Page last updated: 2024-09-03

omega-n-methylarginine and adenosine

omega-n-methylarginine has been researched along with adenosine in 63 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
4,41134433632,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's38 (60.32)18.2507
2000's22 (34.92)29.6817
2010's3 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T1
Calignano, A; Mancuso, F; Persico, P; Sorrentino, L1
Ishizaka, H; Okumura, K; Tsuchiya, T; Yamabe, H; Yasue, H2
Fujiwara, S; Fukui, M; Iwaki, T; Kanaide, H; Moriguchi, M; Natori, Y; Takeshita, I1
Gustafsson, LE; Hedqvist, P; Moncada, S; Persson, MG; Wiklund, NP1
Dai, HB; Piana, RN; Sellke, FW; Shafique, T1
Crystal, GJ; Gurevicius, J; Metwally, AA; Salem, MR; Silver, JM1
Banitt, P; Creager, MA; Lipson, DE; Rongen, GA; Smits, P; Williams, SB1
Andrews, NP; Cannon, RO; Dakak, N; Gilligan, DM; Panza, JA; Quyyumi, AA1
Chiba, Y; Goto, M; Hiramatsu, O; Kajiya, F; Kimura, A; Lu, S; Ogasawara, Y; Tachibana, H; Tsujioka, K; Yada, T1
Cutler, BS; Dobson, JG; Fenton, RA; Li, JM1
Andrews, NP; Arora, S; Cannon, RO; Dakak, N; Gilligan, DM; Husain, S; Panza, JA; Quyyumi, AA1
Hargittai, PT; Lieberman, EA; Mustafa, SJ; Olanrewaju, HA1
Chang, CH; Hsieh, HC; Hsieh, MJ; Kao, CL; Lin, PJ; Tsai, KT; Yao, PC1
Collins, P; Jiang, C1
Mehta, JL; Yang, BC1
Ilebekk, A; Kirkebøen, KA; Naess, PA; Offstad, J1
Fukuuchi, Y; Isozumi, K; Itoh, Y; Takeda, H1
Abdel-Rahman, AA; el-Mas, MM; Fahim, M; Mustafa, SJ1
Kaley, G; Koller, A; Messina, EJ; Sun, D1
Kajiyama, G; Matsuura, H; Morishima, N; Nakayama, K; Shiode, N; Yamagata, T1
Byrne, BJ; Kass, DA; Recchia, FA; Saeki, A; Senzaki, H1
Mayhan, WG1
Allen, S; Anastasiou, N; Chester, A; Paniagua, R; Yacoub, M1
Ikeda, U; Kurosaki, K; Okada, K; Saito, T; Shimada, K; Shimpo, M1
Ali, S; Metzger, WJ; Mustafa, SJ; Olanrewaju, HA1
Hirashima, O; Inobe, Y; Kawano, H; Kugiyama, K; Motoyama, T; Ogawa, H; Ohgushi, M; Soejima, H; Sugiyama, S; Yasue, H; Yoshimura, M1
Dahms, TE; Pearse, DB; Wagner, EM1
Biaggioni, I; Costa, F1
Gidday, JM; Zhu, Y1
Jan, CR; Lo, WC; Tseng, CJ; Wu, SN1
Korompai, FL; Lynch, DM; Meng, F; Yuan, YS1
Elliott, GT; Jacobson, KA; Liang, BT; Stambaugh, K1
Dankelman, J; Goto, M; Kajiya, F; Merkus, D; Spaan, JA; Vergroesen, I; Vink, H1
Hirao, H; Kajiyama, G; Kato, M; Matsuura, H; Shiode, N; Teragawa, H; Yamada, T; Yamagata, T1
Chilian, WM; Nishikawa, Y; Stepp, DW1
Castle, SF; Duffy, SJ; Harper, RW; Meredith, IT1
Du, XJ; Percy, E; Vincan, E; Woodcock, EA1
Isoda, T; Kass, DA; Pagliaro, P; Paolocci, N; Saavedra, WF; Sunagawa, G1
Epstein, N; Husain, S; Mincemoyer, R; Prasad, A; Quyyumi, AA; Schenke, W1
Pallone, TL; Silldorff, EP1
Chang, CI; Hein, TW; Kuo, L; Wang, W; Zhang, C1
Demirci, C; Reitsma, HJ; Stehouwer, CD; Tangelder, GJ; van Dam, B; van den Bos, GC; van Lambalgen, AA1
Boegehold, MA; Sauls, BA1
Arimura, K; Egashira, K; Ide, T; Machida, Y; Nakamura, R; Shimokawa, H; Takeshita, A; Tsutsui, H1
Ding, Z; Gödecke, A; Schrader, J; Ziegler, M1
Assen, YJ; Duncker, DJ; Fung, TY; Haitsma, DB; Merkus, D; Verdouw, PD1
Dennis, DM; Martynyuk, AE; Morey, TE; Rajasekaran, S1
Dinenno, FA; Joyner, MJ1
Chou, YC; Chu, JJ; Chu, Y; Chueh, HY; Lin, PJ; Liu, HP; Wu, YC1
Bonser, RS; Camici, PG; Gnecchi-Ruscone, T; Kaufmann, PA; Lüscher, TF; Rimoldi, O1
Gewirtz, H1
Anderson, TJ; Curtis, MJ; Goodhart, DM; Worthley, MI1
de Leeuw, PW; Houben, AJ; Koster, D; Kroon, AA; Postma, CT; Smits, P; van Engelshoven, JM; Wierema, TK1
Charkoudian, N; Eisenach, JH; Joyner, MJ; Martin, EA; Nicholson, WT1
Huxley, VH; Sarelius, IH; Wang, JJ1
Camici, PG; Gnecchi-Ruscone, T; Kaufmann, PA; Luscher, TF; Rimoldi, OE1
Bune, LT; González-Alonso, J; Hellsten, Y; Mortensen, SP; Pilegaard, H; Saltin, B1
Hellsten, Y; Mortensen, SP; Nyberg, M; Saltin, B; Thaning, P1
Groszmann, RJ; Mehal, WZ; Ripoll, C; Zipprich, A1
Casey, DP; Joyner, MJ; Lopez, MG; Silva, BM1
Crecelius, AR; Dinenno, FA; Hearon, CM; Kirby, BS; Larson, DG; Luckasen, GJ1

Trials

4 trial(s) available for omega-n-methylarginine and adenosine

ArticleYear
Contribution of nitric oxide to metabolic coronary vasodilation in the human heart.
    Circulation, 1995, Aug-01, Volume: 92, Issue:3

    Topics: Acetylcholine; Adenosine; Adult; Arginine; Cardiac Pacing, Artificial; Coronary Artery Disease; Coronary Circulation; Female; Humans; Male; Middle Aged; Myocardium; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Risk Factors; Vascular Resistance; Vasodilation

1995
Blunted sympathetic vasoconstriction in contracting skeletal muscle of healthy humans: is nitric oxide obligatory?
    The Journal of physiology, 2003, Nov-15, Volume: 553, Issue:Pt 1

    Topics: Adenosine; Adult; Enzyme Inhibitors; Forearm; Hand Strength; Humans; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Sympathetic Nervous System; Tyramine; Vasoconstriction; Vasodilator Agents

2003
Systemic nitric oxide synthase inhibition improves coronary flow reserve to adenosine in patients with significant stenoses.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Adenosine; Adult; Aged; Blood Pressure; Coronary Stenosis; Coronary Vessels; Enzyme Inhibitors; Female; Fractional Flow Reserve, Myocardial; Heart Rate; Humans; Hyperemia; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Positron-Emission Tomography; Research Design; Severity of Illness Index; Vasodilation; Vasodilator Agents

2007
Contracting human skeletal muscle maintains the ability to blunt α1 -adrenergic vasoconstriction during KIR channel and Na(+) /K(+) -ATPase inhibition.
    The Journal of physiology, 2015, Jun-15, Volume: 593, Issue:12

    Topics: Adenosine; Adult; Barium Compounds; Brachial Artery; Chlorides; Exercise; Female; Forearm; Hand Strength; Humans; Ketorolac; Male; Muscle Contraction; Muscle, Skeletal; omega-N-Methylarginine; Ouabain; Potassium Channels, Inwardly Rectifying; Propranolol; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Young Adult

2015

Other Studies

59 other study(ies) available for omega-n-methylarginine and adenosine

ArticleYear
Role of endothelium-derived relaxing factor in the in vivo renal vascular action of adenosine in dogs.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Arginine; Dogs; Female; Hemodynamics; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenethylamines; Renal Circulation; Theophylline

1992
Adenosine release in morphine-induced hypotension in rats.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Blood Pressure; Dipyridamole; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Male; Morphine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Tetrabenazine; Theophylline

1992
Role of endothelium-derived nitric oxide in myocardial reactive hyperemia.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 2

    Topics: Adenosine; Animals; Arginine; Cardiomyopathies; Coronary Circulation; Dogs; Drug Combinations; Endothelium, Vascular; Hyperemia; Nitric Oxide; omega-N-Methylarginine; Pharmaceutical Vehicles; Theophylline

1992
Endothelium-derived nitric oxide as a mediator of acetylcholine-induced coronary vasodilation in dogs.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:5

    Topics: Acetylcholine; Adenosine; Animals; Arginine; Coronary Circulation; Dogs; Endothelium, Vascular; Female; Male; Muscle Tonus; Nitric Oxide; omega-N-Methylarginine; Vasodilation

1991
Effects of L-NMMA and L-NNA on the selective ATP-induced enhancement of intratumoral blood flow.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Brain Neoplasms; Glioma; Male; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow; Tumor Cells, Cultured

1992
Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Arginine; Hyperemia; Leukocytes; Male; Microcirculation; Motor Neurons; Muscle Tonus; Muscle, Smooth, Vascular; Muscles; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Perfusion; Platelet Aggregation; Rabbits; Vasodilation

1990
Epicardial and endocardial coronary microvascular responses: effects of ischemia-reperfusion.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:4

    Topics: Adenosine; Animals; Arginine; Bradykinin; Calcimycin; Coronary Circulation; Endocardium; Endothelium, Vascular; Female; Glyburide; Guanylate Cyclase; Indomethacin; Male; Microcirculation; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Reperfusion Injury; Serotonin; Swine

1994
Contribution of nitric oxide to coronary vasodilation during hypercapnic acidosis.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Acetylcholine; Acidosis; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Dogs; Endothelium, Vascular; Extracorporeal Circulation; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxygen; Partial Pressure; Vasodilation

1995
Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans.
    Circulation, 1995, Oct-15, Volume: 92, Issue:8

    Topics: Adenosine; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Potassium Channels; Quinidine; Regional Blood Flow; Tolbutamide; Vasodilation; Vasodilator Agents; Verapamil

1995
Direct in vivo observation of subendocardial arteriolar response during reactive hyperemia.
    Circulation research, 1995, Volume: 77, Issue:3

    Topics: Adenosine; Animals; Arginine; Arterioles; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Theophylline; Vasodilation

1995
Adenosine enhances nitric oxide production by vascular endothelial cells.
    The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 1

    Topics: Adenosine; Animals; Arginine; Carotid Arteries; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Nitric Oxide; omega-N-Methylarginine; Saphenous Vein; Swine; Theophylline

1995
Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:4

    Topics: Acetylcholine; Adenosine; Adult; Arginine; Arteriosclerosis; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Female; Humans; Male; Microcirculation; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rest; Risk Factors; Vascular Resistance; Vasodilation

1995
Role of endothelium in hyperpolarization of coronary smooth muscle by adenosine and its analogues.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Swine; Theophylline; Vasodilator Agents

1995
Enhancement of endothelium-dependent contraction of the canine coronary artery by UW solution.
    Transplantation, 1994, Dec-27, Volume: 58, Issue:12

    Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Arginine; Cell Communication; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Glutathione; Hypoxia; Insulin; Isoproterenol; Male; Nitric Oxide; omega-N-Methylarginine; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose; Time Factors; Vasoconstriction; Vasodilation

1994
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline

1994
Prior episode of anoxia attenuates vasorelaxation in response to subsequent episode of anoxia.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 2

    Topics: Adenosine; Animals; Aorta; Arginine; Calcium; Endothelium, Vascular; Free Radicals; Hypoxia; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Purinergic P1 Receptor Antagonists; Rats; Recurrence; Vasodilation

1994
Effects of regional inhibition of nitric oxide synthesis in intact porcine hearts.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 2

    Topics: Adenosine; Adenosine Diphosphate; Animals; Arginine; Coronary Circulation; Female; Hemodynamics; Hyperemia; Male; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxygen Consumption; Swine; Time Factors

1994
Mechanisms of CBF augmentation during hypoxia in cats: probable participation of prostacyclin, nitric oxide and adenosine.
    The Keio journal of medicine, 1994, Volume: 43, Issue:1

    Topics: Adenosine; Animals; Arginine; Caffeine; Cats; Cerebrovascular Circulation; Epoprostenol; Hypoxia; Indomethacin; Nitric Oxide; omega-N-Methylarginine

1994
Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta.
    European journal of pharmacology, 1994, Mar-11, Volume: 254, Issue:1-2

    Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Muscle Denervation; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline

1994
L-arginine analogues blunt prostaglandin-related dilation of arterioles.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: Acetylcholine; Adenosine; Animals; Arachidonic Acids; Arginine; Arterioles; Blood Pressure; Dinoprostone; Dose-Response Relationship, Drug; Male; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Wistar; Vasodilation

1993
Flow-mediated vasodilation of human epicardial coronary arteries: effect of inhibition of nitric oxide synthesis.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:2

    Topics: Acetylcholine; Adenosine; Arginine; Blood Flow Velocity; Cardiac Catheterization; Coronary Angiography; Coronary Circulation; Coronary Vessels; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation; Vasodilator Agents

1996
Pulse pressure-related changes in coronary flow in vivo are modulated by nitric oxide and adenosine.
    Circulation research, 1996, Volume: 79, Issue:4

    Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Dogs; Enzyme Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

1996
Role of nitric oxide in histamine-induced increases in permeability of the blood-brain barrier.
    Brain research, 1996, Dec-16, Volume: 743, Issue:1-2

    Topics: Adenosine; Animals; Arterioles; Blood-Brain Barrier; Drug Evaluation, Preclinical; Histamine; Histamine Antagonists; Molecular Weight; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred WF; Vasodilator Agents

1996
Altered endothelial and smooth muscle cell reactivity caused by University of Wisconsin preservation solution in human saphenous vein.
    Journal of vascular surgery, 1997, Volume: 25, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine; Allopurinol; Cardioplegic Solutions; Cold Temperature; Coronary Artery Bypass; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Hot Temperature; Humans; Insulin; Isotonic Solutions; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Organ Preservation Solutions; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Raffinose; Saphenous Vein; Serotonin; Thromboxane A2; Tissue Preservation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1997
Adenosine stimulates nitric oxide synthesis in rat cardiac myocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Dactinomycin; Enzyme Inhibitors; Heart; Humans; Interleukin-1; Isoproterenol; Myocardium; Naphthalenes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Stereoisomerism; Theophylline; Xanthines

1997
Adenosine receptor-mediated relaxation of rabbit airway smooth muscle: a role for nitric oxide.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Bronchi; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenethylamines; Potassium Chloride; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1

1997
Nitric oxide-mediated flow-dependent dilation is impaired in coronary arteries in patients with coronary spastic angina.
    Journal of the American College of Cardiology, 1997, Volume: 30, Issue:4

    Topics: Adenosine; Adult; Aged; Angina Pectoris, Variant; Case-Control Studies; Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Echocardiography, Doppler; Electrocardiography; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation; Vasodilator Agents

1997
Microsphere-induced bronchial artery vasodilation: role of adenosine, prostacyclin, and nitric oxide.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Animals; Bronchial Arteries; Dipyridamole; Enzyme Inhibitors; Epoprostenol; Lactic Acid; Microspheres; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Sheep; Vasodilation; Xanthines

1998
Role of nitric oxide in adenosine-induced vasodilation in humans.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:5

    Topics: Adenosine; Adolescent; Adult; Enzyme Inhibitors; Forearm; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation; Vasodilator Agents

1998
Endothelium-dependent changes in retinal blood flow following ischemia.
    Current eye research, 1998, Volume: 17, Issue:8

    Topics: Acetylcholine; Adenosine; Animals; Animals, Newborn; Blood Flow Velocity; Endothelin Receptor Antagonists; Endothelium, Vascular; Enzyme Inhibitors; Fluorescein Angiography; Hyperoxia; Hypoxia; Ischemia; Isoxazoles; Nitric Oxide Synthase; omega-N-Methylarginine; Reperfusion; Retinal Vessels; Swine; Thioinosine; Thiophenes

1998
Cardiovascular effects of nitric oxide and adenosine in the nucleus tractus solitarii of rats.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:6

    Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiovascular Agents; Enzyme Inhibitors; Heart Rate; Male; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Sodium Chloride; Solitary Nucleus; Xanthines

1998
Acetylcholine-induced and nitric oxide-mediated vasodilation in burns.
    The Journal of surgical research, 1998, Volume: 80, Issue:2

    Topics: Acetylcholine; Adenosine; Animals; Arterioles; Burns; Endothelium, Vascular; Enzyme Inhibitors; Male; Microcirculation; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasodilation

1998
Additive effects of late preconditioning produced by monophosphoryl lipid A and the early preconditioning mediated by adenosine receptors and KATP channel.
    Circulation, 1999, Jun-29, Volume: 99, Issue:25

    Topics: Adenosine; Animals; Cells, Cultured; Chick Embryo; Ischemic Preconditioning, Myocardial; Lipid A; Myocardium; omega-N-Methylarginine; Pinacidil; Potassium Channels; Purinergic P1 Receptor Agonists; Vasodilator Agents

1999
Prolonged diastolic time fraction protects myocardial perfusion when coronary blood flow is reduced.
    Circulation, 1999, Jul-06, Volume: 100, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Cardiac Pacing, Artificial; Cardiovascular Agents; Coronary Circulation; Diastole; Dogs; Enzyme Inhibitors; Heart; Muscle Relaxation; Myocardial Ischemia; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Time Factors; Vascular Resistance

1999
The role of nitric oxide in bradykinin-induced dilation of coronary resistance vessels in patients with hypercholesterolemia.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:5

    Topics: Acetylcholine; Adenosine; Blood Flow Velocity; Bradykinin; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypercholesterolemia; Infusions, Intra-Arterial; Laser-Doppler Flowmetry; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation

1999
Regulation of shear stress in the canine coronary microcirculation.
    Circulation, 1999, Oct-05, Volume: 100, Issue:14

    Topics: Adenosine; Animals; Coronary Circulation; Dogs; Microcirculation; Nitric Oxide; omega-N-Methylarginine; Stress, Mechanical

1999
Contribution of vasodilator prostanoids and nitric oxide to resting flow, metabolic vasodilation, and flow-mediated dilation in human coronary circulation.
    Circulation, 1999, Nov-09, Volume: 100, Issue:19

    Topics: Adenosine; Adult; Aged; Aspirin; Coronary Circulation; Female; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Vascular Resistance; Vasodilation

1999
Enhanced negative chronotropy by inhibitory receptors in transgenic heart overexpressing beta(2)-adrenoceptors.
    Journal of the autonomic nervous system, 2000, Mar-15, Volume: 79, Issue:2-3

    Topics: Acetylcholine; Adenosine; Aminoquinolines; Animals; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Guanylate Cyclase; Heart Rate; In Vitro Techniques; Mice; Mice, Transgenic; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Pertussis Toxin; Receptors, Adrenergic, beta; Receptors, Purinergic; Virulence Factors, Bordetella

2000
Reversal of glibenclamide-induced coronary vasoconstriction by enhanced perfusion pulsatility: possible role for nitric oxide.
    Cardiovascular research, 2000, Volume: 45, Issue:4

    Topics: Acetylcholine; Adenosine; Animals; Arginine Vasopressin; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium Channel Blockers; Pulsatile Flow; Quinacrine; Vasoconstrictor Agents

2000
Contribution of bradykinin receptor dysfunction to abnormal coronary vasomotion in humans.
    Journal of the American College of Cardiology, 2000, Nov-01, Volume: 36, Issue:5

    Topics: Acetylcholine; Adenosine; Arteriosclerosis; Bradykinin; Coronary Vessels; Female; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptors, Bradykinin; Risk Factors; Vasomotor System

2000
Adenosine signaling in outer medullary descending vasa recta.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Ionophores; Kidney Medulla; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thromboxane A2; Vasodilation

2001
Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:7

    Topics: Adenosine; Animals; Arginase; Arterioles; Coronary Vessels; Eflornithine; Endothelium, Vascular; Enzyme Inhibitors; Immunohistochemistry; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Swine; Vasodilation

2001
Alterations in nitric oxide activity and sensitivity in early streptozotocin-induced diabetes depend on arteriolar size.
    International journal of experimental diabetes research, 2000, Volume: 1, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Arterioles; Blood Glucose; Blood Pressure; Cardiac Output; Diabetes Mellitus, Experimental; Heart Rate; Insulin; Male; Microscopy, Video; Muscle, Skeletal; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Reference Values; Time Factors; Vasodilation

2000
Adenosine linking reduced O2 to arteriolar NO release in intestine is not formed from extracellular ATP.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arterioles; Enzyme Inhibitors; Extracellular Space; Intestine, Small; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Sprague-Dawley; Vascular Patency; Vasoconstriction; Xanthines

2001
Increased inactivation of nitric oxide is involved in impaired coronary flow reserve in heart failure.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:6

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Adenosine; Animals; Coronary Circulation; Dogs; Echocardiography; Endothelium, Vascular; Enzyme Inhibitors; Heart Failure; Hyperemia; Immunohistochemistry; Indicators and Reagents; Lipid Peroxidation; Myocardium; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Pacemaker, Artificial; Reactive Oxygen Species; Tachycardia; Vasodilator Agents

2001
Endothelial dysfunction of coronary resistance vessels in apoE-/- mice involves NO but not prostacyclin-dependent mechanisms.
    Cardiovascular research, 2002, Volume: 53, Issue:1

    Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Apolipoproteins E; Bradykinin; Cholesterol, LDL; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Hypercholesterolemia; Iloprost; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Superoxide Dismutase; Vascular Resistance; Vasodilator Agents

2002
Coronary blood flow regulation in exercising swine involves parallel rather than redundant vasodilator pathways.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Circulation; Enzyme Inhibitors; Female; Glyburide; Hemodynamics; Hypoglycemic Agents; In Vitro Techniques; KATP Channels; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxygen Consumption; Physical Exertion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rest; Swine; Theophylline; Vasodilation

2003
Free radicals potentiate the negative dromotropic effect of adenosine in guinea pig isolated heart.
    Acta cardiologica, 2003, Volume: 58, Issue:3

    Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bundle of His; Female; Free Radicals; Guinea Pigs; Heart; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Purinergic P1 Receptor Antagonists; Pyrogallol; Xanthines

2003
Endothelium-dependent relaxation of canine pulmonary artery after prolonged lung graft preservation in University of Wisconsin solution: role of L-arginine supplementation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004, Volume: 23, Issue:5

    Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Arginine; Dogs; Endothelium, Vascular; Female; Glutathione; Insulin; Lung; Lung Transplantation; Male; Molsidomine; omega-N-Methylarginine; Organ Preservation Solutions; Pulmonary Artery; Raffinose; Sodium Fluoride; Tissue Preservation

2004
Systemic inhibition of nitric oxide synthase unmasks neural constraint of maximal myocardial blood flow in humans.
    Circulation, 2004, Sep-14, Volume: 110, Issue:11

    Topics: Adenosine; Adult; Autonomic Denervation; Blood Pressure; Coronary Circulation; Dose-Response Relationship, Drug; Heart; Heart Rate; Heart Transplantation; Humans; Hyperemia; Male; Middle Aged; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Positron-Emission Tomography; Postoperative Period; Rest; Vasoconstriction

2004
Letter regarding article by Kaufmann et al, "systemic inhibition of nitric oxide synthase unmasks neural constraint of maximal myocardial blood flow in humans".
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: Adenosine; Coronary Circulation; Heart; Heart Transplantation; Humans; Nitric Oxide Synthase Type I; omega-N-Methylarginine

2005
Relation of Basal coronary nitric oxide activity to the burden of atherosclerosis.
    The American journal of cardiology, 2005, May-15, Volume: 95, Issue:10

    Topics: Adenosine; Blood Flow Velocity; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Enzyme Inhibitors; Female; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Pulsatile Flow; Severity of Illness Index; Ultrasonography

2005
Mechanisms of adenosine-induced renal vasodilatation in hypertensive patients.
    Journal of hypertension, 2005, Volume: 23, Issue:9

    Topics: Adenosine; Adult; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hypertension; Hypertension, Renovascular; Male; Middle Aged; omega-N-Methylarginine; Renal Circulation; Time Factors; Vasodilation

2005
Bimodal distribution of vasodilator responsiveness to adenosine due to difference in nitric oxide contribution: implications for exercise hyperemia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:2

    Topics: Acetylcholine; Adenosine; Adult; Brachial Artery; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exercise; Female; Forearm; Humans; Hyperemia; Isoproterenol; Male; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Vasodilation; Vasodilator Agents

2006
Adaptation of coronary microvascular exchange in arterioles and venules to exercise training and a role for sex in determining permeability responses.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: Adaptation, Physiological; Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Albumins; Animals; Arterioles; Atrial Natriuretic Factor; Capillary Permeability; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Physical Endurance; Research Design; Sex Factors; Signal Transduction; Swine; Swine, Miniature; Venules

2007
ATP-induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Adult; Blood Flow Velocity; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indomethacin; Infusions, Intra-Arterial; Lower Extremity; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Regional Blood Flow; RNA, Messenger; Signal Transduction; Theophylline; Vasodilation; Young Adult

2009
Adenosine contributes to blood flow regulation in the exercising human leg by increasing prostaglandin and nitric oxide formation.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:6

    Topics: Adenosine; Adult; Analysis of Variance; Cohort Studies; Exercise; Humans; Hyperemia; Indomethacin; Leg; Male; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Reference Values; Regional Blood Flow; Sensitivity and Specificity; Theophylline; Vasodilation; Young Adult

2009
A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:7

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatic Artery; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Vascular Resistance; Vasodilation; Vasodilator Agents

2010
Ischemic exercise hyperemia in the human forearm: reproducibility and roles of adenosine and nitric oxide.
    European journal of applied physiology, 2012, Volume: 112, Issue:6

    Topics: Adenosine; Adult; Aminophylline; Blood Pressure; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Ischemia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Purinergic P1; Regional Blood Flow; Vasodilation

2012