Page last updated: 2024-09-03

omega-n-methylarginine and capsaicin

omega-n-methylarginine has been researched along with capsaicin in 18 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(capsaicin)
Trials
(capsaicin)
Recent Studies (post-2010) (capsaicin)
4,41134433611,2386613,410

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (88.89)18.2507
2000's1 (5.56)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Connor, HE; Feniuk, W; Stubbs, CM; Waldron, GJ1
Tepperman, BL; Whittle, BJ1
Whittle, BJ1
Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF1
Lopez-Belmonte, J; Moncada, S; Whittle, BJ1
Bauer, MB; Gebhart, GF; Murphy, S1
Kobayashi, D; Okabe, E; Ozono, S; Todoki, K1
Kinoshita, M; Kume, E; Tamaki, H1
Geppetti, P; Nadel, JA; Ricciardolo, FL; Yoishihara, S; Yoshihara, S1
Bauer, MB; Gebhart, GF; Murphy, S; Simmons, ML1
Collins, P; Jiang, C1
Dempsey, DT; Grabowski, MW; Merchant, NB; Ritchie, WP; Rizzo, M1
Amerini, S; Ledda, F; Mantelli, L1
Ahluwalia, A; Vallance, P1
Lüscher, TF; Meier, B; Noll, G; Wenzel, RR; Zbinden, S1
Atwood, L; James, C; Morris, GP; Vanner, S1
Fujita, T; Kamisaki, Y; Yonehara, N1
Katsurada, K; Knuepfer, MM; Liu, X; Patel, KP; Zheng, H1

Trials

1 trial(s) available for omega-n-methylarginine and capsaicin

ArticleYear
Endothelin-1 induces vasodilation in human skin by nociceptor fibres and release of nitric oxide.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Capsaicin; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Humans; Male; Microcirculation; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Receptors, Endothelin; Skin; Vasodilation

1998

Other Studies

17 other study(ies) available for omega-n-methylarginine and capsaicin

ArticleYear
Characterization of the receptor mediating relaxation to substance P in canine middle cerebral artery: no evidence for involvement of substance P in neurogenically mediated relaxation.
    British journal of pharmacology, 1992, Volume: 105, Issue:4

    Topics: Animals; Arginine; Capsaicin; Cerebral Arteries; Dogs; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; omega-N-Methylarginine; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synaptic Transmission; Vasodilation

1992
Endogenous nitric oxide and sensory neuropeptides interact in the modulation of the rat gastric microcirculation.
    British journal of pharmacology, 1992, Volume: 105, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Indomethacin; Male; Microcirculation; Neurons, Afferent; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains

1992
Relationship between sensory neuropeptides and other local vasoactive mediators in modulating gastric mucosal integrity.
    Advances in experimental medicine and biology, 1991, Volume: 298

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Male; Microcirculation; Muscle, Smooth, Vascular; Neurons, Afferent; Neuropeptides; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Substance P; Vasodilation

1991
Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Acetamides; Adenosine Triphosphate; Animals; Arginine; Atropine; Autonomic Nervous System; Capsaicin; Chymotrypsin; Drug Interactions; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenyl Ethers; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Vasoactive Intestinal Peptide

1992
Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: Animals; Arginine; Blood Pressure; Capsaicin; Epoprostenol; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Neuropeptides; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer

1990
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
    Neuroscience, 1994, Volume: 62, Issue:2

    Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction

1994
Calcitonin gene-related peptide mediated neurogenic vasorelaxation in the isolated canine lingual artery.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:4

    Topics: Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Cromakalim; Dogs; Electric Stimulation; Female; Glyburide; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Propranolol; Pyrroles; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vasoconstriction; Vasodilator Agents

1995
Roles of prostaglandins, nitric oxide and the capsaicin-sensitive sensory nerves in gastroprotection produced by ecabet sodium.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: 16,16-Dimethylprostaglandin E2; Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arginine; Capsaicin; Dinoprostone; Diterpenes; Drug Interactions; Ethanol; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity

1995
Evidence for reduction of bradykinin-induced bronchoconstriction in guinea-pigs by release of nitric oxide.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Aerosols; Animals; Arginine; Blood Pressure; Bradykinin; Bronchoconstriction; Capillary Permeability; Capsaicin; Guinea Pigs; Hemodynamics; In Vitro Techniques; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Vagotomy; Vascular Resistance

1994
Bradykinin and capsaicin stimulate cyclic GMP production in cultured rat dorsal root ganglion neurons via a nitrosyl intermediate.
    Journal of neuroscience research, 1993, Oct-15, Volume: 36, Issue:3

    Topics: Animals; Arginine; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Capsaicin; Cells, Cultured; Cyclic GMP; Ganglia, Spinal; Guanylate Cyclase; Methylene Blue; Neurons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin

1993
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline

1994
Capsaicin-induced gastric mucosal hyperemia and protection: the role of calcitonin gene-related peptide.
    Surgery, 1994, Volume: 116, Issue:2

    Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; DNA; Gastric Mucosa; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow

1994
Nitric oxide is not involved in the effects induced by non-adrenergic non-cholinergic stimulation and calcitonin gene-related peptide in the rat mesenteric vascular bed.
    Neuropeptides, 1993, Volume: 25, Issue:1

    Topics: Acetylcholine; Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guanethidine; Mesentery; Methoxamine; Methylene Blue; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Perfusion; Rats; Tetrodotoxin; Vasodilation

1993
Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Enzyme Inhibitors; Male; Mesenteric Arteries; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Sympathetic Nervous System; Vasoconstriction

1996
Cellular pathways of mast cell- and capsaicin-sensitive nerve-evoked ileal submucosal arteriolar dilations.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Alprostadil; Animals; Arterioles; Bradykinin; Capsaicin; Cattle; Epoprostenol; Food Hypersensitivity; Guinea Pigs; Ileum; Indomethacin; Lactoglobulins; Mast Cells; Microscopy, Video; Milk; Muscle, Smooth; Neurons; omega-N-Methylarginine; Pyrilamine; Serotonin; Vasodilation

1998
Nitric oxide-induced increase of excitatory amino acid levels in the trigeminal nucleus caudalis of the rat with tactile hypersensitivity evoked by the loose-ligation of the inferior alveolar nerves.
    Journal of neurochemistry, 2004, Volume: 91, Issue:3

    Topics: Animals; Aspartic Acid; Benzoates; Capsaicin; Dental Pulp; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Hyperalgesia; Imidazoles; Injections, Subcutaneous; Ligation; Lip; Male; Mandibular Nerve; Microdialysis; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Trigeminal Nuclei

2004
Specific Afferent Renal Denervation Prevents Reduction in Neuronal Nitric Oxide Synthase Within the Paraventricular Nucleus in Rats With Chronic Heart Failure.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:3

    Topics: Afferent Pathways; Animals; Capsaicin; Chronic Disease; Denervation; Enzyme Inhibitors; Heart Failure; Kidney; Male; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Sensory System Agents; Sympathetic Nervous System

2018