olsalazine has been researched along with sulfasalazine in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (40.70) | 18.7374 |
| 1990's | 28 (32.56) | 18.2507 |
| 2000's | 13 (15.12) | 29.6817 |
| 2010's | 9 (10.47) | 24.3611 |
| 2020's | 1 (1.16) | 2.80 |
| Authors | Studies |
|---|---|
| Gubernator, K; Kansy, M; Senner, F | 1 |
| Ghuloum, AM; Jain, AN; Sage, CR | 1 |
| Ertl, P; Rohde, B; Selzer, P | 1 |
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chakrabarti, KS; Choi, J; de Groot, BL; Gapsys, V; Griesinger, C; Ha, JH; Jee, JG; Kim, BR; Kim, M; Lee, D; Lee, KO; Ryu, KS | 1 |
| Drab, EA; Linder, JS; Rubin, DB; Sabesin, SM; Sharon, P; Weidman, SW | 1 |
| Kiilerich, S; Ladefoged, K; Ranløv, PJ; Rannem, T | 1 |
| Giaffer, MH; Holdsworth, CD; O'Brien, CJ | 1 |
| Rijk, MC; van Lier, HJ; van Tongeren, JH | 1 |
| Tolia, V | 1 |
| Maier, KP | 1 |
| Crouch, R; Davis, AE; Patterson, F | 1 |
| Rijk, MC; van Schaik, A; van Tongeren, JH | 3 |
| Zimmerman, J | 1 |
| Barbara, L; Belluzzi, A; Brignola, C; Campieri, M; Gionchetti, P; Guarnieri, C; Iannone, P; Miglioli, M | 2 |
| Frost, PG; Patil, DH; Raimundo, AH; Silk, DB | 1 |
| Grisham, MB; Volkmer, C; Yamada, T | 1 |
| Ditschuneit, H; Horn, H; Preclik, G; Stange, EF | 1 |
| Cann, PA; Corbett, CL; Dundas, SA; Holdsworth, CD; Palmer, KR; Rao, SS | 1 |
| Lauritsen, K | 1 |
| Gratama, S; Mulder, H | 1 |
| Ireland, A; Jewell, DP | 3 |
| Rijk, MC; van Hogezand, RA; van Schaik, A; van Tongeren, JH | 1 |
| van Hees, PA; van Hogezand, RA; van Rossum, JM; van Tongeren, JH; Zwanenburg, B | 1 |
| Levinson, RA | 1 |
| Järnerot, G; Kjellander, J; Sandberg-Gertzen, H; Sundberg-Gillå, B | 1 |
| Gibson, PR; Jewell, DP | 1 |
| Friedman, G | 1 |
| Gustavsson, S; Ryde, M | 1 |
| Järnerot, G; Kraaz, W; Sandberg-Gertzén, H | 1 |
| Bukhave, K; Järnerot, G; Lauritsen, K; Rask-Madsen, J; Sandberg-Gertzén, H | 1 |
| Cann, PA; Holdsworth, CD; Rao, SS | 1 |
| Breiling, J; Franke, M; Gabbert, H; Goerg, KJ; Meyer zum Büschenfelde, KH; Wanitschke, R | 1 |
| Neal, TM; Vissers, MC; Winterbourn, CC | 1 |
| Sullivan, SN | 1 |
| Janowitz, HD; Meyers, S; Present, DH; Sachar, DB | 2 |
| Ireland, A; Jewell, DP; Mason, CH | 1 |
| Nadorp, JH; Scherpenisse, J; van den Bosch, JM; van der Valk, PD; van Hees, PA | 1 |
| Meyers, S | 2 |
| van Hogezand, RA | 1 |
| Truelove, SC | 1 |
| Cowan, RE; Gould, SR; Machell, RJ; Stewart, JB; Willoughby, CP | 1 |
| Eckardt, V; Ewe, K; Kanzler, G | 1 |
| Elmgreen, J; Nielsen, OH; Verspaget, HW | 1 |
| Tangerman, A; van Balen, HC; van Hees, PA; van Hogezand, RA; van Schaik, A; van Tongeren, JH; Zwanenburg, B | 1 |
| Hansen, J; Lauritsen, K; Rask-Madsen, J; Ryde, M | 1 |
| Bukhave, K; Bytzer, P; Hansen, J; Lauritsen, K; Rask-Madsen, J | 1 |
| Garau, P; Kocoshis, SA; Neigut, DA; Orenstein, SR | 1 |
| Augustin, AJ; Lutz, J | 1 |
| Hentschel, E; Judmaier, G; Kayasseh, L; Kratochvil, P; Kruis, W; Scheurlen, C; Stolte, M; Theuer, D | 1 |
| Benno, P; Bergman, L; Danielsson, A; Fausa, O; Florholmen, J; Karvonen, AL; Kildebo, S; Kollberg, B; Löfberg, R; Nilsson, A | 1 |
| Hessemer, CA; Schinagl, EF | 1 |
| Janowitz, HD; Kornbluth, AA; Mitty, R; Sacks, HS; Salomon, P | 1 |
| Ahnfelt-Rønne, I; Berild, D; Bouchelouche, PN; Nielsen, OH | 1 |
| Ferry, GD; Fiedorek, SC; Grand, RJ; Griffiths, AM; Hassall, EG; Issenman, RM; Kirschner, BS; Vanderhoof, JA; Watkins, JB; Winter, HS | 1 |
| Campbell, BJ; Dwarakanath, AD; Morris, AI; Rhodes, JM; Stevenson, A; Stretch, GL; Yaqoob, M | 1 |
| Alam, M; Benno, P; Midtvedt, T; Uribe, A | 1 |
| Steinberg, H | 1 |
| Axelsson, LG; Bylund-Fellenius, AC; Landström, E | 1 |
| Berg, KJ; Birketvedt, GS; Fausa, O; Florholmen, J | 1 |
| Schroeder, KW | 1 |
| Cummings, JH; Edmond, LM; Hopkins, MJ; Magee, EA | 1 |
| Cui, HF; Jiang, XL | 1 |
| Baker, DE; Kane, S | 1 |
| Chang, EB; Hanauer, SB; Kles, KA; Musch, MW; Turner, JR; Vavricka, SR | 1 |
| Sandborn, WJ | 1 |
| Hanauer, SB; Huo, D; LoSavio, A; Rubin, DT; Yadron, N | 1 |
| Boulieu, R; Lachaux, A; Le Gall, C; Nguyen, TM | 1 |
| Dhaneshwar, SS | 1 |
| Hanauer, S; Lim, WC; MacDonald, JK; Wang, Y | 1 |
| Kuriyama, A; Matsumura, M; Urushidani, S | 1 |
11 review(s) available for olsalazine and sulfasalazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug treatment and formation of eicosanoids in patients with chronic inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Diseases; Leukotriene B4; Mesalamine; Prostaglandins; Sulfasalazine; Thromboxane B2 | 1989 |
Sulfasalazine and new analogues.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Enema; Humans; Mesalamine; Sulfasalazine | 1986 |
Evolution of olsalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; History, 20th Century; Humans; Sulfasalazine; Sweden | 1988 |
Meta-analysis of the effectiveness of current drug therapy of ulcerative colitis.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Mesalamine; Placebo Effect; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Steroids; Sulfasalazine; Treatment Outcome | 1993 |
Role of mesalazine in acute and long-term treatment of ulcerative colitis and its complications.
Topics: Acute Disease; Administration, Oral; Administration, Rectal; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Enema; Humans; Mesalamine; Phenylhydrazines; Prodrugs; Sulfasalazine; Time Factors | 2002 |
The short- and long-term safety of 5-aminosalicylate products in the treatment of ulcerative colitis.
Topics: Adolescent; Adult; Aminosalicylic Acids; Child; Clinical Trials as Topic; Colitis, Ulcerative; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Labeling; Female; Humans; Male; Mesalamine; Middle Aged; Phenylhydrazines; Product Surveillance, Postmarketing; Sensitivity and Specificity; Sulfasalazine | 2004 |
Treatment of ulcerative colitis with oral mesalamine: advances in drug formulation, efficacy expectations and dose response, compliance, and chemoprevention.
Topics: Administration, Oral; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chemoprevention; Clinical Trials as Topic; Colitis, Ulcerative; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Mesalamine; Patient Compliance; Phenylhydrazines; Remission Induction; Sulfasalazine | 2006 |
Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Clinical Trials as Topic; Colon; Fatty Acids, Omega-3; Heparin, Low-Molecular-Weight; Humans; Inflammatory Bowel Diseases; Mesalamine; Phenylhydrazines; Prodrugs; Sulfasalazine | 2014 |
Aminosalicylates for induction of remission or response in Crohn's disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Crohn Disease; Delayed-Action Preparations; Gastrointestinal Agents; Humans; Induction Chemotherapy; Mesalamine; Randomized Controlled Trials as Topic; Sulfasalazine | 2016 |
5-aminosalicylic acid agents for prevention of recurrent diverticulitis: A systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Anti-Inflammatory Agents; Databases, Bibliographic; Diverticulitis; Female; Humans; Male; Mesalamine; Middle Aged; Phenylhydrazines; Randomized Controlled Trials as Topic; Recurrence; Secondary Prevention; Sulfasalazine; Treatment Outcome; Young Adult | 2018 |
24 trial(s) available for olsalazine and sulfasalazine
| Article | Year |
|---|---|
Prophylactic effects of olsalazine v sulphasalazine during 12 months maintenance treatment of ulcerative colitis. The Danish Olsalazine Study Group.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Double-Blind Method; Humans; Middle Aged; Recurrence; Sulfasalazine | 1992 |
Relapse-preventing effect and safety of sulfasalazine and olsalazine in patients with ulcerative colitis in remission: a prospective, double-blind, randomized multicenter study. The Ulcerative Colitis Multicenter Study Group.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Recurrence; Sulfasalazine; Survival Analysis | 1992 |
Disposition of mesalazine from mesalazine-delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea.
Topics: Adult; Aged; Aminosalicylic Acids; Delayed-Action Preparations; Diarrhea; Drug Carriers; Feces; Female; Gastrointestinal Transit; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Middle Aged; Sulfasalazine | 1992 |
Olsalazine or sulphasalazine in first attacks of ulcerative colitis? A double blind study.
Topics: Adult; Aged; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Sulfasalazine | 1989 |
Disposition of 5-aminosalicylic acid from 5-aminosalicylic acid-delivering drugs during accelerated intestinal transit in healthy volunteers.
Topics: Adult; Aminosalicylic Acids; Bisacodyl; Female; Gastrointestinal Transit; Humans; Male; Mesalamine; Middle Aged; Sulfasalazine | 1989 |
Sulfasalazine and new analogues.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Enema; Humans; Mesalamine; Sulfasalazine | 1986 |
Azodisal sodium in the treatment of ulcerative colitis. A study of tolerance and relapse-prevention properties.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Chemical Phenomena; Chemistry; Child; Colitis, Ulcerative; Diarrhea; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Male; Middle Aged; Sulfasalazine | 1986 |
Effect of azodisal sodium and sulphasalazine on ileostomy output of fluid and PGE2 and PGF2 alpha in subjects with a permanent ileostomy.
Topics: Adult; Aged; Aminosalicylic Acids; Body Fluids; Clinical Trials as Topic; Dinoprost; Dinoprostone; Double-Blind Method; Feces; Female; Humans; Ileostomy; Male; Middle Aged; Prostaglandins E; Prostaglandins F; Random Allocation; Sulfasalazine | 1986 |
Clinical experience of the tolerance of mesalazine and olsalazine in patients intolerant of sulphasalazine.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Female; Humans; Male; Mesalamine; Middle Aged; Sulfapyridine; Sulfasalazine | 1987 |
Olsalazine sodium in the treatment of ulcerative colitis among patients intolerant of sulfasalazine. A prospective, randomized, placebo-controlled, double-blind, dose-ranging clinical trial.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Placebos; Prospective Studies; Random Allocation; Sulfasalazine | 1987 |
Olsalazine in patients intolerant of sulphasalazine.
Topics: Adult; Aged; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Female; Humans; Male; Middle Aged; Sulfasalazine | 1987 |
Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds.
Topics: Adult; Aminosalicylic Acids; Azo Compounds; Delayed-Action Preparations; Feces; Female; Humans; Male; Mesalamine; Sulfasalazine | 1988 |
Controlled trial comparing olsalazine and sulphasalazine for the maintenance treatment of ulcerative colitis.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Rectum; Recurrence; Sigmoidoscopy; Sulfasalazine | 1988 |
Olsalazine in the treatment of ulcerative colitis among patients intolerant of sulphasalazine: a prospective, randomized, placebo-controlled, double-blind, dose-ranging clinical trial.
Topics: Administration, Oral; Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Prospective Studies; Random Allocation; Sulfasalazine | 1988 |
Evolution of olsalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; History, 20th Century; Humans; Sulfasalazine; Sweden | 1988 |
Double-blind comparison of olsalazine and sulphasalazine in active ulcerative colitis.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Random Allocation; Sulfasalazine | 1988 |
Controlled trial comparing olsalazine and sulphasalazine for maintenance treatment of ulcerative colitis.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Recurrence; Sulfasalazine; Time Factors | 1988 |
Treatment of ulcerative colitis with olsalazine and sulphasalazine: efficacy and side-effects.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Proctitis; Random Allocation; Sulfasalazine | 1988 |
Double-blind dose-finding study of olsalazine versus sulphasalazine as maintenance therapy for ulcerative colitis.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Diarrhea; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Recurrence; Remission Induction; Safety; Sulfasalazine; Treatment Failure; Treatment Outcome | 1995 |
Olsalazine versus sulphasalazine for relapse prevention in ulcerative colitis: a multicenter study.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Diarrhea; Double-Blind Method; Female; Finland; Follow-Up Studies; Humans; Life Tables; Male; Norway; Recurrence; Sulfasalazine; Sweden; Time Factors; Treatment Outcome | 1995 |
Meta-analysis of the effectiveness of current drug therapy of ulcerative colitis.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Mesalamine; Placebo Effect; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Steroids; Sulfasalazine; Treatment Outcome | 1993 |
Olsalazine versus sulfasalazine in mild to moderate childhood ulcerative colitis: results of the Pediatric Gastroenterology Collaborative Research Group Clinical Trial.
Topics: Adolescent; Aminosalicylic Acids; Child; Child, Preschool; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Recurrence; Severity of Illness Index; Sulfasalazine | 1993 |
5-amino salicylic acid absorption and metabolism in ulcerative colitis patients receiving maintenance sulphasalazine, olsalazine or mesalazine.
Topics: Absorption; Acetylation; Acetylglucosaminidase; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Humans; Male; Mesalamine; Middle Aged; Sulfasalazine | 1996 |
Different therapy for different types of ulcerative colitis in China.
Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Antigens, CD; ATP Binding Cassette Transporter, Subfamily B, Member 1; China; Colitis, Ulcerative; Drugs, Chinese Herbal; Epithelial Cells; Female; Houttuynia; Humans; Male; Platelet Activation; Prednisolone; Sulfasalazine; Thrombosis; Thromboxane A2 | 2004 |
54 other study(ies) available for olsalazine and sulfasalazine
| Article | Year |
|---|---|
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet | 1998 |
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship | 1999 |
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results | 2000 |
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IXβ Reductase B as a Novel Thrombocytopenia Therapeutic Target.
Topics: Catalytic Domain; Crystallography, X-Ray; Drug Repositioning; Enzyme Inhibitors; Humans; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Oxidoreductases Acting on CH-CH Group Donors; Protein Binding; Small Molecule Libraries; Thermodynamics; United States; United States Food and Drug Administration | 2022 |
The effect of sulfasalazine on bovine endothelial cell proliferation and cell cycle phase distribution. Comparison with olsalazine, 5-aminosalicylic acid, and sulfapyridine.
Topics: Aminosalicylic Acids; Animals; Cattle; Cell Count; Cell Cycle; Deoxyuridine; Endothelium, Vascular; Mesalamine; Sulfapyridine; Sulfasalazine; Tetrahydrofolates; Thymidine; Time Factors; Tritium | 1992 |
Clinical tolerance to three 5-aminosalicylic acid releasing preparations in patients with inflammatory bowel disease intolerant or allergic to sulphasalazine.
Topics: Aminosalicylic Acids; Drug Hypersensitivity; Female; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Phenylhydrazines; Sulfapyridine; Sulfasalazine | 1992 |
Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease.
Topics: Adolescent; Aminosalicylic Acids; Child; Chronic Disease; Desensitization, Immunologic; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Stevens-Johnson Syndrome; Sulfasalazine | 1992 |
[Aminosalicylates in chronic inflammatory intestinal diseases and rheumatoid arthritis].
Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Humans; Mesalamine; Sulfasalazine | 1992 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Incidence; Inflammatory Bowel Diseases; Male; Mesalamine; Metronidazole; Neoplasm Invasiveness; Rats; Rats, Wistar; Sulfasalazine | 1992 |
Drug interactions in intestinal transport of folic acid and methotrexate. Further evidence for the heterogeneity of folate transport in the human small intestine.
Topics: Aminosalicylic Acids; Biological Transport; Drug Interactions; Folic Acid; Humans; Intestinal Mucosa; Intestine, Small; Methotrexate; Organ Culture Techniques; Sulfasalazine | 1992 |
Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation.
Topics: Aminosalicylic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; In Vitro Techniques; Luminescent Measurements; Mesalamine; Neutrophils; Spectrophotometry; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Effects of olsalazine and sulphasalazine on jejunal and ileal water and electrolyte absorption in normal human subjects.
Topics: Adult; Aminosalicylic Acids; Bicarbonates; Chlorides; Dose-Response Relationship, Drug; Glucose; Humans; Ileum; Intestinal Absorption; Jejunum; Middle Aged; Potassium; Sodium; Sulfasalazine; Water | 1991 |
The effects of sulfasalazine metabolites on hemoglobin-catalyzed lipid peroxidation.
Topics: Aminosalicylic Acids; Free Radical Scavengers; Hemoglobins; Hydrogen Peroxide; Hydrolysis; Lipid Peroxidation; Phospholipids; Spectrophotometry, Ultraviolet; Sulfasalazine | 1991 |
Modulation of arachidonic acid metabolism by olsalazine and other aminosalicylates in leukocytes.
Topics: Aminosalicylic Acids; Arachidonic Acid; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes, Mononuclear; Leukotrienes; Mesalamine; Neutrophils; Prostaglandins; Sulfasalazine | 1991 |
Scavenger effect of sulphasalazine (SASP), 5-aminosalicylic acid (5-ASA), and olsalazine (OAZ)
Topics: Aminosalicylic Acids; Free Radicals; Humans; Mesalamine; Neutrophils; Sulfasalazine; Superoxides | 1990 |
Azodisalicylate (Dipentum)-induced hepatitis?
Topics: Aged; Aminosalicylic Acids; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Diverticulitis, Colonic; Female; Humans; Liver; Sulfasalazine | 1989 |
Sulfasalazine-induced impotence: a beneficial resolution with olsalazine?
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Erectile Dysfunction; Humans; Male; Middle Aged; Sulfasalazine | 1989 |
Disposition of disodium azodisalicylate in healthy subjects. A possible new drug for inflammatory bowel disease.
Topics: Administration, Oral; Aminosalicylic Acids; Crohn Disease; Half-Life; Humans; Kinetics; Mesalamine; Sulfapyridine; Sulfasalazine | 1985 |
Disodium azodisalicylate. American College of Gastroenterology Committee on FDA-Related Matters.
Topics: Aminosalicylic Acids; Chemical Phenomena; Chemistry; Colitis, Ulcerative; Humans; Sulfasalazine | 1985 |
In vitro effects of sulphasalazine, azodisal sodium, and their metabolites on Clostridium difficile and some other faecal bacteria.
Topics: Aminosalicylic Acids; Bacteroides; Clostridium; Enterococcus faecalis; Escherichia coli; Feces; Peptostreptococcus; Sulfasalazine | 1985 |
Sulphasalazine and derivatives, natural killer activity and ulcerative colitis.
Topics: Aminosalicylic Acids; Catechols; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Indomethacin; Killer Cells, Natural; Lipoxygenase Inhibitors; Masoprocol; Mesalamine; Monocytes; Sulfapyridine; Sulfasalazine | 1985 |
Effect of azodisal sodium on the distribution of a transit marker in the small bowel of the fasted rat.
Topics: Aminosalicylic Acids; Animals; Gastrointestinal Motility; Intestine, Small; Male; Mesalamine; Prostaglandins; Rats; Rats, Inbred Strains; Sulfasalazine; Time Factors | 1986 |
Azodisalicylate (azodisal sodium) causes intestinal secretion. Comparative study of the effect of azodisalicylate, sulfasalazine, 5-aminosalicylic acid and sulfapyridine on the water and electrolyte transfer and the morphology of the rat ileum and colon i
Topics: Aminosalicylic Acids; Animals; Colitis, Ulcerative; Colon; Ileum; Intestinal Absorption; Intestinal Mucosa; Mesalamine; Rats; Rats, Inbred Strains; Sulfapyridine; Sulfasalazine | 1987 |
Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine.
Topics: Aminosalicylic Acids; Antigen-Antibody Complex; Exocytosis; Humans; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfapyridine; Sulfasalazine; Superoxides | 1987 |
Sulfasalazine lung. Desensitization to sulfasalazine and treatment with acrylic coated 5-ASA and azodisalicylate.
Topics: Adult; Aminosalicylic Acids; Bronchiolitis Obliterans; Colitis, Ulcerative; Desensitization, Immunologic; Humans; Male; Mesalamine; Pulmonary Eosinophilia; Pulmonary Fibrosis; Sulfasalazine | 1987 |
Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia.
Topics: Adult; Aminosalicylic Acids; Colitis; Crohn Disease; Humans; Male; Pulmonary Eosinophilia; Sulfasalazine | 1988 |
Disodium azodisalicylate and sulfasalazine.
Topics: Aminosalicylic Acids; Drug Hypersensitivity; Humans; Pancreatitis; Sulfasalazine | 1988 |
Olsalazine and sulfasalazine allergy.
Topics: Aminosalicylic Acids; Drug Hypersensitivity; Humans; Sulfasalazine | 1988 |
Pharmacokinetics of olsalazine and its metabolites.
Topics: Acetylation; Aminosalicylic Acids; Animals; Dogs; Enterohepatic Circulation; Half-Life; Humans; Intestinal Absorption; Sulfasalazine | 1988 |
Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Female; Humans; Male; Mesalamine; Sulfasalazine | 1988 |
Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid.
Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Chemotaxis; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Macrophages; Male; Mesalamine; Middle Aged; Sulfasalazine | 1988 |
Determination of sodium azodisalicylate, salazosulphapyridine and their metabolites in serum, urine and faeces by high-performance liquid chromatography.
Topics: Aminosalicylic Acids; Chromatography, High Pressure Liquid; Feces; Humans; Sulfasalazine | 1984 |
Colonic azodisalicylate metabolism determined by in vivo dialysis in healthy volunteers and patients with ulcerative colitis.
Topics: Adult; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colon; Feces; Female; Humans; Male; Middle Aged; Sulfasalazine | 1984 |
Effects of sulphasalazine and disodium azodisalicylate on colonic PGE2 concentrations determined by equilibrium in vivo dialysis of faeces in patients with ulcerative colitis and healthy controls.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Colon; Dialysis; Dinoprostone; Feces; Female; Humans; Male; Middle Aged; Prostaglandins E; Sulfasalazine; Water | 1984 |
Pancreatitis associated with olsalazine and sulfasalazine in children with ulcerative colitis.
Topics: Acute Disease; Adolescent; Aminosalicylic Acids; Amylases; Child; Colitis, Ulcerative; Female; Humans; Lipase; Male; Methylprednisolone; Pancreatitis; Sulfasalazine | 1994 |
Ischemia reperfusion damage in the gut and its treatment with drugs of the aminosalicylic acid group.
Topics: Aminosalicylic Acids; Animals; Benzaldehydes; Glutathione; Glutathione Disulfide; Hydrazones; Intestinal Mucosa; Intestines; Male; Mesalamine; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Sulfasalazine; Thiobarbituric Acid Reactive Substances | 1994 |
Desensitization to sulfasalazine.
Topics: Aminosalicylic Acids; Child; Drug Hypersensitivity; Humans; Inflammatory Bowel Diseases; Stevens-Johnson Syndrome; Sulfasalazine | 1993 |
Effect of 5-aminosalicylic acid and analogous substances on superoxide generation and intracellular free calcium in human neutrophilic granulocytes.
Topics: Aminosalicylic Acids; Calcium; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfapyridine; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Sulphasalazine, olsalazine and sulphapyridine induce mitogenic actions in the rat intestinal epithelium.
Topics: Aminosalicylic Acids; Animals; Colon; Ileum; Intestinal Mucosa; Jejunum; Male; Mitogens; Rats; Sulfapyridine; Sulfasalazine | 1997 |
Efficacy of treatment for ulcerative colitis.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Mesalamine; Sulfasalazine | 1998 |
Experimental colitis induced by dextran sulphate sodium in mice: beneficial effects of sulphasalazine and olsalazine.
Topics: Aminosalicylic Acids; Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Mice; Mice, Inbred BALB C; Mice, Nude; Outcome Assessment, Health Care; Sulfasalazine; Survival Analysis; Treatment Outcome | 1998 |
Glomerular and tubular renal functions after long-term medication of sulphasalazine, olsalazine, and mesalazine in patients with ulcerative colitis.
Topics: Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Female; Gastrointestinal Agents; Humans; Kidney Diseases; Kidney Function Tests; Male; Mesalamine; Middle Aged; Retrospective Studies; Single-Blind Method; Sulfasalazine; Survivors | 2000 |
The effect of 5-aminosalicylic acid-containing drugs on sulfide production by sulfate-reducing and amino acid-fermenting bacteria.
Topics: Amino Acids; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Desulfovibrio; Feces; Fermentation; Fusobacterium; Humans; In Vitro Techniques; Inflammatory Bowel Diseases; Mesalamine; Phenylhydrazines; Sulfasalazine; Sulfides | 2003 |
Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis, Ulcerative; Diarrhea; Disease Models, Animal; Gastrointestinal Agents; Ileum; Mesalamine; Phenylhydrazines; Prodrugs; Rabbits; Random Allocation; Sulfasalazine; Tissue Culture Techniques | 2005 |
Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis.
Topics: Adult; Aminosalicylic Acids; Case-Control Studies; Chemoprevention; Chronic Disease; Colitis, Ulcerative; Colorectal Neoplasms; Female; Humans; Logistic Models; Male; Middle Aged; Precancerous Conditions; Sulfasalazine | 2006 |
High thiopurine metabolite concentrations associated with lymphopenia in inflammatory bowel disease (IBD) pediatric patients receiving aminosalicylates combined with azathioprine.
Topics: Adolescent; Aminosalicylic Acids; Azathioprine; Biotransformation; Child; Child, Preschool; Drug Therapy, Combination; Erythrocytes; Female; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lymphopenia; Male; Mesalamine; Purines; Salicylates; Sulfasalazine | 2010 |