vasodilation	1999
Age-related involvement of the endothelium in beta-adrenoceptor-mediated relaxation of rat aorta. European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Apamin; Atenolol; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Peptides; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasoconstriction; Vasodilation	2000
Critical dependence of the NO-mediated component of cyclic AMP-induced vasorelaxation on extracellular L-arginine in pulmonary arteries of the rat. British journal of pharmacology, 2000, Volume: 130, Issue:5 Topics: Animals; Arginine; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation	2000
Melatonin potentiates contractile responses to serotonin in isolated porcine coronary arteries. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Melatonin; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Swine; Vasoconstrictor Agents; Vasodilator Agents	2001
Cardiac contractile impairment associated with increased phosphorylation of troponin I in endotoxemic rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:2 Topics: Actin Cytoskeleton; Animals; Calcium; Cytosol; Endotoxemia; Heart; Heart Ventricles; Homeostasis; Hydrogen-Ion Concentration; Isoproterenol; Lipopolysaccharides; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Phosphorylation; Rats; Troponin I	2001
Different mechanisms mediate beta adrenoceptor stimulated vasorelaxation of coronary and femoral arteries. Acta pharmacologica Sinica, 2000, Volume: 21, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Arteries; Coronary Vessels; Endothelium, Vascular; Female; Femoral Artery; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Propanolamines; Swine; Vasodilation	2000
Nitric oxide does not modulate the hyperpolarization-activated current, I(f), in ventricular myocytes from spontaneously hypertensive rats. Cardiovascular research, 2001, Volume: 51, Issue:1 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amphotericin B; Analysis of Variance; Animals; Arrhythmias, Cardiac; Cardiomegaly; Colforsin; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Isoproterenol; Male; Membrane Potentials; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Oxadiazoles; Patch-Clamp Techniques; Penicillamine; Pyridines; Rats; Rats, Inbred SHR; Sinoatrial Node	2001
Reduced inotropic heart response in selenium-deficient mice relates with inducible nitric oxide synthase. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminopyridines; Animals; Diet; Female; Heart Atria; Isoproterenol; Male; Mice; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Norepinephrine; omega-N-Methylarginine; Selenium	2003
Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1 Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Blotting, Western; Body Weight; Brimonidine Tartrate; Carotid Arteries; Cells, Cultured; Cytosol; Endothelium, Vascular; Enzyme Inhibitors; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Organ Size; Physical Conditioning, Animal; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vasodilator Agents	2003
Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Animals; Binding Sites; CHO Cells; Cricetinae; Cyclic AMP; Drug Interactions; Drug Resistance; Female; Heart; Heart Atria; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Norepinephrine; omega-N-Methylarginine; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Recombinant Proteins; Stereoisomerism; Sympathomimetics	2003
Pertussis toxin-sensitive G protein but not NO/cGMP pathway mediates the negative inotropic effect of carbachol in adult rat cardiomyocytes. Pharmacology, 2004, Volume: 70, Issue:1 Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; GTP-Binding Proteins; Injections, Intraperitoneal; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Time Factors	2004
Mechanisms of beta-adrenergic receptor-mediated venodilation in humans. Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:1 Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adult; Aspirin; Bisoprolol; Dose-Response Relationship, Drug; Endothelium, Vascular; Glyburide; Hand; Humans; Isoproterenol; Male; Methylene Blue; omega-N-Methylarginine; Potassium Chloride; Receptors, Adrenergic, beta-2; Tetraethylammonium; Vasodilation; Veins	2004
Bimodal distribution of vasodilator responsiveness to adenosine due to difference in nitric oxide contribution: implications for exercise hyperemia. Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:2 Topics: Acetylcholine; Adenosine; Adult; Brachial Artery; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exercise; Female; Forearm; Humans; Hyperemia; Isoproterenol; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation; Vasodilator Agents	2006
Adaptation of coronary microvascular exchange in arterioles and venules to exercise training and a role for sex in determining permeability responses. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2 Topics: Adaptation, Physiological; Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Albumins; Animals; Arterioles; Atrial Natriuretic Factor; Capillary Permeability; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Physical Endurance; Research Design; Sex Factors; Signal Transduction; Swine; Swine, Miniature; Venules	2007
Inducible nitric oxide synthase attenuates adrenergic signaling in alcohol fed rats. Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:6 Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Blotting, Western; Caloric Restriction; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Ethanol; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Ventricular Dysfunction, Left; Ventricular Pressure	2007
Catestatin (chromogranin A344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:1 Topics: Animals; Calcium-Binding Proteins; Cardiotonic Agents; Cattle; Chromogranin A; Depression, Chemical; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Oxadiazoles; Peptide Fragments; Phosphorylation; Piperidines; Quinoxalines; Rana esculenta; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke Volume	2008
Sinoatrial tissue of crucian carp heart has only negative contractile responses to autonomic agonists. BMC physiology, 2010, Jun-11, Volume: 10 Topics: Acclimatization; Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Carps; Cholinergic Agonists; Cold Temperature; Enzyme Inhibitors; Heart Rate; Hot Temperature; Hypoxia; Isoproterenol; Myocardial Contraction; Nifedipine; Nitric Oxide Synthase; omega-N-Methylarginine; Parasympathetic Nervous System; Potassium Channels; Seasons; Sinoatrial Node; Species Specificity; Sympathetic Nervous System	2010
In vivo nitric oxide suppression of lipolysis in subcutaneous abdominal adipose tissue is greater in obese than lean women. Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:6 Topics: Adult; Fasting; Fatty Acids, Nonesterified; Female; Humans; Isoproterenol; Lipolysis; Microdialysis; Nitric Oxide; Norepinephrine; Obesity; omega-N-Methylarginine; Sedentary Behavior; Subcutaneous Fat, Abdominal; Young Adult	2012
β-Adrenergic-mediated vasodilation in young men and women: cyclooxygenase restrains nitric oxide synthase. American journal of physiology. Heart and circulatory physiology, 2016, Mar-15, Volume: 310, Issue:6 Topics: Adrenergic beta-Agonists; Adult; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intra-Arterial; Isoproterenol; Ketorolac; Male; Microcirculation; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Sex Factors; Ultrasonography, Doppler; Vasodilation	2016
Preserved β-adrenergic-mediated vasodilation in skeletal muscle of young adults with obesity despite shifts in cyclooxygenase and nitric oxide synthase. American journal of physiology. Heart and circulatory physiology, 2022, 01-01, Volume: 322, Issue:1 Topics: Adrenergic beta-Agonists; Adult; Blood Vessels; Cyclooxygenase Inhibitors; Female; Humans; Isoproterenol; Ketorolac; Male; Muscle, Skeletal; Nitric Oxide Synthase Type III; Obesity; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Receptors, Adrenergic, beta; Vasodilation	2022