Page last updated: 2024-08-23

oltipraz and sulforaphane

oltipraz has been researched along with sulforaphane in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Baird, L; Bertrand, HC; Dinkova-Kostova, AT; Fowkes, A; Georgakopoulos, ND; Kachi, H; Schaap, M; Thiollier, C; Wells, G1
Fei, P; Kong, AN; Matwyshyn, GA; Rushmore, TH1
Guillouzo, A; Langouët, S; Mahéo, K; Morel, F1
Furge, LL; Guengerich, FP; Guillouzo, A; Kerriguy, N; Langouët, S; Nakamura, K1
Chun, JA; Furge, LL; Haab, BB; Haddad, R; Klenow, S; Konwinski, RR; Larson, SC1
Delude, RL; Englert, JA; Fink, MP; Han, Y; Kellum, JA; Killeen, ME; Song, M; Stolz, DB1
Kensler, TW; Yates, MS1
Ali, M; Bonay, M; Deramaudt, TB; Vanhee, V; Vinit, S1

Reviews

2 review(s) available for oltipraz and sulforaphane

ArticleYear
The use of primary hepatocyte cultures for the evaluation of chemoprotective agents.
    Cell biology and toxicology, 1997, Volume: 13, Issue:4-5

    Topics: Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Cells, Cultured; Humans; Isothiocyanates; Liver; Pyrazines; Rats; Sulfoxides; Thiocyanates; Thiones; Thiophenes; Toxicity Tests

1997
Keap1 eye on the target: chemoprevention of liver cancer.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:9

    Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Hepatocellular; Clinical Trials as Topic; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Liver Neoplasms; NF-E2-Related Factor 2; Phenols; Pyrazines; Signal Transduction; Sulfoxides; Thiocyanates; Thiones; Thiophenes; Triterpenes

2007

Other Studies

6 other study(ies) available for oltipraz and sulforaphane

ArticleYear
Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction.
    Journal of medicinal chemistry, 2015, Sep-24, Volume: 58, Issue:18

    Topics: Cell Line, Tumor; Click Chemistry; Computer Simulation; Databases, Chemical; Dose-Response Relationship, Drug; Fluorescence Polarization; HEK293 Cells; Heme Oxygenase-1; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Molecular Docking Simulation; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Protein Binding; Structure-Activity Relationship; Sulfoxides; Triazoles

2015
Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents.
    Pharmaceutical research, 1996, Volume: 13, Issue:7

    Topics: Anticarcinogenic Agents; Blotting, Northern; Chloramphenicol O-Acetyltransferase; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation; Genes, Reporter; Glutathione Transferase; Humans; Isothiocyanates; Liver; Pyrazines; Sulfoxides; Tamoxifen; Thiocyanates; Thiones; Thiophenes; Time Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured

1996
Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane.
    Chemical research in toxicology, 2000, Volume: 13, Issue:4

    Topics: Anticarcinogenic Agents; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Humans; Isothiocyanates; Pyrazines; Quinolines; Sulfoxides; Thiocyanates; Thiones; Thiophenes

2000
Oltipraz, 3H-1,2-dithiole-3-thione, and sulforaphane induce overlapping and protective antioxidant responses in murine microglial cells.
    Toxicology letters, 2004, Nov-28, Volume: 153, Issue:3

    Topics: Animals; Antioxidants; Blotting, Western; Cell Line; Cells, Cultured; DNA, Complementary; Hydrogen Peroxide; Isothiocyanates; Lipopolysaccharides; Mice; Microglia; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Oxidants; Oxidative Stress; Pyrazines; Reactive Oxygen Species; RNA; Stimulation, Chemical; Sulfoxides; Thiocyanates; Thiones; Thiophenes

2004
The phase 2 enzyme inducers ethacrynic acid, DL-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:3

    Topics: Active Transport, Cell Nucleus; Animals; Cells, Cultured; DNA; Enzyme Induction; Ethacrynic Acid; Extracellular Signal-Regulated MAP Kinases; HMGB1 Protein; Interleukin-10; Interleukin-6; Isothiocyanates; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Phosphorylation; Pyrazines; Sulfoxides; Thiocyanates; Thiones; Thiophenes; Tumor Necrosis Factor-alpha

2006
Comparative effectiveness of 4 natural and chemical activators of Nrf2 on inflammation, oxidative stress, macrophage polarization, and bactericidal activity in an in vitro macrophage infection model.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Anti-Inflammatory Agents; Antioxidants; Dimethyl Fumarate; Escherichia coli; Escherichia coli Infections; Flavanones; Humans; Inflammation; Isothiocyanates; Leukocytes, Mononuclear; Macrophage Activation; Macrophages; NF-E2-Related Factor 2; Oxidative Stress; Pyrazines; Staphylococcal Infections; Staphylococcus aureus; Sulfoxides; Thiones; Thiophenes; THP-1 Cells

2020