Page last updated: 2024-09-03

omega-n-methylarginine and ibuprofen

omega-n-methylarginine has been researched along with ibuprofen in 8 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(ibuprofen)
Trials
(ibuprofen)
Recent Studies (post-2010) (ibuprofen)
4,41134433610,2451,7814,267

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)ibuprofen (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)2.9
Prostaglandin G/H synthase 2 Bos taurus (cattle)1.1
AlbuminBos taurus (cattle)3
Prostaglandin G/H synthase 1Ovis aries (sheep)4.0919
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.22
Prostaglandin G/H synthase 1Homo sapiens (human)1.6273
Caspase-1Homo sapiens (human)7.2667
Substance-P receptorCavia porcellus (domestic guinea pig)1.1
Prostaglandin G/H synthase 2Homo sapiens (human)3.0687
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)1.3
Aldo-keto reductase family 1 member C3Homo sapiens (human)10
Caspase-3Homo sapiens (human)7.2667
Caspase-4Homo sapiens (human)7.2667
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)1.1
Caspase-5Homo sapiens (human)7.2667
Caspase-9Homo sapiens (human)7.2667
Prostaglandin G/H synthase 2Ovis aries (sheep)1.1375
Mu-type opioid receptorCavia porcellus (domestic guinea pig)2.9
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)5
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.54
Solute carrier family 22 member 6Homo sapiens (human)8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)1.3

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gray, DW; Marshall, I1
Cai, B; Greenberg, S; Hyman, A; Kolls, J; Lippton, H; Nelson, S; Summer, WR; Wang, Y; Xie, J1
Dietz, NM; Engelke, KA; Halliwill, JR; Joyner, MJ; Proctor, DN1
Bani, D; Ciuffi, M; Failli, P; Franchi-Micheli, S; Mazzetti, L; Zilletti, L1
Büssemaker, E; Fauler, J; Fleming, I; Gross, P; Lässig, G; Passauer, J; Pistrosch, F1
Goto, M; Hiramatsu, O; Kajiya, F; Mori, H; Ogasawara, Y; Shimokawa, H; Shinozaki, Y; Yada, T1
Black, MJ; Clyman, RI; Gubhaju, L; McCurnin, D; Seidner, S; Sutherland, MR; Yoder, BA1
Goto, M; Hiramatsu, O; Kajiya, F; Ogasawara, Y; Shimokawa, H; Yada, T1

Trials

2 trial(s) available for omega-n-methylarginine and ibuprofen

ArticleYear
Contribution of nitric oxide and prostaglandins to reactive hyperemia in human forearm.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Hyperemia; Ibuprofen; Ischemia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Regional Blood Flow; Vasodilator Agents

1996
Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole.
    Clinical science (London, England : 1979), 2003, Volume: 105, Issue:4

    Topics: Adult; Analysis of Variance; Aryl Hydrocarbon Hydroxylases; Bradykinin; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Forearm; Humans; Ibuprofen; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Sulfaphenazole; Vasodilator Agents

2003

Other Studies

6 other study(ies) available for omega-n-methylarginine and ibuprofen

ArticleYear
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Ibuprofen; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains

1992
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Cattle; Endothelium, Vascular; Histamine; Ibuprofen; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Pentoxifylline; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents

1993
Mechanical stretch reveals different components of endothelial-mediated vascular tone in rat aortic strips.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Guanylate Cyclase; Ibuprofen; In Vitro Techniques; Indoles; Indomethacin; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Stress, Mechanical; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2000
Important role of endogenous hydrogen peroxide in pacing-induced metabolic coronary vasodilation in dogs in vivo.
    Journal of the American College of Cardiology, 2007, Sep-25, Volume: 50, Issue:13

    Topics: Animals; Antioxidants; Cardiac Pacing, Artificial; Catalase; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Dogs; Enzyme Inhibitors; Female; Hydrogen Peroxide; Ibuprofen; Male; Microcirculation; Microscopy, Fluorescence; Myocardium; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Potassium Channel Blockers; Tetraethylammonium; Theophylline; Vasodilation; Vasodilator Agents

2007
Effects of ibuprofen treatment on the developing preterm baboon kidney.
    American journal of physiology. Renal physiology, 2012, May-15, Volume: 302, Issue:10

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Drinking; Drug Interactions; Ductus Arteriosus, Patent; Enzyme Inhibitors; Female; Ibuprofen; Kidney; Kidney Glomerulus; Nephrons; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Size; Papio; Pregnancy; Premature Birth; Urine

2012
Role of endogenous hydrogen peroxide during angiotensin type 1 receptor blockers administration in pacing-induced metabolic coronary vasodilatation in dogs in vivo.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2013, Volume: 2013

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Biological Factors; Cardiac Pacing, Artificial; Catalase; Coronary Vessels; Deoxyguanosine; Diabetes Mellitus, Experimental; Dogs; Female; Hydrogen Peroxide; Ibuprofen; Imidazoles; Infusions, Intravenous; Male; Microcirculation; Myocardium; omega-N-Methylarginine; Superoxide Dismutase; Tetrazoles; Vasodilation

2013