Page last updated: 2024-09-04

olmesartan and nicardipine

olmesartan has been researched along with nicardipine in 2 studies

Compound Research Comparison

Studies (olmesartan)	Trials (olmesartan)	Recent Studies (post-2010) (olmesartan)	Studies (nicardipine)	Trials (nicardipine)	Recent Studies (post-2010) (nicardipine)
841	185	554	2,646	444	312

Protein Interaction Comparison

Protein	Taxonomy	nicardipine (IC50)
Bile salt export pump	Homo sapiens (human)	8.314
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	8
ATP-dependent translocase ABCB1	Homo sapiens (human)	4.2992
Cytochrome P450 3A4	Homo sapiens (human)	0.42
Cytochrome P450 2C9	Homo sapiens (human)	1.69
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	2.5
Cytochrome P450 2J2	Homo sapiens (human)	1.69
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	4.925
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	4.8

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Imai, K; Tsunoda, M; Yamagishi, M; Yanagisawa, T	1

Other Studies

2 other study(ies) available for olmesartan and nicardipine

Article	Year
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice. Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:4 Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Heart Rate; Imidazoles; Luminescence; Male; Mice; Mice, Inbred C57BL; Nicardipine; Nitroprusside; Oxalates; Reproducibility of Results; Sensitivity and Specificity; Tetrazoles; Time Factors	2009

Article

Year

Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.

Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013

Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice.

Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:4

Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Heart Rate; Imidazoles; Luminescence; Male; Mice; Mice, Inbred C57BL; Nicardipine; Nitroprusside; Oxalates; Reproducibility of Results; Sensitivity and Specificity; Tetrazoles; Time Factors

2009