Page last updated: 2024-09-03

omega-n-methylarginine and candesartan

omega-n-methylarginine has been researched along with candesartan in 5 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(candesartan)
Trials
(candesartan)
Recent Studies (post-2010) (candesartan)
4,4113443361,929412589

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)candesartan (IC50)
Epidermal growth factor receptorHomo sapiens (human)3.2769
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)5.9472
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.0652
Cytochrome P450 3A4Homo sapiens (human)9
Adenosine receptor A3Homo sapiens (human)1.2199
Cytochrome P450 2C9 Homo sapiens (human)3
Beta-3 adrenergic receptorHomo sapiens (human)4.3
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.2199
Alpha-2B adrenergic receptorHomo sapiens (human)3.843
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.0652
Thromboxane-A synthase Homo sapiens (human)3.0594
Type-1 angiotensin II receptorHomo sapiens (human)0.0405
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.2199

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T1
Ghiadoni, L; Magagna, A; Salvetti, A; Taddei, S; Virdis, A1
Drexler, H; Hornig, B; Kohler, C; Schlink, D; Tatge, H1
Fujita, N; Manabe, H; Matsumoto, N; Naito, Y; Ochiai, J; Oka, S; Takagi, T; Uemura, M; Yoshida, N; Yoshikawa, T1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1

Trials

2 trial(s) available for omega-n-methylarginine and candesartan

ArticleYear
Effect of the angiotensin II type 1 receptor blocker candesartan on endothelial function in patients with essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Acetylcholine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptides, Cyclic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents

2000
AT1-receptor antagonism improves endothelial function in coronary artery disease by a bradykinin/B2-receptor-dependent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Bradykinin; Bradykinin Receptor Antagonists; Coronary Artery Disease; Endothelium, Vascular; Enzyme Inhibitors; Humans; Infusions, Intra-Arterial; Middle Aged; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Radial Artery; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Receptors, Bradykinin; Tetrazoles

2003

Other Studies

3 other study(ies) available for omega-n-methylarginine and candesartan

ArticleYear
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
    Circulation, 1999, Feb-16, Volume: 99, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles

1999
An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Aorta; Apoptosis; Benzimidazoles; Biphenyl Compounds; Bradykinin; Caspase 3; Caspases; Cell Hypoxia; Cells, Cultured; Endothelium, Vascular; Humans; Imidazoles; Necrosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pyridines; Tetrazoles; Thiazepines

2003
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003