Page last updated: 2024-09-04

olmesartan and losartan

olmesartan has been researched along with losartan in 39 studies

Compound Research Comparison

Studies (olmesartan)	Trials (olmesartan)	Recent Studies (post-2010) (olmesartan)	Studies (losartan)	Trials (losartan)	Recent Studies (post-2010) (losartan)
841	185	554	7,231	1,245	2,118

Protein Interaction Comparison

Protein	Taxonomy	losartan (IC50)
Bile salt export pump	Homo sapiens (human)	9.01
Cytochrome P450 2C9	Homo sapiens (human)	2.882
Angiotensin-converting enzyme	Homo sapiens (human)	0.019
Atrial natriuretic peptide receptor 3	Homo sapiens (human)	0.0018
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.019
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0247
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0234
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	0.0032
Type-1 angiotensin II receptor	Homo sapiens (human)	0.047
Type-1 angiotensin II receptor	Oryctolagus cuniculus (rabbit)	0.025
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0118
Type-2 angiotensin II receptor	Homo sapiens (human)	0.019
Platelet glycoprotein VI	Homo sapiens (human)	4
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	1.1481
Type-1 angiotensin II receptor	Cavia porcellus (domestic guinea pig)	0.018
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	0.2884

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.56)	18.2507
2000's	11 (28.21)	29.6817
2010's	23 (58.97)	24.3611
2020's	4 (10.26)	2.80

Authors

Authors	Studies
Amemiya, Y; Fujimoto, K; Furukawa, Y; Ikeda, M; Kanazaki, T; Kitahara, Y; Koike, H; Miyamoto, S; Mizuno, M; Sada, T; Shimoji, Y; Yanagisawa, H	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ekins, S; Williams, AJ; Xu, JJ	1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR	1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM	1
Foster, H; Foster, R; Philippou, H; Wilson, C	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Iwanaga, T; Maeda, T; Ogihara, T; Sato, M; Tamai, I	1
Mitsuyama, S	1
Fujino, M; Imaizumi, S; Kanazawa, T; Karnik, SS; Kiya, Y; Matsuo, Y; Miura, S; Saku, K	1
Hamamoto, Y; Honjo, S; Ikeda, H; Koshiyama, H; Nabe, K; Wada, Y	1
Kuji, T; Masuda, S; Okano, Y; Tamura, K; Tochikubo, O; Umemura, S	1
Falvey, H; Lowy, A; Müller, E; Nixon, RM	1
Akazawa, H; Ito, K; Komuro, I; Kudo, Y; Liao, CH; Miura, S; Qin, Y; Saku, K; Yamamoto, R; Yasuda, N	1
Harada, N; Okajima, K; Shimozawa, N	1
Bouley, R; Brown, D; Ingelfinger, JR; Jung, FF; Kobori, H; Lu, HA; Nunes, P; Palomino, Z; Sabolic, I; Shum, WW; Tang, SS	1
Masuda, S; Okano, Y; Ozawa, M; Tamura, K; Tochikubo, O; Umemura, S	1
Burnier, M; Coltamai, L; Maillard, M; Simon, A; Vogt, B	1
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J	1
Fujiwara, N; Koide, H; Nakamura, T; Sato, E; Sugaya, T; Ueda, Y	1
Ge, J; Gong, H; Komuro, I; Li, L; Lin, L; Wu, J; Zhou, N; Zou, Y	1
Biskupiak, J; Qian, C; Quah, R; Ram, CV; Ramaswamy, K; Russo, PA; Ryan, A	1
Gandhi, HP; Giridhar, R; Naik, PP; Yadav, MR	1
Hasegawa, H; Kameda, Y; Kobayashi, Y; Komuro, I; Kubota, A; Takano, H	1
Corbalan, JJ; Jacob, RF; Jacoby, A; Kubant, R; Louka, F; Malinski, T; Mason, RP	1
Aksak, S; Albayrak, A; Albayrak, F; Gundogdu, C; Halici, Z; Karakus, E; Kiki, I; Ozturk, B; Polat, B; Sipal, S	1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T	1
Allen, RR; Ghushchyan, V; Kaila, S; Nair, KV; Saseen, JJ	1
Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC	1
Komano, H; Liu, J; Liu, S; Maeda, T; Tanabe, C; Zou, K	1
Kawabata, Y; Nakagawa, S; Suzuki, E; Takahashi, H; Uehara, Y; Wu, Y	1
Asayama, K; Haga, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Mano, N; Metoki, H; Murakami, T; Obara, T; Ohkubo, T; Satoh, M	1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G	1
Busby, J; Cardwell, CR; Hughes, C; Johnston, BT; McMenamin, Ú; Spence, A	1
Guo, CX; Li, X; Liu, JY; Liu, SK; Liu, ZQ; Luo, M; Pei, Q; Xie, P; Yang, GP; Yin, JY; Zheng, Y; Zhou, HH	1
Jóźwiak, K; Kocki, T; Targowska-Duda, KM; Turski, WA; Wnorowski, A; Zakrocka, I	1
Kim, H; Kim, HS; Kim, JH; Lee, SH	1

Reviews

3 review(s) available for olmesartan and losartan

Article	Year
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan	2010
[ARB: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects]. Nihon rinsho. Japanese journal of clinical medicine, 2007, May-28, Volume: 65 Suppl 5 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Contraindications; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan	2007
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach. International journal of clinical practice, 2009, Volume: 63, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2009

Trials

7 trial(s) available for olmesartan and losartan

Article	Year
Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes. Diabetes research and clinical practice, 2009, Volume: 83, Issue:1 Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan	2009
Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL. Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:3 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Autonomic Nervous System; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Health Surveys; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Telmisartan; Tetrazoles; Valine; Valsartan	2009
Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life. Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:8 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Sympathetic Nervous System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2009
Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans. Journal of hypertension, 2010, Volume: 28, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Kidney Tubules; Losartan; Single-Blind Method; Tetrazoles; Valine; Valsartan	2010
Renoprotective Effects of Various Angiotensin II Receptor Blockers in Patients with Early-Stage Diabetic Nephropathy. Kidney & blood pressure research, 2010, Volume: 33, Issue:3 Topics: Adult; Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fatty Acid-Binding Proteins; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Treatment Outcome	2010
Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:2 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Hypertension; Imidazoles; Japan; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan	2012
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate. Blood pressure, 2013, Volume: 22 Suppl 1 Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan	2013

Other Studies

29 other study(ies) available for olmesartan and losartan

Article	Year
Nonpeptide angiotensin II receptor antagonists: synthesis, biological activities, and structure-activity relationships of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Acetylation; Adrenal Cortex; Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Availability; Cattle; Imidazoles; In Vitro Techniques; Kinetics; Male; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Rats; Rats, Wistar; Receptors, Angiotensin; Structure-Activity Relationship	1996
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5 Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells. European journal of medicinal chemistry, 2020, Jun-01, Volume: 195 Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan	2020
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21 Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis	2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Female; Imidazoles; Losartan; Organic Anion Transporters; Organic Cation Transport Proteins; Pyrazinamide; Tetrazoles; Uric Acid; Valine; Valsartan; Xenopus laevis	2007
Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state. Molecular endocrinology (Baltimore, Md.), 2008, Volume: 22, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Binding Sites; Chlorocebus aethiops; Computer Simulation; COS Cells; Imidazoles; Losartan; Lysine; Molecular Structure; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptor, Angiotensin, Type 1; Serine; Structure-Activity Relationship; Tetrazoles; Valine; Valsartan	2008
Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation. Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:10 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Northern; Blotting, Western; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; In Vitro Techniques; Ligands; Losartan; Mutation; Myocytes, Cardiac; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA; Structure-Activity Relationship; Tetrazoles	2009
AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats. Translational research : the journal of laboratory and clinical medicine, 2009, Volume: 154, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ganglia, Spinal; Hypertension; Imidazoles; Insulin-Like Growth Factor I; Kidney; Losartan; Male; Myocardium; Nifedipine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Sensory Receptor Cells; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilator Agents	2009
Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression. American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 1; Cell Line, Transformed; Diuresis; Dose-Response Relationship, Drug; Drug Synergism; Hypertonic Solutions; Imidazoles; Kidney; Kidney Tubules, Proximal; Loop of Henle; Losartan; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Chloride; Tetrazoles; Time Factors	2009
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters. Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:2-3 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes	2010
Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice. Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:12 Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Echocardiography; Gene Expression; Hemodynamics; Imidazoles; Losartan; Male; Mice; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2010
Blood pressure outcomes in patients receiving angiotensin II receptor blockers in primary care: a comparative effectiveness analysis from electronic medical record data. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Black or African American; Blood Pressure; Diabetes Mellitus; Electronic Health Records; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Obesity; Primary Health Care; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People; Young Adult	2011
Revelation on the potency of α(1) -blockers - parallel blockade of angiotensin II receptor: a new finding. Pharmaceutical biology, 2012, Volume: 50, Issue:4 Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Doxazosin; Imidazoles; In Vitro Techniques; Losartan; Male; Molecular Structure; Prazosin; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents	2012
Effects of angiotensin receptor blockers on endothelial nitric oxide release: the role of eNOS variants. British journal of clinical pharmacology, 2012, Volume: 74, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Cells, Cultured; Female; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Losartan; Nitric Oxide; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide; Telmisartan; Tetrazoles; Umbilical Veins; Valine; Valsartan; Vasodilation	2012
Comparative study of three angiotensin II type 1 receptor antagonists in preventing liver fibrosis in diabetic rats: stereology, histopathology, and electron microscopy. Journal of molecular histology, 2012, Volume: 43, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Diabetes Mellitus, Experimental; Imidazoles; Liver Cirrhosis; Losartan; Male; Microscopy, Electron; Rats; Tetrazoles; Valine; Valsartan	2012
Maintaining goal blood pressures after switching from olmesartan to other angiotensin receptor blockers. Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:12 Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Substitution; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan	2013
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:5 Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2014
Differential effects of angiotensin II receptor blockers on Aβ generation. Neuroscience letters, 2014, May-01, Volume: 567 Topics: Amyloid beta-Peptides; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Fibroblasts; Imidazoles; Losartan; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Phosphatidylinositol 3-Kinases; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Tetrazoles; Valine; Valsartan	2014
The angiotensin II receptor antagonist, losartan, enhances regulator of G protein signaling 2 mRNA expression in vascular smooth muscle cells of Wistar rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2016, Volume: 39, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Cells, Cultured; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Rats; Rats, Wistar; RGS Proteins; RNA, Messenger; Signal Transduction; Tetrazoles; Up-Regulation	2016
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements. Journal of hypertension, 2016, Volume: 34, Issue:6 Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan	2016
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles. The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23 Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents	2016
Angiotensin receptor blocker use and gastro-oesophageal cancer survival: a population-based cohort study. Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Child; Child, Preschool; Cohort Studies; Diabetic Neuropathies; Esophageal Neoplasms; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Infant; Infant, Newborn; Losartan; Male; Middle Aged; Registries; Stomach Neoplasms; Survival Analysis; Tetrazoles; Young Adult	2018
Repaglinide-irbesartan drug interaction: effects of SLCO1B1 polymorphism on repaglinide pharmacokinetics and pharmacodynamics in Chinese population. European journal of clinical pharmacology, 2018, Volume: 74, Issue:8 Topics: Adult; Asian People; Biphenyl Compounds; Blood Glucose; Carbamates; Cells, Cultured; China; Dose-Response Relationship, Drug; Drug Interactions; Genotype; Healthy Volunteers; Humans; Imidazoles; Irbesartan; Liver-Specific Organic Anion Transporter 1; Losartan; Male; Piperidines; Polymorphism, Single Nucleotide; Tetrazoles; Valsartan; Young Adult	2018
Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kynurenic Acid; Losartan; Male; Rats, Wistar; Telmisartan; Tetrazoles; Transaminases; Valsartan	2019
Comparative analysis of the efficacy of angiotensin II receptor blockers for uric acid level change in asymptomatic hyperuricaemia. Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:6 Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cohort Studies; Female; Humans; Hyperuricemia; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Retrospective Studies; Tetrazoles; Time Factors; Uric Acid	2020