Page last updated: 2024-09-04

olmesartan and avapro

olmesartan has been researched along with avapro in 26 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(avapro)
Trials
(avapro)
Recent Studies (post-2010) (avapro)
8411855541,369385495

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)avapro (IC50)
Bile salt export pumpHomo sapiens (human)7.3067
Type-1 angiotensin II receptorHomo sapiens (human)0.0099
Type-2 angiotensin II receptorHomo sapiens (human)0.003

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (11.54)29.6817
2010's18 (69.23)24.3611
2020's5 (19.23)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Ekins, S; Williams, AJ; Xu, JJ1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM1
Foster, H; Foster, R; Philippou, H; Wilson, C1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bahlmann, FH; de Groot, K; Fliser, D; Haller, H; Hertel, B; Mueller, O1
Falvey, H; Lowy, A; Müller, E; Nixon, RM1
Burnier, M; Coltamai, L; Maillard, M; Simon, A; Vogt, B1
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J1
Elisaf, MS; Florentin, M; Kostapanos, MS; Kostara, CE; Liberopoulos, EN; Milionis, HJ; Rizos, CV1
Aller, R; Castro, MJ; Conde, R; De Luis, DA; Gonzalez Sagrado, M; Izaola, O; Perez Castrillon, JL; Romero, E1
Biskupiak, J; Qian, C; Quah, R; Ram, CV; Ramaswamy, K; Russo, PA; Ryan, A1
Arimura, T; Miura, S; Morii, J; Sako, H; Saku, K; Shiga, Y; Sugihara, M; Uehara, Y; Zhang, B1
Ike, A; Iwata, A; Kawamura, A; Miura, S; Morii, J; Nishikawa, H; Saku, K; Shiga, Y; Sugihara, M1
Allen, RR; Ghushchyan, V; Kaila, S; Nair, KV; Saseen, JJ1
DiNicolantonio, JJ; Elisaf, MS; Liberopoulos, EN; Rizos, CV; Tellis, K; Tselepis, AD1
Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC1
Asner, R; Bayer, A; Kopf, W; Letzel, M; Schüssler, W; Sengl, M; Weiß, K1
Bayer, A; Greco, G; Grosse, S; Heermann, A; Letzel, M; Letzel, T; Lucke, T; Schulz, W; Schüssler, W; Sengl, M1
Asayama, K; Haga, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Mano, N; Metoki, H; Murakami, T; Obara, T; Ohkubo, T; Satoh, M1
Guo, CX; Li, X; Liu, JY; Liu, SK; Liu, ZQ; Luo, M; Pei, Q; Xie, P; Yang, GP; Yin, JY; Zheng, Y; Zhou, HH1
Jóźwiak, K; Kocki, T; Targowska-Duda, KM; Turski, WA; Wnorowski, A; Zakrocka, I1
Kim, H; Kim, HS; Kim, JH; Lee, SH1
Ahn, B; Hall, SE; Hinkley, JM; Hyatt, H; Morton, AB; Powers, SK; Smuder, AJ; Sollanek, KJ; Wiggs, MP1

Reviews

2 review(s) available for olmesartan and avapro

ArticleYear
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan

2010
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.
    International journal of clinical practice, 2009, Volume: 63, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009

Trials

7 trial(s) available for olmesartan and avapro

ArticleYear
Stimulation of endothelial progenitor cells: a new putative therapeutic effect of angiotensin II receptor antagonists.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cell Count; Diabetes Mellitus, Type 2; Double-Blind Method; Endothelial Cells; Female; Hematopoietic Stem Cells; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Prospective Studies; Tetrazoles

2005
Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans.
    Journal of hypertension, 2010, Volume: 28, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Kidney Tubules; Losartan; Single-Blind Method; Tetrazoles; Valine; Valsartan

2010
Effects of rosuvastatin combined with olmesartan, irbesartan, or telmisartan on indices of glucose metabolism in Greek adults with impaired fasting glucose, hypertension, and mixed hyperlipidemia: a 24-week, randomized, open-label, prospective study.
    Clinical therapeutics, 2010, Volume: 32, Issue:3

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; C-Reactive Protein; Drug Therapy, Combination; Fasting; Female; Fluorobenzenes; Greece; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Imidazoles; Insulin; Irbesartan; Male; Middle Aged; Prospective Studies; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Telmisartan; Tetrazoles

2010
Effects of olmesartan vs irbesartan on metabolic parameters and visfatin in hypertensive obese women.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:9

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Cholesterol; Cytokines; Female; Humans; Hypertension; Imidazoles; Insulin; Irbesartan; Middle Aged; Nicotinamide Phosphoribosyltransferase; Obesity; Prospective Studies; Spain; Tetrazoles; Time Factors; Treatment Outcome; Triglycerides

2010
Comparison of the efficacy and safety of irbesartan and olmesartan in patients with hypertension (EARTH study).
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:5

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Irbesartan; Male; Middle Aged; Tetrazoles

2012
Comparison of the efficacies of irbesartan and olmesartan after successful coronary stent implantation.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:7

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Drug-Eluting Stents; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Percutaneous Coronary Intervention; Tetrazoles; Treatment Outcome

2013
Combining rosuvastatin with angiotensin-receptor blockers of different PPARγ-activating capacity: effects on high-density lipoprotein subfractions and associated enzymes.
    Angiology, 2015, Volume: 66, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Angiotensin II Type 1 Receptor Blockers; Aryldialkylphosphatase; Benzimidazoles; Benzoates; Biomarkers; Biphenyl Compounds; Cholesterol, HDL; Drug Therapy, Combination; Dyslipidemias; Female; Fluorobenzenes; Greece; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Irbesartan; Lipoproteins, HDL; Male; Middle Aged; PPAR gamma; Prediabetic State; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Telmisartan; Tetrazoles; Treatment Outcome

2015

Other Studies

17 other study(ies) available for olmesartan and avapro

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents

2011
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.
    European journal of medicinal chemistry, 2020, Jun-01, Volume: 195

    Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan

2020
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
    Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21

    Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.
    Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:2-3

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes

2010
Blood pressure outcomes in patients receiving angiotensin II receptor blockers in primary care: a comparative effectiveness analysis from electronic medical record data.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Black or African American; Blood Pressure; Diabetes Mellitus; Electronic Health Records; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Obesity; Primary Health Care; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People; Young Adult

2011
Maintaining goal blood pressures after switching from olmesartan to other angiotensin receptor blockers.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:12

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Substitution; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan

2013
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:5

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2014
Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment.
    Environmental science and pollution research international, 2014, Volume: 21, Issue:18

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biodegradation, Environmental; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Germany; Imidazoles; Irbesartan; Mass Spectrometry; Molecular Structure; Rivers; Tetrazoles; Thiophenes; Valine; Valsartan; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2014
LC-MS screening techniques for wastewater analysis and analytical data handling strategies: Sartans and their transformation products as an example.
    Chemosphere, 2015, Volume: 137

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Imidazoles; Irbesartan; Laboratories; Mass Spectrometry; Tetrazoles; Wastewater; Water Pollutants, Chemical; Water Purification; Workflow

2015
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements.
    Journal of hypertension, 2016, Volume: 34, Issue:6

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan

2016
Repaglinide-irbesartan drug interaction: effects of SLCO1B1 polymorphism on repaglinide pharmacokinetics and pharmacodynamics in Chinese population.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:8

    Topics: Adult; Asian People; Biphenyl Compounds; Blood Glucose; Carbamates; Cells, Cultured; China; Dose-Response Relationship, Drug; Drug Interactions; Genotype; Healthy Volunteers; Humans; Imidazoles; Irbesartan; Liver-Specific Organic Anion Transporter 1; Losartan; Male; Piperidines; Polymorphism, Single Nucleotide; Tetrazoles; Valsartan; Young Adult

2018
Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kynurenic Acid; Losartan; Male; Rats, Wistar; Telmisartan; Tetrazoles; Transaminases; Valsartan

2019
Comparative analysis of the efficacy of angiotensin II receptor blockers for uric acid level change in asymptomatic hyperuricaemia.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:6

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cohort Studies; Female; Humans; Hyperuricemia; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Retrospective Studies; Tetrazoles; Time Factors; Uric Acid

2020
Comparative Efficacy of Angiotensin II Type 1 Receptor Blockers Against Ventilator-Induced Diaphragm Dysfunction in Rats.
    Clinical and translational science, 2021, Volume: 14, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrophy; Diaphragm; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Imidazoles; Irbesartan; Rats; Respiration, Artificial; Tetrazoles; Ventilators, Mechanical

2021