Page last updated: 2024-09-04

olmesartan and mocetinostat

olmesartan has been researched along with mocetinostat in 5 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(mocetinostat)
Trials
(mocetinostat)
Recent Studies (post-2010) (mocetinostat)
84118555421,7353908,606

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Araújo, AA; de Castro Brito, GA; do Socorro Costa Feitosa Alves, M; Fernandes de Araújo, R; Lopes de Souza, G; Lourenço, Y; Sabóia Aragão, K; Souza, TO; Xavier de Medeiros, CA1
Bin, J; Cao, S; Chen, B; Fu, Y; Huang, Q; Huang, X; Kitakaze, M; Liao, Y; Lu, D; Xu, D; Zhang, J1
D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM1
de Araújo Júnior, RF; de Araújo, AA; de Medeiros, CA; de Menezes, MS; Guerra, GC1

Trials

1 trial(s) available for olmesartan and mocetinostat

ArticleYear
Olmesartan Combined With Amlodipine on Oxidative Stress Parameters in Type 2 Diabetics, Compared With Single Therapies: A Randomized, Controlled, Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:13

    Topics: Adult; Amlodipine; Antihypertensive Agents; Aryldialkylphosphatase; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Isoprostanes; Male; Oxidative Stress; Peroxidase; Tetrazoles

2016

Other Studies

4 other study(ies) available for olmesartan and mocetinostat

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Olmesartan decreases IL-1β and TNF-α levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:10

    Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Gingiva; Imidazoles; Interleukin-1beta; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Osteoprotegerin; Periodontitis; Peroxidase; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Tetrazoles; Tumor Necrosis Factor-alpha

2013
Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53.
    British journal of pharmacology, 2014, Volume: 171, Issue:15

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Cells, Cultured; Fibroblasts; Growth Differentiation Factor 15; Heart Rupture; Hypoxia; Imidazoles; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Peroxidase; Tetrazoles; Tumor Suppressor Protein p53

2014
Olmesartan Prevented Intra-articular Inflammation Induced by Zymosan in Rats.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:11

    Topics: Alanine Transaminase; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Arthritis, Experimental; Aspartate Aminotransferases; Creatinine; Cyclooxygenase 2; Glutathione; Glutathione Peroxidase; Imidazoles; Interleukin-17; Leukocyte Count; Male; Malondialdehyde; Peroxidase; Rats, Wistar; Superoxide Dismutase; Synovial Membrane; Tetrazoles; Tumor Necrosis Factor-alpha; Urea; Zymosan

2016