Compounds > omega-n-methylarginine
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omega-n-methylarginine and captopril

omega-n-methylarginine has been researched along with captopril in 10 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)		Trials
(omega-n-methylarginine)		Recent Studies (post-2010)
(omega-n-methylarginine)		Studies
(captopril)		Trials
(captopril)		Recent Studies (post-2010) (captopril)
4,41134433610,3201,514890

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)captopril (IC50)
Leukotriene A-4 hydrolaseHomo sapiens (human)3.6
Angiotensin-converting enzyme Homo sapiens (human)0.084
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.0173
Succinyl-diaminopimelate desuccinylaseHaemophilus influenzae Rd KW203.3
Angiotensin-converting enzymeRattus norvegicus (Norway rat)0.1004
Beta-lactamase Pseudomonas aeruginosa5
Angiotensin-converting enzyme 2 Homo sapiens (human)0.011
Beta-lactamase class B VIM-2 Pseudomonas aeruginosa3.5

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (50.00)18.2507
2000's4 (40.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
de Graeff, PA; de Leeuw, MJ; Scholtens, E; van Gilst, WH; Wesseling, H1
Cachofeiro, V; Nasjletti, A; Sakakibara, T1
Bozhko, AP; Solodkov, AP1
Aikawa, J; Akatsuka, N; Fukazawa, M; Hara, K; Ishikawa, M; Moroi, M; Namiki, A; Yamaguchi, T1
Craven, PA; DeRubertis, FR; Felder, J; Phillips, S; Studer, RK1
MacCarthy, PA; Shah, AM1
Buikema, H; Crijns, HJ; de Zeeuw, D; Monnink, SH; Tio, RA; van Gilst, WH1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1
Brouwers, S; Dupont, AG; Massie, A; Smolders, I1

Trials

1 trial(s) available for omega-n-methylarginine and captopril

ArticleYear
Converting enzyme inhibitors and the role of the sulfhydryl group in the potentiation of exo- and endogenous nitrovasodilators.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Bradykinin; Captopril; Coronary Circulation; Cysteine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Nitro Compounds; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasodilator Agents

1991

Other Studies

9 other study(ies) available for omega-n-methylarginine and captopril

ArticleYear
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
Kinins, nitric oxide, and the hypotensive effect of captopril and ramiprilat in hypertension.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Captopril; Hypertension; Imidazoles; Kinins; Losartan; Male; Nitric Oxide; omega-N-Methylarginine; Pyrroles; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles

1992
[Effect of endogenous metabolites on autoregulation and dilational reserve of coronary vessels].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:5

    Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Captopril; Coronary Circulation; Coronary Vessels; Eicosanoids; Female; In Vitro Techniques; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Vasodilation; Verapamil

1993
Endothelium-dependent relaxation by angiotensin-converting enzyme inhibitors in canine femoral arteries.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Aspirin; Captopril; Dinoprost; Dipeptides; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Indans; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxyhemoglobins; Superoxide Dismutase

1994
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells.
    Diabetes, 1997, Volume: 46, Issue:4

    Topics: Animals; Captopril; Cattle; Cells, Cultured; Coculture Techniques; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glomerular Mesangium; Glucose; Indoles; Maleimides; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Penicillamine; Proline; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transforming Growth Factor beta; Tritium

1997
Impaired endothelium-dependent regulation of ventricular relaxation in pressure-overload cardiac hypertrophy.
    Circulation, 2000, Apr-18, Volume: 101, Issue:15

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Endothelium, Vascular; Guinea Pigs; Hypertrophy, Left Ventricular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Substance P; Vasodilator Agents

2000
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Calcimycin; Captopril; Endothelium, Vascular; Heart Diseases; In Vitro Techniques; Lisinopril; Male; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Sodium Nitrite; Sulfhydryl Compounds; Vasodilation; Vasodilator Agents

2000
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003
Angiotensin II type 2 receptor-mediated and nitric oxide-dependent renal vasodilator response to compound 21 unmasked by angiotensin-converting enzyme inhibition in spontaneously hypertensive rats in vivo.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fenoldopam; Imidazoles; Indomethacin; Kidney; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes; Vasodilation; Vasodilator Agents

2013