olmesartan has been researched along with hydrochlorothiazide in 64 studies
| Studies (olmesartan) | Trials (olmesartan) | Recent Studies (post-2010) (olmesartan) | Studies (hydrochlorothiazide) | Trials (hydrochlorothiazide) | Recent Studies (post-2010) (hydrochlorothiazide) |
|---|---|---|---|---|---|
| 841 | 185 | 554 | 6,921 | 2,165 | 1,262 |
| Protein | Taxonomy | olmesartan (IC50) | hydrochlorothiazide (IC50) |
|---|---|---|---|
| Carbonic anhydrase 2 | Homo sapiens (human) | 5.4954 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (17.19) | 29.6817 |
| 2010's | 49 (76.56) | 24.3611 |
| 2020's | 4 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Laeis, P; Rump, LC; Sellin, L; Stegbauer, J | 1 |
| Böhm, M; Ewald, S | 1 |
| Dubiel, R; Izzo, JL; Neutel, JM; Silfani, T; Walker, F | 1 |
| Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A | 1 |
| Ruilope, LM | 1 |
| Dominiczak, AF; Fields, L; Graham, D; Hamilton, CA; Koh-Tan, HH; McBride, MW; Nicoll, G; Young, B | 1 |
| Eguchi, K; Ishikawa, J; Kario, K; Matsui, Y; Miyashita, H; O'Rourke, MF; Shimada, K | 1 |
| Blacher, J; Protogerou, A; Safar, ME | 1 |
| Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K | 1 |
| Kereiakes, DJ; Neutel, JM; Shojaee, A; Stoakes, KA; Waverczak, WF; Xu, J | 1 |
| Burnier, M; Coltamai, L; Maillard, M; Simon, A; Vogt, B | 1 |
| Feng, S; Hu, P; Jiang, J; Liu, D; Wang, P | 1 |
| Comi-Diaz, C; Martinez-Martin, FJ; Pedrianes-Martin, P; Peiro-Martinez, I; Rodriguez-Rosas, H; Soriano-Perera, P | 1 |
| Eguchi, K; Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K | 1 |
| Kashihara, N; Nagasu, H; Sasaki, T; Satoh, M; Tomita, N; Yorimitsu, D | 1 |
| Makris, T; Stefanadis, C; Thomopoulos, C; Tsioufis, C | 1 |
| McInnes, GT | 1 |
| Palatini, P | 1 |
| Graff, A; Hsueh, WA; Jones, CJ; Littlejohn, TJ; Nesbitt, SD; Neutel, JM; Qian, C; Shojaee, A; Waverczak, WF; Weir, MR | 1 |
| Narkiewicz, K | 1 |
| Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn Iii, T; Melino, M; Oparil, S | 1 |
| Ahbap, E; Basturk, T; Borlu, F; Damar, AB; Koc, Y; Mazi, E; Sakaci, T; Unsal, A | 1 |
| Hara, T; Hayden, MR; Hitomi, H; Ichimura, A; Ito, S; Kaifu, K; Kawachi, H; Kiyomoto, H; Kobori, H; Kohno, M; Matsumoto, S; Nishijima, Y; Nishiyama, A; Ohsaki, H; Sofue, T; Sowers, JR; Urushihara, M; Whaley-Connell, A | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A | 1 |
| Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn, T; Melino, M; Oparil, S | 2 |
| Hoshide, S; Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K | 1 |
| Bilo, G; Parati, G | 1 |
| Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K | 1 |
| Bakris, GL; Cushman, WC; Kupfer, S; Lloyd, E; Roberts, A; Sica, D; Weber, MA; White, WB | 2 |
| Maa, JF; Neutel, J; Shojaee, A | 1 |
| Ammentorp, B; Christian Rump, L; Laeis, P; Volpe, M | 1 |
| Gumustas, M; Kurbanoglu, S; Ozkan, SA | 1 |
| Paneni, F; Passerini, J; Tocci, G; Volpe, M | 1 |
| de la Sierra, A; Volpe, M | 1 |
| Bramlage, P; Fronk, EM; Ketelhut, R; Schmieder, RE; Wolf, WP; Zemmrich, C | 1 |
| Chrysant, SG | 1 |
| Amaya, N; Arakawa, K; Fukuoka, Y; Ishida, K; Lee, JD; Morishita, T; Nakano, A; Tada, H; Uzui, H | 1 |
| de la Sierra, A; Kreutz, R; Laurent, S; Manolis, AJ; Volpe, M | 1 |
| Bramlage, P; Fronk, EM; Ketelhut, R; Schmieder, RE; Smolnik, R; Wolf, WP; Zemmrich, C | 1 |
| Ammentorp, B; de la Sierra, A; Laeis, P; Volpe, M | 1 |
| O'Brien, E | 1 |
| Ammentorp, B; de la Sierra, A; Kreutz, R; Laeis, P | 1 |
| Angeloni, E; Lombardo, P; Pirelli, M; Refice, S; Vitaterna, A | 1 |
| Bramlage, P; Fronk, EM; Schmieder, RE; Smolnik, R; Sutton, G; Wolf, WP | 1 |
| Schlimpert, V | 1 |
| Ahn, Y; Bae, JH; Jung, HW; Kang, DH; Kim, CH; Kim, KI; Park, CG | 1 |
| Brazier, JE; Guest, JF; Haag, U; Marques da Silva, P; Soro, M | 1 |
| Abdelhameed, AS; Bakheit, AH; Darwish, HW | 1 |
| Douros, A; Kreutz, R; Scholze, J | 1 |
| van der Merwe, WM | 1 |
| Bakris, GL; Cushman, WC; Ferdinand, KC; Lloyd, E; Weber, MA; White, WB; Wu, J | 1 |
| Ahn, KT; Cho, BR; Kim, BJ; Kim, DK; Lee, SY; Lee, WS; Park, JI; Sung, J | 1 |
| Burnier, M; Redon, J; Volpe, M | 1 |
| Hong, JH; Hyun, D; Kim, GH; Kim, HL; Kim, W; Lim, S; Min, KW; Oh, J; Park, SD; Shin, J | 1 |
5 review(s) available for olmesartan and hydrochlorothiazide
| Article | Year |
|---|---|
Clinical efficacy and safety of olmesartan/hydrochlorothiazide combination therapy in patients with essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Practice Guidelines as Topic; Severity of Illness Index; Tetrazoles; Time Factors; Treatment Outcome | 2008 |
Angiotensin II receptor blocker combinations: from guidelines to clinical practice.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antineoplastic Agents; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Practice Guidelines as Topic; Tetrazoles | 2012 |
Triple combination therapy to improve blood pressure control: experience with olmesartan-amlodipine-hydrochlorothiazide therapy.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles | 2012 |
Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD.
Topics: Age Factors; Amlodipine; Cardiovascular Diseases; Diabetes Complications; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Renal Insufficiency, Chronic; Tetrazoles | 2013 |
Single-Pill Combination with Three Antihypertensive Agents to Improve Blood Pressure Control in Hypertension: Focus on Olmesartan-Based Combinations.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Olmesartan Medoxomil | 2023 |
28 trial(s) available for olmesartan and hydrochlorothiazide
| Article | Year |
|---|---|
Adding hydrochlorothiazide to olmesartan dose dependently improves 24-h blood pressure and response rates in mild-to-moderate hypertension.
Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Tetrazoles; Treatment Outcome | 2005 |
Blood pressure reduction with olmesartan in mild-to-moderate essential hypertension: a planned interim analysis of an open label sub-study in German patients.
Topics: Adolescent; Adult; Aged; Angiotensin Receptor Antagonists; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2006 |
Efficacy and safety of treating stage 2 systolic hypertension with olmesartan and olmesartan/HCTZ: results of an open-label titration study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome | 2007 |
Effect of delapril/manidipine vs olmesartan/ hydrochlorothiazide combination on insulin sensitivity and fibrinogen in obese hypertensive patients.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Female; Fibrinogen; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Insulin Resistance; Male; Middle Aged; Nitrobenzenes; Obesity; Piperazines; Tetrazoles | 2008 |
Effects of manidipine/delapril versus olmesartan/hydrochlorothiazide combination therapy in elderly hypertensive patients with type 2 diabetes mellitus.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus, Type 2; Dihydropyridines; Diuretics; Drug Combinations; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypotension, Orthostatic; Imidazoles; Indans; Male; Nitrobenzenes; Piperazines; Posture; Prospective Studies; Tetrazoles | 2008 |
Differential effects between a calcium channel blocker and a diuretic when used in combination with angiotensin II receptor blocker on central aortic pressure in hypertensive patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aorta; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Time Factors; Treatment Outcome | 2009 |
Effects of an olmesartan medoxomil based treatment algorithm on 24-hour blood pressure control in patients with hypertension and type 2 diabetes.
Topics: Aged; Algorithms; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Time Factors | 2010 |
Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Kidney Tubules; Losartan; Single-Blind Method; Tetrazoles; Valine; Valsartan | 2010 |
Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study.
Topics: Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Comorbidity; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Insulin Resistance; Intercellular Adhesion Molecule-1; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Vascular Cell Adhesion Molecule-1 | 2011 |
Association between aldosterone induced by antihypertensive medication and arterial stiffness reduction: the J-CORE study.
Topics: Aged; Aldosterone; Antihypertensive Agents; Aorta; Azetidinecarboxylic Acid; Blood Flow Velocity; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Imidazoles; Male; Pulsatile Flow; Tetrazoles; Vascular Resistance | 2011 |
A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixed-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Self Report; Tetrazoles; Titrimetry; Young Adult | 2011 |
24-hour efficacy and safety of Triple-Combination Therapy With Olmesartan, Amlodipine, and Hydrochlorothiazide: the TRINITY ambulatory blood pressure substudy.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors | 2011 |
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2012 |
Long-term efficacy and safety of triple-combination therapy with olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide for hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors | 2012 |
Combined effect of angiotensin II receptor blocker and either a calcium channel blocker or diuretic on day-by-day variability of home blood pressure: the Japan Combined Treatment With Olmesartan and a Calcium-Channel Blocker Versus Olmesartan and Diuretic
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Tetrazoles; Treatment Outcome | 2012 |
Association of changes in ambulatory arterial stiffness index and pulse wave velocity during antihypertensive treatment: the J-CORE study.
Topics: Aged; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness | 2012 |
Azilsartan medoxomil plus chlorthalidone reduces blood pressure more effectively than olmesartan plus hydrochlorothiazide in stage 2 systolic hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Black People; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Severity of Illness Index; Tetrazoles; Treatment Outcome; White People | 2012 |
Efficacy of amlodipine/olmesartan ± hydrochlorothiazide in patients uncontrolled on prior calcium channel blocker or angiotensin II receptor blocker monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Comorbidity; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2012 |
Triple-Combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in black and non-black study participants with hypertension: the TRINITY randomized, double-blind, 12-week, parallel-group study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2012 |
Efficacy and safety of triple antihypertensive therapy with the olmesartan/amlodipine/hydrochlorothiazide combination.
Topics: Adult; Aged; Aging; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Young Adult | 2012 |
Effects of combination therapy with olmesartan and azelnidipine on serum osteoprotegerin in patients with hypertension.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Biomarkers; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Matrix Metalloproteinase 2; Middle Aged; Osteoprotegerin; Prospective Studies; Tetrazoles | 2014 |
Open-label study assessing the long-term efficacy and safety of triple olmesartan/amlodipine/hydrochlorothiazide combination therapy for hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Time; Treatment Outcome | 2014 |
Efficacy and tolerability of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide: a subgroup analysis of patients stratified by hypertension severity, age, sex, and obesity.
Topics: Adult; Age Factors; Aged; Amlodipine; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Sex Factors; Tetrazoles | 2014 |
A multicenter, non-comparative study to evaluate the efficacy and safety of fixed-dose olmesartan/amlodipine in Korean patients with hypertension who are naïve or non-responders to anti-hypertensive monotherapy (ACE-HY study).
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Prospective Studies; Republic of Korea; Tetrazoles; Treatment Outcome | 2015 |
Health-related quality of life impact of a triple combination of olmesartan medoxomil, amlodipine besylate and hydrochlorotiazide in subjects with hypertension.
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Quality of Life; Tetrazoles; Treatment Outcome | 2015 |
A randomized titrate-to-target study comparing fixed-dose combinations of azilsartan medoxomil and chlorthalidone with olmesartan and hydrochlorothiazide in stage-2 systolic hypertension.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles | 2018 |
Comparison of Effectiveness of Azilsartan Medoxomil and Olmesartan in Blacks Versus Whites With Systemic Hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Black or African American; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles; United States; White People | 2018 |
Adherence to triple-component antihypertensive regimens is higher with single-pill than equivalent two-pill regimens: A randomized controlled trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome | 2021 |
31 other study(ies) available for olmesartan and hydrochlorothiazide
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure.
Topics: Acetylcysteine; Animals; Glutathione Transferase; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Kidney; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Systole; Tetrazoles | 2009 |
Central blood pressure under angiotensin and calcium channel blockade.
Topics: Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Imidazoles; Tetrazoles; Treatment Outcome | 2009 |
Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Brain; Electron Spin Resonance Spectroscopy; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Imidazoles; Male; NADPH Oxidases; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tetrazoles | 2009 |
Simultaneous quantitative determination of olmesartan and hydrochlorothiazide in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.
Topics: Antihypertensive Agents; Chromatography, Liquid; Humans; Hydrochlorothiazide; Imidazoles; Tandem Mass Spectrometry; Tetrazoles | 2010 |
Comparison of combination therapy of olmesartan plus azelnidipine or hydrochlorothiazide on renal and vascular damage in SHR/NDmcr-cp rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Dihydropyridines; Drug Therapy, Combination; Hydrochlorothiazide; Imidazoles; Kidney Diseases; Oxidative Stress; Rats; Rats, Inbred SHR; Tetrazoles; Vascular Diseases | 2011 |
The 'pyrrhic victory' of amlodipine over hydrochlorothiazide in the OLAS Study.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Body Mass Index; Comorbidity; Drug Therapy, Combination; Endpoint Determination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Life Style; Metabolic Syndrome; Tetrazoles; Treatment Outcome | 2011 |
The effect of antihypertensive agents in people at high risk of cardiovascular disease and diabetes: a view through smoke and mirrors.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Risk Factors; Tetrazoles; Treatment Outcome | 2011 |
Reduction of albuminuria with antihypertensive treatment: is more always better?
Topics: Albuminuria; Antihypertensive Agents; Azetidinecarboxylic Acid; Dihydropyridines; Humans; Hydrochlorothiazide; Imidazoles; Tetrazoles | 2011 |
Effect of Olmesartan on serum cystatin C levels in the patients with essential hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Cystatin C; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2011 |
Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Imidazoles; Juxtaglomerular Apparatus; Male; Membrane Proteins; Podocytes; Rats; Rats, Inbred OLETF; Reserpine; Tetrazoles | 2012 |
Calcium antagonist added to angiotensin receptor blocker: a recipe for reducing blood pressure variability?: evidence from day-by-day home blood pressure monitoring.
Topics: Azetidinecarboxylic Acid; Blood Pressure; Dihydropyridines; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Tetrazoles | 2012 |
[Hypertension: improved therapy adherence after switch to a fixed drug combinations].
Topics: Amlodipine; Antihypertensive Agents; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Drug Substitution; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Tetrazoles | 2012 |
Simultaneous estimation and validation of some binary mixtures of antihypertensive drugs by RP-LC methods using two new generation silica columns.
Topics: Antihypertensive Agents; Captopril; Chromatography, Reverse-Phase; Hydrochlorothiazide; Imidazoles; Indicators and Reagents; Silicon Dioxide; Solvents; Tetrazoles | 2013 |
Olmesartan-based therapies: an effective way to improve blood pressure control and cardiovascular protection.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles; Treatment Failure | 2013 |
[Hypertension. Goal: achieving target blood pressure with only 1 pill daily].
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Tetrazoles | 2013 |
Safety, tolerability, and efficacy of a fixed-dose combination of olmesartan 40 mg and hydrochlorothiazide 12.5/25 mg in daily practice.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Austria; Blood Pressure; Diuretics; Drug Combinations; Energy Metabolism; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Motor Activity; Tetrazoles; Time Factors; Treatment Outcome | 2013 |
ARB-based single-pill platform to guide a practical therapeutic approach to hypertensive patients.
Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Risk Factors; Tablets; Tetrazoles; Treatment Outcome | 2014 |
Clinical impact of patient adherence to a fixed-dose combination of olmesartan, amlodipine and hydrochlorothiazide.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Tetrazoles; Young Adult | 2014 |
[Hypertension. Guidelines recommend fixed combinations].
Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Guideline Adherence; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Randomized Controlled Trials as Topic; Tetrazoles | 2014 |
If I had resistant hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome | 2014 |
Single-pill combination therapy in the initial treatment of marked hypertension: a propensity-matched analysis.
Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Propensity Score; Ramipril; Retrospective Studies; Risk Factors; Telmisartan; Tetrazoles | 2015 |
Safety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Austria; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome | 2015 |
[Optimizing antihypertensive therapy].
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Randomized Controlled Trials as Topic; Tetrazoles | 2015 |
Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods.
Topics: Amlodipine; Calibration; Dosage Forms; Drug Combinations; Hydrochlorothiazide; Imidazoles; Least-Squares Analysis; Spectrophotometry; Tetrazoles | 2016 |
Single-Pill Triple Fixed Dose Combination Therapy with Single Component Drug Monitoring in Treatment-Resistant Hypertension: A Pilot Study.
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Resistance; Drug Substitution; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Pilot Projects; Tablets; Tetrazoles; Time Factors; Treatment Outcome | 2018 |
Treatment of hypertension in CKD patients with azilsartan/chlorthalidone vs olmesartan/hydrochlorothiazide.
Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Oxadiazoles; Renal Insufficiency, Chronic; Tetrazoles | 2018 |
Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Hypertension and Cardiovascular Risk Factors.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Female; Heart Disease Risk Factors; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Prospective Studies; Republic of Korea; Risk Factors; Tetrazoles | 2023 |