Page last updated: 2024-09-04

olmesartan and captopril

olmesartan has been researched along with captopril in 11 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(captopril)
Trials
(captopril)
Recent Studies (post-2010) (captopril)
84118555410,3201,514890

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)captopril (IC50)
Leukotriene A-4 hydrolaseHomo sapiens (human)3.6
Angiotensin-converting enzyme Homo sapiens (human)0.084
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.0173
Succinyl-diaminopimelate desuccinylaseHaemophilus influenzae Rd KW203.3
Angiotensin-converting enzymeRattus norvegicus (Norway rat)0.1004
Beta-lactamase Pseudomonas aeruginosa5
Angiotensin-converting enzyme 2 Homo sapiens (human)0.011
Beta-lactamase class B VIM-2 Pseudomonas aeruginosa3.5

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Ekins, S; Williams, AJ; Xu, JJ1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Aso, Y; Inukai, T; Inukai, Y; Matsutomo, R; Nakamachi, T; Takahashi, K; Takanashi, K; Takebayashi, K; Wakabayashi, S; Yoshida, N1
Danser, AH; Krop, M; van Esch, JH1
Imai, K; Tsunoda, M; Yamagishi, M; Yanagisawa, T1
Celi, A; Cianchetti, S; Del Fiorentino, A; Pedrinelli, R1
Gumustas, M; Kurbanoglu, S; Ozkan, SA1
Adamcová, M; Arendášová, K; Aziriová, S; Bárta, A; Celec, P; Hrenák, J; Kamodyová, N; Krajčírovičová, K; Paulis, L; Rajkovičová, R; Repová, K; Simko, F1
Ding, Z; Ge, J; Gong, H; Jiang, G; Li, Y; Wang, S; Wang, X; Wu, J; Ye, Y; Yin, P; Yuan, J; Zhang, W; Zhou, J; Zou, Y1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G1

Reviews

1 review(s) available for olmesartan and captopril

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

10 other study(ies) available for olmesartan and captopril

ArticleYear
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers effectively and directly potentiate superoxide scavenging by polymorphonuclear leukocytes from patients with type 2 diabetes mellitus.
    The American journal of the medical sciences, 2005, Volume: 329, Issue:5

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Ascorbic Acid; Blood Glucose; Captopril; Diabetes Mellitus, Type 2; Female; Free Radical Scavengers; Humans; Imidazoles; In Vitro Techniques; Male; Middle Aged; Neutrophils; Superoxide Dismutase; Superoxides; Tetrazoles; Thiazepines

2005
Letter by Krop et al regarding article, "Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium".
    Circulation, 2006, Oct-24, Volume: 114, Issue:17

    Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Buffers; Captopril; Diabetes Complications; Diabetes Mellitus, Experimental; Diffusion; Free Radical Scavengers; Imidazoles; Kallikreins; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Perfusion; Rats; Renin-Angiotensin System; Ribosomal Protein S6 Kinases, 90-kDa; Species Specificity; Tetrazoles

2006
Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice.
    Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:4

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Heart Rate; Imidazoles; Luminescence; Male; Mice; Mice, Inbred C57BL; Nicardipine; Nitroprusside; Oxalates; Reproducibility of Results; Sensitivity and Specificity; Tetrazoles; Time Factors

2009
Aliskiren, a renin inhibitor, downregulates TNF-α-induced tissue factor expression in HUVECS.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2010, Volume: 11, Issue:4

    Topics: Amides; Captopril; Down-Regulation; Endothelial Cells; Fumarates; Humans; Imidazoles; Renin; Tetrazoles; Thromboplastin; Tumor Necrosis Factor-alpha; Umbilical Veins

2010
Simultaneous estimation and validation of some binary mixtures of antihypertensive drugs by RP-LC methods using two new generation silica columns.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 72

    Topics: Antihypertensive Agents; Captopril; Chromatography, Reverse-Phase; Hydrochlorothiazide; Imidazoles; Indicators and Reagents; Silicon Dioxide; Solvents; Tetrazoles

2013
Protective effect of captopril, olmesartan, melatonin and compound 21 on doxorubicin-induced nephrotoxicity in rats.
    Physiological research, 2013, Volume: 62, Issue:Suppl 1

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Doxorubicin; Glomerular Filtration Rate; Imidazoles; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 2; Renal Agents; Renal Insufficiency, Chronic; Tetrazoles; Treatment Outcome

2013
Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice.
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Autophagy; Blood Pressure; Captopril; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Metoprolol; Mice, Inbred C57BL; Myocytes, Cardiac; Signal Transduction; Tetrazoles; Ventricular Function, Left; Ventricular Remodeling

2015
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
    The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23

    Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2016