Page last updated: 2024-09-04

olmesartan and sulpiride

olmesartan has been researched along with sulpiride in 2 studies

Compound Research Comparison

Studies (olmesartan)	Trials (olmesartan)	Recent Studies (post-2010) (olmesartan)	Studies (sulpiride)	Trials (sulpiride)	Recent Studies (post-2010) (sulpiride)
841	185	554	4,152	427	635

Protein Interaction Comparison

Protein	Taxonomy	sulpiride (IC50)
Carbonic anhydrase 1	Homo sapiens (human)	1.2
Carbonic anhydrase 2	Homo sapiens (human)	0.04
Alpha-2A adrenergic receptor	Homo sapiens (human)	2.019
D(2) dopamine receptor	Homo sapiens (human)	0.0858
D(3) dopamine receptor	Homo sapiens (human)	0.2651
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	0.2215
Carbonic anhydrase 4	Bos taurus (cattle)	0.62
D(2) dopamine receptor	Canis lupus familiaris (dog)	0.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1

Other Studies

2 other study(ies) available for olmesartan and sulpiride

Article	Year
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013

Article

Year

Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.

Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012

Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.

Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013