oltipraz has been researched along with benzo(a)pyrene in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bueding, E; Wattenberg, LW | 1 |
| Kessler, FK; Ritter, JK | 1 |
| Dolan, PM; Itoh, K; Kensler, TW; Kwak, MK; Ramos-Gomez, M; Talalay, P; Yamamoto, M | 1 |
| Auyeung, DJ; Kessler, FK; Ritter, JK | 1 |
| Dolan, PM; Itoh, K; Kensler, TW; Ramos-Gomez, M; Yamamoto, M | 1 |
| Ebert, B; Lampen, A; Seidel, A | 2 |
| Gao, P; Sharma, S; Steele, VE | 1 |
8 other study(ies) available for oltipraz and benzo(a)pyrene
| Article | Year |
|---|---|
Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard.
Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Pyrazines; Stomach Neoplasms; Thiones; Thiophenes; Uracil Mustard | 1986 |
Induction of a rat liver benzo[a]pyrene-trans-7,8-dihydrodiol glucuronidating activity by oltipraz and beta-naphthoflavone.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Enzyme Induction; Female; Glucuronates; Glucuronosyltransferase; Microsomes, Liver; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1997 |
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cell Nucleus; Disease Models, Animal; Disease Susceptibility; DNA-Binding Proteins; Epoxide Hydrolases; Female; FMN Reductase; Gene Expression; Genotype; Glucuronosyltransferase; Glutathione Transferase; Mice; Mice, Inbred ICR; Mice, Knockout; NADH, NADPH Oxidoreductases; NF-E2-Related Factor 2; Pyrazines; Stomach Neoplasms; Thiones; Thiophenes; Trans-Activators | 2001 |
An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.
Topics: 5' Untranslated Regions; Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Digestive System; DNA, Complementary; Exons; Gene Expression; Glucuronosyltransferase; Humans; Kidney; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Promoter Regions, Genetic; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Thiones; Thiophenes | 2001 |
Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; DNA Adducts; DNA-Binding Proteins; Genotype; Mice; Mice, Knockout; NF-E2-Related Factor 2; Pyrazines; Thiones; Thiophenes; Trans-Activators | 2003 |
Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells.
Topics: Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biological Transport; Caco-2 Cells; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Enzyme Induction; Flavones; Gene Expression; Humans; Indoles; Pyrazines; RNA, Messenger; Sulfates; Thiones; Thiophenes | 2005 |
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists.
Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Biological Transport; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Pyrazines; Receptors, Aryl Hydrocarbon; Reserpine; RNA, Messenger; Thiones; Thiophenes | 2005 |
The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Female; Inhalation; Lung Neoplasms; Mice; Mice, Inbred A; Pyrazines; Thiones; Thiophenes | 2006 |