Compounds > omega-n-methylarginine
Page last updated: 2024-09-03

omega-n-methylarginine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

omega-n-methylarginine has been researched along with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine in 8 studies

Compound Research Comparison

Studies
(omega-n-methylarginine)		Trials
(omega-n-methylarginine)		Recent Studies (post-2010)
(omega-n-methylarginine)		Studies
(1-(5-isoquinolinesulfonyl)-2-methylpiperazine)		Trials
(1-(5-isoquinolinesulfonyl)-2-methylpiperazine)		Recent Studies (post-2010) (1-(5-isoquinolinesulfonyl)-2-methylpiperazine)
4,4113443363,41241631

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Day, RW; Ignarro, LJ; Klitzner, TS; Lai, WW1
Craven, PA; DeRubertis, FR; Studer, RK1
Fischer, T; Mohaupt, MG; Schulze-Lohoff, E; Schwöbel, J; Sterzel, RB1
Chayama, K; Goto, C; Hara, K; Higashi, Y; Jitsuiki, D; Kimura, M; Nakagawa, K; Noma, K; Oshima, T; Yoshizumi, M1
Chayama, K; Goto, C; Hara, K; Higashi, Y; Jitsuiki, D; Kimura, M; Nakagawa, K; Nishioka, K; Noma, K; Oshima, T; Umemura, T; Yoshizumi, M1
Büssemaker, E; Herbrig, K; Palm, C; Passauer, J; Pistrosch, F1
Andersson, DC; Fedotovskaya, O; Gonon, AT; Kiss, A; Lanner, JT; Pernow, J; Tratsiakovich, Y; Yang, J1
Gonon, AT; Kiss, A; Pernow, J; Sjöquist, PO; Tratsiakovich, Y; Yang, J1

Trials

1 trial(s) available for omega-n-methylarginine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

ArticleYear
Smoking activates rho-kinase in smooth muscle cells of forearm vasculature in humans.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Adult; Blood Pressure; Enzyme Inhibitors; Forearm; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Protein Serine-Threonine Kinases; Regional Blood Flow; rho-Associated Kinases; Smoking; Vasodilator Agents

2003

Other Studies

7 other study(ies) available for omega-n-methylarginine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

ArticleYear
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
    Developmental pharmacology and therapeutics, 1992, Volume: 19, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits

1992
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2

1994
Activation of purinergic P2Y2 receptors inhibits inducible NO synthase in cultured rat mesangial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Glomerular Mesangium; Indoles; Interferon-gamma; Lipopolysaccharides; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1998
Smoking, endothelial function, and Rho-kinase in humans.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Adult; Antioxidants; Ascorbic Acid; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Plethysmography; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Regional Blood Flow; rho-Associated Kinases; Smoking; Vasodilator Agents

2005
Role of rho-kinase in the regulation of vascular tone in hypertensive renal transplant recipients.
    Atherosclerosis, 2009, Volume: 207, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Case-Control Studies; Dose-Response Relationship, Drug; Enzyme Activation; Forearm; Humans; Hypertension; Infusions, Intra-Arterial; Kidney Transplantation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Plethysmography; Protein Kinase Inhibitors; Regional Blood Flow; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2009
The role of arginase and rho kinase in cardioprotection from remote ischemic perconditioning in non-diabetic and diabetic rat in vivo.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Ischemic Preconditioning; Male; Myocardial Reperfusion Injury; omega-N-Methylarginine; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction

2014
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.
    Diabetes & vascular disease research, 2017, Volume: 14, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Arginine; Cytoprotection; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction

2017