olmesartan has been researched along with estrone in 6 studies
Studies (olmesartan) | Trials (olmesartan) | Recent Studies (post-2010) (olmesartan) | Studies (estrone) | Trials (estrone) | Recent Studies (post-2010) (estrone) |
---|---|---|---|---|---|
841 | 185 | 554 | 10,266 | 432 | 1,372 |
Protein | Taxonomy | olmesartan (IC50) | estrone (IC50) |
---|---|---|---|
Estrogen receptor | Homo sapiens (human) | 0.1261 | |
Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 6.589 | |
17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | 0.4134 | |
Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.301 | |
Estrogen receptor beta | Homo sapiens (human) | 0.3743 | |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 4 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Adachi, M; Adachi, Y; Hu, Z; Kamiyama, E; Kondo, T; Kusuhara, H; Maeda, K; Nakazawa, H; Okano, T; Schuetz, JD; Shiroyanagi, Y; Sugiyama, D; Sugiyama, Y; Yamada, A | 1 |
Kamiyama, E; Miura, S; Nakai, D; Okazaki, O; Sugiyama, D | 1 |
Owen, A; Riley, RJ; Soars, AC; Soars, MG; White, P; Williamson, B | 1 |
Fujibayashi, A; Maruyama, T; Nakashima, E; Nishimura, T; Noguchi, S; Tomi, M | 1 |
1 review(s) available for olmesartan and estrone
Article | Year |
---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
5 other study(ies) available for olmesartan and estrone
Article | Year |
---|---|
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Dogs; Dose-Response Relationship, Drug; Estrone; Female; Hepatocytes; Humans; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Membrane Transport Proteins; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Olmesartan Medoxomil; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Probenecid; Prodrugs; Protein Binding; Protein Isoforms; Sincalide; Solute Carrier Organic Anion Transporter Family Member 1B3; Tetrazoles; Transfection | 2007 |
Culture period-dependent change of function and expression of ATP-binding cassette transporters in Caco-2 cells.
Topics: Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Caco-2 Cells; Calcium Channel Blockers; Digoxin; Electric Conductivity; Estrone; Humans; Imidazoles; Leukotriene Antagonists; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Ochratoxins; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Tight Junctions; Time Factors; Verapamil | 2009 |
Dissecting the relative contribution of OATP1B1-mediated uptake of xenobiotics into human hepatocytes using siRNA.
Topics: Base Sequence; Cells, Cultured; Cytochrome P-450 CYP3A; Drug Interactions; Estrone; Female; Fluorobenzenes; Hepatocytes; Humans; Imidazoles; Liver-Specific Organic Anion Transporter 1; Male; Molecular Sequence Data; Organic Anion Transporters; Pyrimidines; Quinolines; RNA, Small Interfering; Rosuvastatin Calcium; Sulfonamides; Tetrazoles; Valine; Valsartan; Xenobiotics | 2013 |
Organic Anion Transporter 4-Mediated Transport of Olmesartan at Basal Plasma Membrane of Human Placental Barrier.
Topics: Angiotensin II Type 1 Receptor Blockers; Biological Transport; Cell Membrane; Chlorides; Dehydroepiandrosterone Sulfate; Estrone; Female; Humans; Imidazoles; Organic Anion Transporters; Placenta; Pregnancy; Sulfobromophthalein; Tetrazoles; Trophoblasts | 2015 |