Page last updated: 2024-09-04

olmesartan and probenecid

olmesartan has been researched along with probenecid in 4 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(probenecid)
Trials
(probenecid)
Recent Studies (post-2010) (probenecid)
8411855543,664292375

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)probenecid (IC50)
Solute carrier family 22 member 8Mus musculus (house mouse)3.02
Solute carrier family 22 member 6Homo sapiens (human)6.85
Solute carrier family 22 member 8Homo sapiens (human)6.965
Solute carrier family 22 member 8Rattus norvegicus (Norway rat)6.03

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Ekins, S; Williams, AJ; Xu, JJ1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Adachi, M; Adachi, Y; Hu, Z; Kamiyama, E; Kondo, T; Kusuhara, H; Maeda, K; Nakazawa, H; Okano, T; Schuetz, JD; Shiroyanagi, Y; Sugiyama, D; Sugiyama, Y; Yamada, A1

Reviews

1 review(s) available for olmesartan and probenecid

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

3 other study(ies) available for olmesartan and probenecid

ArticleYear
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:12

    Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Dogs; Dose-Response Relationship, Drug; Estrone; Female; Hepatocytes; Humans; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Membrane Transport Proteins; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Olmesartan Medoxomil; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Probenecid; Prodrugs; Protein Binding; Protein Isoforms; Sincalide; Solute Carrier Organic Anion Transporter Family Member 1B3; Tetrazoles; Transfection

2007