omega-n-methylarginine has been researched along with diclofenac in 14 studies
| Studies (omega-n-methylarginine) | Trials (omega-n-methylarginine) | Recent Studies (post-2010) (omega-n-methylarginine) | Studies (diclofenac) | Trials (diclofenac) | Recent Studies (post-2010) (diclofenac) |
|---|---|---|---|---|---|
| 4,411 | 344 | 336 | 8,874 | 1,874 | 3,616 |
| Protein | Taxonomy | omega-n-methylarginine (IC50) | diclofenac (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 1.9 | |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.003 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 1.3376 | |
| Interleukin-8 | Homo sapiens (human) | 0.008 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0415 | |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 0.5 | |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | 0.012 | |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | 0.5 | |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | 0.5 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.4165 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 0.5 | |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | 0.5 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.6867 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.0502 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 4 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 0.5 | |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X | 1 |
| Ferreira, SH; Tonussi, CR | 1 |
| Oyanagui, Y | 1 |
| Cantabrana, B; Hidalgo, A; Menéndez Antolin, L; Pérez Vallina, JR; Sánchez, M | 1 |
| Hamilton, LC; Warner, TD | 1 |
| Allolio, B; Ernst, R; Horn, M; Hügel, S; Lie, SZ; Neubauer, S; Reincke, M; Schmidt, HH | 1 |
| Boulanger, CM; Ebrahimian, T; Henry, P; Mallat, Z; Mathieu, E; Scoazec, A; Tedgui, A | 1 |
| Ding, Z; Gödecke, A; Schrader, J; Ziegler, M | 1 |
| Grosser, N; Schröder, H | 1 |
| Lenasi, H; Strucl, M | 1 |
| Bek, T; Petersen, L | 4 |
2 trial(s) available for omega-n-methylarginine and diclofenac
| Article | Year |
|---|---|
The diameter response of retinal arterioles in diabetic maculopathy is reduced during hypoxia and is unaffected by the inhibition of cyclo-oxygenase and nitric oxide synthesis.
Topics: Adult; Aged; Arterioles; Cyclooxygenase Inhibitors; Diabetic Retinopathy; Diclofenac; Female; Follow-Up Studies; Humans; Hypoxia; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Ophthalmic Solutions; Regional Blood Flow; Retinal Artery; Retrospective Studies; Tomography, Optical Coherence; Vasodilation; Young Adult | 2016 |
Post-hypoxic constriction of retinal arterioles is impaired during nitric oxide and cyclo-oxygenase inhibition and in diabetic patients without retinopathy.
Topics: Adult; Arterioles; Cyclooxygenase Inhibitors; Diabetic Retinopathy; Diclofenac; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Hypoxia; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Retinal Vessels; Vasoconstriction; Young Adult | 2017 |
12 other study(ies) available for omega-n-methylarginine and diclofenac
| Article | Year |
|---|---|
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 2008 |
Mechanism of diclofenac analgesia: direct blockade of inflammatory sensitization.
Topics: Analgesia; Animals; Arginine; Carrageenan; Diclofenac; Dinoprostone; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Hyperalgesia; Indomethacin; Inflammation; Injections, Intra-Articular; Knee Injuries; Male; Methylene Blue; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar | 1994 |
Nitric oxide and superoxide radical are involved in both initiation and development of adjuvant arthritis in rats.
Topics: Administration, Oral; Animals; Arginine; Arthritis, Experimental; Diclofenac; Female; Injections, Intraperitoneal; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Superoxide Dismutase; Superoxides | 1994 |
Nitric oxide and cyclic nucleotides participate in the relaxation of diclofenac on rat uterine smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Enzyme Inhibitors; Female; GTP-Binding Proteins; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Nucleotides, Cyclic; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Rats, Wistar; Sensitivity and Specificity; Sulfonamides; Uterine Contraction; Uterus; Vanadates; Vasodilator Agents; Virulence Factors, Bordetella | 1998 |
Interactions between inducible isoforms of nitric oxide synthase and cyclo-oxygenase in vivo: investigations using the selective inhibitors, 1400W and celecoxib.
Topics: 6-Ketoprostaglandin F1 alpha; Amidines; Analysis of Variance; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylamines; Celecoxib; Crotonates; Cyclooxygenase 2; Dexamethasone; Diclofenac; Enzyme Inhibitors; Hydroxybutyrates; Isoenzymes; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitriles; Nitrites; Nitrogen Dioxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Toluidines | 1998 |
Multiple mechanisms are involved in the acute vasodilatory effect of 17beta-estradiol in the isolated perfused rat heart.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coronary Vessels; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Heart Ventricles; In Vitro Techniques; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rheology; Sex Factors; Stereoisomerism; Time Factors; Vasodilation | 1999 |
Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction.
Topics: Adult; Animals; Aorta; Cell Membrane; Cell Membrane Structures; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Ionophores; Male; Middle Aged; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Particle Size; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Endothelial dysfunction of coronary resistance vessels in apoE-/- mice involves NO but not prostacyclin-dependent mechanisms.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Apolipoproteins E; Bradykinin; Cholesterol, LDL; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Hypercholesterolemia; Iloprost; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Superoxide Dismutase; Vascular Resistance; Vasodilator Agents | 2002 |
Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway.
Topics: Animals; Aspirin; Cattle; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic N-Oxides; Cytoprotection; Diclofenac; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrogen Peroxide; Imidazoles; Indomethacin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine | 2003 |
The effect of nitric oxide synthase and cyclooxygenase inhibition on cutaneous microvascular reactivity.
Topics: Acetylcholine; Adult; Biological Factors; Blood Flow Velocity; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Inhibitors; Epoprostenol; Forearm; Humans; Injections, Intradermal; Iontophoresis; Laser-Doppler Flowmetry; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Skin; Time Factors; Vasodilation; Vasodilator Agents | 2008 |
Diameter changes of retinal arterioles during acute hypoxia in vivo are modified by the inhibition of nitric oxide and prostaglandin synthesis.
Topics: Acute Disease; Adult; Arterioles; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Inhibitors; Exercise; Female; Humans; Hypoxia; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Photic Stimulation; Prostaglandin Antagonists; Retinal Artery; Vasodilation; Young Adult | 2015 |
Preserved Pressure Autoregulation but Disturbed Cyclo-Oxygenase and Nitric Oxide Effects on Retinal Arterioles during Acute Hypoxia in Diabetic Patients without Retinopathy.
Topics: Adult; Arterial Pressure; Arterioles; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Diclofenac; Endothelium-Dependent Relaxing Factors; Female; Homeostasis; Humans; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Prospective Studies; Retinal Artery; Vasodilation | 2016 |