Page last updated: 2024-09-03

omega-n-methylarginine and arachidonic acid

omega-n-methylarginine has been researched along with arachidonic acid in 28 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(arachidonic acid)
Trials
(arachidonic acid)
Recent Studies (post-2010) (arachidonic acid)
4,41134433619,2954863,040

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)arachidonic acid (IC50)
60 kDa heat shock protein, mitochondrialHomo sapiens (human)4.5
Fatty acid-binding protein, adipocyteHomo sapiens (human)2.75
10 kDa heat shock protein, mitochondrialHomo sapiens (human)4.5
60 kDa chaperonin Escherichia coli7.3
10 kDa chaperonin Escherichia coli7.3
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.0715
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.6026

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's24 (85.71)18.2507
2000's4 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lewis, DA; Miller, VM1
Fujiwara, M; Jino, H; Kurahashi, K; Mekata, F; Shirahase, H; Usui, H1
Cocks, T; Crack, P1
D'Orleans-Juste, P; Hecker, M; Mitchell, JA; Vane, JR; Wood, EG1
De Kimpe, SJ; Nijkamp, FP; Van Heuven-Nolsen, D1
Moncada, S; Palmer, RM; Radomski, MW1
Kaley, G; Koller, A1
Boegehold, MA1
Martin, D; Nadler, JV; Peterson, CL; Thompson, MA1
Chen, LY; Lawson, DL; Mehta, JL1
Dikshit, M; Kumari, R; Seth, P; Srimal, RC1
Burkart, V; Kolb, H1
Andrews, JW; Brennan, GM; Hayes, JR; Henry, WR; Johnston, GD; McDermott, BJ; McGrath, LT; McVeigh, GE1
Ade, P; Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E1
Savla, U; Sporn, PH; Waters, CM1
Beron de Astrada, M; Chaud, MA; Franchi, AM; Gimeno, MF2
Klein, T; Pasquet, JP; Ullrich, V; Zou, MH1
Gimeno, M; González, E; Jawerbaum, A; Novaro, V; Sinner, D1
Bohrer, A; Hsu, FF; Ma, Z; Ramanadham, S; Turk, J1
Gelpi, E; Gimeno, M; Gómez, G; González, E; Jawerbaum, A; Peralta, C; Pustovrh, C; Roselló-Catafau, J; Sinner, D; Xaus, C1
Fogh-Andersen, N; Hansen, JM; Johansen, NJ; Mollerup, HM; Strandgaard, S1
Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E1
Farina, M; Franchi, A; Gimeno, M; Ogando, D; Perez Martinez, S; Ribeiro, ML1
Farina, M; Franchi, AM; Gimeno, M; Ogando, D; Ribeiro, ML1
Campos, LM; Casalino-Matsuda, SM; Goldraij, A; Linares, JA1
Finci-Yeheskel, Z; Hurwitz, A; Mayer, M; Milwidsky, A1
Cella, M; Farina, M; Franchi, A; Ribeiro, ML1

Trials

2 trial(s) available for omega-n-methylarginine and arachidonic acid

ArticleYear
Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus.
    Diabetologia, 1993, Volume: 36, Issue:1

    Topics: Acetylcholine; Arachidonic Acid; Arginine; Blood Glucose; Blood Platelets; Blood Pressure; Cell Membrane; Cholesterol; Diabetes Mellitus, Type 2; Dietary Fats; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Female; Fish Oils; Forearm; Glycated Hemoglobin; Heart Rate; Hemodynamics; Humans; Male; Membrane Lipids; Middle Aged; Nitric Oxide; Olive Oil; omega-N-Methylarginine; Plant Oils; Triglycerides; Vascular Resistance

1993
Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man.
    Journal of hypertension, 1999, Volume: 17, Issue:12 Pt 1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Blood Pressure; Body Weight; Cardiovascular Physiological Phenomena; Cyclosporine; Dinoprostone; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Reference Values; Renin; Sodium; Thromboxane B2

1999

Other Studies

26 other study(ies) available for omega-n-methylarginine and arachidonic acid

ArticleYear
Role of lipoxygenase and cytochrome P-450 in production of endothelium-derived relaxing factors in canine femoral veins.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arginine; Benzoquinones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Femoral Vein; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Piperidines; Proadifen

1992
Endothelium-dependent contraction produced by acetylcholine and relaxation produced by histamine in monkey basilar arteries.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arginine; Basilar Artery; Dinoprost; Endothelium, Vascular; Female; Histamine; In Vitro Techniques; Macaca; Male; Methylene Blue; Muscle, Smooth, Vascular; omega-N-Methylarginine; Vasoconstriction; Vasodilation

1992
Thimerosal blocks stimulated but not basal release of endothelium-derived relaxing factor (EDRF) in dog isolated coronary artery.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arginine; Arteries; Bradykinin; Calcimycin; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Thimerosal; Vasoconstrictor Agents

1992
Comparison of the release of vasoactive factors from venous and arterial bovine cultured endothelial cells.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:5

    Topics: Amino Acids; Animals; Arachidonic Acid; Arginine; Bradykinin; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelins; Endothelium, Vascular; Epoprostenol; Fluorescence; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay

1992
Bovine polymorphonuclear leukocytes increase sensitivity to noradrenaline in isolated mesenteric arteries.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arginine; Cattle; Free Radical Scavengers; In Vitro Techniques; Luminescent Measurements; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neutrophils; Norepinephrine; omega-N-Methylarginine; Radioimmunoassay; Thromboxane B2

1992
Characterization of the L-arginine:nitric oxide pathway in human platelets.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Arachidonic Acid; Arachidonic Acids; Arginine; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism; Thrombin

1990
Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation.
    Circulation research, 1990, Volume: 67, Issue:2

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arginine; Arteries; Arterioles; Blood Flow Velocity; Erythrocytes; Indomethacin; Male; Meclofenamic Acid; Microcirculation; Muscle, Smooth, Vascular; Muscles; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Regression Analysis; Vasodilation

1990
Flow-dependent arteriolar dilation in normotensive rats fed low- or high-salt diets.
    The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 2

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arginine; Arterioles; Blood Pressure; Diet, Sodium-Restricted; Male; Meclofenamic Acid; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Sodium Chloride, Dietary; Time Factors; Vasodilation

1995
Modulation of glutamate and aspartate release from slices of hippocampal area CA1 by inhibitors of arachidonic acid metabolism.
    Journal of neurochemistry, 1995, Volume: 64, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arginine; Aspartic Acid; Female; Flavanones; Flavonoids; gamma-Aminobutyric Acid; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Indomethacin; Masoprocol; omega-N-Methylarginine; Platelet Activating Factor; Potassium; Prostaglandin-Endoperoxide Synthases; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Taurine

1995
Reduction in human neutrophil superoxide anion generation by n-3 polyunsaturated fatty acids: role of cyclooxygenase products and endothelium-derived relaxing factor.
    Thrombosis research, 1994, Nov-15, Volume: 76, Issue:4

    Topics: Arachidonic Acid; Arginine; Aspirin; Depression, Chemical; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans; Indomethacin; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Respiratory Burst; Superoxides

1994
Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine.
    Blood, 1994, Oct-15, Volume: 84, Issue:8

    Topics: Animals; Arachidonic Acid; Arginine; Free Radicals; Hydroxyl Radical; Luminescent Measurements; Luminol; Male; Malondialdehyde; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate

1994
Protection of islet cells from inflammatory cell death in vitro.
    Clinical and experimental immunology, 1993, Volume: 93, Issue:2

    Topics: Animals; Arachidonic Acid; Arginine; Benzamides; Cell Death; Cells, Cultured; Cytotoxicity, Immunologic; DNA Repair; Islets of Langerhans; Macrophages; omega-N-Methylarginine; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species

1993
Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.
    FEBS letters, 1997, Aug-18, Volume: 413, Issue:2

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Microglia; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine

1997
Cyclic stretch of airway epithelium inhibits prostanoid synthesis.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Arachidonic Acid; Catalase; Cats; Cells, Cultured; Dinoprostone; Epithelial Cells; Humans; Kinetics; omega-N-Methylarginine; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins H; Stress, Mechanical; Thromboxane B2; Time Factors; Trachea

1997
Role of nitric oxide on oxytocin-evoked contractions and prostaglandin synthesis in isolated pregnant rat uterus.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 57, Issue:3

    Topics: Animals; Arachidonic Acid; Dinoprost; Enzyme Inhibitors; Female; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxytocin; Pregnancy; Prostaglandins; Rats; Rats, Wistar; Uterine Contraction; Uterus

1997
Nitric oxide mediates platelet-activating factor stimulatory action on uterine prostaglandin production.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:1

    Topics: Animals; Arachidonic Acid; Citrulline; Cyclooxygenase Inhibitors; Dinoprostone; Embryo Implantation; Enzyme Inhibitors; Female; Gestational Age; Indomethacin; Isometric Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Pregnancy; Prostaglandins; Rats; Rats, Wistar; Uterus

1998
Interleukin 1beta decreases prostacyclin synthase activity in rat mesangial cells via endogenous peroxynitrite formation.
    The Biochemical journal, 1998, Dec-01, Volume: 336 ( Pt 2)

    Topics: Animals; Antioxidants; Arachidonic Acid; Chelating Agents; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Glomerular Mesangium; Interleukin-1; Intramolecular Oxidoreductases; Nitrates; Nitric Oxide; omega-N-Methylarginine; Prostaglandin H2; Prostaglandins H; Rats; Superoxide Dismutase

1998
Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 59, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Diabetes Mellitus, Type 2; Dinoprost; Dinoprostone; Enzyme Inhibitors; Female; Gestational Age; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Placenta; Pregnancy; Pregnancy in Diabetics; Prostaglandins; Rats; Rats, Wistar; Reference Values; Thromboxane B2

1998
Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells.
    The Journal of biological chemistry, 1999, May-14, Volume: 274, Issue:20

    Topics: Animals; Arachidonic Acid; Cricetinae; Enzyme Inhibitors; Ethylmaleimide; Fatty Acids; Group VI Phospholipases A2; Insulinoma; Interleukin-1; Islets of Langerhans; Lysophosphatidylcholines; Male; Naphthalenes; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phospholipids; Propranolol; Pyrones; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured

1999
Evolution of streptozotocin-pancreatic damage in the rat: modulatory effect of endothelins on the nitridergic and prostanoid pathway.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:6

    Topics: Animals; Arachidonic Acid; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Endothelin-1; Endothelins; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Pancreas; Rats; Rats, Wistar; Spermine; Streptozocin; Thromboxane B2

1999
Different effects of reactive nitrogen intermediates on prostaglandin E2 synthesis in cultured rat microglia and RAW 264.7 cells.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Arachidonic Acid; Cell Line; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Macrophages; Mice; Microglia; Molsidomine; Monocytes; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats

1999
The effect of epidermal growth factor on prostaglandin synthesis of oestrogenized rat uterus is mediated by nitric oxide.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:6

    Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epidermal Growth Factor; Estradiol; Female; In Vitro Techniques; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Uterus

1999
IL1alpha augments prostaglandin synthesis in pregnant rat uteri by a nitric oxide mediated mechanism.
    Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 62, Issue:4

    Topics: Animals; Arachidonic Acid; Carbon Radioisotopes; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Guanidines; Interleukin-1; Interleukin-2; Nitric Oxide; Nitric Oxide Synthase; Nitrobenzenes; omega-N-Methylarginine; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Uterus

2000
Influence of insulin on the metabolism of glucose in uteri isolated from ovariectomized and non ovariectomized underfed rats.
    Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 63, Issue:6

    Topics: Amenorrhea; Animals; Arachidonic Acid; Arginine; Aspirin; Diestrus; Dose-Response Relationship, Drug; Eicosanoids; Energy Metabolism; Enzyme Inhibitors; Female; Food Deprivation; Glucose; Hemoglobins; Insulin; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Ovariectomy; Rats; Rats, Wistar; Uterus

2000
Regulation of cyclooxygenase activity and progesterone production in the rat corpus luteum by inducible nitric oxide synthase.
    Reproduction (Cambridge, England), 2002, Volume: 123, Issue:5

    Topics: Animals; Arachidonic Acid; Aspirin; Cells, Cultured; Corpus Luteum; Cyclooxygenase Inhibitors; Depression, Chemical; Enzyme Inhibitors; Female; Gonadotropins, Equine; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; omega-N-Methylarginine; Progesterone; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Rats, Inbred Strains

2002
Crosstalk between nitric oxide synthase and cyclooxygenase metabolites in the estrogenized rat uterus.
    Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 68, Issue:4

    Topics: Animals; Arachidonic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogens; Female; Hemoglobins; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Uterus

2003