Compounds > oltipraz
Page last updated: 2024-08-23

oltipraz and acetaminophen

oltipraz has been researched along with acetaminophen in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, MH; Schamber, GJ; Schnell, RC1
Davies, MH; Schnell, RC1
Auyeung, DJ; Kessler, FK; Kessler, MR; Ritter, JK1
Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL1
Chang, Y; Hao, B; Li, C; Li, R; Li, Y; Liu, F; Ma, X; Muhammad, I; Shi, C; Wang, F; Yang, Y; Zhang, Y1

Other Studies

5 other study(ies) available for oltipraz and acetaminophen

ArticleYear
Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. I. Lack of dependence on glutathione.
    Toxicology and applied pharmacology, 1991, Jun-01, Volume: 109, Issue:1

    Topics: Acetaminophen; Animals; Cricetinae; Glutathione; Glutathione Disulfide; Liver; Male; Mesocricetus; Oxidation-Reduction; Pyrazines; Schistosomicides; Thiones; Thiophenes

1991
Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. II. Competitive shunt in metabolism via glucuronidation.
    Toxicology and applied pharmacology, 1991, Jun-01, Volume: 109, Issue:1

    Topics: Acetaminophen; Animals; Cricetinae; Glutathione; Liver; Male; Mesocricetus; Models, Biological; Pyrazines; Schistosomicides; Thiones; Thiophenes; Uridine Diphosphate Glucuronic Acid

1991
Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:3

    Topics: Acetaminophen; Analgesics; Animals; Blotting, Western; Catalysis; Cells, Cultured; Chromatography, High Pressure Liquid; Enzyme Induction; Glucuronosyltransferase; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Molecular Sequence Data; Pyrazines; Rats; Rats, Gunn; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiones; Thiophenes

2002
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:9

    Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors

2003
Acetaminophen-induced hepatocyte injury: C2-ceramide and oltipraz intervention, hepatocyte nuclear factor 1 and glutathione S-transferase A1 changes.
    Journal of applied toxicology : JAT, 2019, Volume: 39, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antioxidants; Cell Culture Techniques; Cell Proliferation; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gene Expression; Glutathione Transferase; Hep G2 Cells; Hepatocyte Nuclear Factor 1; Hepatocytes; Humans; Pyrazines; Sphingosine; Thiones; Thiophenes

2019