Page last updated: 2024-09-03

omega-n-methylarginine and fluconazole

omega-n-methylarginine has been researched along with fluconazole in 8 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(fluconazole)
Trials
(fluconazole)
Recent Studies (post-2010) (fluconazole)
4,4113443369,3437213,664

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)fluconazole (IC50)
Lanosterol 14-alpha demethylaseCandida albicans SC53140.1296
Cytochrome P450 2C9 Homo sapiens (human)9.21
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.88

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellien, J; Bourkaib, R; Eltchaninoff, H; Iacob, M; Joannides, R; Thuillez, C1
Bellien, J; Joannides, R; Thuillez, C1
Bellien, J; Favre, J; Gao, J; Iacob, M; Joannidès, R; Richard, V; Thuillez, C1
Bellien, J; Dreano, Y; Gutierrez, L; Iacob, M; Joannides, R; Lucas, D; Mercier, A; Monteil, C; Remy-Jouet, I; Thuillez, C; Vendeville, C1
Bellien, J; Blot, E; Donnadieu, N; Dreano, Y; Gutierrez, L; Iacob, M; Joannides, R; Lucas, D; Mercier, A; Remy-Jouet, I; Thuillez, C1
Herr, MD; Leuenberger, UA; Sinoway, LI; Spilk, S1
De Staercke, C; Hayek, S; Hooper, WC; Kavtaradze, N; Lin, J; Manatunga, A; Murrow, JR; Ozkor, MA; Quyyumi, AA; Rahman, AM1
Bellien, J; Djerada, Z; Duflot, T; Iacob, M; Joannides, R; Remy-Jouet, I; Roca, F; Wils, J1

Trials

5 trial(s) available for omega-n-methylarginine and fluconazole

ArticleYear
AT1 receptor blockade prevents the decrease in conduit artery flow-mediated dilatation during NOS inhibition in humans.
    Clinical science (London, England : 1979), 2007, Volume: 112, Issue:7

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Benzimidazoles; Benzoates; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Fluconazole; Humans; Male; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Radial Artery; Regional Blood Flow; Telmisartan; Vascular Resistance; Vasodilation; Vasodilator Agents

2007
Role of endothelium-derived hyperpolarizing factor in the regulation of radial artery basal diameter and endothelium-dependent dilatation in vivo.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:4

    Topics: Biological Factors; Endothelium; Fluconazole; Hot Temperature; Humans; Male; omega-N-Methylarginine; Radial Artery; Tetraethylammonium; Vasodilation

2008
Arterial stiffness is regulated by nitric oxide and endothelium-derived hyperpolarizing factor during changes in blood flow in humans.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adult; Animals; Benzimidazoles; Biological Factors; Blood Pressure; Elasticity; Endothelium, Vascular; Enzyme Inhibitors; Fluconazole; Hot Temperature; Humans; Hypertension; Indoles; Male; Mice; Mice, Inbred Strains; Nitric Oxide; omega-N-Methylarginine; Oximes; Potassium Channel Blockers; Radial Artery; Regional Blood Flow; Tetraethylammonium; Vasodilation; Young Adult

2010
Epoxyeicosatrienoic acids contribute with altered nitric oxide and endothelin-1 pathways to conduit artery endothelial dysfunction in essential hypertension.
    Circulation, 2012, Mar-13, Volume: 125, Issue:10

    Topics: 14-alpha Demethylase Inhibitors; Adult; Eicosanoids; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Female; Fluconazole; Hot Temperature; Humans; Hyperemia; Hypertension; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Pulsatile Flow; Radial Artery; Reactive Oxygen Species; Skin; Stress, Mechanical

2012
Endothelium-derived hyperpolarizing factor mediates bradykinin-stimulated tissue plasminogen activator release in humans.
    Journal of vascular research, 2014, Volume: 51, Issue:3

    Topics: Adult; Biological Factors; Bradykinin; Cytochrome P-450 Enzyme System; Female; Fluconazole; Forearm; Humans; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Potassium Channels, Calcium-Activated; Regional Blood Flow; Tetraethylammonium; Tissue Plasminogen Activator; Vasodilation

2014

Other Studies

3 other study(ies) available for omega-n-methylarginine and fluconazole

ArticleYear
Impaired role of epoxyeicosatrienoic acids in the regulation of basal conduit artery diameter during essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:6

    Topics: Adult; Blood Pressure; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Eicosanoids; Endothelium, Vascular; Essential Hypertension; Female; Fluconazole; Humans; Hypertension; Male; Middle Aged; omega-N-Methylarginine; Radial Artery; Regional Blood Flow; Vasoconstriction; Vasodilation

2012
Endothelium-derived hyperpolarizing factor contributes to hypoxia-induced skeletal muscle vasodilation in humans.
    American journal of physiology. Heart and circulatory physiology, 2013, Dec-01, Volume: 305, Issue:11

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Biological Factors; Blood Flow Velocity; Blood Pressure; Cytochrome P-450 CYP2C9; Endothelium, Vascular; Enzyme Inhibitors; Female; Fluconazole; Forearm; Heart Rate; Humans; Hypoxia; Infusions, Intra-Arterial; Male; Muscle, Skeletal; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Ventilation; Regional Blood Flow; Vasodilation

2013
Alteration in the availability of epoxyeicosatrienoic acids contributes with NO to the development of endothelial dysfunction in conduit arteries during aging.
    Atherosclerosis, 2018, Volume: 275

    Topics: Adult; Age Factors; Aged; Aging; Cytochrome P-450 Enzyme Inhibitors; Eicosanoids; Endothelium, Vascular; Female; Fluconazole; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Peripheral Arterial Disease; Radial Artery; Ultrasonography, Doppler; Vasodilation; Young Adult

2018