Page last updated: 2024-09-03

omega-n-methylarginine and citrulline

omega-n-methylarginine has been researched along with citrulline in 89 studies

Compound Research Comparison

Studies (omega-n-methylarginine)	Trials (omega-n-methylarginine)	Recent Studies (post-2010) (omega-n-methylarginine)	Studies (citrulline)	Trials (citrulline)	Recent Studies (post-2010) (citrulline)
4,411	344	336	4,572	195	1,537

Research

Studies (89)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.25)	18.7374
1990's	63 (70.79)	18.2507
2000's	17 (19.10)	29.6817
2010's	7 (7.87)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fast, W; Hu, S; Monzingo, AF; Robertus, JD; Schaller, TH; Wang, Y	1
Ramwell, PW; Thomas, G	1
Böhme, E; Heinzel, B; John, M; Klatt, P; Mayer, B	1
Bassetti, S; Keist, R; Keller, R; Klauser, S; Mülsch, A	1
Datto, GA; Wolff, DJ	1
Chen, PY; Sanders, PW	1
Frölich, JC; Haake, G; Kastner, S; Klanke, B; Radermacher, J; Schurek, HJ; Stolte, HF	1
Billiar, TR; Curran, RD; Hoffman, RA; Langrehr, JM; Simmons, RL	1
Hibbs, JB; Lancaster, JR	1
Baeblich, SE; Böhme, E; Klein, MM; Schmidt, HH; Zernikow, BC	1
Adams, LB; Hibbs, JB; Krahenbuhl, JL; Taintor, RR	1
Harris, HJ; Hecker, M; Katsura, M; Mitchell, JA; Thiemermann, C; Vane, JR	1
Bredt, DS; Snyder, SH	1
Billiar, TR; Curran, RD; Hofmann, K; Simmons, RL; West, MA	1
Hida, W; Kikuchi, Y; Miki, H; Mizusawa, A; Ogawa, H; Shirato, K	1
Campbell, EB; Gross, SS; Hattori, Y	1
Baydoun, AR; Mann, GE	1
Araki, N; Fukuuchi, Y; Komatsumoto, S; Ohta, K; Shibata, M; Shimazu, K	1
Kunz, D; Mühl, H; Pfeilschifter, J	1
Fickling, SA; MacAllister, RJ; Vallance, P; Whitley, GS	1
Frey, C; Griffith, OW; Gross, SS; Masters, BS; McMillan, K; Narayanan, K; Spack, L	1
Ma, L; Morita, I; Murota, S	1
el-Fakahany, EE; Hu, J; Mahmoud, MI	1
Marletta, MA; Olken, NM; Osawa, Y	1
Abu-Soud, HM; Clark, P; Feldman, PL; Stuehr, DJ	1
Momose, K; Nomoto, M; Shimizu, S; Yamamoto, T	1
Beanum, VC; Garner, HR; Gibson, JD; Mayeux, PR	1
Barjavel, MJ; Bhargava, HN	1
Mühl, H; Pfeilschifter, J	1
Conte, A; Ottaviani, E	1
Decking, UK; Flesche, CW; Gödecke, A; Schrader, J	1
Hey, C; Racké, K; Wessler, I	1
Belia, S; Chiorean, M; Corinaldesi, R; De Giorgio, R; Distrutti, E; Fano, G; Fiorucci, S; Morelli, A; Santucci, L; Stanghellini, V	1
Bogle, RG; MacAllister, RJ; Vallance, P; Whitley, GS	1
Griffith, OW; Joly, GA; Kilbourn, RG; Narayanan, K	1
Chang, K; Corbett, JA; Currie, MG; Hasan, KS; McDaniel, ML; Misko, TP; Moore, WM; Petrash, JM; Smith, SR; Tilton, RG	1
Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML	1
Feldman, PL; Griffith, OW; Hong, H; Stuehr, DJ	1
Blum, G; Caramelo, C; Casado, S; Gallego, MJ; López Farré, A; Montón, M; Riesco, A	1
Marletta, MA; Olken, NM	1
Ichikawa, M; Jimbo, M; Kumagai, K; Murakami, M; Ryuzaki, M; Saruta, T; Suzuki, H	1
Bindoni, M; Cardile, V; Jiang, X; Renis, M	1
Griffith, OW; Kilbourn, RG	1
Masters, BS; McMillan, K; Salerno, JC	1
Miethke, P; Morgan, IG; Wellard, JW	1
Anzai, M; Shibuya, M; Suzuki, Y; Takayasu, M; Tanazawa, T; Tsugane, S	1
Bentura, ML; Cueto, M; Golvano, MP; Hernández-Perera, O; Lamas, S; Martín, R; Rodrigo, J	1
Hodson, H; Kimoto, M; MacAllister, RJ; Ogawa, T; Parry, H; Russell, RJ; Vallance, P; Whitley, GS	1
García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA	1
Arese, M; Bosc, JY; Bussolino, F; Canaud, B; Cristol, JP; Strasly, M; Tetta, C; Wratten, ML	1
Kobayashi, K; Maruyama, I; Nakagawa, S; Nakata, M; Yada, T	1
Danner, RL; Rafferty, SP; Wang, S; Wesley, RA; Yan, L	1
DeGeorge, GL; Heck, DE; Laskin, JD	1
Berón de Astrada, M; Chaud, MA; Franchi, AM; Gimeno, MF	1
Alloatti, G; Bosia, A; Costamagna, C; Gallo, MP; Ghigo, D; Levi, RC; Penna, C	1
Boer, P; Haverkamp, J; Heerma, W; Koomans, HA; Lagerwerf, FM; Rabelink, TJ; van Rijn, HJ; Versluis, C; Wever, RM	1
Eguchi, D; Ishida, M; Kawasaki, K; Komori, K; Okazaki, J; Sugimachi, K	1
Carmo, A; Carvalho, AP; Cruz, MT; Lopes, MC	1
Adolfsson, J; Bergerheim, US; Brundin, L; Jansson, OT; Morcos, E; Wiklund, NP	1
Ameshima, S; Demura, Y; Ishizaki, T; Matsukawa, S; Miyamori, I; Okamura, S	1
Berón de Astrada, M; Boquet, M; Cebral, E; Gimeno, MA; Motta, A	1
Aldieri, E; Bosia, A; Costamagna, C; Ghigo, D; Massobrio, M; Pellerey, O; Revelli, A; Soldati, G	1
Weiske, J; Wiesner, A	1
Coaxum, SD; Maleque, MA; McDuffie, JE	1
Gotoh, T; Iwase, K; Koshiyama, Y; Mori, M; Nagasaki, A; Negi, A; Takeshima, H; Takiguchi, M; Yamamoto, K; Zhang, WY	1
Cholewa, B; Mattson, DL; Wu, F	1
Holt, PG; Sly, PD; Tulić, MK; Wale, JL	1
Boer, P; Dijkhorst-Oei, LT; Koomans, HA; Rabelink, TJ	1
Knowles, RG; Salter, M	1
Gourdon, I; Guérin, MC; Roch, P; Torreilles, J	1
Balaban, RS; French, S; Giulivi, C	1
Conrad, KP; Davis, AK; Novak, J; Powers, RW	1
Ferro, A; Jackson, G; Ji, Y; O'Kane, PD; Queen, LR; Reebye, V; Stratton, P	1
Grosser, N; Schröder, H	1
Nakata, M; Yada, T	1
Chinje, EC; Goodyer, CL; Jaffar, M; Stratford, IJ; Threadgill, MD	1
Antunes-Rodrigues, J; Cunha, FQ; Elias, LL; Giusti-Paiva, A; Gomes, DA; Reis, WL; Ventura, RR	1
Cardounel, AJ; Xia, Y; Zweier, JL	1
Costello, AL; Fast, W; Stone, EM; Tierney, DL	1
Brett, SE; Casadei, B; Chowienczyk, PJ; Seddon, MD; Shah, AM	1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z	1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z	1
Jung, CS	1
Akahoshi, A; Kitamatsu, M; Ohtsuki, T; Sisido, M; Suzue, Y	1
Brett, S; Casadei, B; Chowienczyk, P; Melikian, N; Seddon, M; Shabeeh, H; Shah, AM	1
Casadei, B; Chowienczyk, P; Dworakowski, R; Melikian, N; Shabeeh, H; Shah, AM	1
Bos, GM; Briedé, JJ; Germeraad, WT; Huijskens, MJ; Koller, N; Schnijderberg, MC; Senden-Gijsbers, BL; Walczak, M	1
Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E	1
Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E	1

Trials

3 trial(s) available for omega-n-methylarginine and citrulline

Article	Year
Removal of constitutive and inducible nitric oxide synthase-active compounds in a modified hemodiafiltration with on-line production of substitution fluid: the contribution of convection and diffusion. The International journal of artificial organs, 1996, Volume: 19, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Animals; Cell Line; Citrulline; Convection; Diffusion; Endothelium, Vascular; Enzyme Induction; Extracellular Space; Hemodiafiltration; Humans; Kidney Failure, Chronic; Macrophages; Male; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Online Systems; Plasma; Uremia	1996
Nitric oxide synthesis inhibition does not impair water immersion-induced renal vasodilation in humans. Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:7 Topics: Adult; Arginine; Blood Pressure; Citrulline; Diuresis; Enzyme Inhibitors; Hormones; Humans; Immersion; Male; Natriuresis; Nitric Oxide; omega-N-Methylarginine; Renal Circulation; Vascular Resistance; Vasodilation; Water	2000
Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment. Cardiovascular research, 2003, Jul-01, Volume: 59, Issue:1 Topics: Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Aspirin; Blood Platelets; Citrulline; Cyclooxygenase Inhibitors; Drug Administration Schedule; Female; Humans; Indomethacin; Isoproterenol; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors	2003

Other Studies

86 other study(ies) available for omega-n-methylarginine and citrulline

Article	Year
Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry, 2009, Sep-15, Volume: 48, Issue:36 Topics: Amidines; Amidohydrolases; Crystallography, X-Ray; Drug Delivery Systems; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type I; Ornithine; Recombinant Proteins; Substrate Specificity; Thiourea	2009
Interaction of non-arginine compounds with the endothelium-derived relaxing factor inhibitor, NG-monomethyl L-arginine. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: Amiloride; Animals; Aorta; Arginine; Bucladesine; Citrulline; Drug Interactions; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasodilation; Vasodilator Agents	1992
Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. The Biochemical journal, 1992, Feb-01, Volume: 281 ( Pt 3) Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Calcium; Calmodulin; Citrulline; Hydrogen Peroxide; NADP; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine	1992
Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages. Biochemical and biophysical research communications, 1992, May-15, Volume: 184, Issue:3 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bone Marrow; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Drug Resistance; Enterococcus faecalis; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Moraxella catarrhalis; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Onium Compounds; Peptidoglycan; Phagocytes; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha	1992
Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells. The Biochemical journal, 1992, Jul-01, Volume: 285 ( Pt 1) Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoradiography; Biopterins; Blotting, Western; Brain; Calmodulin; Cattle; Cells, Cultured; Chromatography, DEAE-Cellulose; Citrulline; Enzyme Activation; Kinetics; NADH Dehydrogenase; Nitric Oxide Synthase; Nitroarginine; Nitroblue Tetrazolium; omega-N-Methylarginine; Pituitary Gland	1992
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats. The Journal of clinical investigation, 1991, Volume: 88, Issue:5 Topics: Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Glomerular Filtration Rate; Hypertension; Nitric Oxide; omega-N-Methylarginine; Rats; Sodium Chloride	1991
Effect of arginine depletion on glomerular and tubular kidney function: studies in isolated perfused rat kidneys. The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2 Topics: Animals; Arginine; Body Water; Citrulline; Glomerular Filtration Rate; Glucose; In Vitro Techniques; Kidney; Kidney Glomerulus; Kidney Tubules; Male; omega-N-Methylarginine; Ornithine; Perfusion; Rats; Rats, Inbred Strains; Sodium; Time Factors; Urine	1991
Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine. Journal of immunology (Baltimore, Md. : 1950), 1990, Oct-01, Volume: 145, Issue:7 Topics: Animals; Arginine; Citrulline; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Immune Tolerance; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophages; Mice; Nitrates; omega-N-Methylarginine; Phytohemagglutinins; Rats; T-Lymphocytes; T-Lymphocytes, Cytotoxic	1990
EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:3 Topics: Animals; Arginine; Cells, Cultured; Citrulline; Electron Spin Resonance Spectroscopy; Female; Iron; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mycobacterium bovis; Nitrogen; Nitrogen Oxides; omega-N-Methylarginine; Sulfur; Tuberculosis	1990
L-arginine and arginine analogues: effects on isolated blood vessels and cultured endothelial cells. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Guanethidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Swine	1990
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine. Journal of immunology (Baltimore, Md. : 1950), 1990, Apr-01, Volume: 144, Issue:7 Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma	1990
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine. Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3 Topics: Acetylcholine; Animals; Aorta; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rabbits	1990
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:22 Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats	1989
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine. Archives of surgery (Chicago, Ill. : 1960), 1989, Volume: 124, Issue:12 Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains	1989
Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia. The Journal of physiology, 1995, Jul-15, Volume: 486 ( Pt 2) Topics: Animals; Arginine; Citrulline; Dizocilpine Maleate; Drug Combinations; Enzyme Inhibitors; Glutamic Acid; Hypercapnia; Hypoxia; Male; Microinjections; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Respiration; Solitary Nucleus	1995
Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis. The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13 Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Argininosuccinate Synthase; Base Sequence; Cells, Cultured; Citrulline; Cycloheximide; Cytosol; Dactinomycin; Dexamethasone; DNA Primers; Enzyme Induction; Interferon-gamma; Kinetics; Lipopolysaccharides; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Recombinant Proteins; RNA, Messenger	1994
Selective targeting of nitric oxide synthase inhibitors to system y+ in activated macrophages. Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2 Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Canavanine; Carrier Proteins; Cell Line; Citrulline; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Receptors, Virus	1994
Modification of striatal arginine and citrulline metabolism by nitric oxide synthase inhibitors. Neuroreport, 1994, Mar-21, Volume: 5, Issue:7 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Corpus Striatum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley	1994
Expression of nitric oxide synthase in rat glomerular mesangial cells mediated by cyclic AMP. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Oxidoreductases; Animals; Antimetabolites; Arginine; Blotting, Northern; Cells, Cultured; Citrulline; Cyclic AMP; Cytosol; Enzyme Activation; Glomerular Mesangium; Interleukin-1; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation	1994
Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Amino Acid Oxidoreductases; Arginase; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Endothelium, Vascular; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Umbilical Veins	1994
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. The Journal of biological chemistry, 1994, Oct-21, Volume: 269, Issue:42 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Citrulline; Cytochrome c Group; Heme; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thiourea	1994
Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra. Neuroscience letters, 1994, Jun-20, Volume: 174, Issue:2 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Citrulline; Cyclic GMP; Histocytochemistry; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats	1994
Polyamines inhibit nitric oxide synthase in rat cerebellum. Neuroscience letters, 1994, Jul-04, Volume: 175, Issue:1-2 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium	1994
Characterization of the inactivation of nitric oxide synthase by NG-methyl-L-arginine: evidence for heme loss. Biochemistry, 1994, Dec-13, Volume: 33, Issue:49 Topics: Amino Acid Oxidoreductases; Arginine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Citrulline; Cytochrome P-450 Enzyme System; Enzyme Stability; Heme; Hemeproteins; Hydrogen Peroxide; Isotope Labeling; Nitric Oxide Synthase; omega-N-Methylarginine; Solubility; Spectrophotometry; Tritium	1994
Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction. The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cells, Cultured; Citrulline; Cloning, Molecular; Electrons; Heme; Humans; Iron; Kinetics; NADP; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Thiourea	1994
Reduction by NG-nitro-L-arginine of H2O2-induced endothelial cell injury. British journal of pharmacology, 1994, Volume: 113, Issue:2 Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cattle; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Citrulline; Endothelium, Vascular; Hydrogen Peroxide; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine	1994
Effect of lipopolysaccharide on nitric oxide synthase activity in rat proximal tubules. Biochemical pharmacology, 1995, Jan-06, Volume: 49, Issue:1 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Kidney Tubules, Proximal; Kinetics; Lipopolysaccharides; Male; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley	1995
Effect of opioid receptor agonists on nitric oxide synthase activity in rat cerebral cortex homogenate. Neuroscience letters, 1994, Nov-07, Volume: 181, Issue:1-2 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Citrulline; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Opioid	1994
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells. The Journal of clinical investigation, 1995, Volume: 95, Issue:4 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Cell Nucleus; Citrulline; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic	1995
Nitric oxide synthase activity in molluscan hemocytes. FEBS letters, 1995, May-29, Volume: 365, Issue:2-3 Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails	1995
Endotoxin-induced contractile dysfunction in guinea pig hearts is not mediated by nitric oxide. The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2 Topics: Adenine Nucleotides; Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Chromatography, High Pressure Liquid; Citrulline; Coronary Circulation; Endotoxins; Energy Metabolism; Enzyme Induction; Guinea Pigs; Heart; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphocreatine; Vascular Resistance; Ventricular Function, Left	1995
Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:6 Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Sprague-Dawley	1995
Nitric oxide modulates pepsinogen secretion induced by calcium-mediated agonist in guinea pig gastric chief cells. Gastroenterology, 1995, Volume: 109, Issue:4 Topics: Animals; Arginine; Calcium; Calmodulin; Carbachol; Cells, Cultured; Cholecystokinin; Citrulline; Cyclic GMP; Egtazic Acid; Gastric Mucosa; Gastrins; Guinea Pigs; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pepsinogens; Terpenes; Thapsigargin	1995
Induction of NG-monomethyl-L-arginine uptake: a mechanism for differential inhibition of NO synthases? The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 1 Topics: Animals; Arginine; Biological Transport; Cell Line; Citrulline; Cytokines; Endothelium, Vascular; Endotoxins; Humans; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Time Factors	1995
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta. British journal of pharmacology, 1995, Volume: 115, Issue:3 Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents	1995
Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation. Diabetes, 1993, Volume: 42, Issue:2 Topics: Aldehyde Reductase; Amino Acid Oxidoreductases; Animals; Arginine; Benzothiazoles; Blood Pressure; Body Weight; Capillary Permeability; Citrulline; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Imidazoles; Imidazolidines; Inositol; Iodine Radioisotopes; Male; Methylguanidine; Naphthalenes; Nitric Oxide Synthase; omega-N-Methylarginine; Phthalazines; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Serum Albumin, Bovine; Sorbitol; Thiazoles; Uvea	1993
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside. Diabetologia, 1993, Volume: 36, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides	1993
Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation. Journal of medicinal chemistry, 1993, Feb-19, Volume: 36, Issue:4 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Humans; Hydroxylation; Kinetics; Macrophages; Mice; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Recombinant Proteins	1993
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes. The Biochemical journal, 1993, Jun-15, Volume: 292 ( Pt 3) Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine	1993
NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase. Biochemistry, 1993, Sep-21, Volume: 32, Issue:37 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Citrulline; Formaldehyde; Hydrogen Peroxide; In Vitro Techniques; Macrophages; Mice; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Structure-Activity Relationship; Superoxide Dismutase	1993
Nitric oxide increases renal blood flow by interacting with the sympathetic nervous system. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:2 Topics: Animals; Arginine; Citrulline; Female; Kidney; Nitric Oxide; omega-N-Methylarginine; Rabbits; Renal Circulation; Sympathetic Nervous System	1994
Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero- 3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytes. Brain research, 1996, Apr-09, Volume: 715, Issue:1-2 Topics: Animals; Antineoplastic Agents; Astrocytes; Azepines; Cells, Cultured; Citrulline; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stimulation, Chemical; Thienopyridines; Triazoles	1996
Nitric oxide synthase inhibitors: amino acids. Methods in enzymology, 1996, Volume: 268 Topics: Amino Acids; Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rodentia; Structure-Activity Relationship; Thiourea	1996
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site. Biochemistry, 1996, Sep-10, Volume: 35, Issue:36 Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats	1996
Neural barriers affect the action of nitric oxide synthase inhibitors in the intact chicken retina. Neuroscience letters, 1995, Dec-01, Volume: 201, Issue:1 Topics: Animals; Arginine; Blood-Retinal Barrier; Chickens; Citrulline; Enzyme Inhibitors; In Vitro Techniques; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Pigment Epithelium of Eye; Retina	1995
Vasodilation by intrathecal lipopolysaccharide of the cerebral arteries after subarachnoid haemorrhage in dogs. Acta neurochirurgica, 1996, Volume: 138, Issue:3 Topics: Analysis of Variance; Angiography; Animals; Arginine; Basilar Artery; Bradykinin; Citrulline; Cytokines; Dogs; Enzyme Inhibitors; Female; Injections, Spinal; Lipopolysaccharides; Male; Microscopy, Electron; Nitric Oxide Synthase; omega-N-Methylarginine; Subarachnoid Hemorrhage; Vasoconstrictor Agents; Vasodilation; Vasopressins	1996
Presence of nitric oxide synthase activity in roots and nodules of Lupinus albus. FEBS letters, 1996, Dec-02, Volume: 398, Issue:2-3 Topics: Arginine; Citrulline; Enzyme Inhibitors; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plant Roots; Plants; Rhizobiaceae	1996
Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase. British journal of pharmacology, 1996, Volume: 119, Issue:8 Topics: Amidohydrolases; Aminobutyrates; Animals; Chromatography, High Pressure Liquid; Citrulline; Enzyme Inhibitors; Female; Guanidines; Humans; Hydrolases; Immunoblotting; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pregnancy; Rats; Rats, Inbred WKY; Umbilical Veins	1996
Bacterial infection induces nitric oxide synthase in human neutrophils. The Journal of clinical investigation, 1997, Jan-01, Volume: 99, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections	1997
Citrulline-argininosuccinate-arginine cycle coupled to Ca2+-signaling in rat pancreatic beta-cells. Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3 Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Calcium; Cells, Cultured; Citrulline; Cytosol; Immunohistochemistry; Insulinoma; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured	1997
Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells. Blood, 1997, Aug-01, Volume: 90, Issue:3 Topics: Animals; Arginine; Cell Differentiation; Citrulline; Cyclic GMP; DNA, Complementary; Enzyme Induction; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Recombinant Fusion Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1997
Arginine metabolism in keratinocytes and macrophages during nitric oxide biosynthesis: multiple modes of action of nitric oxide synthase inhibitors. Biochemical pharmacology, 1997, Jul-01, Volume: 54, Issue:1 Topics: Animals; Arginine; Cell Line; Citrulline; Dose-Response Relationship, Drug; Guanidines; Interferon-gamma; Keratinocytes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured	1997
Nitric oxide mediates platelet-activating factor stimulatory action on uterine prostaglandin production. Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:1 Topics: Animals; Arachidonic Acid; Citrulline; Cyclooxygenase Inhibitors; Dinoprostone; Embryo Implantation; Enzyme Inhibitors; Female; Gestational Age; Indomethacin; Isometric Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Pregnancy; Prostaglandins; Rats; Rats, Wistar; Uterus	1998
Modulation of guinea-pig cardiac L-type calcium current by nitric oxide synthase inhibitors. The Journal of physiology, 1998, Feb-01, Volume: 506 ( Pt 3) Topics: Animals; Blotting, Western; Calcium Channels; Carbachol; Citrulline; Electrophysiology; Enzyme Inhibitors; Female; Guanosine Diphosphate; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Male; Membrane Potentials; Muscarinic Antagonists; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Patch-Clamp Techniques; Thionucleotides	1998
Assessment of nitric oxide production by measurement of [15N]citrulline enrichment in human plasma using high-performance liquid chromatography-mass spectrometry. Analytical biochemistry, 1998, Mar-01, Volume: 257, Issue:1 Topics: Chromatography, High Pressure Liquid; Citrulline; Enzyme Inhibitors; Humans; Mass Spectrometry; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Isotopes; omega-N-Methylarginine	1998
L-arginine inhibits smooth muscle cell proliferation of vein graft intimal thickness in hypercholesterolemic rabbits. Cardiovascular research, 1997, Volume: 36, Issue:3 Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Bromodeoxyuridine; Cell Division; Citrulline; Graft Rejection; Hypercholesterolemia; In Vitro Techniques; Jugular Veins; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rabbits; Tunica Intima	1997
Calcium-dependent nitric oxide synthase activity in rat thymocytes. Biochemical and biophysical research communications, 1998, Jul-09, Volume: 248, Issue:1 Topics: Animals; Arginine; Calcium; CD2 Antigens; Citrulline; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland	1998
Nitric oxide synthase activity in human renal cell carcinoma. The Journal of urology, 1998, Volume: 160, Issue:2 Topics: Analysis of Variance; Anticarcinogenic Agents; Arginine; Calcium; Carcinogens; Carcinoma, Renal Cell; Cell Division; Cells, Cultured; Citrulline; DNA; Enzyme Inhibitors; Humans; Interleukin-2; Kidney Neoplasms; Kidney Tubules, Proximal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Thymidine; Tumor Cells, Cultured	1998
The activation of eNOS by copper ion (Cu2+) in human pulmonary arterial endothelial cells (HPAEC). Free radical biology & medicine, 1998, Volume: 25, Issue:3 Topics: Arginine; Calcium; Cations, Divalent; Cells, Cultured; Citrulline; Copper; Edetic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulmonary Artery	1998
Relationship between mouse uterine contractility, nitric oxide and prostaglandin production in early pregnancy. Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 59, Issue:3 Topics: Animals; Arginine; Citrulline; Dinoprost; Enzyme Inhibitors; Female; Mice; Mice, Inbred Strains; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Uterus	1998
Follicular fluid proteins stimulate nitric oxide (NO) synthesis in human sperm: a possible role for NO in acrosomal reaction. Journal of cellular physiology, 1999, Volume: 178, Issue:1 Topics: Acrosome Reaction; Body Fluids; Canavanine; Citrulline; Enzyme Inhibitors; Female; Fertilization; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ovarian Follicle; Spermatozoa	1999
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line. Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:2 Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase	1999
5-hydroxytryptamine evokes endothelial nitric oxide synthase activation in bovine aortic endothelial cell cultures. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 221, Issue:4 Topics: Animals; Aorta; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Methiothepin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pertussis Toxin; Propanolamines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Virulence Factors, Bordetella	1999
Expression of citrulline-nitric oxide cycle in lipopolysaccharide and cytokine-stimulated rat astroglioma C6 cells. Brain research, 1999, Dec-04, Volume: 849, Issue:1-2 Topics: Animals; Arginine; Astrocytoma; Citrulline; Cytokines; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Interferon-gamma; Kinetics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1999
Characterization of L-arginine transporters in rat renal inner medullary collecting duct. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:6 Topics: Amino Acid Transport Systems; Animals; Arginine; beta-Alanine; Biological Transport; Carrier Proteins; Cations; Citrulline; Enzyme Inhibitors; Gene Expression; Homeostasis; Kidney Medulla; Kidney Tubules, Collecting; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity; Tritium; Water-Electrolyte Balance	2000
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model. The European respiratory journal, 2000, Volume: 15, Issue:5 Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea	2000
Measurement of NOS activity by conversion of radiolabeled arginine to citrulline using ion-exchange separation. Methods in molecular biology (Clifton, N.J.), 1998, Volume: 100 Topics: Animals; Arginine; Carbon Radioisotopes; Cell Fractionation; Chromatography, Ion Exchange; Citrulline; Enzyme Inhibitors; Nitric Oxide Synthase; omega-N-Methylarginine; Radioisotope Dilution Technique; Tritium	1998
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis. Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:1 Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides	2001
Nitric oxide synthase in porcine heart mitochondria: evidence for low physiological activity. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6 Topics: Animals; Arginine; Cell Respiration; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Mitochondria, Heart; Mitochondria, Liver; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Phosphorylation; Oxygen Consumption; Swine	2001
Citrulline is not the major product using the standard "NOS activity" assay on renal cortical homogenates. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:1 Topics: Animals; Antioxidants; Arginine; Biopterins; Calcium; Carbon Radioisotopes; Chelating Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Citrulline; Egtazic Acid; Enzyme Inhibitors; Female; Guanidines; Humans; Kidney Cortex; Male; Mice; Mice, Inbred Strains; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Placenta; Rats; Rats, Long-Evans; Tritium	2002
Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway. Arteriosclerosis, thrombosis, and vascular biology, 2003, Aug-01, Volume: 23, Issue:8 Topics: Animals; Aspirin; Cattle; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic N-Oxides; Cytoprotection; Diclofenac; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrogen Peroxide; Imidazoles; Indomethacin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine	2003
Endocrinology: nitric oxide-mediated insulin secretion in response to citrulline in islet beta-cells. Pancreas, 2003, Volume: 27, Issue:3 Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Citrulline; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Wistar	2003
Time-dependence and preliminary SAR studies in inhibition of nitric oxide synthase isoforms by homologues of thiocitrulline. Bioorganic & medicinal chemistry letters, 2003, Nov-03, Volume: 13, Issue:21 Topics: Animals; Citrulline; Enzyme Inhibitors; Humans; Indicators and Reagents; Isoenzymes; Kinetics; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thiourea	2003
The role of carbon monoxide and nitric oxide in hyperosmolality-induced atrial natriuretic peptide release by hypothalamus in vitro. Brain research, 2004, Jul-30, Volume: 1016, Issue:1 Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Carbon Monoxide; Citrulline; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hemoglobins; Hypothalamus; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Osmolar Concentration; Potassium Chloride; Rats	2004
Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin. The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9 Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Humans; Magnetics; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Spin Trapping; Superoxides; Time Factors; Transfection	2005
Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa. Biochemistry, 2006, May-02, Volume: 45, Issue:17 Topics: Amidohydrolases; Binding Sites; Citrulline; Cobalt; Cysteine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Lysine; Mass Spectrometry; Models, Chemical; omega-N-Methylarginine; Protons; Pseudomonas aeruginosa; Spectrophotometry, Ultraviolet; Spectrum Analysis; Thiourea; X-Rays; Zinc	2006
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo. Circulation, 2008, Apr-15, Volume: 117, Issue:15 Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Citrulline; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stress, Psychological; Thiourea; Vasodilation; Vasomotor System	2008
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death. British journal of haematology, 2009, Volume: 145, Issue:4 Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate	2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9 Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors	2009
Nitric oxide synthase inhibitors and cerebral vasospasm. Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 1 Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; S-Adenosylmethionine; Vasospasm, Intracranial	2011
Site-specific incorporation of arginine analogs into proteins using arginyl-tRNA synthetase. Biochemical and biophysical research communications, 2011, Oct-28, Volume: 414, Issue:3 Topics: Amino Acid Sequence; Aminoacylation; Arginine; Arginine-tRNA Ligase; Catalysis; Citrulline; Homoarginine; Methylation; Molecular Sequence Data; omega-N-Methylarginine; Protein Biosynthesis	2011
Sympathetic activation increases NO release from eNOS but neither eNOS nor nNOS play an essential role in exercise hyperemia in the human forearm. American journal of physiology. Heart and circulatory physiology, 2013, Volume: 304, Issue:9 Topics: Adult; Blood Pressure; Citrulline; Forearm; Hand Strength; Humans; Hyperemia; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Physical Exertion; Regional Blood Flow; Sympathetic Nervous System; Thiourea; Vasoconstriction	2013
Differential role of endothelial versus neuronal nitric oxide synthase in the regulation of coronary blood flow during pacing-induced increases in cardiac workload. American journal of physiology. Heart and circulatory physiology, 2013, Volume: 304, Issue:9 Topics: Blood Pressure; Citrulline; Coronary Circulation; Coronary Vessels; Female; Heart Rate; Humans; Male; Middle Aged; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Thiourea; Vasodilation	2013
Technical advance: ascorbic acid induces development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells. Journal of leukocyte biology, 2014, Volume: 96, Issue:6 Topics: Antigens, Differentiation, T-Lymphocyte; Antioxidants; Ascorbic Acid; CD4 Antigens; CD8 Antigens; Cell Division; Cells, Cultured; Citrulline; Coculture Techniques; Filgrastim; Gene Expression Profiling; Gene Rearrangement, T-Lymphocyte; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Immunomagnetic Separation; Integrins; Lymphopoiesis; Nitric Oxide; omega-N-Methylarginine; Primary Cell Culture; Receptors, Chemokine; Recombinant Proteins; Stromal Cells; T-Lymphocyte Subsets	2014
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study. The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6 Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry	2017
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial. Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:2 Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors	2019