Page last updated: 2024-09-04

olmesartan and candesartan

olmesartan has been researched along with candesartan in 39 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(candesartan)
Trials
(candesartan)
Recent Studies (post-2010) (candesartan)
8411855541,929412589

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)candesartan (IC50)
Epidermal growth factor receptorHomo sapiens (human)3.2769
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)5.9472
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.0652
Cytochrome P450 3A4Homo sapiens (human)9
Adenosine receptor A3Homo sapiens (human)1.2199
Cytochrome P450 2C9 Homo sapiens (human)3
Beta-3 adrenergic receptorHomo sapiens (human)4.3
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.2199
Alpha-2B adrenergic receptorHomo sapiens (human)3.843
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.0652
Thromboxane-A synthase Homo sapiens (human)3.0594
Type-1 angiotensin II receptorHomo sapiens (human)0.0405
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.2199

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (17.95)29.6817
2010's28 (71.79)24.3611
2020's4 (10.26)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Ekins, S; Williams, AJ; Xu, JJ1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM1
Foster, H; Foster, R; Philippou, H; Wilson, C1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Asano, Y; Fujita, M; Hirata, YL; Kim, J; Kitakaze, M; Minamino, T; Miyatsuka, T; Okuda, H; Takashima, S; Tomoike, H; Tsukamoto, O1
Hamamoto, Y; Honjo, S; Ikeda, H; Koshiyama, H; Nabe, K; Wada, Y1
Imai, K; Tsunoda, M; Yamagishi, M; Yanagisawa, T1
Kuji, T; Masuda, S; Okano, Y; Tamura, K; Tochikubo, O; Umemura, S1
Falvey, H; Lowy, A; Müller, E; Nixon, RM1
Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T1
Masuda, S; Okano, Y; Ozawa, M; Tamura, K; Tochikubo, O; Umemura, S1
Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Gravina, A; Maffioli, P; Mereu, R; Palumbo, I; Salvadeo, SA1
Fujiwara, N; Koide, H; Nakamura, T; Sato, E; Sugaya, T; Ueda, Y1
Ge, J; Gong, H; Komuro, I; Li, L; Lin, L; Wu, J; Zhou, N; Zou, Y1
Friedrich, D; Gortner, L; Herkenrath, P; Hoppe, B; Hünseler, C; Kattner, E; Körber, F; Lindner, U; Müller, A; Oberthuer, A; Paneitz, A; Roth, B; Schaible, T; Schmitt, K; Welzing, L1
Belsey, JD1
Asai, S; Nakayama, T; Nishida, Y; Soma, M; Takahashi, Y1
Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I1
Hasegawa, H; Kameda, Y; Kobayashi, Y; Komuro, I; Kubota, A; Takano, H1
Daikuhara, H; Ishida, T; Kikuchi, F1
Afantitis, A; Baldus, J; Christodouleas, D; Fotakis, C; Glaubitz, C; Hodzic, A; Kritsi, E; Mali, G; Mavromoustakos, T; Megariotis, G; Melagraki, G; Ntountaniotis, D; Pabst, G; Papadopoulos, MG; Potamitis, C; Rappolt, M; Zervou, M; Zoumpoulakis, P1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T1
Bramlage, P; Fimmers, R; Gansz, A; Lüders, S; Nadal, J; Schmieder, RE; Schrader, J; Sturm, CD; Zemmrich, C2
Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC1
Daikuhara, H; Fukunaga, K; Ohshima, T1
Komano, H; Liu, J; Liu, S; Maeda, T; Tanabe, C; Zou, K1
Asner, R; Bayer, A; Kopf, W; Letzel, M; Schüssler, W; Sengl, M; Weiß, K1
Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H1
Etoh, T; Kita, T; Kitamura, K; Nakada, S; Ohya, Y; Sakima, A; Shimokubo, T; Takishita, S; Tamaki, N; Yokota, N1
Bayer, A; Greco, G; Grosse, S; Heermann, A; Letzel, M; Letzel, T; Lucke, T; Schulz, W; Schüssler, W; Sengl, M1
Asayama, K; Haga, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Mano, N; Metoki, H; Murakami, T; Obara, T; Ohkubo, T; Satoh, M1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G1
Busby, J; Cardwell, CR; Hughes, C; Johnston, BT; McMenamin, Ú; Spence, A1
Jóźwiak, K; Kocki, T; Targowska-Duda, KM; Turski, WA; Wnorowski, A; Zakrocka, I1
Lauder, L; Mahfoud, F; Meyer, MR; Vollmer, AC; Wagmann, L1

Reviews

2 review(s) available for olmesartan and candesartan

ArticleYear
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan

2010
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.
    International journal of clinical practice, 2009, Volume: 63, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009

Trials

13 trial(s) available for olmesartan and candesartan

ArticleYear
Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes.
    Diabetes research and clinical practice, 2009, Volume: 83, Issue:1

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan

2009
Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Autonomic Nervous System; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Health Surveys; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Telmisartan; Tetrazoles; Valine; Valsartan

2009
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Tetrazoles

2010
Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:8

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Sympathetic Nervous System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Differential effects of candesartan and olmesartan on adipose tissue activity biomarkers in type II diabetic hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:8

    Topics: Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Female; Glycemic Index; Humans; Hypertension; Hypoglycemic Agents; Imidazoles; Insulin Resistance; Male; Middle Aged; Tetrazoles

2010
Renoprotective Effects of Various Angiotensin II Receptor Blockers in Patients with Early-Stage Diabetic Nephropathy.
    Kidney & blood pressure research, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fatty Acid-Binding Proteins; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Treatment Outcome

2010
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2011, Volume: 17, Issue:5

    Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Benzimidazoles; Biphenyl Compounds; Cardiac Surgical Procedures; Compliance; Drug Substitution; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome

2011
Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:2

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Hypertension; Imidazoles; Japan; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2012
The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
    Diabetes & vascular disease research, 2012, Volume: 9, Issue:4

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heart Rate; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome

2012
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2013
Daytime systolic ambulatory blood pressure with a direct switch between candesartan monotherapy and the fixed-dose combination olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-1).
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:11

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Systole; Tetrazoles; Treatment Outcome

2013
Daytime systolic ambulatory blood pressure with a two-step switch from candesartan to olmesartan monotherapy and the fixed-dose combination of olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-2).
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; White People

2014
Difference in the effects of switching from candesartan to olmesartan or telmisartan to olmesartan in hypertensive patients with type 2 diabetes: the COTO study.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Telmisartan; Tetrazoles

2014

Other Studies

24 other study(ies) available for olmesartan and candesartan

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents

2011
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.
    European journal of medicinal chemistry, 2020, Jun-01, Volume: 195

    Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan

2020
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
    Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21

    Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Blockade of angiotensin II receptors reduces the expression of receptors for advanced glycation end products in human endothelial cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Endothelial Cells; Gene Silencing; Humans; Imidazoles; NF-kappa B; Promoter Regions, Genetic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1

2006
Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice.
    Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:4

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Heart Rate; Imidazoles; Luminescence; Male; Mice; Mice, Inbred C57BL; Nicardipine; Nitroprusside; Oxalates; Reproducibility of Results; Sensitivity and Specificity; Tetrazoles; Time Factors

2009
Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:12

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Echocardiography; Gene Expression; Hemodynamics; Imidazoles; Losartan; Male; Mice; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Angiotensin II receptor blocker induced fetopathy: 7 cases.
    Klinische Padiatrie, 2011, Volume: 223, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Apgar Score; Benzimidazoles; Biphenyl Compounds; Female; Fetal Growth Retardation; Humans; Hypertension, Pregnancy-Induced; Hypertension, Pulmonary; Imidazoles; Infant, Newborn; Kidney; Lung; Male; Oligohydramnios; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Renal Insufficiency; Skull; Tetrazoles; Ultrasonography, Prenatal; Valine; Valsartan

2011
Choice of angiotensin receptor blocker in moderate hypertension. A UK-based cost-benefit comparison of olmesartan- and candesartan-based regimens.
    Journal of medical economics, 2011, Volume: 14, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cohort Studies; Cost-Benefit Analysis; Decision Making; Humans; Hypertension; Imidazoles; Outcome Assessment, Health Care; Tetrazoles; United Kingdom

2011
Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study.
    Cardiovascular diabetology, 2011, Aug-10, Volume: 10

    Topics: Aged; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Urea Nitrogen; Cholesterol; Cholesterol, LDL; Cohort Studies; Creatinine; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Hypertension; Imidazoles; Kidney; Lipid Metabolism; Male; Middle Aged; Potassium; Retrospective Studies; Tetrazoles; Triglycerides

2011
Comparative study of the AT₁ receptor prodrug antagonist candesartan cilexetil with other sartans on the interactions with membrane bilayers.
    Biochimica et biophysica acta, 2012, Volume: 1818, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cell Membrane; Imidazoles; Lipid Bilayers; Molecular Conformation; Receptor, Angiotensin, Type 1; Tetrazoles; Thermodynamics; Valine; Valsartan

2012
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:5

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2014
Differential effects of angiotensin II receptor blockers on Aβ generation.
    Neuroscience letters, 2014, May-01, Volume: 567

    Topics: Amyloid beta-Peptides; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Fibroblasts; Imidazoles; Losartan; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Phosphatidylinositol 3-Kinases; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Tetrazoles; Valine; Valsartan

2014
Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment.
    Environmental science and pollution research international, 2014, Volume: 21, Issue:18

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biodegradation, Environmental; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Germany; Imidazoles; Irbesartan; Mass Spectrometry; Molecular Structure; Rivers; Tetrazoles; Thiophenes; Valine; Valsartan; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2014
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:3

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan

2015
Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:7

    Topics: Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Sectional Studies; Female; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Therapeutic Equivalency

2015
LC-MS screening techniques for wastewater analysis and analytical data handling strategies: Sartans and their transformation products as an example.
    Chemosphere, 2015, Volume: 137

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Imidazoles; Irbesartan; Laboratories; Mass Spectrometry; Tetrazoles; Wastewater; Water Pollutants, Chemical; Water Purification; Workflow

2015
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements.
    Journal of hypertension, 2016, Volume: 34, Issue:6

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan

2016
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
    The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23

    Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2016
Angiotensin receptor blocker use and gastro-oesophageal cancer survival: a population-based cohort study.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Child; Child, Preschool; Cohort Studies; Diabetic Neuropathies; Esophageal Neoplasms; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Infant; Infant, Newborn; Losartan; Male; Middle Aged; Registries; Stomach Neoplasms; Survival Analysis; Tetrazoles; Young Adult

2018
Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kynurenic Acid; Losartan; Male; Rats, Wistar; Telmisartan; Tetrazoles; Transaminases; Valsartan

2019
Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis.
    Molecules (Basel, Switzerland), 2021, Mar-09, Volume: 26, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Fluids; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Hypertension; Imidazoles; Liquid-Liquid Extraction; Metoprolol; Patient Compliance; Pilot Projects; Plasma; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles

2021