Page last updated: 2024-09-03

omega-n-methylarginine and 1-methyl-3-isobutylxanthine

omega-n-methylarginine has been researched along with 1-methyl-3-isobutylxanthine in 29 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010)
(omega-n-methylarginine)
Studies
(1-methyl-3-isobutylxanthine)
Trials
(1-methyl-3-isobutylxanthine)
Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
4,4113443365,1485279

Protein Interaction Comparison

ProteinTaxonomyomega-n-methylarginine (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's23 (79.31)18.2507
2000's6 (20.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Catravas, JD; Marczin, N; Ryan, US1
Gillespie, JS; Sheng, H1
Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO1
Anggard, E; Mollace, V; Salvemini, D; Vane, J1
Giles, WR; Han, X; Shimoni, Y1
Fujitani, Y; Karaki, H; Okada, T; Ueda, H; Urade, Y1
Craven, PA; DeRubertis, FR; Studer, RK1
Ando, J; Kamiya, A; Korenaga, R; Sakuma, I; Toyo-oka, T; Tsuboi, H; Yang, W1
Hirata, Y; Imai, T; Kanno, K; Marumo, F1
Marumo, F; Nonoguchi, H; Owada, A; Sakamoto, H; Terada, Y; Tomita, K1
De Kimpe, SJ; Nijkamp, FP; Radomski, MW; van Amsterdam, JG; Van Heuven-Nolsen, D1
Catravas, JD; Cheng, C; Marczin, N; Milici, A; Papapetropoulos, A; Snead, MD1
Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M1
Chik, CL; Ho, AK; Murdoch, G; Ogiwara, T1
Ikeda, M; Ikeda, U; Kano, S; Ohkawa, F; Shimada, K1
Bousquet, J; Dugas, B; Paul-Eugène, N; Pène, J1
Bartoli, F; Billiar, TR; Di Silvio, M; Dorko, K; Freeswick, P; Geller, DA; Liu, ZZ; Nussler, AK1
Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML1
Damais, C; Frelin, C; Vigne, P1
Blum, G; Caramelo, C; Casado, S; Gallego, MJ; López Farré, A; Montón, M; Riesco, A1
Barber, DA; Crotty, TB; Gloviczki, P; Katusic, ZS; Kullo, IJ; Mozes, G; O'Brien, T; Schwartz, RS1
Birder, LA; Finkel, MS; Kanai, AJ; Malinski, T; Mesaros, S; Oddis, CV1
LaPointe, MC; Marsh, JD; Ritchie, RH; Schiebinger, RJ1
Ikeda, M; Kawase, T; Matsumoto, S; Nishikawa, T; Takahashi, T; Yoshida, S1
Belén Herrero, M; Chatterjee, S; de Lamirande, E; Gagnon, C; Lefièvre, L1
Chen, MC; Eizirik, DL; Gysemans, C; Mathieu, C; Proost, P1
Andric, SA; Kostic, TS; Stojilkovic, SS1
Lutz, T; Riediger, T; Schmid, HA; Simon, E1
Colledge, WH; Grace, AA; Joseph, SS; Kaumann, AJ; Lynham, JA; Molenaar, P1

Other Studies

29 other study(ies) available for omega-n-methylarginine and 1-methyl-3-isobutylxanthine

ArticleYear
Endothelial cGMP does not regulate basal release of endothelium-derived relaxing factor in culture.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Vasodilator Agents

1992
The effects of pyrogallol and hydroquinone on the response to NANC nerve stimulation in the rat anococcygeus and the bovine retractor penis muscles.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Autonomic Nervous System; Cattle; Electric Stimulation; Hydroquinones; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Penis; Pyrogallol; Rats; Superoxides

1990
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
    Biochemical and biophysical research communications, 1991, Nov-27, Volume: 181, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats

1991
Nitric oxide from vascular smooth muscle cells: regulation of platelet reactivity and smooth muscle cell guanylate cyclase.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Atrial Natriuretic Factor; Blood Platelets; Cattle; Cyclic GMP; Cycloheximide; Escherichia coli; Guanylate Cyclase; Humans; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Monocytes; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Superoxide Dismutase; Thrombin

1991
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
    The Journal of general physiology, 1995, Volume: 106, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides

1995
A selective agonist of endothelin type B receptor, IRL 1620, stimulates cyclic GMP increase via nitric oxide formation in rat aorta.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arginine; Binding Sites; Calcium; Cyclic GMP; Cytosol; Drug Interactions; Endothelins; Endothelium, Vascular; Kinetics; Male; Membranes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Endothelin; Stimulation, Chemical; Time Factors

1993
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2

1994
Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells.
    Biochemical and biophysical research communications, 1994, Jan-14, Volume: 198, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Arginine; Calcium; Cattle; Cells, Cultured; Cyclic GMP; Egtazic Acid; Endothelium, Vascular; Fetus; Kinetics; Nitric Oxide; omega-N-Methylarginine; Stress, Mechanical

1994
Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; RNA, Ribosomal

1994
Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Calmodulin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Glomerular Mesangium; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Methylene Blue; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides

1994
Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cattle; Cyclic GMP; In Vitro Techniques; Interferon-gamma; Mesenteric Arteries; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Vasodilation

1994
Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Base Sequence; Blotting, Northern; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Oligonucleotide Probes; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Vasodilation

1994
Insulin increases guanosine-3',5'-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect.
    Diabetes, 1994, Volume: 43, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Amino Acid Oxidoreductases; Arginine; Blood Platelets; Collagen; Cyclic GMP; Female; Genistein; Guanylate Cyclase; Humans; Insulin; Isoflavones; Male; Methylene Blue; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Radioimmunoassay; Recombinant Proteins

1994
Tyrosine kinase inhibitors enhance cGMP production in rat pinealocytes.
    Biochemical and biophysical research communications, 1995, Feb-27, Volume: 207, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Catechols; Cyclic AMP; Cyclic GMP; Genistein; Hydroquinones; Isoflavones; Isoproterenol; Male; Nitric Oxide Synthase; Nitriles; Norepinephrine; omega-N-Methylarginine; Pineal Gland; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrphostins

1995
Nitric oxide synthesis in rat mesangial cells induced by cytokines.
    Cytokine, 1994, Volume: 6, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Chemotactic Factors; Cyclic GMP; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression; Glomerular Mesangium; Interleukin-1; Interleukin-6; Interleukin-8; Kinetics; Male; Monocyte Chemoattractant Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Transforming Growth Factor beta

1994
Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4.
    Cytokine, 1995, Volume: 7, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; B-Lymphocytes; Cholera Toxin; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Gene Expression Regulation; Humans; Immunoglobulin E; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Recombinant Fusion Proteins

1995
Further characterization and comparison of inducible nitric oxide synthase in mouse, rat, and human hepatocytes.
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Dexamethasone; Enzyme Induction; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Interleukins; Isoenzymes; Lipopolysaccharides; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Species Specificity; Tumor Necrosis Factor-alpha

1995
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
    Diabetologia, 1993, Volume: 36, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides

1993
IL1 and TNF alpha induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway.
    Brain research, 1993, Mar-26, Volume: 606, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Arginine; Astrocytoma; Cyclic GMP; Interleukin-1; Nitrites; omega-N-Methylarginine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
    The Biochemical journal, 1993, Jun-15, Volume: 292 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine

1993
Adventitial gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries alters vascular reactivity.
    Circulation, 1997, Oct-07, Volume: 96, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; beta-Galactosidase; Calcimycin; Calcium; Carotid Arteries; Cattle; Cloning, Molecular; Cyclic GMP; Cytomegalovirus; Endothelium, Vascular; Gene Transfer Techniques; Genetic Vectors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phenylephrine; Rabbits; Recombinant Fusion Proteins

1997
Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Animals, Newborn; Bucladesine; Calcimycin; Cells, Cultured; Dobutamine; Enzyme Induction; Guanosine Diphosphate; Heart; Interleukin-1; Isoproterenol; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Receptors, Adrenergic, beta; Terbutaline; Thionucleotides; Trifluoperazine

1997
Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Bradykinin; Cardiomegaly; Cells, Cultured; Coculture Techniques; Cyclic GMP; Endothelium, Vascular; Heart; Iloprost; Indomethacin; Male; Molsidomine; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Phenylalanine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley

1998
Effects of N(G)-monomethyl-L-arginine on Ca(2+) current and nitric-oxide synthase in rat ventricular myocytes.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Milrinone; NADPH Dehydrogenase; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats

2000
Nitric oxide interacts with the cAMP pathway to modulate capacitation of human spermatozoa.
    Free radical biology & medicine, 2000, Sep-15, Volume: 29, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electron Spin Resonance Spectroscopy; Humans; Hydrazines; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Phosphorylation; Signal Transduction; Sperm Capacitation; Spermatozoa; Spermine; Sulfonamides; Tyrosine

2000
Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells.
    Diabetologia, 2001, Volume: 44, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Chemokine CCL2; Diabetes Mellitus, Type 1; Female; Flow Cytometry; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-1; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; omega-N-Methylarginine; p38 Mitogen-Activated Protein Kinases; Prediabetic State; Rats; Rats, Wistar; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

2001
Spontaneous and receptor-controlled soluble guanylyl cyclase activity in anterior pituitary cells.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gonadotropin-Releasing Hormone; Growth Hormone-Releasing Hormone; Guanidines; Guanylate Cyclase; Immunoblotting; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Thyrotropin-Releasing Hormone

2001
Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Amyloid; Animals; Cerebral Ventricles; Cyclic GMP; Genes, fos; In Vitro Techniques; Islet Amyloid Polypeptide; Male; Neurons; omega-N-Methylarginine; Peptide Fragments; Peptides; Rats; Rats, Wistar; Second Messenger Systems

2001
Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Animals; Binding Sites; CHO Cells; Cricetinae; Cyclic AMP; Drug Interactions; Drug Resistance; Female; Heart; Heart Atria; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Norepinephrine; omega-N-Methylarginine; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Recombinant Proteins; Stereoisomerism; Sympathomimetics

2003