Compounds > olmesartan
Page last updated: 2024-09-04

olmesartan and fasudil

olmesartan has been researched along with fasudil in 3 studies

Compound Research Comparison

Studies
(olmesartan)		Trials
(olmesartan)		Recent Studies (post-2010)
(olmesartan)		Studies
(fasudil)		Trials
(fasudil)		Recent Studies (post-2010) (fasudil)
84118555496540552

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)fasudil (IC50)
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)2.28
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)2.28
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)2.28
Chain I, cAMP-dependent protein kinase inhibitor alphasynthetic construct2.28
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)2.28
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunitBos taurus (cattle)2.28
Chain I, cAMP-dependent protein kinase inhibitor alphasynthetic construct2.28
Rho-associated protein kinase 2Homo sapiens (human)0.5296
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)5
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)1.8042
C-C motif chemokine 2Homo sapiens (human)6.9183
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)4.58
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)4.58
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)4.58
Protein kinase C epsilon typeHomo sapiens (human)3
Rho-associated protein kinase 1Homo sapiens (human)1.1469
Myosin light chain kinase, smooth muscleHomo sapiens (human)3.6
Serine/threonine-protein kinase N1Homo sapiens (human)1.7
Serine/threonine-protein kinase N2Homo sapiens (human)1.8533
Rho-associated protein kinase 2Bos taurus (cattle)1.8042
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)1.9

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Higashi, K; Hyodo, N; Imakiire, T; Kikuchi, Y; Kushiyama, T; Miura, S; Oda, T; Suzuki, S; Yamada, M; Yamamoto, K1
Higashi, K; Kumagai, H; Kushiyama, T; Miura, S; Oda, T; Oshima, N; Sakurai, Y; Takechi, H; Uchida, T; Watanabe, A; Yamamoto, K1

Other Studies

3 other study(ies) available for olmesartan and fasudil

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats.
    The Journal of endocrinology, 2007, Volume: 192, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Enzyme Inhibitors; Glycated Hemoglobin; Imidazoles; Intracellular Signaling Peptides and Proteins; Kidney; Lipid Metabolism; Male; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Rats; Rats, Inbred OLETF; Rho Factor; rho-Associated Kinases; Signal Transduction; Tetrazoles

2007
Protective effects of Rho kinase inhibitor fasudil on rats with chronic kidney disease.
    American journal of physiology. Renal physiology, 2013, Jun-01, Volume: 304, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Enzyme Inhibitors; Hypercholesterolemia; Imidazoles; Kidney Glomerulus; Lectins, C-Type; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Membrane Proteins; Microscopy, Electron; Phenotype; Proteinuria; Rats; Receptors, Cell Surface; Renal Insufficiency, Chronic; rho-Associated Kinases; RNA, Messenger; Tetrazoles

2013