Page last updated: 2024-09-04

olmesartan and exp3174

olmesartan has been researched along with exp3174 in 4 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(exp3174)
Trials
(exp3174)
Recent Studies (post-2010) (exp3174)
8411855542362943

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)exp3174 (IC50)
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0013
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.0027
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0036
Type-1 angiotensin II receptorHomo sapiens (human)0.002
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.0075
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.0075

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amemiya, Y; Fujimoto, K; Furukawa, Y; Ikeda, M; Kanazaki, T; Kitahara, Y; Koike, H; Miyamoto, S; Mizuno, M; Sada, T; Shimoji, Y; Yanagisawa, H1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G1

Reviews

1 review(s) available for olmesartan and exp3174

ArticleYear
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan

2010

Other Studies

3 other study(ies) available for olmesartan and exp3174

ArticleYear
Nonpeptide angiotensin II receptor antagonists: synthesis, biological activities, and structure-activity relationships of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Acetylation; Adrenal Cortex; Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Availability; Cattle; Imidazoles; In Vitro Techniques; Kinetics; Male; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Rats; Rats, Wistar; Receptors, Angiotensin; Structure-Activity Relationship

1996
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents

2011
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
    The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23

    Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2016